Scientists / Publications

Publications

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DISPLAYING 5901 - 5950 OF 15657 RESULTS

Work disability, lost productivity and associated risk factors in patients diagnosed with systemic lupus erythematosus
Lupus Science and Medicine, ISSN: 20538790
Tammy O. Utset; Amrutha Baskaran; Barbara Segal; Laura Trupin; Sarika Ogale; Ellen Herberich; Kenneth C. Kalunian
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Glycogen synthase kinase-3 (Gsk-3) plays a fundamental role in maintaining DNA methylation at imprinted loci in mouse embryonic stem cells
Molecular Biology of the Cell, ISSN: 19394586 10591524
Gavin D. Meredith; Anthony D'Ippolito; Miroslav Dudas; Leigh C. Zeidner; Logan Hostetter; Kelsie Faulds; Thomas H. Arnold; Anthony P. Popkie; Brad Doble; George Marnellos; Christopher Adams; Yulei Wang; Christopher J. Phiel
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Key challenges for the creation and maintenance of specialist protein resources
Proteins: Structure, Function and Bioinformatics, ISSN: 10970134 08873585
Gemma L. Holliday; Amos Bairoch; Pantelis G. Bagos; Arnaud Chatonnet; David J. Craik; Robert D. Finn; Bernard Henrissat; David Landsman; Gerard Manning; Nozomi Nagano; Claire O'Donovan; Kim D. Pruitt; Neil D. Rawlings; Milton H. Saier Jr.; Ramanathan Sowdhamini; Michael Spedding; Narayanaswamy Srinivasan; Gerrit Vriend; Patricia C. Babbitt; Alex Bateman
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The Lifetime Economic Burden of Inaccurate HER2 Testing: Estimating the Costs of False-Positive and False-Negative HER2 Test Results in US Patients with Early-Stage Breast Cancer
Value in Health, ISSN: 15244733 10983015
Louis P. Garrison Jr.; Joseph B. Babigumira; Anthony Masaquel; Bruce Wang; Deepa Lalla; Melissa Brammer
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RIPK1 and RIPK3: Critical regulators of inflammation and cell death
Trends in Cell Biology, ISSN: 18793088 09628924
Kim Newton
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Cryomilling-induced solid dispersion of poor glass forming/poorly water-soluble mefenamic acid with polyvinylpyrrolidone K12
Drug Development and Industrial Pharmacy, ISSN: 15205762 03639045
Naewon Kang; Jangmi Lee; Ji Na Choi; Chen Mao; Eun Hee Lee
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Omalizumab adherence in an observational study of patients with moderate to severe allergic asthma
Annals of Allergy, Asthma and Immunology, ISSN: 15344436 10811206
Susan L. Janson; Paul G. Solari; Benjamin L. Trzaskoma; Hubert Chen; Tmirah Haselkorn; James L. Zazzali
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Outcomes of nonsevere relapses in antineutrophil cytoplasmic antibody-associated vasculitis treated with glucocorticoids
Arthritis and Rheumatology, ISSN: 23265205 23265191
Miloslavsky; Specks; Merkel; Seo; Spiera; Langford; Hoffman; Cees Kallenberg; St.clair; Tchao; Linna Ding; Iklé; Villareal; Noha Lim; Paul Brunetta; Fervenza; Monach; John H. Stone
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Brothers in arms: BioPharma and CROs collaborating in early drug discovery
Drug Discovery World, ISSN: 14694344
John Montana; Cornelis E. Hop
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Dose-dependent exposure and metabolism of GNE-892, a β-secretase inhibitor, in monkeys: Contributions by P450, AO, and P-gp
European Journal of Drug Metabolism and Pharmacokinetics, ISSN: 21070180 03787966
Ryan Takahashi; Shuguang Ma; Qin Yue; Heasook Kim-Kang; Yijun Yi; Joseph P. Lyssikatos; Kelly Regal; Kevin W. Hunt; Nicholas C. Kallan; Michael Siu; Cornelis E. Hop; Xingrong Liu; S. Cyrus Khojasteh
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An Anti-B7-H4 antibody-drug conjugate for the treatment of breast cancer
Molecular Pharmaceutics, ISSN: 15438392 15438384
Leong; Wei-Ching Liang; Yan Wu; Lisa Crocker; Eric Cheng; Deepak Sampath; Rachana Ohri; Helga Raab; Hass; Thinh Q. Pham; Ron Firestein; Dongwei Li; Melissa Schutten; Nicola J. Stagg; Annie Ogasawara; Neelima Koppada; Roth; Simon P. Williams; Byoung-Chul Lee; Cecile Chalouni; Ivan Peng; Jason Devoss; Jarrod Tremayne; Paul G. Polakis; Andrew G. Polson
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Therapeutic targeting of Bcl-2 family for treatment of B-cell malignancies
Expert Review of Hematology, ISSN: 17474094 17474086
Jane Huang; Wayne J. Fairbrother; John C. Reed
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Characteristics Associated with Biologic Monotherapy Use in Biologic-Naive Patients with Rheumatoid Arthritis in a US Registry Population
Rheumatology and Therapy, ISSN: 21986584 21986576
Dimitrios A. Pappas; Reed; Katherine C. Saunders; Ani John; Ashwini Shewade; Jeffrey D. Greenberg; Joel M. Kremer
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A cysteine-clamp gene drives embryo polarity in the midge Chironomus
Science, ISSN: 10959203 00368075
Jeff Klomp; Derek Athy; Chun Wai Kwan; Natasha I. Bloch; Thomas Sandmann; Steffen Lemke; Urs Schmidt-Ott
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The discovery and characterization of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor potentiator N-{(3 S,4 S)-4-[4-(5-cyano-2-thienyl)phenoxy]tetrahydrofuran-3-yl}propane-2-sulfonamide (PF-04958242)
Journal of Medicinal Chemistry, ISSN: 15204804 00222623
Christopher L. Shaffer; Nandini C. Patel; Jacob B. Schwarz; Renato J. Scialis; Yunjing Wei; Xinjun J. Hou; Longfei Xie; Kapil Karki; Dianne K. Bryce; Sarah M. Osgood; William E. Hoffmann; John T. Lazzaro; Cheng Chang; Dina F. McGinnis; Susan M. Lotarski; Jianhua Liu; R. Scott Obach; Mark L. Weber; Laigao Chen; Kenneth R. Zasadny; Patricia A. Seymour; Christopher J. Schmidt; Mihály Hajós; Raymond S. Hurst; Jayvardhan Pandit; Christopher J. O'Donnell
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Reproducibility: Changing the policies and culture of cell line authentication
Nature Methods, ISSN: 15487105 15487091
Leonard P. Freedman; Mark C. Gibson; Stephen P. Ethier; Howard R. Soule; Richard M. Neve; Yvonne A. Reid
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SomaticSignatures: Inferring mutational signatures from single-nucleotide variants
Bioinformatics, ISSN: 14602059 13674803
Julian S. Gehring; Bernd Fischer; Michael Lawrence; Wolfgang Huber
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CNS Anticancer Drug Discovery and Development Conference White Paper
Neuro-Oncology, ISSN: 15235866 15228517
Victor A. Levin; Peter J. Tonge; James M. Gallo; Marc R. Birtwistle; Arvin C. Dar; Antonio Iavarone; Patrick J. Paddison; Timothy P. Heffron; William F. Elmquist; Jean E. Lachowicz; Ted W. Johnson; Forest M. White; Joohee Sul; Smith; Wang Shen; Jann N. Sarkaria; Ramakrishna Samala; Patrick Y. Wen; Donald A. Berry; Russell C. Petter
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Registered report: Coadministration of a tumor-penetrating peptide enhances the efficacy of cancer drugs
eLife, ISSN: 2050084X
Irawati Kandela; James Chou; Kartoa Chow; Elizabeth Iorns; William Gunn; Fraser Tan; Nicole Perfito; Timothy Errington
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Clinical outcomes with bevacizumab-containing and non-bevacizumab–containing regimens in patients with recurrent glioblastoma from US community practices
Journal of Neuro-Oncology, ISSN: 15737373 0167594X
Clara Chen; Arliene Ravelo; Elaine B. Yu; Rahul Dhanda; Ian Schnadig
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Neo approaches to cancer vaccines
Science, ISSN: 10959203 00368075
Lélia Delamarre; Ira Mellman; Mahesh Yadav
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Tetrahydroindazoles as interleukin-2 inducible T-cell kinase inhibitors. Part II. Second-generation analogues with enhanced potency, selectivity, and pharmacodynamic modulation in vivo
Journal of Medicinal Chemistry, ISSN: 15204804 00222623
Jason D. Burch; Kathy Barrett; Yuan Chen; Jason Devoss; Eigenbrot; Richard Goldsmith; Moulay Hicham Alaoui Ismaili; Kevin Lau; Zhonghua Lin; Daniel F. Ortwine; Ali A. Zarrin; Paul A. McEwan; John J. Barker; Claire Ellebrandt; Daniel Kordt; Daniel B. Stein; Xiaolu Wang; Yong Chen; Baihua Hu; Xiaofeng Xu; Po-Wai Yuen; Yamin Zhang; Zhonghua Pei
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EPZ011989, A potent, orally-available EZH2 inhibitor with robust in vivo activity
ACS Medicinal Chemistry Letters, ISSN: 19485875
John E. Campbell; Kevin W. Kuntz; Sarah K. Knutson; Natalie M. Warholic; Heike Keilhack; Tim J. Wigle; Alejandra Raimondi; Christine R. Klaus; Nathalie Rioux; Akira Yokoi; Satoshi Kawano; Yukinori Minoshima; Hyeong-Wook Choi; Margaret Porter Scott; Nigel J. Waters; Jesse J. Smith; Richard Chesworth; Mikel P. Moyer; Robert A. Copeland
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Anti-CD20/CD3 T cell-dependent bispecific antibody for the treatment of B cell malignancies
Science Translational Medicine, ISSN: 19466242 19466234
Liping L. Sun; Diego Ellerman; Mary Mathieu; Maria Hristopoulos; Xiaocheng Chen; Yijin Li; Xiaojie Yan; Robyn Clark; Arthur Reyes; Stefanich; Elaine Mai; Judy Young; Clarissa Johnson; Mahrukh Huseni; Xinhua Wang; Chen; Peiyin Wang; Hong Wang; Noel Dybdal; Yu-Waye Chu; Nicholas Chiorazzi; Justin M. Scheer; Teemu T. Junttila; Klara Totpal; Dennis; Allen Ebens
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Erratum to Modeling precision treatment of breast cancer [Genome Biology, 14, (2013), R110]
Genome Biology, ISSN: 1474760X 14747596
Anneleen Daemen; Obi L. Griffith; Laura M. Heiser; Nicholas J. Wang; Oana M. Enache; Zachary Sanborn; Francois Pepin; Durinck; James E. Korkola; Malachi Griffith; Joe S. Hur; Nam Huh; Jongsuk Chung; Leslie Cope; Mary Jo Fackler; Christopher Umbricht; Saraswati Sukumar; Pankaj Seth; Vikas P. Sukhatme; Lakshmi Jakkula; Yiling Lu; Gordon B. Mills; Raymond J Cho; Eric A. Collisson; Laura J. van't Veer; Paul T. Spellman; Joe W. Gray
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A site of varicella-zoster virus vulnerability identified by structural studies of neutralizing antibodies bound to the glycoprotein complex gHgL
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 10916490 00278424
Yi Xing; Stefan L. Oliver; TuongVi Nguyen; Claudio Ciferri; Avishek Nandi; Julie Hickman; Cinzia Giovani; Edward Yang; Giuseppe Palladino; Charles Grose; Yasushi Uematsu; Anders E. Lilja; Ann M. Arvin; Andrea Carfi
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Castration-resistant Lgr5+ cells are long-lived stem cells required for prostatic regeneration
Stem Cell Reports, ISSN: 22136711
Bu-Er Wang; Xi Wang; Jason E. Long; Jeffrey Eastham-Anderson; Ron Firestein; Melissa Junttila
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A size exclusion-reversed phase two dimensional-liquid chromatography methodology for stability and small molecule related species in antibody drug conjugates
Journal of Chromatography A, ISSN: 18733778 00219673
Yi Li; Christine Gu; Jason Gruenhagen; Kelly Zhang; Peter M. Yehl; Nik P. Chetwyn; Colin D. Medley
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Translational value of mouse models in oncology drug development
Nature Medicine, ISSN: 1546170X 10788956
Stephen Gould; Melissa Junttila; Frederic J. De Sauvage
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Enhancing the antitumor efficacy of a cell-surface death ligand by covalent membrane display
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 10916490 00278424
Pradeep Nair; Heather Flores; Alvin Gogineni; Scot A. Marsters; David Lawrence; Robert F. Kelley; Hai Ngu; Meredith Sagolla; László Kömüves; Richard Bourgon; Jeffrey Settleman; Avi Ashkenazi
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Effect of ketoconazole and diltiazem on the pharmacokinetics of apixaban, an oral direct factor Xa inhibitor
British Journal of Clinical Pharmacology, ISSN: 13652125 03065251
Charles E. Frost; Wonkyung Byon; Yan Song; Jessie Wang; Alan E. Schuster; Rebecca A. Boyd; Donglu Zhang; Zhigang Yu; Clapton Dias; Andrew Shenker; Frank Lacreta
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Interpretation of meta-analysis evaluating progression-free survival as a surrogate endpoint for overall survival in glioblastoma
Neuro-Oncology, ISSN: 15235866 15228517
Kelong Han; Melanie Ren; Wick; Lauren E. Abrey; Asha Das; Jin Y. Jin; David A. Reardon
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High resolution separation of recombinant monoclonal antibodies by size-exclusion ultra-high performance liquid chromatography (SE-UHPLC)
Journal of Pharmaceutical and Biomedical Analysis, ISSN: 1873264X 07317085
Renee Yang; Yun Tang; Bing Zhang; Xuemei Lu; Alice Liu; Taylor Zhang
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Development and applications of AlphaScreen-based FcRn binding assay to characterize monoclonal antibodies
Journal of Immunological Methods, ISSN: 18727905 00221759
Qiang Wu; Ho Young Lee; Wong; Guoying Jiang; Hélène Gazzano-Santoro
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PTEN loss is associated with worse outcome in HER2-Amplified breast cancer patients but is not associated with trastuzumab resistance
Clinical Cancer Research, ISSN: 15573265 10780432
Howard M. Stern; Humphrey Gardner; Tomasz Burzykowski; Wafaa Elatre; Carol O'Brien; Lackner; Gary A. Pestano; Angela Santiago; Ivonne Villalobos; Wolfgang Eiermann; Tadeusz Pienkowski; Miguel Martín; Nicholas J. Robert; John Crown; Nuciforo; Valerie Bée; John Mackey; Dennis J. Slamon; Michael F. Press
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MET Suppresses Epithelial VEGFR2 via Intracrine VEGF-induced Endoplasmic Reticulum-associated Degradation
EBioMedicine, ISSN: 23523964
Tom T. Chen; Ellen H. Filvaroff; Jing Peng; Scot A. Marsters; Adrian M. Jubb; Koeppen; Mark Merchant; Avi Ashkenazi
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Humoral immune response to vaccines in patients with rheumatoid arthritis treated with tocilizumab: Results of a randomised controlled trial (VISARA)
Annals of the Rheumatic Diseases, ISSN: 14682060 00034967
Bingham; Warren Rizzo; Alan Kivitz; Azra Hassanali; Ruchi Upmanyu; Micki Klearman
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Antibody positron emission tomography imaging in anticancer drug development
Journal of Clinical Oncology, ISSN: 15277755 0732183X
Laetitia E. Lamberts; Simon P. Williams; Anton G. T. Terwisscha Van Scheltinga; Marjolijn N. Lub-De Hooge; Carolien P. Schröder; Jourik A. Gietema; Adrienne H. Brouwers; Elisabeth G. E. De Vries
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Lactosylceramide-accumulation in lipid-rafts mediate aberrant-autophagy, inflammation and apoptosis in cigarette smoke induced emphysema
Apoptosis, ISSN: 1573675X 13608185
Manish Bodas; Taehong Min; Neeraj Vij
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Protection of Human myeloid dendritic cell subsets against influenza a virus infection is differentially regulated upon TLR stimulation
Journal of Immunology, ISSN: 15506606 00221767
Faezzah Baharom; Saskia Thomas; Andrea Bieder; Maria Hellmér; Julia Volz; Kerrie J. Sandgren; Gerald M. McInerney; Gunilla B. Karlsson Hedestam; Ira Mellman; Anna Smed-Sörensen
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Clinical applications of choroidal imaging technologies
Indian Journal of Ophthalmology, ISSN: 19983689 03014738
Jay Chhablani; Giulio Barteselli
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Comparison of the effectiveness of frontline chemoimmunotherapy regimens for follicular lymphoma used in the United States
Leukemia and Lymphoma, ISSN: 10292403 10428194
Loretta J. Nastoupil; Sinha; Michelle Byrtek; Ryan Ziemiecki; Taylor; Jonathan W. Friedberg; Jean L. Koff; Brian K. Link; James R. Cerhan; Keith Dawson; Christopher R. Flowers
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Collagenase as an effective tool for drug quantitation in tissues
Bioanalysis, ISSN: 17576199 17576180
Ann R. Qin; Xiaorong Liang; Yuzhong Deng; Brian J. Dean; Sheerin Shahidi-Latham
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Caspase-11: Arming the guards against bacterial infection
Immunological Reviews, ISSN: 1600065X 01052896
Irma B. Stowe; Bettina L. Lee; Nobuhiko Kayagaki
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Allosteric modulation of proteinase 3 activity by anti-neutrophil cytoplasmic antibodies in granulomatosis with polyangiitis
Journal of Autoimmunity, ISSN: 10959157 08968411
Lisa C. Hinkofer; Amber M. Hummel; John H. Stone; Hoffman; Merkel; E. Robert F. Spiera; St.clair; W. Joseph McCune; John C. Davis; Specks; Dieter E. Jenne
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PI3 kinase/mTOR inhibition increases sensitivity of ER positive breast cancers to CDK4/6 inhibition by blocking cell cycle re-entry driven by cyclinD1 and inducing apoptosis
Annals of Oncology, ISSN: 15698041 09237534
Maria Teresa Herrera-Abreu; Uzma S. Asghar; Elliot; Alex Pearson; Michelle Nannini; Young; Deepak Sampath; Mitch Dowsett; Martin; Nicholas C. Turner
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PI3 kinase/mTOR inhibition increases sensitivity of ER positive breast cancers to CDK4/6 inhibition by blocking cell cycle re-entry driven by cyclinD1 and inducing apoptosis
Annals of Oncology, ISSN: 15698041 09237534
Maria Teresa Herrera-Abreu; Uzma S. Asghar; Elliot; Alex Pearson; Michelle Nannini; Young; Deepak Sampath; Mitch Dowsett; Martin; Nicholas C. Turner
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Filling of High-Concentration Monoclonal Antibody Formulations into Pre-filled Syringes: Investigating Formulation-Nozzle Interactions To Minimize Nozzle Clogging
PDA Journal of Pharmaceutical Science and Technology, ISSN: 19482124
Wendy Shieu; Oliver B. Stauch; Maa
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In reply
Oncologist, ISSN: 1549490X
Shidong Jia; Liangxuan Zhang; Gary J. Latham
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Health state utilities for chronic lymphocytic leukemia: Importance of prolonging progression-free survival
Leukemia and Lymphoma, ISSN: 10292403 10428194
Charlotte E. Kosmas; Sarah L. Shingler; Kunal Samanta; Christof Wiesner; Paul A. H. Moss; Ursula Becker; Andrew J. Lloyd
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