Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 10701 - 10750 OF 15598 RESULTS

Vascular endothelial growth factor co-ordinates proper development of lung epithelium and vasculature
Mechanisms of Development, ISSN: 09254773
Liqing Zhao; Ke Wang; Napoleone Ferrara; Thiennu H. Vu
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Airway generation-specific differences in the spatial distribution of immune cells and cytokines in allergen-challenged rhesus monkeys
Clinical and Experimental Allergy, ISSN: 09547894
Lisa A. Miller; Stephen D. Hurst; Coffman; Tyler; Stovall; Chou; Lei F. Putney; Gershwin; Edward S. Schelegle; Plopper; Dallas M. Hyde
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Angiogenesis is required for successful bone induction during distraction osteogenesis
Journal of Bone and Mineral Research, ISSN: 08840431
Tony D. Fang; Ali Salim; Wei Xia; Randall P. Nacamuli; Samira Guccione; Hanjoon M. Song; Richard A. D. Carano; Ellen H. Filvaroff; Mark D. Bednarski; Amato J. Giaccia; Michael T. Longaker
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Role of efflux pumps and metabolising enzymes in drug delivery
Expert Opinion on Drug Delivery, ISSN: 17425247
Suresh Katragadda; Balasubrahmanyam Budda; Banmeet S. Anand; Ashim K. Mitra
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Genentech error proofs its batch records
Quality Progress, ISSN: 0033524X
Robert Bottome; Richard C. H. Chua
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Gene polymorphisms and serological markers of patients with active Crohn's disease in a clinical trial of antisense to ICAM-1
Clinical and Experimental Immunology, ISSN: 00099104
Bruce R. Yacyshyn; Schievella; Sewell; Tami
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Expression profiling the human septin gene family
Journal of Pathology, ISSN: 00223417
Peter A. Hall; Kenneth Jung; Kenneth J. Hillan; S. E. Hilary Russell
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Multimodality expression profiling shows SEPT9 to be overexpressed in a wide range of human tumours
Oncogene, ISSN: 09509232
Michael Scott; Paula L. Hyland; Gordon McGregor; Kenneth J. Hillan; S. E. Hilary Russell; Peter A. Hall
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Association of k-ras, b-raf, and p53 status with the treatment effect of bevacizumab
Journal of the National Cancer Institute, ISSN: 00278874 14602105
William L. Ince; Adrian M. Jubb; Scott N. Holden; Holmgren; Tobin; Meera Sridhar; Herbert Hurwitz; Fairooz F. Kabbinavar; Novotny; Kenneth J. Hillan; Koeppen
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Association of k-ras, b-raf, and p53 status with the treatment effect of bevacizumab
Journal of the National Cancer Institute, ISSN: 00278874 14602105
William Ince; Adrian M. Jubb; Scott N. Holden; Holmgren; Tobin; Meera Sridhar; Herbert Hurwitz; Fairooz F. Kabbinavar; Novotny; Kenneth J. Hillan; Koeppen
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A method to estimate the variance of an endpoint from an on-going blinded trial
Statistics in Medicine, ISSN: 02776715
Biao Xing; Jitendra Ganju
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Performance of a membrane adsorber for trace impurity removal in biotechnology manufacturing
Journal of Chromatography A, ISSN: 00219673
Michael Phillips; Jason Cormier; Jennifer Ferrence; Chris Dowd; Robert Kiss; Herbert Lutz; Jeffrey Carter
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Positive and negative regulation of the IL-27 receptor during lymphoid cell activation
Journal of Immunology, ISSN: 00221767
Alejandro V. Villarino; Joseph Larkin III; Christiaan J. M. Saris; Andrew J. Caton; Sophie Lucas; Wong; Frederic J. De Sauvage; Christopher A. Hunter
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Exo84 and Sec5 are competitive regulatory Sec6/8 effectors to the RalA GTPase
EMBO Journal, ISSN: 02614189
Rongsheng Jin; Jagath R. Junutula; Hugo T. Matern; Karen E. Ervin; Richard H. Scheller; Axel T. Brünger
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Identification of Pax2-regulated genes by expression profiling of the mid-hindbrain organizer region
Development (Cambridge), ISSN: 09501991
Maxime Bouchard; David Grote; Sarah E. Craven; Qiong Sun; Peter Steinlein; Meinrad Busslinger
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Serine protease cathepsin G regulates adhesion-dependent neutrophil effector functions by modulating integrin clustering
Immunity, ISSN: 10747613
Sofia Z. Raptis; Steven D. Shapiro; Pamela M. Simmons; Alec M. Cheng; Christine T.N. Pham
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Immune response in silico (IRIS): Immune-specific genes identified from a compendium of microarray expression data
Genes and Immunity, ISSN: 14664879
Abbas Alexander; Daryl T. Baldwin; Yan Ma; Wenjun Ouyang; Austin L. Gurney; Flavius Martin; Sherman Fong; Menno Van Lookeren Campagne; Godowski; P. Mickey Williams; Andrew A. Chan; Hilary F. Clark
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Tumor immunity via homeostatic T cell proliferation: Mechanistic aspects and clinical perspectives
Springer Seminars in Immunopathology, ISSN: 03444325
Roberto Baccala; Rosana Gonzalez-Quintial; Wolfgang Dummer; Argyrios N. Theofilopoulos
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Estimating heterogeneity in random effects models for longitudinal data
Biometrical Journal, ISSN: 03233847
Annabelle Lemenuel-Diot; Mallet; Laveille; Rene Bruno
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Racial differences in reperfusion therapy use in patients hospitalized with myocardial infarction: A regional phenomenon
American Heart Journal, ISSN: 00028703
Saif S. Rathore; Paul D. Frederick; Nathan R. Every; Hal V. Barron; Harlan M. Krumholz
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Epidermal growth factor receptor, protein kinase B/Akt, and glioma response to erlotinib
Journal of the National Cancer Institute, ISSN: 00278874 14602105
Daphne A. Haas-Kogan; Michael D. Prados; Tarik Tihan; Eberhard; Nannette Jelluma; Nils D. Arvold; Rachel Baumber; Kathleen R. Lamborn; Ami Kapadia; Mary Malec; Mitchel S. Berger; David Stokoe
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Immune response in silico (IRIS): Immune-specific genes identified from a compendium of microarray expression data
Genes and Immunity, ISSN: 14664879
Abbas Alexander; Daryl T. Baldwin; Yan Ma; Wenjun Ouyang; Austin L. Gurney; Flavius Martin; Fong; Menno Van Lookeren Campagne; Godowski; P. Mickey Williams; Andrew A. Chan; Hilary F. Clark
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Multiplexed serum measurement of IgG, IgA, IgM, and IgE antibody responses to therapeutic biologicals
Immunological Investigations, ISSN: 08820139
Krista McCutcheon; Edward O'Hara; David T.W. Fei
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Molecular recognition by a binary code
Journal of Molecular Biology, ISSN: 00222836
Frederic A. Fellouse; Bing Li; Deanne M. Compaan; Andrew A. Peden; Sarah G. Hymowitz; Sachdev S. Sidhu
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Evaluation of different primary recovery methods for E. coli-derived recombinant human growth hormone and compatibility with further down-stream purification
Biotechnology and Bioengineering, ISSN: 00063592
Josefine Persson; Dana C. Andersen; Philip M. Lester
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An expression-based site of origin diagnostic method designed for clinical application to cancer of unknown origin
Cancer Research, ISSN: 00085472
Richard W. Tothill; Adam Kowalczyk; Danny Rischin; Alex Bousioutas; Izhak Haviv; Ryan K. Van Laar; Waring; John Zalcberg; Robyn Ward; Andrew V. Biankin; Robert L. Sutherland; Susan M. Henshall; Kwun Fong; Jonathan R. Pollack; David D.L. Bowtell; Andrew J. Holloway
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Selective knockdown of the long variant of cellular FLICE inhibitory protein augments death receptor-mediated caspase-8 activation and apoptosis
Journal of Biological Chemistry, ISSN: 00219258
Darcie Sharp; David Lawrence; Avi Ashkenazi
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A structure-based database of antibody variable domain diversity
Journal of Molecular Biology, ISSN: 00222836
Christopher J. Bond; Wiesmann; James C. Marsters Jr.; Sachdev S. Sidhu
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Tenecteplase in the treatment of thrombosed hemodialysis grafts
CardioVascular and Interventional Radiology, ISSN: 01741551
Abigail Falk; Kathy Harbour
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Synthetic lethality of retinoblastoma mutant cells in the Drosophila eye by mutation of a novel peptidyl prolyl isomerase gene
Genetics, ISSN: 00166731
Kyle A. Edgar; Marcia Belvin; Annette L. Parks; Kellie Whittaker; Matt B. Mahoney; Monique Nicoll; Christopher C. Park; Christopher G. Winter; Feng Chen; Kim Lickteig; Ferhad Ahmad; Hanife Esengil; Matthew V. Lorenzi; Amanda Norton; Brent A. Rupnow; Laleh Shayesteh; Mariano Tabios; Lynn M. Young; Pamela M. Carroll; Casey Kopczynski; Greg D. Plowman; Lori S. Friedman; Helen L. Francis-Lang
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PAK4 mediates morphological changes through the regulation of GEF-H1
Journal of Cell Science, ISSN: 00219533
Marinella G. Callow; Sergey Zozulya; Mikhail L. Gishizky; Bahija Jallal; Tod Smeal
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Disulfide locked variants of factor VIIa with a restricted β-strand conformation have enhanced enzymatic activity
Protein Science, ISSN: 09618368
Henry R. Maun; Eigenbrot; Helga Raab; David Arnott; Lilian Phu; Sherron L. Bullens; Lazarus
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GMAP: A genomic mapping and alignment program for mRNA and EST sequences
Bioinformatics, ISSN: 13674803
Thomas D Wu; Colin K. Watanabe
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A monoclonal antibody that inhibits mouse tissue factor function [7]
Journal of Thrombosis and Haemostasis, ISSN: 15387933 15387836
Daniel Kirchhofer; Paul Moran; Sherron L. Bullens; Franklin V. Peale Jr.; Bunting
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A novel E3 ubiquitin ligase TRAC-1 positively regulates T cell activation
Journal of Immunology, ISSN: 00221767
Haoran Zhao; Connie C. Li; Jorge Pardo; Peter C. Chu; Charlene X. Liao; Jianing Huang; John G. Dong; Xiulan Zhou; Qi Huang; Betty Huang; Mark K. Bennett; Susan M. Molineaux; Henry Lu; Sarkiz Daniel-Issakani; Donald G. Payan; Esteban S. Masuda
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Novel brain wiring functions for classical morphogens: A role as graded positional cues in axon guidance
Development (Cambridge), ISSN: 09501991
Frédéric Charron; Marc Tessier-Lavigne
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Tissue distribution and receptor-mediated clearance of anti-CD11a antibody in mice
Drug Metabolism and Disposition, ISSN: 00909556
Greg P. Coffey; Judy Fox; Susanne Pippig; Susan Palmieri; Barbara Reitz; Michelle Gonzales; Anahid Bakshi; Josette Padilla-Eagar; Fielder
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Comparison of the global structure and dynamics of native and unmodified tRNAval
Biochemistry, ISSN: 00062960
Annaleen Vermeulen; Scott A. McCallum; Arthur Pardi
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Non-enzymatic hinge region fragmentation of antibodies in solution
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, ISSN: 15700232
Cordoba; Bao-Jen Shyong; Deirdre Breen; Reed J. Harris
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γδ T cell homeostasis is controlled by IL-7 and IL-15 together with subset-specific factors
Journal of Immunology, ISSN: 00221767
Roberto Baccala; Deborah Witherden; Rosana Gonzalez-Quintial; Wolfgang Dummer; Charles D. Surh; Wendy L. Havran; Argyrios N. Theofilopoulos
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Napoleone Ferrara discusses Avastin™ and the future of anti-angiogenesis therapy
Drug Discovery Today, ISSN: 13596446
Ulrike Knies-Bamforth; Christopher Watson; Napoleone Ferrara
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Coregulator interactions with the thyroid hormone receptor
Molecular and Cellular Proteomics, ISSN: 15359476
Jamie M. R. Moore; R. Kiplin Guy
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Multiple protein interactions involving proposed extracellular loop domains of the tight junction protein occludin
Molecular Biology of the Cell, ISSN: 10591524
Asma Nusrat; G. Thomas Brown; Jeffrey Tom; Alex Drake; Tam T.T. Bui; Quan; Mrsny
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Safety and efficacy of intravitreal injection of ranibizumab in combination with verteporfin PDT on experimental choroidal neovascularization in the monkey
Archives of Ophthalmology, ISSN: 00039950
Deeba Husain; Ivana K. Kim; Danny Gauthier; Anne Marie Lane; Miltiadis K. Tsilimbaris; Eric Ezra; Edward Connolly; Norman Michaud; Evangelos S. Gragoudas; Charles A. O'Neill; Joseph Beyer; Joan W. Miller
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Identification of a massive reserve of hematopoietic progenitors in mice
Stem Cells and Development, ISSN: 15473287
Hal E. Broxmeyer; Scott Cooper; Lasky; Frederic J. De Sauvage
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Intramolecular cooperativity in a protein binding site assessed by combinatorial shotgun scanning mutagenesis
Journal of Molecular Biology, ISSN: 00222836
Gábor Pál; Ultsch; Clark; Bridget Currell; Anthony A. Kossiakoff; Sachdev S. Sidhu
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Method validation and measurement of biomarkers in nonclinical and clinical samples in drug development: A conference report
Pharmaceutical Research, ISSN: 07248741
Jean W. Lee; Russell Weiner; Jeff M. Sailstad; Ronald Bowsher; Dean W. Knuth; Peter J. O'Brien; Jean L. Fourcroy; Rakesh Dixit; Lini Pandite; Robert G. Pietrusko; Holly D. Soares; Quarmby; Ole L. Vesterqvist; David M. Potter; James L. Witliff; Herbert A. Fritche; Timothy O'Leary; Lorah Perlee; Sunil Kadam; John A. Wagner
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Defining molecular targets for drug design: Synergism between academia and industry
Journal of Pediatric Gastroenterology and Nutrition, ISSN: 02772116
Andrew A. Chan
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Population pharmacokinetics or efalizumab (humanized monoclonal anti-CD11a antibody) following long-term subcutaneous weekly dosing in psoriasis subjects
Journal of Clinical Pharmacology, ISSN: 00912700
Sun; Jian-Feng Lu; Amita Joshi; Peter Compton; Paul Kwon; Rene Bruno
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Increased hepatobiliary clearance of unconjugated thyroxine determines DMP 904-induced alterations in thyroid hormone homeostasis in rats
Toxicological Sciences, ISSN: 10966080
Harvey Wong; Lois D. Lehman-McKeeman; Mary F. Grubb; Grossman; Vasanthi M. Bhaskaran; Eric G. Solon; Helen S. Shen; Ronald J. Gerson; Bruce D. Car; Bitao Zhao; Brian Gemzik
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