Genentech: Publications

July 1, 2004

Pharmacokinetic and pharmacodynamic characteristics of a long-acting Growth Hormone (GH) preparation (nutropin depot) in GH-deficient children

Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X

Stephen F. Kemp; Fielder; Kenneth M. Attie; Sandra L. Blethen; Edward O. Reiter; Kathleen M. Ford; Marian; Dao; Lee; Saenger

View on Scopus

July 1, 2004

The Risk Score Profile: A novel approach to characterising the risk of populations enrolled in clinical studies

European Heart Journal, ISSN: 0195668X

David A. Morrow; Elliott M. Antman; Sabina A. Murphy; Susan F. Assmann; Robert P. Giugliano; Christopher P. Cannon; C.Michael Gibson; Carolyn H. McCabe; Hal V. Barron; Frans Van De Werf; Eugene Braunwald

View on Scopus

July 1, 2004

Decrease in tumor apparent permeability-surface area product to a MRI macromolecular contrast medium following angiogenesis inhibition with correlations to cytotoxic drug accumulation

Microcirculation, ISSN: 10739688

Heike E. Daldrup-Link; Yoshitaka Okuhata; Allan Wolfe; Sudesk Srivastav; Sven Øie; Napoleone Ferrara; Robert L. Cohen; David M. Shames; Robert C. Brasch

View on Scopus

July 1, 2004

Relation of age and race with hospital death after acute myocardial infarction

American Heart Journal, ISSN: 00028703

Ajay Manhapra; John G. Canto; Viola Vaccarino; Lori Parsons; Calarina I. Kiefe; Hal V. Barron; William J. Rogers; W.Douglas Weaver; Steven Borzak

View on Scopus

July 1, 2004

Convergent recognition of the IgE binding site on the high-affinity IgE receptor

Structure, ISSN: 09692126

Jennifer Stamos; Eigenbrot; Nakamura; Mark E. Reynolds; Jianping Yin; Henry B. Lowman; Wayne J. Fairbrother; Melissa A. Starovasnik

View on Scopus

July 1, 2004

Modifications and intracellular trafficking of FADD/MORT1 and caspase-8 after stimulation of T lymphocytes

Cell Death and Differentiation, ISSN: 13509047

O'Reilly; Divisekera; Kim Newton; Scalzo; Kataoka; Puthalakath; Ito; David C.S. Huang; Andreas Strasser

View on Scopus

July 1, 2004

Clinical targeting of VEGF and EGFR effective in non-small cell lung cancer

Cancer Biology and Therapy, ISSN: 15384047 15558576

Roy S. Herbst; Eric Mininberg; Ted Henderson; Edward S. Kim; George R. Blumenschein; J. Jack J. Lee; Mylene Truong; Waun Hong; David H. Johnson; David Carbone; Ben Garcia; Dong Xie; Kelley

View on Scopus

June 30, 2004

Targeting interferon-α: A promising approach for systemic lupus erythematosus therapy

Lupus, ISSN: 09612033

Kerstin N. Schmidt; Wenjun Ouyang

View on Scopus

June 22, 2004

Vascular endothelial growth factor as a target for anticancer therapy

Oncologist, ISSN: 10837159

Napoleone Ferrara

View on Scopus

June 22, 2004

Circulating humoral factors and endothelial progenitor cells in patients with differing coronary collateral support

Circulation, ISSN: 00097322

Pier D. Lambiase; Richard J. Edwards; Prodromos Anthopoulos; Salman Rahman; Meng; Clifford A. Bucknall; Simon R. Redwood; Jeremy D. Pearson; Marber

View on Scopus

June 18, 2004

T-cell modulation for the treatment of chronic plaque psoriasis with efalizumab (Raptiva™): Mechanisms of action

Dermatology, ISSN: 10188665

Jullien; Prinz; Richard G. B. Langley; Ivor Caro; Wolfgang Dummer; Amita Joshi; Russell L Dedrick; Natta

View on Scopus

June 16, 2004

Crystal structure of the HGF β-chain in complex with the Sema domain of the Met receptor

EMBO Journal, ISSN: 02614189

Jennifer Stamos; Lazarus; Xiaoyi Yao; Daniel Kirchhofer; Wiesmann

View on Scopus

June 15, 2004

Cost-effectiveness of testing for hypercoagulability and effects on treatment strategies in patients with deep vein thrombosis

American Journal of Medicine, ISSN: 00029343

Andrew D. Auerbach; Gillian D. Sanders; Julie Hambleton

View on Scopus

June 15, 2004

Gene expression profiling for prognosis using Cox regression

Statistics in Medicine, ISSN: 02776715

Yudi Pawitan; Bjöhle; Wedren; Humphreys; Skoog; Huang; Lukas Amler; Shaw; Hall; Bergh

View on Scopus

June 15, 2004

Flex test: A fluorescent dextran test for UF membrane characterization

Journal of Membrane Science, ISSN: 03767388

Poonam Mulherkar; Robert Van Reis

View on Scopus

June 14, 2004

An industry survey on current practices in the design and analysis of active control studies

Journal of Biopharmaceutical Statistics, ISSN: 10543406

Christy Chuang-Stein; Corsee Sanders; Steve Snapinn

View on Scopus

June 11, 2004

AP-3-dependent mechanisms control the targeting of a chloride channel (ClC-3) in neuronal and non-neuronal cells

Journal of Biological Chemistry, ISSN: 00219258

Gloria Salazar; Rachal Love; Melanie L. Styers; Erica Werner; Andrew A. Peden; Sandra Rodriguez; Marla Gearing; Bruce H. Wainer; Victor Faundez

View on Scopus

June 4, 2004

Notch1-expressing cells are indispensable for prostatic branching morphogenesis during development and re-growth following castration and androgen replacement

Journal of Biological Chemistry, ISSN: 00219258

Xi-De Wang; Shou; Peter Wong; French; Gao

View on Scopus

June 3, 2004

Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer

New England Journal of Medicine, ISSN: 00284793

Herbert Hurwitz; Louis Fehrenbacher; Novotny; Thomas Cartwright; John Hainsworth; William Heim; Jordan Berlin; Ari Baron; Susan Griffing; Holmgren; Napoleone Ferrara; Gwendolyn Fyfe; Rogers; Robert Ross; Fairooz F. Kabbinavar

View on Scopus

June 1, 2004

Creation and characterization of a mouse model of mandibular distraction osteogenesis

Bone, ISSN: 87563282

Tony D. Fang; Randall P. Nacamuli; Hanjoon M. Song; Kenton D. Fong; Stephen M. Warren; Ali Salim; Richard A. D. Carano; Ellen H. Filvaroff; Michael T. Longaker

View on Scopus

June 1, 2004

Oxidative and osmotic stress signaling in tumor cells is mediated by ADAM proteases and heparin-binding epidermal growth factor

Molecular and Cellular Biology, ISSN: 02707306

Oliver M. Fischer; Stefan Hart; Andreas Gschwind; Norbert Prenzel; Axel Ullrich

View on Scopus

June 1, 2004

Acute metabolic acidosis: Characterization and diagnosis of the disorder and the plasma potassium response

Journal of the American Society of Nephrology, ISSN: 10466673

Jean-Martin Wiederseiner; Juergen Muser; Thomas Lutz; Henry N. Hulter; Reto Krapf

View on Scopus

June 1, 2004

A public gene trap resource for mouse functional genomics [1]

Nature Genetics, ISSN: 10614036

William C. Skarnes; Harald Von Melchner; Wolfgang Wurst; Geoff Hicks; Alex S. Nord; Tony Cox; Stephen G. Young; Patricia Ruiz; Phil Soriano; Marc Tessier-Lavigne; Bruce R. Conklin; William L. Stanford; Janet Rossant

View on Scopus

June 1, 2004

Fibroblast growth factor 19 increases metabolic rate and reverses dietary and leptin-deficient diabetes

Endocrinology, ISSN: 00137227

Ling Fu; Linu M. John; Adams; Yu; Elizabeth Tomlinson; Renz; P. Mickey Williams; Robert Soriano; Corpuz; Moffat; Richard L. Vandlen; Laura C. Simmons; Foster; Jean-Philippe Stephan; Siao Ping Tsai; Stewart

View on Scopus

May 25, 2004

Novel role for netrins in regulating epithelial behavior during lung branching morphogenesis

Current Biology, ISSN: 09609822

Yuru Liu; Elke Stein; Timothy Oliver; Yong Li; William J. Brunken; Manuel Koch; Marc Tessier-Lavigne; Brigid L.M. Hogan

View on Scopus

May 19, 2004

Pharmacy benefits and the use of drugs by the chronically ill

JAMA - Journal of the American Medical Association, ISSN: 00987484

Dana P. Goldman; Geoffrey F. Joyce; Jose J. Escarce; Jennifer E. Pace; Matthew D. Solomon; Marianne Laouri; Pamela B. Landsman; Steven M. Teutsch

View on Scopus

May 12, 2004

Identification of Wnt responsive genes using a murine mammary epithelial cell line model system

BMC Developmental Biology, ISSN: 1471213X

Lisa A. Taneyhill; Diane Pennica

View on Scopus

May 11, 2004

Thyrotropin-Releasing Hormone Is Induced in the Left Ventricle of Rats with Heart Failure and Can Provide Inotropic Support to the Failing Heart

Circulation, ISSN: 00097322

Hongkui Jin; Grazyna Fedorowicz; Renhui Yang; Annie Ogasawara; Franklin V. Peale Jr.; Thinh Q. Pham; Nicholas F. Paoni

View on Scopus

May 10, 2004

The Dorsolateral Corticospinal Tract in Mice: An Alternative Route for Corticospinal Input to Caudal Segments following Dorsal Column Lesions

Journal of Comparative Neurology, ISSN: 00219967

Oswald Steward; Binhai Zheng; Carole Ho; Kim Anderson; Marc Tessier-Lavigne

View on Scopus

May 6, 2004

The ubiquitin ligase COP1 is a critical negative regulator of p53

Nature, ISSN: 00280836

David Dornan; Ingrid E. Wertz; Harumi Shimizu; David Arnott; Gretchen D. Frantz; Patrick Dowd; Karen M. O'Rourke; Koeppen; Vishva M. Dixit

View on Scopus

May 4, 2004

Crystal structure of Clostridium botulinum neurotoxin protease in a product-bound state: Evidence for noncanonical zinc protease activity

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Brent Segelke; Mark Knapp; Saloumeh Kadkhodayan; Rod Balhorn; Bernhard Rupp

View on Scopus

May 3, 2004

N-Benzoyl amino acids as ICAM/LFA-1 inhibitors. Part 2: Structure-activity relationship of the benzoyl moiety

Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X

Burdick; James C. Marsters Jr.; Ignacio Aliagas; Mark S. Stanley; Beresini; Clark; Robert S. McDowell; Thomas Gadek

View on Scopus

May 1, 2004

VEGFA is necessary for chondrocyte survival during bone development

Development (Cambridge), ISSN: 09501991

Elazar Zelzer; Roni Mamluk; Napoleone Ferrara; Randall S. Johnson; Ernestina Schipani; Bjorn R. Olsen

View on Scopus

May 1, 2004

IL-22, a Th1 cytokine that targets the pancreas and select other peripheral tissues

International Immunopharmacology, ISSN: 15675769

Austin L. Gurney

View on Scopus

May 1, 2004

In the age of the biologics, is phototherapy obsolete?

Cosmetic Dermatology, ISSN: 10413766

John Y. Koo

View on Scopus

May 1, 2004

Absenteeism among employees with irritable bowel syndrome

Managed Care Interface, ISSN: 10965645

Christopher Zacker; Chawla; Shaohung Wang; Leigh Ann Albers

View on Scopus

May 1, 2004

Effects of simultaneous over-expression of Cu/ZnSOD and MnSOD on Drosophila melanogaster life span

Mechanisms of Ageing and Development, ISSN: 00476374

Jingtao Sun; John Molitor; John Tower

View on Scopus

May 1, 2004

Pulmonary Exacerbations in Cystic Fibrosis

Pediatric Pulmonology, ISSN: 87556863

Harvey R. Rabin; Butler; Mary Ellen Wohl; David E. Geller; Andrew A. Colin; Daniel V. Schidlow; Charles A. Johnson; Michael W. Konstan; Warren E. Regelmann

View on Scopus

May 1, 2004

Pathogenic roles of B cells in human autoimmunity: Insights from the clinic

Immunity, ISSN: 10747613

Flavius Martin; Andrew A. Chan

View on Scopus

May 1, 2004

Structure of the neural (N-) cadherin prodomain reveals a cadherin extracellular domain-like fold without adhesive characteristics

Structure, ISSN: 09692126

Alexander W. Koch; Amjad Farooq; Shan; Lei Zeng; David R. Colman; Ming-Ming Zhou

View on Scopus

May 1, 2004

Latent Membrane Protein 2A, a Viral B Cell Receptor Homologue, Induces CD5+ B-1 Cell Development

Journal of Immunology, ISSN: 00221767

Akiko Ikeda; Mark Merchant; Lori Lev; Richard Longnecker; Masato Ikeda

View on Scopus

May 1, 2004

SLIT2-Mediated ROBO2 signaling restricts kidney induction to a single site

Developmental Cell, ISSN: 15345807

Uta Grieshammer; Le Ma; Andrew Plump; Fan Wang; Marc Tessier-Lavigne; Gail R. Martin

View on Scopus

May 1, 2004

Expression of vascular endothelial growth factor, hypoxia inducible factor 1α, and carbonic anhydrase IX in human tumours

Journal of Clinical Pathology, ISSN: 00219746

Adrian M. Jubb; Thinh Q. Pham; Hanby; Gretchen D. Frantz; Franklin V. Peale Jr.; Thomas D Wu; Koeppen; Kenneth J. Hillan

View on Scopus

May 1, 2004

Pharmacokinetics of the antimalarial drug, AQ-13, in rats and cynomolgus macaques

International Journal of Toxicology, ISSN: 10915818 1092874X

Sandhya Ramanathan-Girish; Paul Catz; Moire R. Creek; Benjamin Wu; David Thomas; Donald J. Krogstad; Dibyendu De; Jon C. Mirsalis; Carol E. Green

View on Scopus

May 1, 2004

Rab14 Is Involved in Membrane Trafficking between the Golgi Complex and Endosomes

Molecular Biology of the Cell, ISSN: 10591524

Jagath R. Junutula; Ann De Mazière; Andrew A. Peden; Karen E. Ervin; Raj J. Advani; Suzanne Van Dijk; Judith Klumperman; Richard H. Scheller

View on Scopus

May 1, 2004

Growth Hormone (GH) Replacement Therapy in Adult-Onset GH Deficiency: Effects on Body Composition in Men and Women in a Double-Blind, Randomized, Placebo-Controlled Trial

Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X

Andrew R. Hoffman; Joyce Kuntze; Joyce Baptista; Howard B. A. Baum; Gerhard Baumann; Beverly M. K. Biller; Richard V. Clark; David Cook; Silvio E. Inzucchi; David Kleinberg; Anne Klibanski; Lawrence S. Phillips; E. Chester Ridgway; Richard J. Robbins; Janet Schlechte; Meeta Sharma; Michael O. Thorner; Mary Lee Vance

View on Scopus

May 1, 2004

Phage-display as a tool for quantifying protein stability determinants

European Journal of Biochemistry, ISSN: 00142956

Joanne D. Kotz; Christopher J. Bond; Andrea G Cochran

View on Scopus

May 1, 2004

Expression of Toll-Like Receptor 2 on CD16+ Blood Monocytes and Synovial Tissue Macrophages in Rheumatoid Arthritis

Arthritis and Rheumatism, ISSN: 00043591

Mitsuhiro Iwahashi; Masahiro Yamamura; Tetsushi Aita; Akira Okamoto; Akiko Ueno; Norio Ogawa; Sachiko Akashi; Kensuke Miyake; Godowski; Hirofumi Makino

View on Scopus

April 30, 2004

NTB-A, a New Activating Receptor in T Cells That Regulates Autoimmune Disease

Journal of Biological Chemistry, ISSN: 00219258

Patricia A. Valdez; Hua Wang; Dhaya Seshasayee; Menno Van Lookeren Campagne; Austin L. Gurney; Wyne P. Lee; Iqbal S. Grewal

View on Scopus

April 29, 2004

Rescue of NGF-deficient mice II: Basal forebrain cholinergic projections require NGF for target innervation but not guidance

Molecular Brain Research, ISSN: 0169328X

Phillips; Merry Nishimura; Armanini; Grace Chan; Albers; Davis

View on Scopus