Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 11051 - 11100 OF 15612 RESULTS

Mycobacterium marinum: The generalization and specialization of a pathogenic mycobacterium
Microbes and Infection, ISSN: 1769714X 12864579
Luisa M. Stamm; Eric J. Brown
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Quality Assurance Practices for Pharmaceutical Industry-Based Drug Information Departments: A Review and Case Study
Therapeutic Innovation and Regulatory Science, ISSN: 21684790
Stacey M. Fung; Joyce Serrano Martin
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Bevacizumab (Avastin).
Clinical journal of oncology nursing, ISSN: 10921095
Gena Middleton; Denise V Lapka
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Re: Catheter-directed Thrombolytic Therapy for Limb Ischemia: Current Status and Controversies [1]
Journal of Vascular and Interventional Radiology, ISSN: 10510443
Charles P. Semba; Iris Tam; Martha Blaney
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Topical vascular endothelial growth factor accelerates diabetic wound healing through increased angiogenesis and by mobilizing and recruiting bone marrow-derived cells
American Journal of Pathology, ISSN: 00029440
Robert D. Galiano; Oren M. Tepper; Catherine R. Pelo; Kirit A. Bhatt; Matthew Callaghan; Nicholas Bastidas; Bunting; Hope Steinmetz; Geoffrey C. Gurtner
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From functional genomics to target validation: The quest for better drugs
Drug Discovery Today: TARGETS, ISSN: 17418372
Jean-Philippe Stephan
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A blockade in Wnt signaling is activated following the differentiation of F9 teratocarcinoma cells
Experimental Cell Research, ISSN: 00144827
Sayumi Shibamoto; Jane Winer; Mickey P. Williams; Paul G. Polakis
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Discovery of novel PTP1b inhibitors
Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X
Denise A. Ockey; Thomas Gadek
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Bivalent antibody phage display mimics natural immunoglobulin
Journal of Immunological Methods, ISSN: 00221759
Chingwei V. Lee; Sachdev S. Sidhu; Fuh
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Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis
Nature Medicine, ISSN: 10788956
Scott T. Avecilla; Koichi Hattori; Beate Heissig; Rafael Tejada; Fang Liao; Koji Shido; David K. Jin; Sergio Dias; Fan Zhang; Travis E. Hartman; Neil R. Hackett; Crystal; Larry Witte; Daniel J. Hicklin; Peter Bohlen; Dan L. Eaton; David Lyden; Frederic J. De Sauvage; Shahin Rafii
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Neutralizing VEGF Bioactivity with a Soluble Chimeric VEGF-Receptor Protein flt(I-3) IgG Inhibits Testosterone-Stimulated Prostate Growth in Castrated Mice
Prostate, ISSN: 02704137
Ingela Franck Lissbrant; Peter Hammarsten; Erik Lissbrant; Napoleone Ferrara; Stina Häggström Rudolfsson; Anders Bergh
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Ureagenesis: Evidence for a lack of hepatic regulation of acid-base equilibrium in humans
American Journal of Physiology - Renal Physiology, ISSN: 03636127
Markus Hosch; Juergen Muser; Henry N. Hulter; Reto Krapf
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Maintaining change control in part 11 - Compliant systems - A quality systems approach
American Pharmaceutical Review, ISSN: 10998012
Peter Bland
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APC-Independent Activation of NK Cells by the Toll-Like Receptor 3 Agonist Double-Stranded RNA
Journal of Immunology, ISSN: 00221767
Kerstin N. Schmidt; Beatrice Leung; Mandy Kwong; Kol A. Zarember; Sanjeev Satyal; Tony A. Navas; Fay Wang; Godowski
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Design and baseline characteristics of The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study: A large cohort of patients with severe or difficult-to-treat asthma
Annals of Allergy, Asthma and Immunology, ISSN: 10811206
Chantal M. Dolan; Kyle Fraher; Eugene R. Bleecker; Larry Borish; Bradley E. Chipps; Mary Lou Hayden; Weiss; Zheng; Charles A. Johnson; Sally E. Wenzel
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Editorial introductions
Current Opinion in Nephrology and Hypertension, ISSN: 10624821
Barry M. Brenner; Marc R. Hammerman; Matthew R. Weir; Ronald C. Blantz; Pierre M. Ronco
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Single lead ST-segment recovery: A simple, reliable measure of successful fibrinolysis after acute myocardial infarction
American Heart Journal, ISSN: 00028703
Mushabbar A. Syed; Steven Borzak; Abed Asfour; Madhavi Gunda; Omar Obeidat; Sabina A. Murphy; Raymond J. Gibbons; Steven G. Gourlay; Hal V. Barron; W.Douglas Weaver; Michael Hudson
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Treatment of Pulmonary Arterial Hypertension with Sildenafil
Hospital Pharmacy, ISSN: 00185787
Stacey M. Fung; Mary J. Ferrill
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Impaired brain angiogenesis and neuronal apoptosis induced by conditional homozygous inactivation of vascular endothelial growth factor
Thrombosis and Haemostasis, ISSN: 03406245
Sabine Raab; Heike Beck; Andreas Gaumann; Ali Yüce; Hans-Peter Gerber; Karl Plate; Hans-Peter Hammes; Napoleone Ferrara; Georg Breier
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Reflections on Rice's formulae for level crossings - History, extensions and use
Australian and New Zealand Journal of Statistics, ISSN: 13691473
Leadbetter; Spaniolo
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Evaluation of procedures for amplification of small-size samples for hybridization on microarrays
Genomics, ISSN: 08887543
Sandra Klur; Toy; Mickey P. Williams; Ulrich Certa
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The HER receptor family: A rich target for therapeutic development
International Journal of Radiation Oncology Biology Physics, ISSN: 03603016
Robert Mass
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Quantification of Tumor Tissue Populations by Multispectral Analysis
Magnetic Resonance in Medicine, ISSN: 07403194
Richard A. D. Carano; Adrienne L. Ross; Ross; Simon P. Williams; Koeppen; Ralph H. Schwall; Nicholas Van Bruggen
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Substrate capacity consideration in developing kinase assays
Assay and Drug Development Technologies, ISSN: 1540658X
Laura DeForge; Andrea G. Cochan; Sherry Yeh; Brian S. Robinson; Karen L Billeci; Wai Lee T. Tong
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Raman Spectroscopic Characterization of Drying-Induced Structural Changes in a Therapeutic Antibody: Correlating Structural Changes with Long-Term Stability
Journal of Pharmaceutical Sciences, ISSN: 00223549
Samir Sane; Wong; Chung C. Hsu
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Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex
Cancer Cell, ISSN: 15356108
Matthew C Franklin; Kendall Carey; Vajdos; Daniel J. Leahy; De Vos; Mark X. Sliwkowski
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The discovery of receptor tyrosine kinases: Targets for cancer therapy
Nature Reviews Cancer, ISSN: 1474175X
Andreas Gschwind; Oliver M. Fischer; Axel Ullrich
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Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer
Nature Reviews Drug Discovery, ISSN: 14741776
Napoleone Ferrara; Kenneth J. Hillan; Hans-Peter Gerber; Novotny
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Hydrophobic vancomycin derivatives with improved ADME properties: Discovery of telavancin (TD-6424)
Journal of Antibiotics, ISSN: 00218820
Michael R. Leadbetter; Stacy M. Adams; Bettina Bazzini; Paul R. Fatheree; Dane E. Karr; Kevin M. Krause; Bernice M.T. Lam; Martin S. Linsell; Matthew B. Nodwell; John Pace; Kelly Quast; Jeng-Pyng Shaw; Elizabeth Soriano; Sean Trapp; Jenny D. Villena; Terry X. Wu; Burton G. Christensen; J. Kevin Judice
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EG-VEGF: A novel mediator of endocrine-specific angiogenesis, endothelial phenotype, and function
Annals of the New York Academy of Sciences, ISSN: 00778923
Jennifer Lecouter; Rui Lin; Napoleone Ferrara
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Recommendations for the design and optimization of immunoassays used in the detection of host antibodies against biotechnology products
Journal of Immunological Methods, ISSN: 00221759
Mire-Sluis; Yu Chen Barrett; Viswanath Devanarayan; Koren; Hank Liu; Mauricio Maia; Thomas Parish; George Scott; Gopi Shankar; Elizabeth Shores; Steven J. Swanson; Gary Taniguchi; Daniel Wierda; Linda A. Zuckerman
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Benzyl alcohol-induced destabilization of interferon-γ: A study by hydrogen-deuterium isotope exchange
Journal of Pharmaceutical Sciences, ISSN: 00223549
Scott A. Tobler; Bryan W. Holmes; Cromwell; Erik J. Fernandez
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Challenges in the development of high protein concentration formulations
Journal of Pharmaceutical Sciences, ISSN: 00223549
Steven J. Shire; Shahrokh; Jun Liu
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Thrombolysis for lower extremity deep venous thrombosis
Techniques in Vascular and Interventional Radiology, ISSN: 10892516
Charles P. Semba; Mahmood K Razavi; Stephen T. Kee; Daniel Y. Sze; Michael D. Dake
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Phage display-derived ligands provide structural insight into insulin-like growth factor I function
Spectroscopy, ISSN: 07124813
Nicholas J. Skelton; Schaffer; Deshayes; Tamas Blandl; Steven T. Runyon; Nakamura; Sachdev S. Sidhu
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The Sema domain of Met is necessary for receptor dimerization and activation
Cancer Cell, ISSN: 15356108
Monica Kong-Beltran; Jennifer Stamos; Dineli Wickramasinghe
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Neonatal hypoglycemia in a growth hormone registry: Incidence and pathogenesis
Journal of Pediatric Endocrinology and Metabolism, ISSN: 0334018X
Jennifer J. Bell; Gilbert P. August; Sandra L. Blethen; Joyce Baptista
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Targeting death receptors in cancer with Apo2L/TRAIL
Current Opinion in Pharmacology, ISSN: 14714892
Kelley; Avi Ashkenazi
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Structure-based models of cadherin-mediated cell adhesion: The evolution continues
Cellular and Molecular Life Sciences, ISSN: 1420682X
Alexander W. Koch; Manzur; Shan
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Bioprocess equipment: Characterization of energy dissipation rate and its potential to damage cells
Biotechnology Progress, ISSN: 87567938
Mike Mollet; Ningning Ma; Yang Zhao; Robert Brodkey; Ron Taticek; Jeffrey J. Chalmers
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WISP-1 is an osteoblastic regulator expressed during skeletal development and fracture repair
American Journal of Pathology, ISSN: 00029440
French; Raji J. Kaul; Aloma L. D'Souza; Crowley; Bao; Gretchen D. Frantz; Ellen H. Filvaroff; Luc Desnoyers
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Effects of omalizumab, a humanized monoclonal anti-IgE antibody, on nasal reactivity to allergen and local IgE synthesis
Annals of Allergy, Asthma and Immunology, ISSN: 10811206
Jonathan Corren; David Diaz-Sanchez; Andrew Saxon; Yamo Deniz; Reimann; Sinclair; Teresa Davancaze; Daniel C. Adelman
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Inhibitors of tissue factor•factor VIIa for anticoagulant therapy
Current Medicinal Chemistry, ISSN: 09298673
Lazarus; Alan G. Olivero; Eigenbrot; Daniel Kirchhofer
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Inhibitors of histone deacetylases promote hematopoietic stem cell self-renewal
Cytotherapy, ISSN: 14653249
Judy C. Young; Wu; Hansteen; Du; Sambucetti; Remiszewski; O'Farrell; Hill; Lavau; Lesley J. Murray
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Quantitative structure-pharmacokinetic parameters relationships (QSPKR) analysis of antimicrobial agents in humans using simulated annealing k-nearest-neighbor and partial least-square analysis methods
Journal of Pharmaceutical Sciences, ISSN: 00223549
Chee Ng; Yun-De Xiao; Wendy Putnam; Bert L. Lum; Alexander Tropsha
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Loss of HIF-1α in endothelial cells disrupts a hypoxia-driven VEGF autocrine loop necessary for tumorigenesis
Cancer Cell, ISSN: 15356108
Nan Tang; Lianchun Wang; Jeffrey Esko; Frank J. Giordano; Yan Huang; Hans-Peter Gerber; Napoleone Ferrara; Randall S. Johnson
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Quality assurance practices for pharmaceutical industry-based drug information departments: A review and case study
Drug Information Journal, ISSN: 00928615
Stacey M. Fung; Joyce Serrano Martin
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Effect of cardiac dysfunction of treatment outcomes in women receiving trastuzumab for HER2-overexpressing metastatic breast cancer
Clinical Breast Cancer, ISSN: 15268209
Debasish Tripathy; Andrew Seidman; Deborah Keefe; Clifford Hudis; Virginia Paton; Lieberman
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Quantification of bone lesions in rheumatoid arthritis by MRI multispectral tissue class transition analysis
Seminars in Musculoskeletal Radiology, ISSN: 1098898X 10897860
Richard A. D. Carano; John A. Lynch
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Ureagenesis: Evidence for a lack of hepatic regulation of acid-base equilibrium in humans
American Journal of Physiology - Renal Physiology, ISSN: 15221466 1931857X
Markus Hosch; Juergen Muser; Henry N. Hulter; Reto Krapf
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