Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 11151 - 11200 OF 15612 RESULTS

Emerging technologies that overcome biological barriers for therapeutic protein delivery
Expert Opinion on Biological Therapy, ISSN: 14712598
Daugherty; Mrsny
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Crystal structures of the benzene and ethanol solvates of neotame
Journal of Chemical Crystallography, ISSN: 10741542
Zedong Dong; Victor G. Young Jr.; Eric Munson; Steve A. Schroeder; Indra Prakash; David J. W. Grant
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Comprehensive mutagenesis of the C-terminal domain of the M13 gene-3 minor coat protein: The requirements for assembly into the bacteriophage particle
Journal of Molecular Biology, ISSN: 00222836
Gregory A. Weiss; Tomer A. Roth; Pierre F. Baldi; Sachdev S. Sidhu
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Tissue expression, protease specificity, and Kunitz domain functions of hepatocyte growth factor activator inhibitor-1B (HAI-1B), a new splice variant of HAI-1
Journal of Biological Chemistry, ISSN: 00219258
Daniel Kirchhofer; Peek; Wei Li; Jennifer Stamos; Eigenbrot; Saloumeh Kadkhodayan; J. Michael Elliott; Corpuz; Lazarus; Paul Moran
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Contributions of CDR3 to VHH domain stability and the design of monobody scaffolds for naive antibody libraries
Journal of Molecular Biology, ISSN: 00222836
Christopher J. Bond; James C. Marsters Jr.; Sachdev S. Sidhu
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The function role of GATA-3 in Th1 and Th2 differentiation
Immunologic Research, ISSN: 0257277X
Meixia Zhou; Wenjun Ouyang
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Plasmin activates the lymphangiogenic growth factors VEGF-C and VEGF-D
Journal of Experimental Medicine, ISSN: 00221007
Bradley K. McColl; Megan E. Baldwin; Sally Roufail; Craig Freeman; Robert L. Moritz; Pichard J. Simpson; Kari Alitalo; Steven A. Stacker; Marc G. Achen
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Genome-wide identification of chromosomal regions of increased tumor expression by transcriptome analysis
Cancer Research, ISSN: 00085472
Yan Zhou; Shiuh-Ming Luoh; Yan Zhang; Colin K. Watanabe; Thomas D Wu; Michael Ostland; William I. Wood; Zemin Zhang
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Prostaglandin E2 regulates cell migration via the intracellular activation of the epidermal growth factor receptor
Journal of Biological Chemistry, ISSN: 00219258
F. Gregory Buchanan; Dingzhi Wang; Francesca Bargiacchi; Raymond N. DuBois
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The functional binding epitope of a high affinity variant of human growth hormone mapped by shotgun alanine-scanning mutagenesis: Insights into the mechanisms responsible for improved affinity
Journal of Molecular Biology, ISSN: 00222836
Gábor Pál; Anthony A. Kossiakoff; Sachdev S. Sidhu
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Bacteriophage that display small molecules
Chemistry and Biology, ISSN: 10745521
Frederic A. Fellouse; Deshayes
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ABRF-PRG03: Phosphorylation site determination
Journal of Biomolecular Techniques, ISSN: 15240215 19434731
David Arnott; Mary Ann Gawinowicz; Raymond A. Grant; Thomas A. Neubert; Len C. Packman; Kaye D. Speicher; Kathryn Stone; Christoph W. Turck
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Superwarfarin and glass ingestion with prolonged coagulopathy requiring high-dose vitamin K1 therapy
Pharmacotherapy, ISSN: 02770008
Ben T. Tsutaoka; Michael Miller; Stacey M. Fung; Manish M. Patel; Kent R. Olson
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An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors
Molecular Cell, ISSN: 10972765
Antony W. Burgess; Hyun-Soo Cho; Eigenbrot; Kathryn M. Ferguson; Thomas P.J. Garrett; Daniel J. Leahy; Mark A. Lemmon; Mark X. Sliwkowski; Colin W. Ward; Shigeyuki Yokoyama
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Shedding light on bioscience. Symposium on optical imaging: Applications to biology and medicine
EMBO Reports, ISSN: 1469221X
Mary J. Cole; Melinda Pirity; Anna-Katerina Hadjantonakis
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Relation between hospital intra-aortic balloon counterpulsation volume and mortality in acute myocardial infarction complicated by cardiogenic shock
Circulation, ISSN: 00097322
Edmond W. Chen; John G. Canto; Lori Parsons; Eric D. Peterson; Katherine A. Littrell; Nathan R. Every; C.Michael Gibson; Judith S. Hochman; E. Magnus Ohman; Morris Cheeks; Hal V. Barron
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Photodetachment of hydrated oxalate dianions in the gas phase, C 2O42-(H2O)n (n-3-40): From solvated clusters to nanodroplet
Journal of Chemical Physics, ISSN: 00219606
Xue-Bin Wang; Xin Yang; John B. Nicholas; Lai-Sheng Wang
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Complex with a phage display-derived peptide provides insight into the function of insulin-like growth factor I
Biochemistry, ISSN: 00062960
Schaffer; Deshayes; Nakamura; Sachdev S. Sidhu; Nicholas J. Skelton
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Dynamics of cell surface molecules during T cell recognition
Annual Review of Biochemistry, ISSN: 00664154
Mark M. Davis; Michelle Krogsgaard; Johannes B. Huppa; Cenk Sumen; Marco A. Purbhoo; Darrell J. Irvine; Lawren C. Wu; Lauren Ehrlich
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The forkhead transcription factor FOXO4 induces the down-regulation of hypoxia-inducible factor 1α by a von Hippel-Lindau protein-independent mechanism
Journal of Biological Chemistry, ISSN: 00219258
Tracy Tzu-Ling Tang; Lasky
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Structural insight into how an anti-idiotypic antibody against D3H44 (anti-tissue factor antibody) restores normal coagulation
Journal of Molecular Biology, ISSN: 00222836
Eigenbrot; Meng; Rajeswari Krishnamurthy; Michael T. Lipari; Presta; Devaux; Wong; Paul Moran; Sherron L. Bullens; Daniel Kirchhofer
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The hypoxic response of tumors is dependent on their microenvironment
Cancer Cell, ISSN: 15356108
Barbara Blouw; Hanqiu Song; Tarik Tihan; Jenel Bosze; Napoleone Ferrara; Hans-Peter Gerber; Randall S. Johnson; Gabriele Bergers
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Comparison of neural network, Bayesian, and multiple stepwise regression-based limited sampling models to estimate area under the curve
Pharmacotherapy, ISSN: 02770008
Chee Ng
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Quantitative analysis of colorectal tissue microarrays by immunofluorescence and in situ hybridization
Journal of Pathology, ISSN: 00223417
Adrian M. Jubb; Landon; Jennifer Burwick; Thinh Q. Pham; Gretchen D. Frantz; Cairns; Philip Quirke; Franklin V. Peale Jr.; Kenneth J. Hillan
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Electron and excitation transfer in hetero-supramolecular assemblies and at molecule-nanoparticle interfaces
Pure and Applied Chemistry, ISSN: 00334545
Piotrowiak; Deshayes; Romanova; Cynthia Pagba; Sarmimala Hore; Giovanni Zordan; Ileana Place; Agnes Farrán
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The effects of an anti-CD11a mAb, efalizumab, on allergen-induced airway responses and airway inflammation in subjects with atopic asthma
Journal of Allergy and Clinical Immunology, ISSN: 00916749
Gauvreau; Allan B. Becker; Boulet; Jamila Chakir; Robert B. Fick Jr.; William L. Greene; Killian; O'Byrne; John K. Reid; Cockcroft
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Mice lacking the CARD of CARMA1 exhibit defective B lymphocyte development and impaired proliferation of their B and T lymphocytes
Current Biology, ISSN: 09609822
Kim Newton; Vishva M. Dixit
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Structure and function analysis of peptide antagonists of melanoma inhibitor of apoptosis (ML-IAP)
Biochemistry, ISSN: 00062960
Matthew C Franklin; Saloumeh Kadkhodayan; Heidi J. A. Wallweber; Daniela Alexandru; Mark D. Distefano; Linda O. Elliott; Flygare; Grace Mausisa; David C Okawa; Danny Ong; Domagoj Vucic; Deshayes; Wayne J. Fairbrother
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Trail/Apo2L
The Cytokine Handbook,
David H. Lynch; Avi Ashkenazi
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Early use of glycoprotein IIb/IIIa inhibitors in non-ST-elevation acute myocardial infarction: Observations from the national registry of myocardial infarction 4
Journal of the American College of Cardiology, ISSN: 07351097
Eric D. Peterson; Charles V. Pollack Jr.; Matthew T. Roe; Lori Parsons; Katherine A. Littrell; John G. Canto; Hal V. Barron
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Automated sample preparation using vapor-phase hydrolysis for amino acid analysis
Analytical Biochemistry, ISSN: 00032697
Alan Higbee; Susan C. Wong; William J. Henzel
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Production of the signalling molecule, autoinducer-2, by Neisseria meningitidis: Lack of evidence for a concerted transcriptional response
Microbiology, ISSN: 13500872
Joanne E. Dove; Kazutoyo Yasukawa; Colin R. Tinsley; Xavier Nassif
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Cooperation of cytokine signaling with chimeric transcription factors in leukemogenesis: PML-retinoic acid receptor alpha blocks growth factor-mediated differentiation
Molecular and Cellular Biology, ISSN: 02707306
Vernon T. Phan; David B. Shultz; Bao-Tran Truong; Timothy J. Blake; Anna L. Brown; Thomas J. Gonda; Michelle M. Le Beau; Scott C. Kogan
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Nrf1 is critical for redox balance and survival of liver cells during development
Molecular and Cellular Biology, ISSN: 02707306
Linyun Chen; Mandy Kwong; Ronghua Lu; David G. Ginzinger; Candy Lee; Laura Leung; Jefferson Y. Chan
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Comparison of the Escherichia coli proteomes for recombinant human growth hormone producing and nonproducing fermentations
Proteomics, ISSN: 16159853
Kathleen M. Champion; Julie C. Nishihara; Ilana S. Aldor; G. Tony Moreno; Dana C. Andersen; Kathy L. Stults; Vanderlaan
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Structural basis of the interaction between RalA and Sec5, a subunit of the sec6/8 complex
EMBO Journal, ISSN: 02614189
Shuya Fukai; Hugo T. Matern; Jagath R. Junutula; Richard H. Scheller; Axel T. Brünger
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Cooperation of cytokine signaling with chimeric transcription factors in leukemogenesis: PML-retinoic acid receptor alpha blocks growth factor-mediated differentiation
Molecular and Cellular Biology, ISSN: 02707306
Vernon T. Phan; David B. Shultz; Bao-Tran Truong; Timothy J. Blake; Anna L. Brown; Thomas J. Gonda; Michelle M. Le Beau; Scott Kogan
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Interstitial pneumonitis related to rituximab therapy [5] (multiple letters)
New England Journal of Medicine, ISSN: 00284793
Catherine Burton; Richard Kaczmarski; Riaz Jan-Mohamed; Benyunes; Pratik S. Multani; Andrew Saunders
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Neutropenia in patients treated with rituximab [6] (multiple letters)
New England Journal of Medicine, ISSN: 00284793
Eric Voog; Morschhauser; Philippe Solal-Celigny; Benyunes; Pratik S. Multani; Andrew Saunders
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Bolus inhalation of rhDNAse with the AERx system in subjects with cystic fibrosis
Journal of Aerosol Medicine: Deposition, Clearance, and Effects in the Lung, ISSN: 08942684
David E. Geller; John Thipphawong; Babatunde Otulana; Daniel Caplan; Dawn Ericson; Laura Milgram; Jerry Okikawa; Joanne M. Quan; C. Michael Bowman
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Role of VEGF-A in vascularization of pancreatic islets
Current Biology, ISSN: 09609822
Eckhard Lammert; Guoqiang Gu; Margaret McLaughlin; Dennis Brown; Rolf Brekken; Lewis Charles Murtaugh; Hans-Peter Gerber; Napoleone Ferrara; Douglas A. Melton
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Redesigning an antibody fragment for faster association with its antigen
Biochemistry, ISSN: 00062960
Jonathan S. Marvin; Henry B. Lowman
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Discovery of small molecule leads in a biotechnology datastream
Drug Discovery Today, ISSN: 13596446
Thomas Gadek; Robert S. McDowell
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Engineering exosite peptides for complete inhibition of factor VIIa using a protease switch with substrate phage
Journal of Biological Chemistry, ISSN: 00219258
Henry R. Maun; Eigenbrot; Lazarus
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A highly selective, non-hydantoin, non-carboxylic acid inhibitor of aldose reductase with potent oral activity in diabetic rat models: 6-(5-chloro-3-methylbenzofuran-2-sulfonyl)-2-H-pyridazin-3-one
Journal of Medicinal Chemistry, ISSN: 00222623
Mylari; Sandra J. Armento; Beebe; Edward L. Conn; Coutcher; Dina; Melissa T. O'Gorman; Michael C. Linhares; William H. Martin; Oates; David A. Tess; Gregory J. Withbroe; Zembrowski
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The magnitude of hedgehog signaling activity defines skin tumor phenotype
EMBO Journal, ISSN: 02614189
Vladimir Grachtchouk; Marina Grachtchouk; Lori Lowe; Tim Johnson; Lebing Wei; Aiqin Wang; Frederic J. De Sauvage; Andrzej A. Dlugosz
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Pathogenesis of mucous cell metaplasia in a murine asthma model
American Journal of Pathology, ISSN: 00029440
J. Rachel Reader; Tepper; Edward S. Schelegle; Melinda C. Aldrich; Lei F. Putney; Juergen W. Pfeiffer; Dallas M. Hyde
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Differential expression of the angiogenic factor genes vascular endothelial growth factor (VEGF) and endocrine gland-derived VEGF in normal and polycystic human ovaries
American Journal of Pathology, ISSN: 00029440
Napoleone Ferrara; Gretchen D. Frantz; Jennifer Lecouter; Lisa Dillard-Telm; Thinh Q. Pham; Aparna Draksharapu; Thomas Giordano; Franklin V. Peale Jr.
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The biology of VEGF and its receptors
Nature Medicine, ISSN: 10788956
Napoleone Ferrara; Hans-Peter Gerber; Jennifer Lecouter
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Strategies and methods in the identification of antagonists of protein-protein interactions
BioTechniques, ISSN: 07366205
Thomas Gadek
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