Genentech: Publications

June 30, 2004

Targeting interferon-α: A promising approach for systemic lupus erythematosus therapy

Lupus, ISSN: 09612033

Kerstin N. Schmidt; Wenjun Ouyang

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June 22, 2004

Vascular endothelial growth factor as a target for anticancer therapy

Oncologist, ISSN: 10837159

Napoleone Ferrara

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June 22, 2004

Circulating humoral factors and endothelial progenitor cells in patients with differing coronary collateral support

Circulation, ISSN: 00097322

Pier D. Lambiase; Richard J. Edwards; Prodromos Anthopoulos; Salman Rahman; Meng; Clifford A. Bucknall; Simon R. Redwood; Jeremy D. Pearson; Marber

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June 18, 2004

T-cell modulation for the treatment of chronic plaque psoriasis with efalizumab (Raptiva™): Mechanisms of action

Dermatology, ISSN: 10188665

Jullien; Prinz; Richard G. B. Langley; Ivor Caro; Wolfgang Dummer; Amita Joshi; Russell L Dedrick; Natta

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June 16, 2004

Crystal structure of the HGF β-chain in complex with the Sema domain of the Met receptor

EMBO Journal, ISSN: 02614189

Jennifer Stamos; Lazarus; Xiaoyi Yao; Daniel Kirchhofer; Wiesmann

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June 15, 2004

Cost-effectiveness of testing for hypercoagulability and effects on treatment strategies in patients with deep vein thrombosis

American Journal of Medicine, ISSN: 00029343

Andrew D. Auerbach; Gillian D. Sanders; Julie Hambleton

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June 15, 2004

Gene expression profiling for prognosis using Cox regression

Statistics in Medicine, ISSN: 02776715

Yudi Pawitan; Bjöhle; Wedren; Humphreys; Skoog; Huang; Lukas Amler; Shaw; Hall; Bergh

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June 15, 2004

Flex test: A fluorescent dextran test for UF membrane characterization

Journal of Membrane Science, ISSN: 03767388

Poonam Mulherkar; Robert Van Reis

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June 14, 2004

An industry survey on current practices in the design and analysis of active control studies

Journal of Biopharmaceutical Statistics, ISSN: 10543406

Christy Chuang-Stein; Corsee Sanders; Steve Snapinn

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June 11, 2004

AP-3-dependent mechanisms control the targeting of a chloride channel (ClC-3) in neuronal and non-neuronal cells

Journal of Biological Chemistry, ISSN: 00219258

Gloria Salazar; Rachal Love; Melanie L. Styers; Erica Werner; Andrew A. Peden; Sandra Rodriguez; Marla Gearing; Bruce H. Wainer; Victor Faundez

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June 4, 2004

Notch1-expressing cells are indispensable for prostatic branching morphogenesis during development and re-growth following castration and androgen replacement

Journal of Biological Chemistry, ISSN: 00219258

Xi-De Wang; Shou; Peter Wong; French; Gao

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June 3, 2004

Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer

New England Journal of Medicine, ISSN: 00284793

Herbert Hurwitz; Louis Fehrenbacher; Novotny; Thomas Cartwright; John Hainsworth; William Heim; Jordan Berlin; Ari Baron; Susan Griffing; Holmgren; Napoleone Ferrara; Gwendolyn Fyfe; Rogers; Robert Ross; Fairooz F. Kabbinavar

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June 1, 2004

Creation and characterization of a mouse model of mandibular distraction osteogenesis

Bone, ISSN: 87563282

Tony D. Fang; Randall P. Nacamuli; Hanjoon M. Song; Kenton D. Fong; Stephen M. Warren; Ali Salim; Richard A. D. Carano; Ellen H. Filvaroff; Michael T. Longaker

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June 1, 2004

Oxidative and osmotic stress signaling in tumor cells is mediated by ADAM proteases and heparin-binding epidermal growth factor

Molecular and Cellular Biology, ISSN: 02707306

Oliver M. Fischer; Stefan Hart; Andreas Gschwind; Norbert Prenzel; Axel Ullrich

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June 1, 2004

Acute metabolic acidosis: Characterization and diagnosis of the disorder and the plasma potassium response

Journal of the American Society of Nephrology, ISSN: 10466673

Jean-Martin Wiederseiner; Juergen Muser; Thomas Lutz; Henry N. Hulter; Reto Krapf

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June 1, 2004

A public gene trap resource for mouse functional genomics [1]

Nature Genetics, ISSN: 10614036

William C. Skarnes; Harald Von Melchner; Wolfgang Wurst; Geoff Hicks; Alex S. Nord; Tony Cox; Stephen G. Young; Patricia Ruiz; Phil Soriano; Marc Tessier-Lavigne; Bruce R. Conklin; William L. Stanford; Janet Rossant

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June 1, 2004

Fibroblast growth factor 19 increases metabolic rate and reverses dietary and leptin-deficient diabetes

Endocrinology, ISSN: 00137227

Ling Fu; Linu M. John; Adams; Yu; Elizabeth Tomlinson; Renz; P. Mickey Williams; Robert Soriano; Corpuz; Moffat; Richard L. Vandlen; Laura C. Simmons; Foster; Jean-Philippe Stephan; Siao Ping Tsai; Stewart

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May 25, 2004

Novel role for netrins in regulating epithelial behavior during lung branching morphogenesis

Current Biology, ISSN: 09609822

Yuru Liu; Elke Stein; Timothy Oliver; Yong Li; William J. Brunken; Manuel Koch; Marc Tessier-Lavigne; Brigid L.M. Hogan

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May 19, 2004

Pharmacy benefits and the use of drugs by the chronically ill

JAMA - Journal of the American Medical Association, ISSN: 00987484

Dana P. Goldman; Geoffrey F. Joyce; Jose J. Escarce; Jennifer E. Pace; Matthew D. Solomon; Marianne Laouri; Pamela B. Landsman; Steven M. Teutsch

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May 12, 2004

Identification of Wnt responsive genes using a murine mammary epithelial cell line model system

BMC Developmental Biology, ISSN: 1471213X

Lisa A. Taneyhill; Diane Pennica

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May 11, 2004

Thyrotropin-Releasing Hormone Is Induced in the Left Ventricle of Rats with Heart Failure and Can Provide Inotropic Support to the Failing Heart

Circulation, ISSN: 00097322

Hongkui Jin; Grazyna Fedorowicz; Renhui Yang; Annie Ogasawara; Franklin V. Peale Jr.; Thinh Q. Pham; Nicholas F. Paoni

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May 10, 2004

The Dorsolateral Corticospinal Tract in Mice: An Alternative Route for Corticospinal Input to Caudal Segments following Dorsal Column Lesions

Journal of Comparative Neurology, ISSN: 00219967

Oswald Steward; Binhai Zheng; Carole Ho; Kim Anderson; Marc Tessier-Lavigne

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May 6, 2004

The ubiquitin ligase COP1 is a critical negative regulator of p53

Nature, ISSN: 00280836

David Dornan; Ingrid E. Wertz; Harumi Shimizu; David Arnott; Gretchen D. Frantz; Patrick Dowd; Karen M. O'Rourke; Koeppen; Vishva M. Dixit

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May 4, 2004

Crystal structure of Clostridium botulinum neurotoxin protease in a product-bound state: Evidence for noncanonical zinc protease activity

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Brent Segelke; Mark Knapp; Saloumeh Kadkhodayan; Rod Balhorn; Bernhard Rupp

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May 3, 2004

N-Benzoyl amino acids as ICAM/LFA-1 inhibitors. Part 2: Structure-activity relationship of the benzoyl moiety

Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X

Burdick; James C. Marsters Jr.; Ignacio Aliagas; Mark S. Stanley; Beresini; Clark; Robert S. McDowell; Thomas Gadek

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May 1, 2004

VEGFA is necessary for chondrocyte survival during bone development

Development (Cambridge), ISSN: 09501991

Elazar Zelzer; Roni Mamluk; Napoleone Ferrara; Randall S. Johnson; Ernestina Schipani; Bjorn R. Olsen

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May 1, 2004

IL-22, a Th1 cytokine that targets the pancreas and select other peripheral tissues

International Immunopharmacology, ISSN: 15675769

Austin L. Gurney

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May 1, 2004

In the age of the biologics, is phototherapy obsolete?

Cosmetic Dermatology, ISSN: 10413766

John Y. Koo

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May 1, 2004

Absenteeism among employees with irritable bowel syndrome

Managed Care Interface, ISSN: 10965645

Christopher Zacker; Chawla; Shaohung Wang; Leigh Ann Albers

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May 1, 2004

Effects of simultaneous over-expression of Cu/ZnSOD and MnSOD on Drosophila melanogaster life span

Mechanisms of Ageing and Development, ISSN: 00476374

Jingtao Sun; John Molitor; John Tower

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May 1, 2004

Pulmonary Exacerbations in Cystic Fibrosis

Pediatric Pulmonology, ISSN: 87556863

Harvey R. Rabin; Butler; Mary Ellen Wohl; David E. Geller; Andrew A. Colin; Daniel V. Schidlow; Charles A. Johnson; Michael W. Konstan; Warren E. Regelmann

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May 1, 2004

Pathogenic roles of B cells in human autoimmunity: Insights from the clinic

Immunity, ISSN: 10747613

Flavius Martin; Andrew A. Chan

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May 1, 2004

Structure of the neural (N-) cadherin prodomain reveals a cadherin extracellular domain-like fold without adhesive characteristics

Structure, ISSN: 09692126

Alexander W. Koch; Amjad Farooq; Shan; Lei Zeng; David R. Colman; Ming-Ming Zhou

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May 1, 2004

Latent Membrane Protein 2A, a Viral B Cell Receptor Homologue, Induces CD5+ B-1 Cell Development

Journal of Immunology, ISSN: 00221767

Akiko Ikeda; Mark Merchant; Lori Lev; Richard Longnecker; Masato Ikeda

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May 1, 2004

SLIT2-Mediated ROBO2 signaling restricts kidney induction to a single site

Developmental Cell, ISSN: 15345807

Uta Grieshammer; Le Ma; Andrew Plump; Fan Wang; Marc Tessier-Lavigne; Gail R. Martin

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May 1, 2004

Expression of vascular endothelial growth factor, hypoxia inducible factor 1α, and carbonic anhydrase IX in human tumours

Journal of Clinical Pathology, ISSN: 00219746

Adrian M. Jubb; Thinh Q. Pham; Hanby; Gretchen D. Frantz; Franklin V. Peale Jr.; Thomas D Wu; Koeppen; Kenneth J. Hillan

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May 1, 2004

Pharmacokinetics of the antimalarial drug, AQ-13, in rats and cynomolgus macaques

International Journal of Toxicology, ISSN: 10915818 1092874X

Sandhya Ramanathan-Girish; Paul Catz; Moire R. Creek; Benjamin Wu; David Thomas; Donald J. Krogstad; Dibyendu De; Jon C. Mirsalis; Carol E. Green

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May 1, 2004

Rab14 Is Involved in Membrane Trafficking between the Golgi Complex and Endosomes

Molecular Biology of the Cell, ISSN: 10591524

Jagath R. Junutula; Ann De Mazière; Andrew A. Peden; Karen E. Ervin; Raj J. Advani; Suzanne Van Dijk; Judith Klumperman; Richard H. Scheller

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May 1, 2004

Growth Hormone (GH) Replacement Therapy in Adult-Onset GH Deficiency: Effects on Body Composition in Men and Women in a Double-Blind, Randomized, Placebo-Controlled Trial

Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X

Andrew R. Hoffman; Joyce Kuntze; Joyce Baptista; Howard B. A. Baum; Gerhard Baumann; Beverly M. K. Biller; Richard V. Clark; David Cook; Silvio E. Inzucchi; David Kleinberg; Anne Klibanski; Lawrence S. Phillips; E. Chester Ridgway; Richard J. Robbins; Janet Schlechte; Meeta Sharma; Michael O. Thorner; Mary Lee Vance

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May 1, 2004

Phage-display as a tool for quantifying protein stability determinants

European Journal of Biochemistry, ISSN: 00142956

Joanne D. Kotz; Christopher J. Bond; Andrea G Cochran

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May 1, 2004

Expression of Toll-Like Receptor 2 on CD16+ Blood Monocytes and Synovial Tissue Macrophages in Rheumatoid Arthritis

Arthritis and Rheumatism, ISSN: 00043591

Mitsuhiro Iwahashi; Masahiro Yamamura; Tetsushi Aita; Akira Okamoto; Akiko Ueno; Norio Ogawa; Sachiko Akashi; Kensuke Miyake; Godowski; Hirofumi Makino

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April 30, 2004

NTB-A, a New Activating Receptor in T Cells That Regulates Autoimmune Disease

Journal of Biological Chemistry, ISSN: 00219258

Patricia A. Valdez; Hua Wang; Dhaya Seshasayee; Menno Van Lookeren Campagne; Austin L. Gurney; Wyne P. Lee; Iqbal S. Grewal

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April 29, 2004

Rescue of NGF-deficient mice II: Basal forebrain cholinergic projections require NGF for target innervation but not guidance

Molecular Brain Research, ISSN: 0169328X

Phillips; Merry Nishimura; Armanini; Grace Chan; Albers; Davis

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April 23, 2004

Phage-displayed antibody libraries of synthetic heavy chain complementarity determining regions

Journal of Molecular Biology, ISSN: 00222836

Sachdev S. Sidhu; Bing Li; Chen; Frederic A. Fellouse; Eigenbrot; Fuh

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April 16, 2004

MALT1/Paracaspase Is a Signaling Component Downstream of CARMA1 and Mediates T Cell Receptor-induced NF-κB Activation

Journal of Biological Chemistry, ISSN: 00219258

Tuanjie Che; Yun You; Donghai Wang; Matthew J. Tanner; Vishva M. Dixit; Xin Lin

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April 16, 2004

Engineering an APRIL-specific B Cell Maturation Antigen

Journal of Biological Chemistry, ISSN: 00219258

Darshana Patel; Heidi J. A. Wallweber; Jianping Yin; Stephanie K. Shriver; Scot A. Marsters; Nathaniel C. Gordon; Melissa A. Starovasnik; Robert F. Kelley

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April 15, 2004

The endothelial-cell-derived secreted factor Egfl7 regulates vascular tube formation

Nature, ISSN: 00280836

Leon Parker; Maike Schmidt; Suk-Won Jin; Gray; Dimitris Beis; Thinh Q. Pham; Gretchen D. Frantz; Susan Palmieri; Kenneth J. Hillan; Didier Y. R. Stainier; Frederic J. De Sauvage; Weilan Ye

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April 8, 2004

Neoplastic Complications of HIV Infection

AIDS and Other Manifestations of HIV Infection,

Paula O'Connor; David T. Scadden

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April 1, 2004

Syntaxin-6 SNARE Involvement in Secretory and Endocytic Pathways of Cultured Pancreatic β-Cells

Molecular Biology of the Cell, ISSN: 10591524

Regina Kuliawat; Elena Kalinina; Jason Bock; Lloyd Fricker; Timothy E. McGraw; Se Ryoung Kim; Jiayu Zhong; Richard H. Scheller; Peter Arvan

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April 1, 2004