Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 11401 - 11450 OF 15612 RESULTS

Psoriasis as a model for T-cell-mediated disease: Immunobiologic and clinical effects of treatment with multiple doses of efalizumab, an anti-CD11a antibody
Archives of Dermatology, ISSN: 0003987X
Alice Gottlieb; James G. Krueger; Knut Wittkowski; Russell L Dedrick; Patricia Walicke; Marvin Garovoy
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Expression of full-length immunoglobulins in Escherichia coli: Rapid and efficient production of aglycosylated antibodies
Journal of Immunological Methods, ISSN: 00221759
Laura C. Simmons; Dorothea Reilly; Laura Klimowski; T. Shantha Raju; Meng; Paul Sims; Kyu Hong; Robert L. Shields; Lisa A. Damico; Rancatore; Yansura
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The forkhead transcription factor AFX activates apoptosis by induction of the BCL-6 transcriptional repressor
Journal of Biological Chemistry, ISSN: 00219258
Tracy Tzu-Ling Tang; Dowbenko; Amanda Jackson; Lisa Toney; Lewin; Alexander Dent; Lasky
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Increases in free, unbound insulin-like growth factor I enhance insulin responsiveness in human hepatoma G2 cells in culture
Journal of Biological Chemistry, ISSN: 00219258
Keiji Sakai; Henry B. Lowman; David R. Clemmons
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Synergistic induction of tumor antigens by Wnt-1 signaling and retinoic acid revealed by gene expression profiling
Journal of Biological Chemistry, ISSN: 00219258
David A. Tice; Szeto; Soloviev; Bonnee Rubinfeld; Fong; Dugger; Jane Winer; Mickey Williams; David Wieand; Victoria Smith; Ralph H. Schwall; Diane Pennica; Paul G. Polakis
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On the variability of covariate adjustment: Experience with Koch's method for evaluating the absolute difference in proportions in randomized clinical trials
Controlled Clinical Trials, ISSN: 01972456
Emmanuel Lesaffre; Kris Bogaerts; Xin Li; Bluhmki
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Fusion of two distinct peptide exosite inhibitors of Factor VIIa
Biochemical Journal, ISSN: 02646021
Roberge; Peek; Daniel Kirchhofer; Dennis; Lazarus
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The Erbin PDZ domain binds with high affinity and specificity to the carboxyl termini of δ-catenin and ARVCF
Journal of Biological Chemistry, ISSN: 00219258
Richard Laura; Andrea S. Witt; Heike A. Held; Gerstner; Deshayes; Michael F. T. Koehler; Kenneth S. Kosik; Sachdev S. Sidhu; Lasky
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Cardiotrophin-1 (CT-1) can protect the adult heart from injury when added both prior to ischaemia and at reperfusion
Cardiovascular Research, ISSN: 00086363
Zhihong Liao; Bhawanjit K. Brar; Qing Cai; Anastatis Stephanou; O'Leary; Diane Pennica; Derek M Yellon; David S. Latchman
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Lavage and nipple aspiration of breast ductal fluids: A source of biomarkers for environmental mutagenesis
Environmental and Molecular Mutagenesis, ISSN: 08936692
Pam Klein; Julia A. Lawrence
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Exaggerated hypotensive effect of vascular endothelial growth factor in spontaneously hypertensive rats
Hypertension, ISSN: 0194911X
Renhui Yang; Annie Ogasawara; Zioncheck; Zhen Ren; Guo-Wei He; Geralyn G. Deguzman; Nicolas Pelletier; Shen; Bunting; Hongkui Jin
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A dominant-negative p65 PAK peptide inhibits angiogenesis
Circulation Research, ISSN: 00097330
William B. Kiosses; John Hood; Suya Yang; Mary E. Gerritsen; David A. Cheresh; Nazilla Alderson; Martin Alexander Schwartz
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SMAC negatively regulates the anti-apoptotic activity of melanoma inhibitor of apoptosis (ML-IAP)
Journal of Biological Chemistry, ISSN: 00219258
Domagoj Vucic; Deshayes; Heidi J. A. Wallweber; Pisabarro; Saloumeh Kadkhodayan; Wayne J. Fairbrother; Vishva M. Dixit
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Biotransformation reactions of five-membered aromatic heterocyclic rings
Chemical Research in Toxicology, ISSN: 0893228X
Deepak Dalvie; Amit S. Kalgutkar; S. Cyrus Khojasteh; R. Scott Obach; John O'Donnell
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Recombinant protein expression for therapeutic applications
Current Opinion in Biotechnology, ISSN: 09581669
Dana C. Andersen; Lynne Krummen
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Progress in understanding the structure-activity relationships of P-glycoprotein
Advanced Drug Delivery Reviews, ISSN: 0169409X
Terry R Stouch; Gudmundsson
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AKT/PKB phosphorylation of p21Cip/WAF1 enhances protein stability of p21Cip/WAF1 and promotes cell survival
Journal of Biological Chemistry, ISSN: 00219258
Ying Li; Dowbenko; Lasky
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Inhibitors of protein-protein interactions
Expert Opinion on Therapeutic Patents, ISSN: 13543776
Denise A. Ockey; Thomas Gadek
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A human antibody that inhibits factor IX/IXa function potently inhibits arterial thrombosis without increasing bleeding
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN: 10795642
Refino; Surinc Er Jeet; Leo Deguzman; Bunting; Daniel Kirchhofer
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Identification of a novel homotypic interaction motif required for the phosphorylation of receptor-interacting protein (RIP) by RIP3
Journal of Biological Chemistry, ISSN: 00219258
Xiaoqing Sun; Jianping Yin; Melissa A. Starovasnik; Wayne J. Fairbrother; Vishva M. Dixit
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Characterization of endocrine gland-derived vascular endothelial growth factor signaling in adrenal cortex capillary endothelial cells
Journal of Biological Chemistry, ISSN: 00219258
Rui Lin; Jennifer Lecouter; Joe Kowalski; Napoleone Ferrara
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Methylbenzene chemistry on zeolite HBeta: Multiple insights into methanol-to-olefin catalysis
Journal of Physical Chemistry B, ISSN: 10895647
Alain Sassi; Mark A. Wildman; Hee Jung Ahn; Paritosh Prasad; John B. Nicholas; James F. Haw
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1H, 13C, and 15N resonance assignment of the vascular endothelial growth factor receptor-binding domain in complex with a receptor-blocking peptide [5]
Journal of Biomolecular NMR, ISSN: 09252738
Borlan Pan; Wayne J. Fairbrother
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Expression profiling of a human cell line model of prostatic cancer reveals a direct involvement of interferon signaling in prostate tumor progression
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Shou; Robert Soriano; Simon W. Hayward; Gerald R. Cunha; P. Mickey Williams; Gao
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Chemometric evaluation of on-line high-pressure liquid chromatography in mammalian cell cultures: Analysis of amino acids and glucose
Biotechnology and Bioengineering, ISSN: 00063592
Tina M. Larson; Martin Gawlitzek; Heather Evans; Urs Albers; Cacia
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Microcirculation down under
Trends in Pharmacological Sciences, ISSN: 01656147
Tailoi Chan-Ling; Mary E. Gerritsen; Caryl E Hill; Paul Kubes; Michael Perry
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Cardiac dysfunction in the trastuzumab clinical trials experience
Journal of Clinical Oncology, ISSN: 0732183X
Andrew Seidman; Clifford Hudis; Mary Kathryn Pierri; Steven Shak; Virginia Paton; Ashby; Maureen Murphy; Stanford J. Stewart; Deborah Keefe
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Activation of the Wnt pathway interferes with serum response element-driven transcription of immediate early genes
Journal of Biological Chemistry, ISSN: 00219258
David A. Tice; Soloviev; Paul G. Polakis
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Bacterial toxins as tools for mucosal vaccination
Drug Discovery Today, ISSN: 13596446
Mrsny; Daugherty; Marian McKee; David FitzGerald
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Vascular endothelial-junctional adhesion molecule (VE-JAM)/JAM 2 interacts with T, NK, and dendritic cells through JAM 3
Journal of Immunology, ISSN: 00221767
Tony W. Liang; Chiu; Austin L. Gurney; Aiko Sidle; Daniel B. Tumas; Peter Schow; Foster; Toni Klassen; Kathryn Dennis; Richard A. Demarco; Thinh Q. Pham; Gretchen D. Frantz; Sherman Fong
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The core membrane fusion complex governs the probability of synaptic vesicle fusion but not transmitter release kinetics
Journal of Neuroscience, ISSN: 02706474
Finley; Sejal M. Patel; Daniel V. Madison; Richard H. Scheller
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Vascular endothelial-junctional adhesion molecule (VE-JAM)/JAM 2 interacts with T, NK, and dendritic cells through JAM 3
Journal of Immunology, ISSN: 00221767
Tony W. Liang; Chiu; Austin L. Gurney; Aiko Sidle; Daniel B. Tumas; Peter Schow; Foster; Toni Klassen; Kathryn Dennis; Richard A. Demarco; Thinh Q. Pham; Gretchen D. Frantz; Fong
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Cold elicits the simultaneous induction of fatty acid synthesis and β-oxidation in murine brown adipose tissue: Prediction from differential gene expression and confirmation in vivo
FASEB Journal, ISSN: 08926638
Xing Xian; Lewin; William F. Forrest; Adams
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Generation of an LFA-1 antagonist by the transfer of the ICAM-1 immunoregulatory epitope to a small molecule
Science, ISSN: 00368075
Thomas Gadek; Burdick; Robert S. McDowell; Mark S. Stanley; James C. Marsters Jr.; Kenneth J. Paris; David A. Oare; Mark E. Reynolds; Ladner; Kimberly Zioncheck; Wyne P. Lee; Gribling; Dennis; Nicholas J. Skelton; Daniel B. Tumas; Clark; Keating; Beresini; Tilley; Presta; Bodary
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Nitrogen assimilation and growth of wheat under elevated carbon dioxide
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Arnold J. Bloom; David R. Smart; Duy T. Nguyen; Peter S. Searles
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Surface-tension-confined microfluidics
Langmuir, ISSN: 07437463
Philippe Lam; Kenneth J. Wynne; Gary E. Wnek
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Stable "zeta" peptides that act as potent antagonists of the high-affinity IgE receptor
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Nakamura; Mark E. Reynolds; Chen; Melissa A. Starovasnik; Henry B. Lowman
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Host defense functions of proteolytically processed and parent (unprocessed) cathelicidins of rabbit granulocytes
Infection and Immunity, ISSN: 00199567
Kol A. Zarember; Seth S. Katz; Brian F. Tack; Laurence Doukhan; Weiss; Elsbach
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PSTPIP is a substrate of PTP-PEST and serves as a scaffold guiding PTP-PEST toward a specific dephosphorylation of WASP
Journal of Biological Chemistry, ISSN: 00219258
Jean-François Côté; Ping Lin Chung; Jean-François Théberge; Maxime Hallé; Spencer; Lasky; Michel L. Tremblay
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IL-17: Prototype member of an emerging cytokine family
Journal of Leukocyte Biology, ISSN: 07415400
Aggarwal; Austin L. Gurney
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New insight into how tissue factor allosterically regulates Factor VIIa
Trends in Cardiovascular Medicine, ISSN: 10501738
Eigenbrot; Daniel Kirchhofer
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Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines
Journal of Immunology, ISSN: 00221767
Kol A. Zarember; Godowski
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Photodetachment and theoretical study of free and water-solvated nitrate anions, NO3-(H2O)n (n=0-6)
Journal of Chemical Physics, ISSN: 00219606
Xue-Bin Wang; Xin Yang; Lai-Sheng Wang; John B. Nicholas
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MRI measurement of cerebral water diffusion and its application to experimental research
Biomedical Imaging in Experimental Neuroscience,
Richard A. D. Carano; Nicholas Van Bruggen; De Crespigny
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Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth
Cancer Cell, ISSN: 15356108
David B. Agus; Robert W. Akita; Fox; Gail D. Lewis; Higgins; Paul Pisacane; Julie A. Lofgren; Charles Tindell; Douglas P. Evans; Maiese; Scher; Mark X. Sliwkowski
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Inconsistencies in reporting the occurrence and timing of first intercourse among adolescents
Journal of Sex Research, ISSN: 00224499
Dawn M. Upchurch; Lee A. Lillard; Carol S. Aneshensel; Nicole F. Li
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Phase I study of the combination of losoxantrone and cyclophosphamide in patients with refractory solid tumours
British Journal of Cancer, ISSN: 00070920
Goh; Vokes; Amita Joshi; Ratain
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Rituximab: Ongoing and future clinical development
Seminars in Oncology, ISSN: 00937754
Grillo-Lopez; Eric Hedrick; Michelle Rashford; Benyunes
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Gene expression profiling in silico: Relative expression of candidate angiogenesis associated genes in renal cell carcinomas
Experimental Nephrology, ISSN: 10187782
Mary E. Gerritsen; Franklin V. Peale Jr.; Thomas D Wu
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Rantes, a monocyte and T lymphocyte chemotactic cytokine releases histamine from human basophils
Journal of Immunology, ISSN: 00221767
Piotr Kuna; Sesha R. Reddigari; Thomas J. Schall; Doreen Rucinski; Michael Y. Viksman; Allen P. Kaplan
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