Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 11451 - 11500 OF 15612 RESULTS

A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease
Gastroenterology, ISSN: 00165085
Yevgeny Zolotarevsky; Athanasia Koutsouris; Deborah E. Gonzalez; Quan; Jeffrey Tom; Mrsny; Jerrold R. Turner
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Evaluation of total IGF-I assay methods using samples from Type I and Type II diabetic patients
Journal of Immunological Methods, ISSN: 00221759
Chestnut; Quarmby
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Oncogenic human papillomavirus E6 proteins target the MAGI-2 and MAGI-3 proteins for degradation
Oncogene, ISSN: 09509232
Miranda Thomas; Richard Laura; Karin Hepner; Ernesto Guccione; Charles L. Sawyers; Lasky; Lawrence Banks
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Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth
Cancer Cell, ISSN: 15356108
Agus; Robert W. Akita; Fox; Gail D. Lewis; Higgins; Paul Pisacane; Julie A. Lofgren; Charles Tindell; Douglas P. Evans; Maiese; Scher; Mark X. Sliwkowski
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In silico data filtering to identify new angiogenesis targets from a large in vitro gene profiling data set
Physiological Genomics, ISSN: 15312267
Mary E. Gerritsen; Robert Soriano; Suya Yang; Gladys S. Ingle; Constance Zlot; Toy; Jane Winer; Aparna Draksharapu; Franklin V. Peale Jr.; Thomas D Wu; P. Mickey Williams
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Tumor-cell resistance to death receptor-induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax
Nature Medicine, ISSN: 10788956
Heidi LeBlanc; David Lawrence; Eugene Varfolomeev; Klara Totpal; John Morlan; Peter Schow; Fong; Ralph H. Schwall; Sinicropi; Avi Ashkenazi
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Safety and efficacy of alteplase for restoring function in occluded central venous catheters: Results of the cardiovascular thrombolytic to open occluded lines trial
Journal of Clinical Oncology, ISSN: 0732183X
Steven R. Deitcher; Mark R Fesen; Paul M Kiproff; Hill; Xin Li; Edward R. McCluskey; Charles P. Semba
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EG-VEGF and the concept of tissue-specific angiogenic growth factors
Seminars in Cell and Developmental Biology, ISSN: 10849521
Jennifer Lecouter; Napoleone Ferrara
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Production information management
Pharmaceutical Technology, ISSN: 01478087
Hans Koning-Bastiaan
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Validation of large-scale chromatographic processes, Part 1: Case study of neuleze capture on Macroprep High-S
BioPharm, ISSN: 10408304
Timothy N. Breece; Ellen Gilkerson; Charles H. Schmelzer
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Enhancing the anticoagulant potency of soluble tissue factor mutants by increasing their affinity to factor VIIa
Thrombosis and Haemostasis, ISSN: 03406245
Yang; Geoffrey F. Lee; Markus A. Riederer; Robert F. Kelley
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The importance of freezing on lyophilization cycle development
BioPharm, ISSN: 10408304
Thomas W. Patapoff; David E. Overcashier
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Hippocampal dysfunction and behavioral deficit in the water maze in mice: An unresolved issue?
Brain Research Bulletin, ISSN: 03619230
Gerlai; Alexander McNamara; Simon P. Williams; Phillips
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A real-time quantitative PCR-based method for the detection and quantification of xenotropic Murine Leukemia Virus (X-MuLV) and its application in evaluation of X-MuLV removal during pharmaceutical protein purification
Process in Safety Science and Technology Part B,
Shi; Qi Chen; Lenore A Norling; Allen S.L. Lau; Sherrie Krejci; Yuan Xu
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Evaluation of a quantitative product-enhanced reverse transcriptase assay to monitor retrovirus in mAb cell-culture
Biologicals, ISSN: 10451056
Kurt Brorson; Yuan Xu; Patrick Swann; Elizabeth Hamilton; Mehnaz Mustafa; Christina De Wit; Lenore A Norling; Kathryn Stein
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Selective detection of membrane proteins without antibodies: a mass spectrometric version of the Western blot.
Molecular and Cellular Proteomics, ISSN: 15359476
David Arnott; Kishiyama; Luis; Sarah Ludlum; James C. Marsters Jr.; Stults
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Acute ischemic syndromes: Adjunctive therapy
Cardiology Clinics, ISSN: 07338651
Katherine A. Littrell; Karl B. Kern
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Large-scale analysis of gene expression profiles.
Briefings in bioinformatics, ISSN: 14675463
Thomas D Wu
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VEGF-A has a critical, nonredundant role in angiogenic switching and pancreatic β cell carcinogenesis
Cancer Cell, ISSN: 15356108
Masahiro Inoue; Jeffrey H. Hager; Napoleone Ferrara; Hans-Peter Gerber; Douglas Hanahan
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Identification of a novel death domain-containing adaptor molecule for ectodysplasin-A receptor that is mutated in crinkled mice
Current Biology, ISSN: 09609822
Minhong Yan; Zemin Zhang; John B.B. Ridgway; Sarah Schilbach; Wayne J. Fairbrother; Vishva M. Dixit
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Rituximab in combination with CHOP or fludarabine in low-grade lymphoma
Seminars in Oncology, ISSN: 00937754
Myron S. Czuczman; Alexandra Fallon; Mohr; Stewart; Bernstein; McCarthy; Skipper; Brown; Kena Miller; Diane Wentling; Klippenstein; Loud; Mike K Rock; Benyunes; Grillo-Lopez; Bernstein
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The association of sex and payer status on management and subsequent survival in acute myocardial infarction
Archives of Internal Medicine, ISSN: 00039926
John G. Canto; William J. Rogers; Nisha C. Chandra; William J. French; Hal V. Barron; Paul D. Frederick; Charles Maynard|; Nathan R. Every
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Dynamic contrast-enhanced magnetic resonance imaging as a surrogate marker of tumor response to anti-angiogenic therapy in a xenograft model of glioblastoma multiforme
Journal of Magnetic Resonance Imaging, ISSN: 10531807
Axel Gossmann; Thomas H. Helbich; Nagato Kuriyama; Ostrowitzki; Timothy P.L. Roberts; David M. Shames; Nicholas Van Bruggen; Michael F. Wendland; Mark A. Israel; Robert C. Brasch
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Effect of growth hormone therapy on height in children with idiopathic short stature: A meta-analysis
Archives of Pediatrics and Adolescent Medicine, ISSN: 10724710
Beth S. Finkelstein; Thomas F. Imperiale; Theodore Speroff; Ursula Marrero; Deborah J. Radcliffe; Leona Cuttler
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Prevention of experimental choroidal neovascularization with intravitreal anti-vascular endothelial growth factor antibody fragment
Archives of Ophthalmology, ISSN: 00039950
Magdalena G. Krzystolik; Mehran A. Afshari; Anthony P. Adamis; Jacques Gaudreault; Evangelos S. Gragoudas; Norman Michaud; Wenjun Li; Edward Connolly; Charles A. O'Neill; Joan W. Miller
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Pharmacokinetics of rhuMAb CD18, a recombinant humanised monoclonal antibody fragment to CD18, in normal healthy human volunteers
BioDrugs, ISSN: 11738804
David E. Allison; Steven G. Gourlay; Koren; Miller; Judy Fox
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Transgenic mice expressing human fibroblast growth factor-19 display increased metabolic rate and decreased adiposity
Endocrinology, ISSN: 00137227
Elizabeth Tomlinson; Ling Fu; Linu M. John; Hultgren; Huang; Renz; Jean-Philippe Stephan; Siao Ping Tsai; Powell-Braxton; French; Stewart
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Targeting death and decoy receptors of the tumour-necrosis factor superfamily
Nature Reviews Cancer, ISSN: 1474175X
Avi Ashkenazi
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Vesicle budding from endoplasmic reticulum
Methods in Enzymology, ISSN: 00766879
Yuval Shimoni; Randy Schekman
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Characterization and implications of bioassay variation.
Developments in Biologicals, ISSN: 14246074
Michael Ostland
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Selected topics in parallel line bioassay.
Developments in Biologicals, ISSN: 14246074
Giltinan
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Surface adsorption of recombinant human interferon-γ in lyophilized and spray-lyophilized formulations
Journal of Pharmaceutical Sciences, ISSN: 00223549
Serena D. Webb; Stephen L. Golledge; Cleland; John F. Carpenter; Theodore W. Randolph
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Semisolid, self-catalyzed poly(ortho ester)s as controlled-release systems: Protein release and protein stability issues
Journal of Pharmaceutical Sciences, ISSN: 00223549
Marco De Van Weert; Marinus J. Van Steenbergen; Cleland; Jorge Heller; Wim E. Hennink; Daan J. A. Crommelin
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Increased expression of cardiotrophin-1 during ventricular remodeling in hypertensive rats
American Journal of Physiology - Heart and Circulatory Physiology, ISSN: 03636135
Yoshihito Takimoto; Takeshi Aoyama; Yoshitaka Iwanaga; Toshiaki Izumi; Yasuki Kihara; Diane Pennica; Shigetake Sasayama
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VEGF regulates remodeling during permanent anatomic closure of the ductus arteriosus
American Journal of Physiology - Regulatory Integrative and Comparative Physiology, ISSN: 03636119
Ronald I. Clyman; Steven R. Seidner; Hiroki Kajino; Christine Roman; Cameron J. Koch; Napoleone Ferrara; Nahid Waleh; Françoise Mauray; Yao Qi Chen; Elizabeth A. Perkett; Timothy Quinn
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A mouse model of hepatocellular carcinoma: Ectopic expression of fibroblast growth factor 19 in skeletal muscle of transgenic mice
American Journal of Pathology, ISSN: 00029440
Nicholes; Guillet; Elizabeth Tomlinson; Kenneth J. Hillan; Wright; Gretchen D. Frantz; Thinh Q. Pham; Lisa Dillard-Telm; Siao Ping Tsai; Jean-Philippe Stephan; Stinson; Stewart; French
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Comprehensive functional maps of the antigen-binding site of an anti-ErbB2 antibody obtained with shotgun scanning mutagenesis
Journal of Molecular Biology, ISSN: 00222836
Vajdos; Adams; Timothy N. Breece; Presta; De Vos; Sachdev S. Sidhu
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Structure of a phage display-derived variant of human growth hormone complexed to two copies of the extracellular domain of its receptor: Evidence for strong structural coupling between receptor binding sites
Journal of Molecular Biology, ISSN: 00222836
Celia A. Schiffer; Ultsch; Scott Walsh; Somers; De Vos; Anthony A. Kossiakoff
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Amino acid determinants of β-hairpin conformation in erythropoeitin receptor agonist peptides derived from a phage display library
Journal of Molecular Biology, ISSN: 00222836
Nicholas J. Skelton; Russell; Frederic J. De Sauvage; Andrea G Cochran
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Solution structure of a phage-derived peptide antagonist in complex with vascular endothelial growth factor
Journal of Molecular Biology, ISSN: 00222836
Borlan Pan; Bing Li; Russell; Jeffrey Tom; Andrea G Cochran; Wayne J. Fairbrother
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Expression of transgene encoded TGF-β in islets prevents autoimmune diabetes in NOD mice by a local mechanism
Journal of Autoimmunity, ISSN: 08968411
Iqbal S. Grewal; Kate D. Grewal; F. Susan Wong; Hua Wang; Dominic E. Picarella; Charles A. Janeway Jr.; Richard A. Flavell
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Epigenetic changes in tumor Fas levels determine immune escape and response to therapy
Cancer Cell, ISSN: 15356108
Heather Maecker; Zhong Yun; Holden T. Maecker; Amato J. Giaccia
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Effects of early treatment with growth hormone on infarct size, survival, and cardiac gene expression after acute myocardial infarction
Growth Hormone and IGF Research, ISSN: 10966374
Hongkui Jin; Renhui Yang; Hsienwie Lu; Annie Ogasawara; Wei Li; Anne Ryan; Franklin V. Peale Jr.; Nicholas F. Paoni
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Can a small-molecular gadolinium contrast agent be applied successfully with dynamic MRI to quantitatively define brain tumor microvascular responses to angiogenesis inhibition?
Academic Radiology, ISSN: 10766332
Robert C. Brasch; Axel Gossmann; Thomas H. Helbich; Nagato Kuriyama; Timothy P.L. Roberts; David M. Shames; Nicholas Van Bruggen; Michael F. Wendland; Mark A. Israel
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Measuring patients' trust in their primary care providers
Medical Care Research and Review, ISSN: 10775587
Mark A. Hall; Zheng; Elizabeth Dugan; Fabian Camacho; Kristin E. Kidd; Aneil Mishra; Rajesh Balkrishnan
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A slow release formulation of insulin as a treatment for osteoarthritis
Osteoarthritis and Cartilage, ISSN: 10634584
Liping Cai; Okumu; Cleland; Beresini; Deborah A. Hogue; Lin; Ellen H. Filvaroff
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Inhospital outcome of acute myocardial infarction in patients with prior coronary artery bypass surgery
American Heart Journal, ISSN: 00028703
Verghese Mathew; Bernard Gersh; Hal V. Barron; Nathan R. Every; Alan J. Tiefenbrunn; Paul D. Frederick; Judith A. Malmgren
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Development of a frozen cell array as a high-throughput approach for cell-based analysis
American Journal of Pathology, ISSN: 00029440
Jean-Philippe Stephan; Silvia Schanz; Anne Wong; Peter Schow; Wai Lee T. Wong
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Cardiotrophin-1 and urocortin cause protection by the same pathway and hypertrophy via distinct pathways in cardiac myocytes
Cytokine, ISSN: 10434666
Julia Railson; Zhihong Liao; Bhawanjit K. Brar; Joanna C. Buddle; Diane Pennica; Anastatis Stephanou; David S. Latchman
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MAGI-1: A widely expressed, alternatively spliced tight junction protein
Experimental Cell Research, ISSN: 00144827
Richard Laura; Ross; Koeppen; Lasky
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