Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 11501 - 11550 OF 15612 RESULTS

January 1, 2002

Sequence plasticity in the antigen-binding site of a therapeutic anti-Her2 antibody

Journal of Molecular Biology, ISSN: 00222836

Gerstner; Paul J. Carter; Henry B. Lowman

January 1, 2002

A minimized M13 coat protein defines the requirements for assembly into the bacteriophage particle

Journal of Molecular Biology, ISSN: 00222836

Tomer A. Roth; Gregory A. Weiss; Eigenbrot; Sachdev S. Sidhu

January 1, 2002

In vivo regulation of plasminogen function by plasma carboxypeptidase B

Journal of Clinical Investigation, ISSN: 00219738

Carmen M. Swaisgood; Schmitt; Dan L. Eaton; Edward F. Plow

January 1, 2002

From characterization of antibodies to prediction of immunogenicity.

Developments in Biologicals, ISSN: 14246074

Koren

January 1, 2002

Regulation of Apo2L/tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in thyroid carcinoma cells

American Journal of Pathology, ISSN: 00029440

Vassiliki Poulaki; Constantine S. Mitsiades; Vassiliki Kotoula; Sophia Tseleni-Balafouta; Avi Ashkenazi; Demetrios A. Koutras; Nicholas Mitsiades

January 1, 2002

Challenges with current technology for the detection, measurement and characterization of antibodies against biological therapeutics.

Developments in Biologicals, ISSN: 14246074

Mire-Sluis

January 1, 2002

Detection of minute virus of mice using real time quantitative PCR in assessment of virus clearance during the purification of mammalian cell substrate derived biotherapeutics

Biologicals, ISSN: 10451056

Dejin Zhan; Margaret Roy; Christine Valera; Jesse Cardenas; Vennari; Janice W. Chen; Shengjiang Liu

January 1, 2002

The product development continuum: the evolution and application of the concept of comparability.

Developments in Biologicals, ISSN: 14246074

Robert L. Garnick

January 1, 2002

Role of vascular endothelial growth factor in physiologic and pathologic angiogenesis: therapeutic implications.

Seminars in Oncology, ISSN: 00937754

Napoleone Ferrara

January 1, 2002

Quantifying β-sheet stability by phage display

Journal of Molecular Biology, ISSN: 00222836

Mark D. Distefano; Zhong; Andrea G Cochran

January 1, 2002

Analysis of Smoothened as a candidate gene for human holoprosencephaly

Gene Function and Disease, ISSN: 14387506

Jeffrey E. Ming; Bennie Jeng; Frederic J. De Sauvage; Maximilian Muenke

January 1, 2002

The use of an animal immunogenicity model in the development of Protropin somatrem (methionyl human growth hormone).

Developments in Biologicals, ISSN: 14246074

Andrew J.S. Jones

January 1, 2002

The role of EG-VEGF in the regulation of angiogenesis in endocrine glands

Cold Spring Harbor Symposia on Quantitative Biology, ISSN: 00917451

Jennifer Lecouter; Rui Lin; Napoleone Ferrara

December 28, 2001

The Di-leucine Motif of Vesicle-associated Membrane Protein 4 Is Required for Its Localization and AP-1 Binding

Journal of Biological Chemistry, ISSN: 00219258

Andrew A. Peden; Grace Y. Park; Richard H. Scheller

December 27, 2001

Recent advances in DNA sequencing by capillary and microdevice electrophoresis

Electrophoresis, ISSN: 01730835

Luba Mitnik; Mark Novotny; Chantal Felten; Scott Buonocore; Lance Koutny; Dieter Schmalzing

December 24, 2001

Distinct regulators control the expression of the mid-hindbrain organizer signal FGF8

Nature Neuroscience, ISSN: 10976256

Weilan Ye; Maxime Bouchard; Donna Stone; Xiaodong Liu; Francis Vella; James Lee; Harukazu Nakamura; Siew-Lan Ang; Meinrad Busslinger; Rosenthal

December 19, 2001

Effect of omalizumab on symptoms of seasonal allergic rhinitis: A randomized controlled trial

JAMA - Journal of the American Medical Association, ISSN: 00987484

Thomas B. Casale; John Condemi; Craig LaForce; Anjuli Nayak; Michael Rowe; Marc Watrous; Margaret McAlary; Angel Fowler-Taylor; Amy Racine; Niroo Gupta; Robert B. Fick Jr.; Giovanni Della Cioppa

December 14, 2001

WISP-1 Binds to Decorin and Biglycan

Journal of Biological Chemistry, ISSN: 00219258

Luc Desnoyers; David Arnott; Diane Pennica

December 10, 2001

Attenuation of HIF-1 DNA-binding activity limits hypoxia-inducible endothelin-1 expression

Pflugers Archiv European Journal of Physiology, ISSN: 00316768

Camenisch; Stroka; Gassmann; Wenger

December 7, 2001

Death Receptor Recruitment of Endogenous Caspase-10 and Apoptosis Initiation in the Absence of Caspase-8

Journal of Biological Chemistry, ISSN: 00219258

Frank C. Kischkel; David Lawrence; Antoine Tinel; Heidi LeBlanc; Arvind Virmani; Peter Schow; Adi Gazdar; John Blenis; David Arnott; Avi Ashkenazi

December 5, 2001

Oxygen saturation and heart rate in healthy school children and adolescents living at high altitude

American Journal of Human Biology, ISSN: 10420533

Huicho; Pawson; León-Velarde; Rivera-Ch; Pacheco; Muro; Silva

December 4, 2001

The ionic layer is required for efficient dissociation of the SNARE complex by α-SNAP and NSF

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Suzie J. Scales; Bryan Y. Yoo; Richard H. Scheller

December 4, 2001

Double-blind, randomized trial of an anti-CD18 antibody in conjunction with recombinant tissue plasminogen activator for acute myocardial infarction limitation of myocardial infarction following thrombolysis in acute myocardial infarction (LIMIT AMI) study

Circulation, ISSN: 00097322

Kenneth W. Baran; Michel Nguyen; George McKendall; Costas Lambrew; Gary Dykstra; Sebastian T. Palmeri; Raymond J. Gibbons; Steven Borzak; Burton E. Sobel; Steven G. Gourlay; Amy Chen Rundle; C.Michael Gibson; Hal V. Barron

December 1, 2001

Spatial expression patterns of peptide transporters in the human and rat gastrointestinal tracts, caco-2 in vitro cell culture model, and multiple human tissues

AAPS Journal, ISSN: 15507416

Dea Herrera-Ruiz; Wang; Thomas J. Cook; Gregory T. Knipp; Gudmundsson; Smith; Teresa N. Faria

December 1, 2001

Impaired water maze learning performance without altered dopaminergic function in mice heterozygous for the GDNF mutation

European Journal of Neuroscience, ISSN: 0953816X

Gerlai; Alexander McNamara; Choi-Lundberg; Armanini; Ross; Powell-Braxton; Phillips

December 1, 2001

A mechanism-based pharmacokinetic/pharmacodynamic (PK/PD) model for omalizumab (rhuMAb-E25)

Clinical Pharmacology and Therapeutics, ISSN: 00099236

Sun; Marian; Schoenhoff; Sinclair; Pick

December 1, 2001

Incidence and predictors of bleeding events after fibrinolytic therapy with fibrin-specific agents: A comparison of TNK-tPA and rt-PA

European Heart Journal, ISSN: 0195668X

Frans Van De Werf; Hal V. Barron; Paul W. Armstrong; Christopher B. Granger; Berioli; Barbash; Pehrsson; Verheugt; Meyer; Betriu; Robert M. Califf; Xin Li; Fox

December 1, 2001

Acinar cells of the pancreas are a target of interleukin-22

Journal of Interferon and Cytokine Research, ISSN: 10799907

Aggarwal; Xie; Maruoka; Foster; Austin L. Gurney

December 1, 2001

Safety of the weight-adjusted dosing regimen of tenecteplase in the ASSENT-trial

American Journal of Cardiology, ISSN: 00029149

Brad G. Angeja; John H. Alexander; Richard Chin; Xin Li; Hal V. Barron; Paul W. Armstrong; Christopher B. Granger; Frans Van De Werf; C.Michael Gibson

December 1, 2001

The role of vascular endothelial growth factor in angiogenesis

Acta Haematologica, ISSN: 00015792

Napoleone Ferrara; Hans-Peter Gerber

December 1, 2001

Automated Differential Pressure Calibrations Below 3 in. H 2O

Proceedings of the International Instrumentation Symposium,

Steve Ward; Brian Bailey

December 1, 2001

Protein-protein interfaces: Mimics and inhibitors

Current Opinion in Chemical Biology, ISSN: 13675931

Andrea G Cochran

December 1, 2001

Endothelial expression of vascular cell adhesion molecule-1 correlates with metastatic pattern in spontaneous melanoma

Microcirculation, ISSN: 10739688

Robert R. Langley; Ricarda Carlisle; Li Ma; Robert D. Specian; Mary E. Gerritsen; D. Neil Granger

December 1, 2001

Bioinformatics in the post-genomic era

Trends in Biotechnology, ISSN: 01677799

Thomas D Wu

December 1, 2001

Pharmacokinetics and pharmacodynamics of MuM17, a surrogate antibody for rhumaab CD11A

Clinical Pharmacology and Therapeutics, ISSN: 00099236

Carla Washington; Howell; Zuckerman; Tran; John Lowe; Mortesen; Fielder; Judy Fox; Janet Clarke

December 1, 2001

Forced expression of murine IL-17E induces growth retardation, jaundice, a Th2-biased response, and multiorgan inflammation in mice

Journal of Immunology, ISSN: 00221767

Pan; French; Mao; Maruoka; Risser; James Lee; Foster; Aggarwal; Nicholes; Guillet; Peter Schow; Austin L. Gurney

December 1, 2001

A phase II trial of humanized anti-vascular endothelial growth factor antibody for the treatment of androgen-independent prostate cancer

Prostate Journal, ISSN: 10955100

Reese; Fratesi; Corry; Novotny; Holmgren; Small

December 1, 2001

Expanded bed adsorption in the purification of monoclonal antibodies: A comparison of process alternatives

Bioseparation, ISSN: 0923179X

Gregory S. Blank; Gerardo Zapata; Fahrner; Milton; Yedinak; Knudsen; Charles H. Schmelzer

November 19, 2001

Impaired c-Jun amino terminal kinase activity and T cell differentiation in death receptor 6-deficient mice

Journal of Experimental Medicine, ISSN: 00221007

Haoran Zhao; Minhong Yan; Hua Wang; Sharon Erickson; Iqbal S. Grewal; Vishva M. Dixit

November 15, 2001

The association between white blood cell count and acute myocardial infarction mortality in patients ≥65 years of age: Findings from the cooperative cardiovascular project

Journal of the American College of Cardiology, ISSN: 07351097

Hal V. Barron; Steven D. Harr; Martha J. Radford; Yongfei Wang; Harlan M. Krumholz

November 15, 2001

First-line herceptin® monotherapy in metastatic breast cancer

Oncology, ISSN: 00302414

Charles L. Vogel; Melody A. Cobleigh; Debasish Tripathy; John C. Gutheil; Lyndsay N. Harris; Louis Fehrenbacher; Dennis J. Slamon; Maureen Murphy; Novotny; Michael Burchmore; Steven Shak; Stanford J. Stewart

November 15, 2001

Cardiovascular effects of carbon monoxide and cigarette smoking

Journal of the American College of Cardiology, ISSN: 07351097

Shoshana Zevin; Sandra Saunders; Steven G. Gourlay; Peyton Jacob III; Neal L. Benowitz

November 12, 2001

Additional transporter characterization may lead to new pharmaceutical opportunities

Pharmaceutical Research, ISSN: 07248741

Gudmundsson

November 7, 2001

Triplet excitation transfer through the walls of hemicarcerands: Dependence of the electronic coupling on the size of the molecular cage

Journal of the American Chemical Society, ISSN: 00027863

Romanova; Deshayes; Piotrowiak

November 7, 2001

CT-1 mediated cardioprotection against ischaemic re-oxygenation injury is mediated by PI3 kinase, Akt and MEK1/2 pathways

Cytokine, ISSN: 10434666

Bhawanjit K. Brar; Anastatis Stephanou; Diane Pennica; David S. Latchman

November 7, 2001

Adapting pharmacokinetic properties of a humanized anti-interleukin-8 antibody for therapeutic applications using site-specific pegylation

Cytokine, ISSN: 10434666

Leong; Laura DeForge; Presta; Gonzalez; Audrey Fan; Marcel Reichert; Anan Chuntharapai; Jin Kim; Daniel B. Tumas; Wyne P. Lee; Gribling; Snedecor; Han Chen; Vanessa Hsei; Schoenhoff; Victoria Hale; James Deveney; Iphigenia Koumenis; Shahrokh; McKay; Walter Galan; Brian Wagner; Narindray; Hébert; Gerardo Zapata

November 2, 2001

Crystal Structure and Biophysical Properties of a Complex between the N-terminal SNARE Region of SNAP25 and Syntaxin 1a

Journal of Biological Chemistry, ISSN: 00219258

Kira M. S. Misura; Lino C. Gonzalez Jr.; Andrew P. May; Richard H. Scheller; William I. Weis

November 2, 2001

Fusion without SNAREs?

Science, ISSN: 00368075

Suzie J. Scales; Finley; Richard H. Scheller

November 1, 2001

Factor recruitment and TIF2/GRIP1 corepressor activity at a collagenase-3 response element that mediates regulation by phorbol esters and hormones

EMBO Journal, ISSN: 02614189

Inez Rogatsky; Kol A. Zarember; Keith R. Yamamoto

November 1, 2001

Newer antidepressants for hot flashes

Contemporary Ob-Gyn, ISSN: 00903159

Charles L. Loprinzi; Debra L. Barton; Deborah J. Rhodes; Dietlind L. Wahner-Roedler

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