Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 11551 - 11600 OF 15612 RESULTS

November 1, 2001

Hormone therapy and the risk of stroke after acute myocardial infarction in postmenopausal women

Journal of the American College of Cardiology, ISSN: 07351097

Brad G. Angeja; Michael G. Shlipak; Alan S. Go; Johnston; Paul D. Frederick; John G. Canto; Hal V. Barron; Deborah Grady

October 31, 2001

Crystallization kinetics of ampicillin

Industrial and Engineering Chemistry Research, ISSN: 08885885

Ottens; Lebreton; Zomerdijk; Rijkers; Bruinsma; Van Der Wielen

October 31, 2001

Expression profiling techniques for cardiac molecular phenotyping

Trends in Cardiovascular Medicine, ISSN: 10501738

Nicholas F. Paoni; David G Lowe

October 29, 2001

Comparison between light induced and chemically induced oxidation of rhVEGF

Pharmaceutical Research, ISSN: 07248741

Duenas; Rodney Keck; Abraham M. Devos; Andrew J.S. Jones; Cleland

October 26, 2001

Modification of epidermal growth factor-like repeats with O-fucose: Molecular cloning and expression of a novel GDP-fucose protein O-fucosyltransferase

Journal of Biological Chemistry, ISSN: 00219258

Yang Wang; Li Shao; Shaolin Shi; Reed J. Harris; Spellman; Pamela Stanley; Robert S. Haltiwanger

October 23, 2001

Overexpression of the HER-2/neu oncogene in pancreatic adenocarcinoma

American Journal of Clinical Oncology: Cancer Clinical Trials, ISSN: 02773732

Howard Safran; Margaret Steinhoff; Shamlal Mangray; Ritesh Rathore; Thomas Charles King; Li Chai; Katya Berzein; Todd Moore; David Iannitti; Philip Reiss; Terese Pasquariello; Paul Akerman; Daniel Quirk; Robert Mass; Lisa Goldstein; Umadevi Tantravahi

October 22, 2001

Purification of brain peroxisomes and localization of 3-hydroxy-3-methylglutaryl coenzyme A reductase

European Journal of Biochemistry, ISSN: 00142956

Werner J. Kovacs; Phyllis L. Faust; Gilbert-Andre Keller; Skaidrite Krisans

October 20, 2001

Characterization of filter extractables by proton NMR spectroscopy: Studies on intact filters with process buffers

PDA Journal of Pharmaceutical Science and Technology, ISSN: 10797440

Kao; Bender; Hagewiesche; Wong; Huang; Vanderlaan

October 20, 2001

Metabolic oscillations in an E. Coli fermentation

Biotechnology and Bioengineering, ISSN: 00063592

Dana C. Andersen; James R. Swartz; Thomas Ryll; Lin; Snedecor

October 19, 2001

Identification of a Novel Rab11/25 Binding Domain Present in Eferin and Rip Proteins

Journal of Biological Chemistry, ISSN: 00219258

Rytis Prekeris; Jason M. Davies; Richard H. Scheller

October 19, 2001

Axin-dependent Phosphorylation of the Adenomatous Polyposis Coli Protein Mediated by Casein Kinase 1ε

Journal of Biological Chemistry, ISSN: 00219258

Bonnee Rubinfeld; David A. Tice; Paul G. Polakis

October 15, 2001

Identifiability of cure models

Statistics and Probability Letters, ISSN: 01677152

Chin-Shang Li; Jeremy M.G. Taylor; Sy

October 12, 2001

The 1.85 Å resolution crystal structures of tissue factor in complex with humanized FaB D3h44 and of free humanized FaB D3h44: Revisiting the solvation of antigen combining sites

Journal of Molecular Biology, ISSN: 00222836

Katja Faelber; Daniel Kirchhofer; Presta; Robert F. Kelley; Yves A. Muller

October 10, 2001

Dobutamine stress cine-MRI of cardiac function in the hearts of adult cardiomyocyte-specific VEGF knockout mice

Journal of Magnetic Resonance Imaging, ISSN: 10531807

Simon P. Williams; Hans-Peter Gerber; Frank J. Giordano; Franklin V. Peale Jr.; Lisa J. Bernstein; Bunting; Kenneth R. Chien; Napoleone Ferrara; Nicholas Van Bruggen

October 9, 2001

Remote intermolecular "heavy-atom effect": Spin-orbit coupling across the wall of a hemicarcerand

Journal of the American Chemical Society, ISSN: 00027863

Romanova; Deshayes; Piotrowiak

October 9, 2001

Preclinical studies to predict the disposition of Apo2L/tumor necrosis factor-related apoptosis-inducing ligand in humans: Characterization of in vivo efficacy, pharmacokinetics, and safety

Journal of Pharmacology and Experimental Therapeutics, ISSN: 00223565

Kelley; Louise A. Harris; David Xie; Laura DeForge; Klara Totpal; Bussiere; Judy Fox

October 8, 2001

DNA methylation in genomic imprinting, development, and disease

Journal of Pathology, ISSN: 00223417

Gretchen D. Frantz; Thinh Q. Pham; Franklin V. Peale Jr.; Kenneth J. Hillan

October 8, 2001

The Cancer Genome Anatomy Project: New resources for reading the molecular signatures of cancer

Journal of Pathology, ISSN: 00223417

Maughan; Lewis; Victoria Smith

October 8, 2001

Analysing gene expression data from DNA microarrays to identify candidate genes

Journal of Pathology, ISSN: 00223417

Thomas D Wu

October 8, 2001

Synthesis of tetrasubstituted thiophenes on solid-support using the Gewald reaction

Tetrahedron Letters, ISSN: 00404039

Georgette M. Castanedo; Daniel P. Sutherlin

October 8, 2001

An introduction to arrays

Journal of Pathology, ISSN: 00223417

Kenneth J. Hillan; Philip Quirke

October 8, 2001

Unlocking the archive - Gene expression in paraffin-embedded tissue

Journal of Pathology, ISSN: 00223417

Lewis; Maughan; Victoria Smith; Kenneth J. Hillan; Quirke E

October 2, 2001

Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency

Current Biology, ISSN: 09609822

Minhong Yan; John B.B. Ridgway; Betty Chan; Wyne P. Lee; Benjamin Hsu; Susan Harless; Michael Cancro; Iqbal S. Grewal; Vishva M. Dixit

October 1, 2001

ALCAM (CD166): Its role in hematopoietic and endothelial development

Blood, ISSN: 00064971

Osamu Ohneda; Kinuko Ohneda; Fumio Arai; James Lee; Takeshi Miyamoto; Yoshimi Fukushima; Dowbenko; Lasky; Toshio Suda

October 1, 2001

A new nomenclature for IL-1-family genes

Trends in Immunology, ISSN: 14714906

John E Sims; Yang Pan; Dirk Smith; Martin J.H Nicklin; Jenny L Barton; J.Fernando Bazan; Robert A. Kastelein; Samantha J Busfield; John E Ford; Haishan Lin; Julio J Mulero; Sanjay Kumar; James Pan; Peter R Young

October 1, 2001

Dynamics of Notch expression during murine prostate development and tumorigenesis

Cancer Research, ISSN: 00085472

Shou; Ross; Koeppen; Frederic J. De Sauvage; Gao

October 1, 2001

IL-17s adopt a cystine knot fold: Structure and activity of a novel cytokine, IL-17F, and implications for receptor binding

EMBO Journal, ISSN: 02614189

Sarah G. Hymowitz; Ellen H. Filvaroff; Jianping Yin; James Lee; Liping Cai; Risser; Maruoka; Mao; Foster; Robert F. Kelley; Pan; Austin L. Gurney; De Vos; Melissa A. Starovasnik

September 26, 2001

The PYRIN domain: A member of the death domain-fold superfamily

Protein Science, ISSN: 09618368

Wayne J. Fairbrother; Nathaniel C. Gordon; Eric W. Humke; Karen M. O'Rourke; Melissa A. Starovasnik; Jianping Yin; Vishva M. Dixit

September 26, 2001

Progress in the use of biological assays during the development of biotechnology products

Pharmaceutical Research, ISSN: 07248741

Mire-Sluis

September 19, 2001

Application of the TIMI risk score for ST-elevation MI in the National Registry of Myocardial Infarction 3

JAMA - Journal of the American Medical Association, ISSN: 00987484

David A. Morrow; Elliott M. Antman; Lori Parsons; James A. De Lemos; Christopher P. Cannon; Robert P. Giugliano; Carolyn H. McCabe; Hal V. Barron; Eugene Braunwald

September 18, 2001

Crystal structure of human insulin-like growth factor-1: Detergent binding inhibits binding protein interactions

Biochemistry, ISSN: 00062960

Vajdos; Ultsch; Schaffer; Deshayes; Jinfeng Liu; Nicholas J. Skelton; De Vos

September 15, 2001

Phage display: Increasing the rewards from genomic information

Drug Discovery Today, ISSN: 13596446

Sachdev S. Sidhu

September 12, 2001

Manipulation of ligand binding affinity by exploitation of conformational coupling

Nature Structural Biology, ISSN: 10728368

Jonathan S. Marvin; Homme W. Hellinga

September 12, 2001

Mutant β-spectrin 4 causes auditory and motor neuropathies in quivering mice

Nature Genetics, ISSN: 10614036

Nicholas J. Parkinson; Christine Olsson; Janice L. Hallows; Jennifer Mckee-Johnson; Bart P. Keogh; Konrad Noben-Trauth; Sharon G. Kujawa; Bruce L Tempel

September 7, 2001

Characterization and humanization of a monoclonal antibody that neutralizes human leukocyte interferon: A candidate therapeutic for IDDM and SLE

Cytokine, ISSN: 10434666

Anan Chuntharapai; Lai; Huang; Gibbs; K.Jin Kim; Presta; Stewart

September 1, 2001

Capillary Electrophoresis as a routine analytical tool in pharmaceutical analysis

LCGC North America, ISSN: 15275949

Kevin D. Altria; Chen; Lilian Clohs

September 1, 2001

Similarity of the Escherichia coli proteome upon completion of different biopharmaceutical fermentation processes.

Proteomics, ISSN: 16159853

Kathleen M. Champion; Julie C. Nishihara; John C. Joly; David Arnott

September 1, 2001

Training future chemical biologists

Chemical Innovation, ISSN: 15274799

Gregory A. Weiss

August 31, 2001

Dissociation of Heparan Sulfate and Receptor Binding Domains of Hepatocyte Growth Factor Reveals that Heparan Sulfate-c-Met Interaction Facilitates Signaling

Journal of Biological Chemistry, ISSN: 00219258

Jeffrey S. Rubin; Regina M. Day; Diane Breckenridge; Nese Atabey; William G. Taylor; Stephen J. Stahl; Paul T. Wingfield; Joshua D. Kaufman; Ralph H. Schwall; Donald P. Bottaro

August 30, 2001

Identification of an angiogenic mitogen selective for endocrine gland endothelium

Nature, ISSN: 00280836

Jennifer Lecouter; Joe Kowalski; Foster; Hass; Zemin Zhang; Lisa Dillard-Telm; Gretchen D. Frantz; Linda Rangell; Leo Deguzman; Gilbert-Andre Keller; Franklin V. Peale Jr.; Austin L. Gurney; Kenneth J. Hillan; Napoleone Ferrara

August 24, 2001

Affinity-reversed-phase liquid chromatography assay to quantitate recombinant antibodies and antibody fragments in fermentation broth

Journal of Chromatography A, ISSN: 00219673

John E. Battersby; Snedecor; Christina Y. Chen; Kathleen M. Champion; Riddle; Vanderlaan

August 21, 2001

Use of pilot plant facilities to aid validation programs

PDA Journal of Pharmaceutical Science and Technology, ISSN: 10797440

O'Leary; Etcheverry; Bezy; Vincent R. Anicetti; Burton

August 21, 2001

A novel family of hairpin peptides that inhibit IgE activity by binding to the high-affinity IgE receptor

Biochemistry, ISSN: 00062960

Nakamura; Melissa A. Starovasnik; Mark E. Reynolds; Henry B. Lowman

August 16, 2001

Sorbitol dehydrogenase inhibitors (SDIs): A new potent, enantiomeric SDI, 4-[2-1R-hydroxy-ethyl)-pyrimidin-4-yl]-piperazine-1-sulfonic acid dimethylamide

Journal of Medicinal Chemistry, ISSN: 00222623

Mylari; Oates; Beebe; Brackett; Coutcher; Dina; Zembrowski

August 14, 2001

Selection and characterization of a new class of peptide exosite inhibitors of coagulation factor VIIa

Biochemistry, ISSN: 00062960

Dennis; Roberge; Quan; Lazarus

August 14, 2001

The Sec6/8 complex in mammalian cells: Characterization of mammalian Sec3, subunit interactions, and expression of subunits in polarized cells

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Hugo T. Matern; Charles Yeaman; W. James Nelson; Richard H. Scheller

August 11, 2001

Cardiotrophin-1 can protect cardiac myocytes from injury when added both prior to simulated ischaemia and at reoxygenation

Cardiovascular Research, ISSN: 00086363

Bhawanjit K. Brar; Anastatis Stephanou; Zhihong Liao; O'Leary; Diane Pennica; Derek M Yellon; David S. Latchman

August 11, 2001

The factor VII zymogen structure reveals reregistration of β strands during activation

Structure, ISSN: 09692126

Eigenbrot; Daniel Kirchhofer; Dennis; Santell; Lazarus; Jennifer Stamos; Ultsch

August 6, 2001

αvβ3 antagonists based on a central thiophene scaffold

Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X

Peyman; Karl-Heinz Scheunemann; Will; Knolle; Volkmar Wehner; Breipohl; Stilz; Denis Carniato; Ruxer; Gourvest; Auberval; Doucet; Roland Baron; Gaillard; Thomas Gadek; Bodary

August 6, 2001

Activation and accumulation of B cells in TACI-deficient mice

Nature Immunology, ISSN: 15292908

Minhong Yan; Hua Wang; Betty Chan; Merone Roose-Girma; Sharon Erickson; Thad Baker; Daniel B. Tumas; Iqbal S. Grewal; Vishva M. Dixit

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