Genentech: Publications

January 1, 1999

Deficient T cell fate specification in mice with an induced inactivation of Notch1

Immunity, ISSN: 10747613

Freddy Radtke; Anne Wilson; Gerlinde Stark; Michele Bauer; Joost Van Meerwijk; H. Robson MacDonald; Michel Aguet

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January 1, 1999

Effect of local anti-VEGF antibody treatment on tumor microvessel permeability

Microvascular Research, ISSN: 00262862

Hera C. Lichtenbeld; Napoleone Ferrara; Rakesh K. Jain; Lance L. Munn

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January 1, 1999

IgE inhibition as a therapy for allergic disease

International Archives of Allergy and Immunology, ISSN: 10182438

Paula Jardieu; Robert B. Fick Jr.

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January 1, 1999

Safety assessment of single-bolus administration of TNK tissue- plasminogen activator in acute myocardial infarction: The ASSENT-1 trial

American Heart Journal, ISSN: 00028703

Frans Van De Werf; Christopher P. Cannon; Anne Luyten; Katrijn Houbracken; Carolyn H. McCabe; Berioli; Bluhmki; Hans Sarelin; Wang-Clow; Fox; Eugene Braunwald

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January 1, 1999

A comparison of the national registry of myocardial infarction 2 with the cooperative cardiovascular project

Journal of the American College of Cardiology, ISSN: 07351097

Nathan R. Every; Paul D. Frederick; Michael Robinson; Jonathan Sugarman; Laura J. Bowlby; Hal V. Barron

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January 1, 1999

Hepatocyte growth factor inhibits amiloride-sensitive Na+ channel function in cystic fibrosis airway epithelium in vitro

Pulmonary Pharmacology and Therapeutics, ISSN: 10945539

Shen; Widdicombe; Mrsny

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January 1, 1999

Transformation by v-Src: Ras-MAPK and PI3K-mTOR mediate parallel pathways

Molecular Biology of the Cell, ISSN: 10591524

Elicia M. Penuel; G. Steven Martin

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January 1, 1999

The effect of growth hormone treatment on stature in Aarskog syndrome

Journal of Pediatric Endocrinology and Metabolism, ISSN: 0334018X

Anna Petryk; Samuel Richten; Judy P. Sy; Sandra L. Blethen

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January 1, 1999

Depletion of eosinophils in mice through the use of antibodies specific for C-C chemokine receptor 3 (CCR3)

Journal of Leukocyte Biology, ISSN: 07415400

Grimaldi; Nai-Xuan Yu; Gabrielle Grunig; Brian W. P. Seymour; Françoise Cottrez; Douglas S. Robinson; Nancy Hosken; Walter G. Ferlin; Xiaoyan Wu; Hortensia Soto; Anne O'Garra; Maureen C. Howard; Coffman

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January 1, 1999

Pharmacokinetics and pharmacodynamics of sibrafiban, an orally administered IIb/IIIa antagonist, in patients with acute coronary syndrome.

Journal of Clinical Pharmacology, ISSN: 00912700

Modi; Novotny; Reimann; Christopher P. Cannon; Braunwauld

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January 1, 1999

Probing intermolecular backbone H-bonding in serine proteinase-protein inhibitor complexes

Chemistry and Biology, ISSN: 10745521

Wuyuan Lu; Michael Randal; Anthony A. Kossiakoff; Stephen B. H. Kent

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January 1, 1999

Triggering cell death: The crystal structure of Apo2L/TRAIL in a complex with death receptor 5

Molecular Cell, ISSN: 10972765

Sarah G. Hymowitz; Hans W. Christinger; Fuh; Ultsch; Mark P. O'Connell; Robert F. Kelley; Avi Ashkenazi; De Vos

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January 1, 1999

Safety and antitumor activity of recombinant soluble Apo2 ligand

Journal of Clinical Investigation, ISSN: 00219738

Avi Ashkenazi; Roger Pai; Fong; Susan Leung; David Lawrence; Scot A. Marsters; Christine Blackie; Ling Chang; Amy E. McMurtrey; Andrea Hebert; Laura DeForge; Iphigenia Koumenis; Lewis; Louise A. Harris; Bussiere; Koeppen; Shahrokh; Ralph H. Schwall

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January 1, 1999

Correlation of CT findings with clinical evaluations in 261 patients with symptomatic bronchiectasis

American Journal of Roentgenology, ISSN: 0361803X

David A. Lynch; John Newell; Valerie Hale; Debra Dyer; Kevin Corkery; Fox; Patricia Gerend; Robert B. Fick Jr.

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January 1, 1999

Lyophilization of protein formulations in vials: Investigation of the relationship between resistance to vapor flow during primary drying and small-scale product collapse

Journal of Pharmaceutical Sciences, ISSN: 00223549

David E. Overcashier; Thomas W. Patapoff; Chung C. Hsu

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January 1, 1999

Anatomic localization of 24- and 96-h particle retention in canine airways

Journal of Applied Physiology, ISSN: 87507587

Kreyling; Blanchard; Godleski; Haeussermann; Heyder; Hutzler; Schulz; Sweeney; Takenaka; Ziesenis

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January 1, 1999

Commentary: Role of the pathologist in the identification and characterization of therapeutic molecules

Toxicologic Pathology, ISSN: 01926233

Anne Ryan

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January 1, 1999

Inhibitory mechanism of the CXCR4 antagonist T22 against human immunodeficiency virus type 1 infection

Journal of Virology, ISSN: 0022538X

Tsutomu Murakami; Tian-Yuan Zhang; Yoshio Koyanagi; Yuetsu Tanaka; Jin Kim; Yoichi Suzuki; Shigeru Minoguchi; Hirokazu Tamamura; Michinori Waki; Akiyoshi Matsumoto; Nobutaka Fujii; Hisatoshi Shida; James A. Hoxie; Stephen C. Peiper; Naoki Yamamoto

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January 1, 1999

Development and testing of a thermoluminescence dosemeter for mixed neutron-photon-beta radiation fields

Radiation Protection Dosimetry, ISSN: 01448420

Zummo; Liu

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January 1, 1999

The biology of human epidermal growth factor receptor 2.

Current Oncology Reports, ISSN: 15233790

Sundaresan; Elicia M. Penuel; Mark X. Sliwkowski

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January 1, 1999

Functional roles for PECAM-1 (CD31) and VE-cadherin (CD144) in tube assembly and lumen formation in three-dimensional collagen gels

American Journal of Pathology, ISSN: 00029440

Suya Yang; Jennifer Graham; Jeanne Kahn; Eric A. Schwartz; Mary E. Gerritsen

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January 1, 1999

Real time quantitative PCR as a method to evaluate simian virus 40 removal during pharmaceutical protein purification

Biologicals, ISSN: 10451056

Shi; Lenore A Norling; Allen S.L. Lau; Sherrie Krejci; Alison J. Laney; Yuan Xu

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January 1, 1999

A real time quantitative PCR-based method for the detection and quantification of simian virus 40

Biologicals, ISSN: 10451056

Shi; Jeniffer Ho; Lenore A Norling; Margaret Roy; Yuan Xu

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January 1, 1999

Role of vascular endothelial growth factor in the regulation of angiogenesis

Kidney International, ISSN: 00852538

Napoleone Ferrara

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January 1, 1999

A human antibody that binds to the γ-carboxyglutamic acid domain of factor IX is a potent antithrombotic in vivo

Thrombosis and Haemostasis, ISSN: 03406245

Refino; Jacques Himber; Louis Burcklen; Paul Moran; Peek; Shelley Suggett; Devaux; Daniel Kirchhofer

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January 1, 1999

Allergic bronchopulmonary aspergillosis in cystic fibrosis: Reported prevalence, regional distribution, and patient characteristics

Chest, ISSN: 00123692

David E. Geller; Kaplowitz; Michael Light; Andrew A. Colin

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January 1, 1999

FGF-19, a novel fibroblast growth factor with unique specificity for FGFR4

Cytokine, ISSN: 10434666

Xie; Ilona N. Holcomb; Bethanne Deuel; Patrick Dowd; Arthur Huang; Alicia Vagts; Foster; Jie Liang; Brush; Qimin Gu; Kenneth J. Hillan; Goddard; Austin L. Gurney

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January 1, 1999

Role of baseline parameters in determining indirect pharmacodynamic responses

Journal of Pharmaceutical Sciences, ISSN: 00223549

Sun; William J. Jusko

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January 1, 1999

Pharmacokinetics of insulin-like growth factor I in hypopituitarism: Correlation with binding proteins

American Journal of Physiology - Endocrinology and Metabolism, ISSN: 01931849

Nelly Mauras; Quarmby; Duane C. Bloedow

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January 1, 1999

How much insulin-like growth factor-I (IGF-I) circulates?: impact of standardization on IGF-I assay accuracy.

Developments in biological standardization, ISSN: 03015149

Quarmby; Quan

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January 1, 1999

Kinase Receptor Activation (KIRA): a rapid and accurate alternative to endpoint bioassays.

Developments in biological standardization, ISSN: 03015149

Michael D Sadick

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January 1, 1999

Chromatography of recombinant proteins.

Developments in biological standardization, ISSN: 03015149

O'Connor

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January 1, 1999

Conformational changes in the activation loop of the insulin receptor's kinase domain

Protein Science, ISSN: 09618368

Mark Frankel; Steven M. Bishop; Ararat J. Ablooglu; Yuan-Ping Han; Ronald A. Kohanski

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January 1, 1999

Development of noradrenergic neurons in the zebrafish hindbrain requires BMP, FGF8, and the homeodomain protein soulless/Phox2a

Neuron, ISSN: 08966273

Guo; Brush; Hiroki Teraoka; Goddard; Stephen W. Wilson; Mary C. Mullins; Rosenthal

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January 1, 1999

Creatine: a review of efficacy and safety.

Journal of the American Pharmaceutical Association (Washington,D.C. : 1996), ISSN: 10865802

Graham; Hatton

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January 1, 1999

Airway epithelial CFTR mRNA expression in cystic fibrosis patients after repetitive administration of a recombinant adenovirus

Journal of Clinical Investigation, ISSN: 00219738

Ben-Gary Harvey; Philip L. Leopold; Neil R. Hackett; Tina M. Grasso; P. Mickey Williams; Ayly Ling Tucker; Robert J. Kaner; Barbara Ferris; Gonda; Sweeney; Ramachandran Ramalingam; Kovesdi; Steven Shak; Crystal

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January 1, 1999

A common mechanism for recombinant human NGF, BDNF, NT-3, and murine NGF slow unfolding

Protein Science, ISSN: 09618368

Linda R. De Young; Charles H. Schmelzer; Louis E. Burton

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January 1, 1999

Hypertension and endothelial dysfunction in apolipoprotein E knockout mice

Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN: 10795642

Renhui Yang; Powell-Braxton; Annie Ko Ogaoawara; Noel Dybdal; Bunting; Osamu Ohneda; Hongkui Jin

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January 1, 1999

Comparisons of the Intraocular Tissue Distribution, Pharmacokinetics, and Safety of 125I-Labeled Full-Length and Fab Antibodies in Rhesus Monkeys Following Intravitreal Administration

Toxicologic Pathology, ISSN: 01926233

Joyce Mordenti; R. Andrew Cuthbertson; Napoleone Ferrara; Karen Thomsen; Lea Berleau; Vojtech Licko; Philip C. Allen; Celia R. Valverde; Meng; David T.W. Fei; Kathleen M. Fourre; Anne Ryan

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January 1, 1999

Intraocular pharmacokinetics and safety of a humanized monoclonal antibody in rabbits after intravitreal administration of a solution or a PLGA microsphere formulation

Toxicological Sciences, ISSN: 10966080

Joyce Mordenti; Karen Thomsen; Vojtech Licko; Lea Berleau; Jeanne Kahn; R. Andrew Cuthbertson; Duenas; Anne Ryan; Cheryl A. Schofield; Terrence W. Berger; Meng; Cleland

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January 1, 1999

Expression of the mucosal vascular addressin, MAdCAM-1, in inflammatory liver disease

Liver, ISSN: 01069543

Kenneth J. Hillan; Kelly E. Hagler; Roderick N. M. MacSween; Anne Ryan; Renz; Chiu; Rod K. Ferrier; George L. Bird; Amar P. Dhillon; Linda D. Ferrell; Sherman Fong

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January 1, 1999

Neuregulin receptor-mediated gene transfer by human epidermal growth factor receptor 2-targeted antibodies and neuregulin-1

Cancer Gene Therapy, ISSN: 09291903

Jeffrey Kern; Robert Wakita; Mark X. Sliwkowski

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January 1, 1999

Characterization of a candidate Borrella burgdorferi β3-chain integrin ligand identified using a phage display library

Molecular Microbiology, ISSN: 0950382X

Jenifer Coburn; Wambui Chege; Loranne Magoun; Bodary; John M. Leong

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January 1, 1999

RIPs: An emerging family of kinases involved in pro-inflammatory and apoptotic signaling

Cold Spring Harbor Symposia on Quantitative Biology, ISSN: 00917451

Vishva M. Dixit

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January 1, 1999

Anti-IgE as novel therapy for the treatment of asthma

Current Opinion in Pulmonary Medicine, ISSN: 10705287

Robert B. Fick Jr.

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January 1, 1999

Secondary reduction in the apparent diffusion coefficient of water, increase in cerebral blood volume, and delayed neuronal death after middle cerebral artery occlusion and early reperfusion in the rat

Journal of Cerebral Blood Flow and Metabolism, ISSN: 0271678X

Menno Van Lookeren Campagne; Roger Thomas; Harold Thibodeaux; James T. Palmer; Simon P. Williams; David G Lowe; Nicholas Van Bruggen

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January 1, 1999

VEGF antagonism reduces edema formation and tissue damage after ischemia/reperfusion injury in the mouse brain

Journal of Clinical Investigation, ISSN: 00219738

Nicholas Van Bruggen; Harold Thibodeaux; James T. Palmer; Wyne P. Lee; Ling Fu; Cairns; Daniel B. Tumas; Gerlai; Simon P. Williams; Menno Van Lookeren Campagne; Napoleone Ferrara

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January 1, 1999

Heregulin enhances regenerative proliferation in postnatal rat utricular sensory epithelium after ototoxic damage

Journal of Neurocytology, ISSN: 03004864

Zheng; Gretchen D. Frantz; Lewis; Mark X. Sliwkowski; Gao

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January 1, 1999

Capillary electrophoresis sodium dodecyl sulfate nongel sieving analysis of a therapeutic recombinant monoclonal antibody: A biotechnology perspective

Analytical Chemistry, ISSN: 00032700

Glenn Hunt; Wassim Nashabeh

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January 1, 1999