Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 12301 - 12350 OF 15612 RESULTS

Evidence that insulin-like growth factor I and growth hormone are required for prostate gland development
Endocrinology, ISSN: 00137227
Weifeng Ruan; Powell-Braxton; John J. Kopchick; David Kleinberg
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Effects of Igf1 gene deletion on postnatal growth patterns
Endocrinology, ISSN: 00137227
Jie Wang; Jian Zhou; Powell-Braxton; Carolyn Bondy
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Selective cloning of cell surface proteins involved in organ development: Epithelial glycoprotein is involved in normal epithelial differentiation
Endocrinology, ISSN: 00137227
Jean-Philippe Stephan; Penelope E. Roberts; Bald; James Lee; Qimin Gu; Devaux; Mather
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Analytical ultracentrifugation in the pharmaceutical industry
Journal of Pharmaceutical Sciences, ISSN: 00223549
Jun Liu; Steven J. Shire
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Somatotroph and lactotroph changes in the adenohypophyses of mice with disrupted insulin-like growth factor I gene
Endocrinology, ISSN: 00137227
Lucia Stefaneanu; Powell-Braxton; Wesley B. Won; Varadaraj Chandrashekar; Andrzej Bartke
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Elastase substrate specificity tailored through substrate-assisted catalysis and phage display
Protein Engineering, ISSN: 02692139
William Dall'Acqua; Cornelia Halin; Maria L. Rodrigues; Paul J. Carter
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Induction of apoptosis in cancer cells by tumor necrosis factor and butyrolactone, an inhibitor of cyclin-dependent kinases
Brazilian Journal of Medical and Biological Research, ISSN: 1414431X 0100879X
Belizário; Steve Sherwood; Beçak
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Expression of the mucosal vascular addressin, MAdCAM-1, in inflammatory liver disease
Liver, ISSN: 01069543
Kenneth J. Hillan; Kelly E. Hagler; Roderick N. M. MacSween; Anne Ryan; Renz; Chiu; Rod K. Ferrier; George L. Bird; Amar P. Dhillon; Linda D. Ferrell; Fong
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Role of baseline parameters in determining indirect pharmacodynamic responses
Journal of Pharmaceutical Sciences, ISSN: 00223549
Yu-Nien Sun; William J. Jusko
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Crystal structure of the complex between VEGF and a receptor-blocking peptide
Biochemistry, ISSN: 00062960
Wiesmann; Hans W. Christinger; Andrea G Cochran; Cunningham; Wayne J. Fairbrother; Christopher J. Keenan; Meng; De Vos
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Novel peptides selected to bind vascular endothelial growth factor target the receptor-binding site
Biochemistry, ISSN: 00062960
Wayne J. Fairbrother; Hans W. Christinger; Andrea G Cochran; Fuh; Christopher J. Keenan; Quan; Stephanie K. Shriver; Jeffrey Tom; James A. Wells; Cunningham
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Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer
Nature, ISSN: 00280836
Pitti; Scot A. Marsters; David Lawrence; Margaret Roy; Frank C. Kischkel; Patrick Dowd; Arthur Huang; Christopher J. Donahue; Steve Sherwood; Daryl T. Baldwin; Godowski; William I. Wood; Austin L. Gurney; Kenneth J. Hillan; Robert L. Cohen; Goddard; David Botstein; Avi Ashkenazi
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Host defense molecule polymorphisms influence the risk for immune- mediated complications in chronic granulomatous disease
Journal of Clinical Investigation, ISSN: 00219738
Charles B. Foster; Thomas Lehrnbecher; Femke Mol; Seth M. Steinberg; David J. Venzon; Thomas J. Walsh; Noack; Julie Rae; Jerry A. Winkelstein; John T. Curnutte; Stephen J. Chanock
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Crystal structure of the MATa1/MATα2 homeodomain heterodimer in complex with DNA containing an A-tract
Nucleic Acids Research, ISSN: 03051048
Thomas Li; Yisheng Jin; Andrew K. Vershon; Cynthia Wolberger
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Safety and immunogenicity of HIV recombinant envelope vaccines in HIV- infected infants and children
Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, ISSN: 10779450
John S. Lambert; James McNamara; Samuel L. Katz; Terry Fenton; Minhee Kang; Thomas C. VanCott; Robert Livingston; Elizabeth Hawkins; Jack Moye Jr.; William Borkowsky; Daniel Johnson; Ram Yogev; A-M. Duliege; Francis; Anne Gershon; Diane W. Wara; Natasha L. Martin; Myron Levin; George McSherry; Gale Smith
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Compendium of excipients for parenteral formulations
PDA Journal of Pharmaceutical Science and Technology, ISSN: 10797440
Powell; Tue H. Nguyen; Baloian
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Probing the importance of second sphere residues in an esterolytic antibody by phage display
Journal of Molecular Biology, ISSN: 00222836
Michelle R. Arkin; James A. Wells
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Triplet energy transfer through the walls of hemicarcerands: Temperature dependence and the role of internal reorganization energy
Journal of the American Chemical Society, ISSN: 00027863
Ileana Place; Angeles Farran; Deshayes; Piotrowiak
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WISP genes are members of the connective tissue growth factor family that are up-regulated in Wnt-1-transformed cells and aberrantly expressed in human colon tumors
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Diane Pennica; Todd A. Swanson; James W. Welsh; Margaret Roy; David Lawrence; James Lee; Brush; Lisa A. Taneyhill; Bethanne Deuel; Michael Lew; Colin K. Watanabe; Robert L. Cohen; Mona F. Melhem; Gene G. Finley; Philip Quirke; Goddard; Kenneth J. Hillan; Austin L. Gurney; David Botstein; Arnold J. Levine
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Chinese hamster ovary cells with constitutively expressed sialidase antisense RNA produce recombinant DNase in batch culture with increased sialic acid
Biotechnology and Bioengineering, ISSN: 00063592
Ferrari; Jane Gunson; James A. Lofgren; Lynne Krummen; Warner
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Real-time control of purified product collection during chromatography of recombinant human insulin-like growth factor-I using an on-line assay
Journal of Chromatography A, ISSN: 00219673
Fahrner; Philip M. Lester; Gregory S. Blank; David H. Reifsnyder
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Conformations of thioamide-containing dipeptides: A computational study
Journal of the American Chemical Society, ISSN: 00027863
Dean R. Artis; Mark A. Lipton
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7 Ty Mutagenesis
Methods in Microbiology, ISSN: 05809517
David J. Garfinkel; M. Joan Curcio; Victoria Smith
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A carboxypeptidase inhibitor markedly improves the potency of tPA in-vivo
Fibrinolysis and Proteolysis, ISSN: 13690191
Refino; Schmitt; Cheryl Pater; Bunting
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Dose-dependence and repeated-dose studies for receptor/gene-mediated pharmacodynamics of methylprednisolone on glucocorticoid receptor down- regulation and tyrosine aminotransferase induction in rat liver
Journal of Pharmacokinetics and Biopharmaceutics, ISSN: 0090466X
Sun; Debra C. DuBois; Richard R. Almon; Nancy A. Pyszczynski; William J. Jusko
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Fast Edman cycles with accelerated PTH analysis
Protein Journal, ISSN: 15723887 15734943
William J. Henzel; Jake Tropea; Kishiyama; Wendy Shillinglaw; David Dupont; Steve O'Neil
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Mucosal administration of a non-toxic pseudomonas exotoxin-gpllo V3 loop chimera elevates gpllO specific IgG and IgA in the serum and saliva of balb/c mice
FASEB Journal, ISSN: 08926638
Daugherty; Suva; Charlotte M. Fryling; David FitzGerald; Mrsny
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Acetogenesis does not replace ketogenesis in fasting piglets infused with hexanoate
American Journal of Physiology, ISSN: 00029513
Adams; Jack Odle
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Development of V3-loop pseudomonas exotoxin chimeras: Candidate vaccines for human immunodeficiency virus-1
FASEB Journal, ISSN: 08926638
David FitzGerald; Charlotte M. Fryling; Marian McKee; Ann L. Danghcrty; Randall J. Mj-sny
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The specification of sympathetic neurotransmitter phenotype depends on gp130 cytokine receptor signaling
Development (Cambridge), ISSN: 09501991
Markus Geissen; Stefan Heller; Diane Pennica; Uwe Ernsberger; Hermann Rohrer
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Treatment of indolent lymphoma with fludarabine/mitoxantrone combination: A phase II trial
Hematological Oncology, ISSN: 02780232
Christos Emmanouilides; Peter Rosen; Sara Rasti; Mary Territo; Lori Kunkel
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Transfer of a protein binding epitope to a minimal designed peptide
Biopolymers - Peptide Science Section, ISSN: 00063525
Quan; Nicholas J. Skelton; Clark; Jackson; Renz; Chiu; Keating; Beresini; Sherman Fong; Dean R. Artis
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Transfer of a protein binding epitope to a minimal designed peptide
Biopolymers - Peptide Science Section, ISSN: 00063525
Quan; Nicholas J. Skelton; Clark; Jackson; Renz; Chiu; Keating; Beresini; Fong; Dean R. Artis
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Dose-dependence and repeated-dose studies for receptor/gene-mediated pharmacodynamics of methylprednisolone on glucocorticoid receptor down- regulation and tyrosine aminotransferase induction in rat liver
Journal of Pharmacokinetics and Biopharmaceutics, ISSN: 0090466X
Yu-Nien Sun; Debra C. DuBois; Richard R. Almon; Nancy A. Pyszczynski; William J. Jusko
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Analysis of repeated markers used to predict progression of cancer
Statistics in Medicine, ISSN: 02776715
Birol Emir; Sam Wieand; John Q. Su; Steve Cha
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The Drosophila inhibitor of apoptosis D-IAP1 suppresses cell death induced by the caspase drICE
FEBS Letters, ISSN: 00145793
William J. Kaiser; Domagoj Vucic; Lois K. Miller
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Translocation of human calcitonin in respiratory nasal epithelium is associated with self-assembly in lipid membrane
Biochemistry, ISSN: 00062960
M. Christiane Schmidt; Barbara Rothen-Rutishauser; Beate Rist; Annette Beck-Sickinger; Heidi Wunderli-Allenspach; Rubas; Wolfgang Sadée; Hans P. Merkle
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A transient expansion of the native state precedes aggregation of recombinant human interferon-γ
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Brent Kendrick; John F. Carpenter; Cleland; Theodore W. Randolph
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Crystal structure of the NK1 fragment of human hepatocyte growth factor at 2.0 Å resolution
Structure, ISSN: 09692126
Ultsch; Lokker; Godowski; De Vos
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Changes in thyroid hormone levels during growth hormone therapy in initially euthyroid patients: Lack of need for thyroxine supplementation
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
David T. Wyatt; Gesundheit; Barry M. Sherman
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Metabolic consequences of 5-year growth hormone (GH) therapy in children treated with GH for idiopathic short stature
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
Saenger; Kenneth M. Attie; Dimartino-Nardi; Hintz; Frahm; James W. Frane; Ann J. Johanson; Joyce Baptista; Joyce Kuntze; Robert M. Blizzard; Cara; Chernausek; Geffner; Gertner; Hopwood; Kaplan; Barbara M. Lippe; Plotnick; Alan D. Rogol
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PSTPIP 2, a second tyrosine phosphorylated, cytoskeletal-associated protein that binds a PEST-type protein-tyrosine phosphatase
Journal of Biological Chemistry, ISSN: 00219258
Yan Wu; Dowbenko; Lasky
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Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway: Requirement for Flk-1/KDR activation
Journal of Biological Chemistry, ISSN: 00219258
Hans-Peter Gerber; Amy E. McMurtrey; Joe Kowalski; Minhong Yan; Keyt; Vishva M. Dixit; Napoleone Ferrara
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Corticotropin regulates vascular endothelial growth factor expression in human fetal adrenal cortical cells
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
Jan L. Shifren; Sam Mesiano; Robert N. Taylor; Napoleone Ferrara; Robert B. Jaffe
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Protein targeting in the analysis of learning and memory: A potential alternative to gene targeting
Experimental Brain Research, ISSN: 00144819
Gerlai; Simon P. Williams; Cairns; Nicholas Van Bruggen; Paul Moran; Shih; Caras; Hans Sauer; Phillips; Winslow
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Characterization of two patched receptors for the vertebrate hedgehog protein family
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
David Carpenter; Donna Stone; Brush; Anne Ryan; Armanini; Gretchen D. Frantz; Rosenthal; Frederic J. De Sauvage
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Blunted thrombopoietin response to interferon alfa-induced thrombocytopenia during treatment for hepatitis C
Hepatology, ISSN: 02709139
Markus Peck-Radosavljevic; Martina Wichlas; Johann Pidlich; Paul Sims; Meng; Johannes Zacherl; Shaily Garg; Christian Datz; Alfred Gangl; Peter Ferenci
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Caspase-14 is a novel developmentally regulated protease
Journal of Biological Chemistry, ISSN: 00219258
Shimin Hu; Scott J. Snipas; Claudius Vincenz; Guy S. Salvesen; Vishva M. Dixit
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Homologous up-regulation of KDR/Flk-1 receptor expression by vascular endothelial growth factor in vitro
Journal of Biological Chemistry, ISSN: 00219258
Shen; David Y. Lee; Hans-Peter Gerber; Keyt; Napoleone Ferrara; Zioncheck
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Nuclear integration of glucocorticoid receptor and nuclear factor-κB signaling by CREB-binding protein and steroid receptor coactivator-1
Journal of Biological Chemistry, ISSN: 00219258
Kelly-Ann Sheppard; Kathleen M. Phelps; Amy J. Williams; Dimitris Thanos; Christopher K. Glass; Michael G. Rosenfeld; Mary E. Gerritsen; Tucker Collins
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