Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 12951 - 13000 OF 15612 RESULTS

January 1, 1997

The Pharmaceutical Development of Insulin: Historical Perspectives and Future Directions

ACS Symposium Series, ISSN: 00976156

Henry R. Costantino; Stanley Liauw; Samir Mitragotri; Langer; Klibanov; Victoria Sluzky

January 1, 1997

P-115. Recombinant human (rh) GHBP: Effects on GH action in the rat

Endocrinology and Metabolism, Supplement, ISSN: 1074939X

Deborah L. Mortensen; Carlsson; Winkler; Ross Clark

January 1, 1997

Hematologically important mutations: X-linked chronic granulomatous disease - An update

Blood Cells, Molecules, and Diseases, ISSN: 10799796

Heyworth; John T. Curnutte; Julie Rae; Noack; Andrew R. Cross

January 1, 1997

NGF binding to p75 enhances the sensitivity of sensory and sympathetic neurons to NGF at different stages of development

Molecular and Cellular Neuroscience, ISSN: 10447431

Antony Horton; Laramee; Sean Wyatt; Shih; Winslow; Alun M. Davies

January 1, 1997

Specification and Survival of Dopaminergic Neurons in the Mammalian Midbrain

Advances in Pharmacology, ISSN: 10543589

Rosenthal

January 1, 1997

Targeting technologies - The expanding patent literature

Journal of Drug Targeting, ISSN: 1061186X

Mrsny

January 1, 1997

Developing Pharmaceutical Protein Formulations: Assumptions and Analytical Tools

ACS Symposium Series, ISSN: 00976156

Shahrokh

January 1, 1997

Determining the water sorption monolayer of lyophilized pharmaceutical proteins

Journal of Pharmaceutical Sciences, ISSN: 00223549

Henry R. Costantino; Curley; Chung C. Hsu

January 1, 1997

Peripheral vascular stenosis in apolipoprotein e-deficient mice: Potential roles of lipid deposition, medial atrophy, and adventitial inflammation

Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN: 10795642

Hong Seog Seo; Donna M. Lombardi; Patti Polinsky; Powell-Braxton; Bunting; Schwartz; Michael E. Rosenfeld

January 1, 1997

A risk-benefit assessment of growth hormone use in children

Drug Safety, ISSN: 01145916

Sandra L. Blethen; Margaret H. Macgillivray

January 1, 1997

National Cooperative Growth Study substudy VI: The clinical utility of growth-hormone-binding protein, insulin-like growth factor I, and insulin- like growth factor-binding protein 3 measurements

Journal of Pediatrics, ISSN: 00223476

Kenneth M. Attie; Joanne R. Julius; Catherine Stoppani; Amy Chen Rundle

January 1, 1997

Pioneering recombinant growth hormone manufacturing: Pounds produced per mile of height

Journal of Pediatrics, ISSN: 00223476

Cronin

January 1, 1997

Partial growth-hormone insensitivity: The role of growth-hormone receptor mutations in idiopathic stature

Journal of Pediatrics, ISSN: 00223476

Goddard; Patrick Dowd; Chernausek; Geffner; Gertner; Hintz; Hopwood; Selna L. Kaplan; Plotnick; Alan D. Rogol; Rosenfield; Saenger; Nelly Mauras; Hershkopf; Angulo; Kenneth M. Attie

January 1, 1997

Consequences of growth hormone deficiency on cardiac structure, function, and β-adrenergic pathway: Studies in mutant dwarf rats

Endocrinology, ISSN: 00137227

Antonio Cittadini; Hinrik Strömer; Dorothy E. Vatner; Jessica D. Grossman; Sarah E. Katz; Ross Clark; James P. Morgan; Pamela Douglas

January 1, 1997

Vascular endothelial growth factor expression is higher in differentiated thyroid cancer than in normal or benign thyroid

Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X

Euy Y. Soh; Quan-Yang Duh; Saif A. Sobhi; Dave M. Young; Howard D. Epstein; Mariwil G. Wong; Y. Kit Garcia; Young D. Min; Richard F. Grossman; Allan E. Siperstein; Orlo H. Clark

January 1, 1997

Factors influencing the time to thrombolysis in acute myocardial infarction

Archives of Internal Medicine, ISSN: 00039926

Costas Lambrew; Laura J. Bowlby; William J. Rogers; Nisha C. Chandra; Douglas Weaver

December 21, 1996

Glycopinion: Biological significance and methods for the analysis of complex carbohydrates of recombinant glycoproteins

Biotechnology and Applied Biochemistry, ISSN: 08854513

T. Shantha Raju; Laura Lerner; O'Connor

December 21, 1996

Cardiotrophin-1 inhibits tumor necrosis factor production in the heart and serum of lipopolysaccharide-treated mice and in vitro in mouse blood cells

American Journal of Pathology, ISSN: 00029440

Fabio Benigni; Silvano Sacco; Diane Pennica; Pietro Ghezzi

December 17, 1996

The far upstream element-binding proteins comprise an ancient family of single-strand DNA-binding transactivators

Journal of Biological Chemistry, ISSN: 00219258

Terri Davis-Smyth; Robert C. Duncan; Tian Zheng; Gregory Michelotti; David Levens

December 17, 1996

Solution structure of the E-domain of Staphylococcal protein A

Biochemistry, ISSN: 00062960

Melissa A. Starovasnik; Nicholas J. Skelton; Mark P. O'Connell; Robert F. Kelley; Dorothea Reilly; Wayne J. Fairbrother

December 15, 1996

Neural cell type-specific expression of QKI proteins is altered in quakingviable mutant mice

Journal of Neuroscience, ISSN: 02706474

Rebecca J. Hardy; Carrie L. Loushin; Victor L. Friedrich Jr.; Qi Chen; Tom A. Ebersole; Robert A. Lazzarini; Karen Artzt

December 14, 1996

Crystallization of the receptor binding domain of vascular endothelial growth factor

Proteins: Structure, Function and Bioinformatics, ISSN: 08873585

Hans W. Christinger; Yves A. Muller; Lea Berleau; Keyt; Cunningham; Napoleone Ferrara; De Vos

December 13, 1996

Variable structures of Fis-DNA complexes determined by flanking DNA-protein contacts

Journal of Molecular Biology, ISSN: 00222836

Clark Q. Pan; Steven E. Finkel; Sarah E. Cramton; Jin-An Feng; David S. Sigman; Reid C. Johnson

December 10, 1996

Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Fan Yuan; Yi Chen; Marc Dellian; Nina Safabakhsh; Napoleone Ferrara; Rakesh K. Jain

December 1, 1996

Modulation of LFA-1 by an anti-cdlla antibody which distributes to lfa-1-expresslng cells in blood, spleen, liver, bone marrow, and kidney

FASEB Journal, ISSN: 08926638

Barbara Reitz; Washington; Hotaling; Wolfgang-feimball; Anne Ryan; Ramon Widmer; Betty Chan; Gilbert-Andre Keller; Kenneth D. Bauer; Paula Jardieu; Judy Fox

December 1, 1996

Structure-function studies of human interferon-a receptor II using mabs

FASEB Journal, ISSN: 08926638

Anan Chumharapai; Lu; Jin

December 1, 1996

Molecular recognition in protein complexes

FASEB Journal, ISSN: 08926638

James A. Wells; Brian C. Cunnmgham; Betty Li; Melissa A. Starovasnik; Wayne J. Fairbrother; Andrew Braisted

December 1, 1996

Basement membrane and repair of injury to peripheral nerve: Defining a potential role for macrophages, matrix metalloproteinases, and tissue inhibitor of metalloproteinases-1

Journal of Experimental Medicine, ISSN: 00221007

Monique La Fleur; Johnnie L. Underwood; Daniel A. Rappolee; Zena Werb

December 1, 1996

Induction of apoptosis by APO-2 ligand, a new member of the TNF cytokine family

FASEB Journal, ISSN: 08926638

Avi Ashkenazi; Pitti; Scot A. Marsters; Siegfried Ruppert; Christopher J. Donahue; Alison Moore

December 1, 1996

Induction of autoimmune t cells and costimulatory ligands b7 and icam-1 by interferon-alpha

FASEB Journal, ISSN: 08926638

Debasis Chakrabarti; Hultgren; Timothy

December 1, 1996

Are there more members of the CNTF-GPA family?

Perspectives on Developmental Neurobiology, ISSN: 10640517

David L. Shelton

December 1, 1996

Identification of a GDP-L-fucose:polypeptide fucosyltransferase and enzymatic addition of O-linked fucose to EGF domains

Glycobiology, ISSN: 09596658

Yang Wang; Geoffrey F. Lee; Robert F. Kelley; Spellman

December 1, 1996

Elevated blood pressure and enhanced myocardial contractility in mice with severe IGF-1 deficiency

Journal of Clinical Investigation, ISSN: 00219738

Giuseppe Lembo; Howard A. Rockman; John J. Hunter; Hope Steinmetz; Walter J. Koch; Lan Ma; Morton P. Prinz; John Ross Jr.; Kenneth R. Chien; Powell-Braxton

December 1, 1996

Predominate neuronal localization of a soluble sialidase in Chinese hamster brain

FASEB Journal, ISSN: 08926638

Dybdal; Oline; Li; Li; Warner

December 1, 1996

Development of neurotrophic factor therapy for Alzheimer's disease

CIBA Foundation Symposia, ISSN: 03005208

Franz Hefti; Armanini; Klaus D. Beck; Caras; Grace Chan; Godowski; Goodman; R. Glenn Hammonds; Melanie R Mark; Paul Moran; Merry Nishimura; Phillips; Shih; Janet Valverde; Winslow

December 1, 1996

Factors affecting neuronal birth and death in the mammalian olfactory epithelium

CIBA Foundation Symposia, ISSN: 03005208

Anne L. Calof; J. David Holcomb; Jeffrey S. Mumm; Nobuko Hagiwara; Phu Tran; Kirk M. Smith; David L. Shelton

December 1, 1996

Cross-desensitisation of neutrophil IL-8 receptors involves differential receptor subtype regulation

Thorax, ISSN: 00406376

Ian Sabroe; Hébert; Timothy J. Williams; Paul D. Collins

December 1, 1996

Humanization of an Anti-Lymphocyte Function-Associated Antigen (LFA)-1 Monoclonal Antibody and Reengineering of the Humanized Antibody for Binding to Rhesus LFA-1

Journal of Immunology, ISSN: 00221767

Winifred Werther; Gonzalez; Shane J. O'Connor; McCabe; Betty Chan; Hotaling; Mark Champe; Judy Fox; Paula Jardieu; Berman; Presta

December 1, 1996

Modulation of LFA-1 by an anti-cdlla antibody which distributes to lfa-1-expresslng cells in blood, spleen, liver, bone marrow, and kidney

FASEB Journal, ISSN: 08926638

Barbara Reitz; Washington; Hotaling; Wolfgang-feimball; Ryan; Ramon Widmer; Betty Chan; Gilbert-Andre Keller; Kenneth D. Bauer; Paula Jardieu; Judy Fox

December 1, 1996

Functional effects of lymphotoxin on crushed peripheral nerve

Microsurgery, ISSN: 07381085

Javier Algora; Long-En Chen; Anthony V. Seaber; Grace H.W. Wong; James R. Urbaniak

December 1, 1996

Analysis of mixture sequences derived from edman degradation data

Techniques in Protein Chemistry, ISSN: 10808914

William J. Henzel; Stults; Susan C. Wong; Angela K. Namenuk; James Yashio; Colin K. Watanabe

December 1, 1996

Human hepatocyte growth factor in alcoholic liver disease: A comparison with change in α-fetoprotein

Alcoholism: Clinical and Experimental Research, ISSN: 01456008

Charles L. Mendenhall; Roos; Thomas E. Moritz; Gary A. Roselle; Antonio Chedid; Charles J. Grossman; Susan D. Rouster; Bennett; John R. Lake

December 1, 1996

Fourier-transform infrared spectroscopy demonstrates that lyophilization alters the secondary structure of recombinant human growth hormone

Pharmaceutical Sciences, ISSN: 13566881

Henry R. Costantino; Tue H. Nguyen; Chung C. Hsu

December 1, 1996

Multiple roles ofthrombopoietin (TPO) revealed by gene targeting

Experimental Hematology, ISSN: 0301472X

Frederic J. De Sauvage

December 1, 1996

Prostaglandin F2α induces cardiac myocyte hypertrophy in vitro and cardiac growth in vivo

American Journal of Physiology - Heart and Circulatory Physiology, ISSN: 00029513

Lai; Hongkui Jin; Renhui Yang; Jane Winer; Wei; Randy Yen; King; Francis C. Zeigler; Ko Annie; Cheng; Bunting; Nicholas F. Paoni

December 1, 1996

The application of tert-butylhydroperoxide oxidation to study sites of potential methionine oxidation in a recombinant antibody

Techniques in Protein Chemistry, ISSN: 10808914

Felicity J. Shen; Kwong; Rodney Keck; Reed J. Harris

December 1, 1996

The regulation of angiogenesis by vascular endothelial growth factor

FORUM - Trends in Experimental and Clinical Medicine, ISSN: 11218142

Napoleone Ferrara

December 1, 1996

Drug delivery issues in vaccine development

Pharmaceutical Research, ISSN: 07248741

Powell

December 1, 1996

Controlled release technologies: Current status and future prospects

Pharmaceutical Research, ISSN: 07248741

Richard Guy; Powell; Joseph Fix; Kinam Park

December 1, 1996

Fast capillary electrophoresis-laser induced fluorescence analysis of ligase chain reaction products: Human mitochondrial DNA point mutations causing Leber's hereditary optic neuropathy

Electrophoresis, ISSN: 01730835

Jochen Muth; Mickey Williams; Stephen J. Williams; Michael D. Brown; Douglas C. Wallace; Karger

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