Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 13151 - 13200 OF 15613 RESULTS

March 1, 1996

Critical amino acids in the lymphocyte function-associated antigen-1 I domain mediate intercellular adhesion molecule 3 binding and immune function

Journal of Experimental Medicine, ISSN: 00221007

Yvette Van Kooyk; Minke E. Binnerts; Caroline P. Edwards; Mark Champe; Berman; Carl G. Figdor; Bodary

March 1, 1996

Expression and regulation of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in distinct avian motoneuron subsets

Journal of Neurobiology, ISSN: 00223034

Nitza Kahane; David L. Shelton; Chaya Kalcheim

February 28, 1996

Systematic improvement of a chemically-defined protein-free medium for hybridoma growth and monoclonal antibody production

Journal of Biotechnology, ISSN: 01681656

Stoll; Mühlethaler; Von Stockar; Ian W. Marison

February 23, 1996

IRAK: A kinase associated with the interleukin-1 receptor

Science, ISSN: 00368075

Zhaodan Cao; William J. Henzel; Xiong Gao

February 20, 1996

Biological and immunological characterization of inhibin forms in human plasma

Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X

Robertson; Burger; Sullivan; Cahir; Nigel P. Groome; Poncelet; Franchimont; Woodruff; Mather

February 20, 1996

Decreased food intake does not completely account for adiposity reduction after ob protein infusion

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Nancy Levin; Nelson; Austin L. Gurney; Richard Vandleni; Frederic J. De Sauvage

February 16, 1996

Strategies for manipulating apoptosis for cancer therapy with tumor necrosis factor and lymphotoxin

Journal of Cellular Biochemistry, ISSN: 07302312

Grace H.W. Wong; Roger L. Kaspar; Gary Zweiger; Carlson; Fong; Niloofar Ehsani; Gordon A. Vehar

February 16, 1996

The Crystal Structure of the Extracellular Domain of Human Tissue Factor Refined to 1.7 Å Resolution

Journal of Molecular Biology, ISSN: 00222836

Yves A. Muller; Ultsch; De Vos

February 15, 1996

HGF and HGF receptor expresion in the lacrimal gland

Investigative Ophthalmology and Visual Science, ISSN: 01460404

Mohan; Li; Weng; Bennett; Ralph H. Schwall; Wang; Tabor; Kim; Hargrave; Cuevas; Wilson

February 15, 1996

Differential cardiac effects of growth hormone and insulin-like growth factor-1 in the rat: A combined in vivo and in vitro evaluation

Circulation, ISSN: 00097322

Antonio Cittadini; Hinrik Strömer; Sarah E. Katz; Ross Clark; Alan C. Moses; James P. Morgan; Pamela Douglas

February 15, 1996

Tear Hepatocyte Growth Factor (HGF) production increases markedly after excimer laser photorefractive keratoplasty (PRK)

Investigative Ophthalmology and Visual Science, ISSN: 01460404

Qianwa Liang; Tervo; Vesaluoma; Bennett; Ralph H. Schwall; Marco Helena; Wilson

February 15, 1996

Vascular endothelial growth factor promotes tumor dissemination by a mechanism distinct from its effect on primary tumor growth

Cancer Research, ISSN: 00085472

Ostap Melnyk; Shuman; K.Jin Kim

February 15, 1996

Macrophage-mediated apoptosis in the developing mouse eye

Investigative Ophthalmology and Visual Science, ISSN: 01460404

Graciana Diez-Roux; Mark Labow; Horst Bluthman; Mark Moore; Richard Lang

February 13, 1996

Isomerization of an aspartic acid residue in the complementarity-determining regions of a recombinant antibody to human IgE: Identification and effect on binding affinity

Biochemistry, ISSN: 00062960

Cacia; Rodney Keck; Presta; John Frenz

February 10, 1996

A model for metal affinity protein precipitation

Journal of Colloid and Interface Science, ISSN: 00219797

Harish V. Iyer; Todd M. Przybycien

February 9, 1996

Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

Cell, ISSN: 00928674

Marco A. Meraz; J. Michael White; Kathleen C. Sheehan; Bach; Scott J. Rodig; Anand S. Dighe; Daniel H. Kaplan; Riley; Andrew C. Greenlund; Dayle Campbell; Karen Carver-Moore; Raymond N. DuBois; Ross Clark; Michel Aguet; Schreiber

February 8, 1996

High level secretion of a humanized bispecific diabody from Escherichia coli

Bio/Technology, ISSN: 0733222X

Zhu; Gerardo Zapata; Shalaby; Snedecor; Man Chert; Paul J. Carter

February 1, 1996

Physiological regulation of early and late stages of megakaryocytopoiesis by thrombopoietin

Journal of Experimental Medicine, ISSN: 00221007

Frederic J. De Sauvage; Karen Carver-Moore; Shiuh-Ming Luoh; Anne Ryan; Mary Dowd; Dan L. Eaton; Mark Moore

February 1, 1996

The in vivo bioactivity of vascular endothelial growth factor/vascular permeability factor is independent of N-linked glycosylation

Laboratory Investigation, ISSN: 00236837

Dirk H. Walter; Uli Hink; Takayuki Asahara; Eric Van Belle; Jeffrey Horowitz; Yukio Tsurumi; Richard L. Vandlen; Heinsohn; Keyt; Napoleone Ferrara; James F. Symes; Jeffrey M. Isner

February 1, 1996

Electrophoretic separation of recombinant tissue-type plasminogen activator glycoforms: Validation issues for capillary isoelectric focusing methods

Electrophoresis, ISSN: 01730835

Kathy Moorhouse; Carina A. Rickel; Chen

February 1, 1996

Cardiotrophin-1 displays early expression in the murine heart tube and promotes cardiac myocyte survival

Development (Cambridge), ISSN: 09501991

Zelin Sheng; Diane Pennica; William I. Wood; Kenneth R. Chien

February 1, 1996

Identification of a hepatocyte growth factor autocrine loop in a murine mammary carcinoma

Cell Growth and Differentiation, ISSN: 10449523

Nader Rahimi; Eric Tremblay; Laura McAdam; Marg Park; Ralph H. Schwall; Bruce Elliott

January 31, 1996

Multiple immune abnormalities in tumor necrosis factor and lymphotoxin-α double-deficient mice

International Immunology, ISSN: 09538178

Hans-Pietro Eugster; Matthias Müller; Urs Karrer; Bruce D. Car; Bruno Schnyder; Vicki M. Eng; Gaetane Woerly; Michel Le Hir; Franco Di Padova; Michel Aguet; Rolf M. Zinkernagel; Horst Bluethmann; Bernhard Ryffel

January 15, 1996

Hypoxia-induced paracrine regulation of vascular endothelial growth factor receptor expression

Journal of Clinical Investigation, ISSN: 00219738

Edi Brogi; Gina Schatteman; Tiangen Wu; Elizabeth A. Kim; Lyuba Varticovski; Keyt; Jeffrey M. Isner

January 15, 1996

Hematopoietic defects in mice lacking the sialomucin CD34

Blood, ISSN: 00064971

Jill Cheng; Baumhueter; Cacalano; Karen Carver-Moore; Harold Thibodeaux; Thomas; Hal E. Broxmeyer; Cooper; Hague; Mark Moore; Lasky

January 15, 1996

Hematopoietic defects in mice lacking the sialomucin CD34

Blood, ISSN: 00064971

Jill Cheng; Baumhueter; Cacalano; Karen Carver-Moore; Harold Thibodeaux; Thomas; Hal E. Broxmeyer; Scott Cooper; Hague; Mark Moore; Lasky

January 11, 1996

Vascular endothelial growth factor augments muscle blood flow and function in a rabbit model of chronic hindlimb ischemia

Journal of Cardiovascular Pharmacology, ISSN: 01602446

Walder; Carol J. Errett; Bunting; Peter Lindquist; John R. Ogez; Heinsohn; Napoleone Ferrara; G. Roger Thomas

January 11, 1996

Pharmacokinetics and pharmacodynamics of TP-9201, a gpIIbIIIa antagonist, administered in combination with recombinant tissue-type plasminogen activator, heparin, and aspirin in beagles

Journal of Cardiovascular Pharmacology, ISSN: 01602446

Modi; Theresa Reynolds; Sharon A. Baughman; Deborah A. Thomas; Paasch; Susan Yvonne Smith

January 9, 1996

Binding in the growth hormone receptor complex

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

James A. Wells

January 4, 1996

Structure of the saponin adjuvant QS-21 and its base-catalyzed isomerization product by 1 H and natural abundance 13 C NMR spectroscopy

Carbohydrate Research, ISSN: 00086215

Neil E. Jacobsen; Wayne J. Fairbrother; Kensil; Lim; Deborah A. Wheeler; Powell

January 1, 1996

Follistatins and α2-macroglobulin are soluble binding proteins for inhibinand activin

Hormone Research, ISSN: 16632826 16632818

Mather

January 1, 1996

GDNF induces a dystonia-like state in neonatal rats and stimulates dopamine and serotonin synthesis

Neuron, ISSN: 08966273

Klaus D. Beck; Ian Irwin; Janet Valverde; Thomas J. Brennan; J. William Langston; Franz Hefti

January 1, 1996

Regulated release and polarized localization of brain-derived neurotrophic factor in hippocampal neurons

Molecular and Cellular Neuroscience, ISSN: 10447431

Goodman; Janet Valverde; Filip Lim; Michael D. Geschwind; Howard J. Federoff; Alfred I. Geller; Franz Hefti

January 1, 1996

Locating the unpaired cysteine of tissue-type plasminogen activator

Protein Engineering, ISSN: 02692139

Louis C. Sehl; Hung V. Nguyen; Lea Berleau; Patricia Arcila; William F. Bennett; Keyt

January 1, 1996

Human cardiotrophin-1: Protein and gene structure, biological and binding activities, and chromosomal localization

Cytokine, ISSN: 10434666

Diane Pennica; Todd A. Swanson; Kenneth J. Shaw; Wun-Jing Kuang; Christa Gray; Barbara G. Beatty; William I. Wood

January 1, 1996

Liquid-liquid emulsification by rotor/stator homogenization

Journal of Controlled Release, ISSN: 01683659

Maa; Chung C. Hsu

January 1, 1996

Multicopy suppressors of prc mutant Escherichia coli include two HtrA (DegP) protease homologs (HhoAB), DksA, and a truncated rlpA

Journal of Bacteriology, ISSN: 00219193

Bass; Qimin Gu; Anthony Christen

January 1, 1996

Flux measurements across Caco-2 monolayers may predict transport in human large intestinal tissue

Journal of Pharmaceutical Sciences, ISSN: 00223549

Rubas; Cromwell; Shahrokh; Villagran; Nguyen; Wellton; Tue H. Nguyen; Mrsny

January 1, 1996

Penicillamine: An extractable chiral auxiliary providing excellent stereocontrol

Tetrahedron Asymmetry, ISSN: 09574166

Lutz S. Richter; Thomas Gadek

January 1, 1996

Protection of MN-rgp120-immunized chimpanzees from heterologous infection with a primary isolate of human immunodeficiency virus type 1

Journal of Infectious Diseases, ISSN: 00221899

Berman; Murthy; Wrin; Vennari; Kathy Cobb; Eastman; Mark Champe; Nakamura; Donna Davison; Powell; Bussiere; Francis; Matthews; Timothy Gregory; John F. Obijeski

January 1, 1996

Gene targeting in neuroscience: The systemic approach

Trends in Neurosciences, ISSN: 01662236

Gerlai

January 1, 1996

Design and application of a low-temperature Peltier-cooling microscope stage

Journal of Pharmaceutical Sciences, ISSN: 00223549

Chung C. Hsu; Andrew J. Walsh; Hoc M. Nguyen; David E. Overcashier; Hans Koning-Bastiaan; Ralph C. Bailey; Steven L. Nail

January 1, 1996

Vinblastine, a substrate for P-glycoprotein, flux across Caco-2 monolayers and rabbit jejunum

Proceedings of the Controlled Release Society, ISSN: 10220178

Mah; Rubas

January 1, 1996

Baylisascaris procyonis larva migrans in a puppy: A case report and update for the veterinarian

Journal of the American Animal Hospital Association, ISSN: 05872871

Daniel G. Rudmann; Kevin R. Kazacos; Scott T. Storandt; Donna L. Harris; Evan B. Janovitz

January 1, 1996

Development of recombinant human nerve growth factor (rhNGF) as a treatment for peripheral neuropathic disease

NeuroToxicology, ISSN: 0161813X

Rogers

January 1, 1996

Full-length agrin isoform activities and binding site distributions on cultured Xenopus muscle cells

Molecular and Cellular Neuroscience, ISSN: 10447431

David F. Daggett; Donna Stone; H. Benjamin Peng; Nikolics

January 1, 1996

Isomerization and formulation stability of the vaccine adjuvant QS-21

Journal of Pharmaceutical Sciences, ISSN: 00223549

Cleland; Kensil; Lim; Neil E. Jacobsen; Basa; Spellman; Deborah A. Wheeler; Jia-Yan Wu; Powell

January 1, 1996

Evaluation of interleukin-1. Receptor antagonist (IL-1RA) and tumor necrosis factor binding protein (TNF-BP) in a rodent abscess model of host resistance

Immunopharmacology and Immunotoxicology, ISSN: 08923973

Colagiovanni; Shopp

January 1, 1996

Characterization of upper respiratory disease in rats following neonatal inoculation with a rat-adapted influenza virus

Veterinary Pathology, ISSN: 03009858

Dye; Morgan; Neldon; Tepper; Burleson; Costa

January 1, 1996

Caco-2 monolayers as a tool to examine intestinal uptake of particulates

Proceedings of the Controlled Release Society, ISSN: 10220178

Delie; Rubas

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