Genentech: Publications

November 27, 1995

Neurotrophin- 4/5 postpones the death of injured spinal motoneurones in newborn rats

Brain Research, ISSN: 00068993

Schmalbruch; Rosenthal

November 24, 1995

Rapid one-step capillary isoelectric focusing method to monitor charged glycoforms of recombinant human tissue-type plasminogen activator

Journal of Chromatography A, ISSN: 00219673

Kathy Moorhouse; Carina A. Eusebio; Glenn Hunt; Chen

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November 21, 1995

Growth hormone secretagogues: Characterization, efficacy, and minimal bioactive conformation

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Robert S. McDowell; Kathleen A. Elias; Mark S. Stanley; Burdick; Burnier; Kathryn S. Chan; Wayne J. Fairbrother; R. Glenn Hammonds; Gladys S. Ingle; Neil E. Jacobsen; Deborah L. Mortensen; Thomas E. Rawson; Wesley B. Won; Ross Clark; Todd C. Somers

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November 15, 1995

Human TAFII250 interacts with RAP74: Implications for RNA polymerase II initiation

Genes and Development, ISSN: 08909369

Siegfried Ruppert; Robert Tjian

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November 15, 1995

New variant of human tissue plasminogen activator (TPA) with enhanced efficacy and lower incidence of bleeding compared with recombinant human TPA

Circulation, ISSN: 00097322

Claude R. Benedict; Refino; Keyt; Rajbabu Pakala; Nicholas F. Paoni; G. Roger Thomas; William F. Bennett

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November 7, 1995

Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Lloyd Paul Aiello; Eric A. Pierce; Eliot D. Foley; Hitoshi Takagi; Helen Chen; Riddle; Napoleone Ferrara; George L. King; Lois E. H. Smith

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November 1, 1995

Synergistic effect of vascular endothelial growth factor and basic fibroblast growth factor on angiogenesis in vivo

Circulation, ISSN: 00097322

Takayuki Asahara; Christophe Bauters; Lu P. Zheng; Satoshi Takeshita; Bunting; Napoleone Ferrara; James F. Symes; Jeffrey M. Isner

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October 26, 1995

Mutations of the growth hormone receptor in children with idiopathic short stature

New England Journal of Medicine, ISSN: 15334406 00284793

Goddard; Covello; Shiuh-Ming Luoh; Clackson; Kenneth M. Attie; Gesundheit; Amy Chen Rundle; James A. Wells; Carlsson

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October 6, 1995

Transgenic knockouts reveal a critical requirement for pancreatic β cell glucokinase in maintaining glucose homeostasis

Cell, ISSN: 00928674

Andrew Grupe; Hultgren; Anne Ryan; Yan Hui Ma; Michele Bauer; Stewart

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October 1, 1995

Cloning of the murine homolog of the leukemia-associated PML gene

Mammalian Genome, ISSN: 09388990 14321777

Goddard; Jean Q. Yuan; Fairbairn; Dexter; Borrow; Kozak; Solomon

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October 1, 1995

Growth responses to patterned GH delivery

Endocrine, ISSN: 0969711X 15590100

Ross Clark; Deborah L. Mortensen; Carlsson; Carmignac; Icaf Robinson

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October 1, 1995

Engineering linear f(ab')2 fragments for efficient production in Escherichia coli and enhanced antiproliferative activity

Protein Engineering, Design and Selection, ISSN: 17410126

Gerardo Zapata; John B.B. Ridgway; Joyce Mordenti; Gary Osaka; Wai Lee T. Wong; Bennett; Paul J. Carter

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September 25, 1995

A new hepatocyte stimulating factor: cardiotrophin-1 (CT-1)

FEBS Letters, ISSN: 00145793

Malte Peters; Elke Roeb; Diane Pennica; Karl-Hermann Meyer zum Büschenfelde; Stefan Rose-John

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September 15, 1995

Factors influencing the time to administration of thrombolytic therapy with recombinant tissue plasminogen activator (data from the national registry of myocardial infarction)

American Journal of Cardiology, ISSN: 00029149

Charles Maynard|; W.Douglas Weaver; Costas Lambrew; Laura J. Bowlby; William J. Rogers; R. Michael Rubison; The Participants in the National Registry of Myocardial Infarction

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September 8, 1995

Inducible gene targeting in mice

Science, ISSN: 00368075

Ralf Kühn; Frieder Schwenk; Michel Aguet; Klaus Rajewsky

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August 22, 1995

Characterisation of the processing by human neutral endopeptidase 24.11 of GLP-1(7-36) amide and comparison of the substrate specificity of the enzyme for other glucagon-like peptides

Regulatory Peptides, ISSN: 01670115

Karin Hupe-Sodmann; Gerard Patrick McGregor; Robert L. Bridenbaugh; Rüdiger Göke; Burkhard Göke; Hubert Thole; Bodo Zimmermann; Karlheinz Voigt

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August 11, 1995

Reevaluation of the roles of protein S and gas6 as ligands for the receptor tyrosine kinase Rse/Tyro 3

Cell, ISSN: 00928674

Godowski; Melanie R Mark; Jian Chen; Michael D Sadick; Helga Raab; R. Glenn Hammonds

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August 10, 1995

Missing link in angiogenesis

Nature, ISSN: 00280836

Napoleone Ferrara

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August 1, 1995

Recombinant human growth hormone in infants and young children with chronic renal insufficiency

Pediatric Nephrology, ISSN: 0931041X 1432198X

Richard N. Fine; Kenneth M. Attie; Joyce Kuntze; Douglas F. Brown; Edward C. Kohaut

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July 21, 1995

Cytochrome b-245 of the neutrophil superoxide-generating system contains two nonidentical hemes: Potentiometric studies of a mutant form of gp91phox

Journal of Biological Chemistry, ISSN: 00219258

Andrew R. Cross; Julie Rae; John T. Curnutte

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July 21, 1995

A Comparison of neutron diffraction and molecular dynamics structures: Hydroxyl group and water molecule orientations in trypsin

Journal of Molecular Biology, ISSN: 00222836

Robert S. McDowell; Anthony A. Kossiakoff

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July 17, 1995

Allergen-induced histamine release in rat mast cells transfected with the α subunits of FcεRI

Journal of Immunological Methods, ISSN: 00221759

John Lowe; Paula Jardieu; Kimmie VanGorp; David T.W. Fei

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July 15, 1995

Growth hormone improves cardiac performance in experimental heart failure

Circulation, ISSN: 00097322

Renhui Yang; Bunting; Nancy Gillett; Ross Clark; Hongkui Jin

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July 14, 1995

Stimulation of myofibrillar protein synthesis in hindlimb suspended rats by resistance exercise and growth hormone

Life Sciences, ISSN: 00243205

Jon K. Linderman; Justen B. Whittall; Kristin L. Gosselink; Tommy J. Wang; Mukku; Frank W. Booth; Richard E. Grindeland

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July 6, 1995

Stereochemistry of the benzodiazepine based Ras farnesyltransferase inhibitors

Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X

Thomas E. Rawson; Todd C. Somers; James C. Marsters Jr.; Dairian T. Wan; Mark E. Reynolds; Burdick

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June 27, 1995

Interferon γ signals via a high-affinity multisubunit receptor complex that contains two types of polypeptide chain

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Scot A. Marsters; Diane Pennica; Bach; Schreiber; Avi Ashkenazi

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June 23, 1995

Processing of C-terminal lysine and arginine residues of proteins isolated from mammalian cell culture

Journal of Chromatography A, ISSN: 00219673

Reed J. Harris

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June 9, 1995

Isolation of cDNA clones encoding the mouse protein V-1

Gene, ISSN: 03781119

Diane Pennica; Kenneth J. Shaw; Shiuh-Ming Luoh; William I. Wood

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June 6, 1995

Cloning and expression of a second photoreceptor-specific membrane retina guanylyl cyclase (RetGC), RetGC-2

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

David G Lowe; Alexander M. Dizhoor; Kathleen Liu; Qimin Gu; Maribeth Spencer; Richard Laura; Lucy Lu; James B. Hurley

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June 6, 1995

Distinct regions of c-Mpl cytoplasmic domain are coupled to the JAK-STAT signal transduction pathway and Shc phosphorylation

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Austin L. Gurney; Suzan C. Wong; William J. Henzel; Frederic J. De Sauvage

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June 6, 1995

Identification of functionally important helical faces in transmembrane segments by scanning mutagenesis

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Geoffrey F. Lee; David P. Dutton; Gerald L. Hazelbauer

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June 6, 1995

Distinct regions of c-Mpl cytoplasmic domain are coupled to the JAK-STAT signal transduction pathway and Shc phosphorylation

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Austin L. Gurney; Susan C. Wong; William J. Henzel; Frederic J. De Sauvage

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June 1, 1995

Theiler’s virus infection of 129Sv mice that lack the interferon α/ß or interferon γ receptors

Journal of Experimental Medicine, ISSN: 15409538 00221007

Laurence Fiette; Christine Aubert; Ulrike Müller; Sui Huang; Michel Aguet; Michel Brahic; Jean-François Bureau

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June 1, 1995

Reduced recruitment of inflammatory cells in a contact hypersensitivity response in P-selectin-deficient mice

Journal of Experimental Medicine, ISSN: 15409538 00221007

Meera Subramaniam; Simin Saffaripour; Susan R. Watson; Tanya N. Mayadas; Richard O. Hynes; Denisa D. Wagner

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June 1, 1995

Local delivery of vascular endothelial growth factor accelerates reendothelialization and attenuates intimai hyperplasia in balloon-injured rat carotid artery

Circulation, ISSN: 00097322

Takayuki Asahara; Christophe Bauters; Christopher Pastore; Marianne Kearney; Susan T. Rossow; Bunting; Napoleone Ferrara; James F. Symes; Jeffrey M. Isner

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June 1, 1995

Recovery of disturbed endothelium-dependent flow in the collateral-perfused rabbit ischemic hindlimb after administration of vascular endothelial growth factor

Circulation, ISSN: 00097322

Christophe Bauters; Takayuki Asahara; Lu P. Zheng; Satoshi Takeshita; Bunting; Napoleone Ferrara; James F. Symes; Jeffrey M. Isner

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May 29, 1995

Ecotin is a potent inhibitor of the contact system proteases factor XIIa and plasma kallikrein

FEBS Letters, ISSN: 00145793

Jana S. Ulmer; Robert N. Lindquist; Dennis; Lazarus

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May 24, 1995

Protective roles of cytokines against radiation: Induction of mitochondrial MnSOD

Biochimica et Biophysica Acta - Molecular Basis of Disease, ISSN: 09254439

Grace H.W. Wong

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May 23, 1995

Regulation of cell signaling by the cytoplasmic domains of the heat-stable enterotoxin receptor: Identification of autoinhibitory and activating motifs

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Xiaowen L. Rudner; Kathryn K. Mandal; Frederic J. De Sauvage; L. Allen Kindman; June S. Almenoff

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May 12, 1995

A mutant of melanoma growth stimulating activity does not activate neutrophils but blocks erythrocyte invasion by malaria

Journal of Biological Chemistry, ISSN: 00219258

Joseph Hesselgesser; Chitnis; Miller; Yansura; Laura C. Simmons; Wayne J. Fairbrother; Claire Kotts; Wirth; Beth Gillece-Castro; Richard Horuk

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May 1, 1995

Activation and Characterization of Procarboxypeptidase B from Human Plasma

Biochemistry, ISSN: 15204995 00062960

Tan; Dan L. Eaton

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May 1, 1995

The stimulatory effects of interleukin (IL)-12 on hematopoiesis are antagonized by IL-12-induced interferon γ in vivo

Journal of Experimental Medicine, ISSN: 15409538 00221007

Vicki M. Eng; Bruce D. Car; Bruno Schnyder; Meike Lorenz; Serena Lugli; Michel Aguet; Timothy D. Anderson; Bernhard Ryffel; Valerie F. J. Quesniaux

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May 1, 1995

Early interleukin 12 production by macrophages in response to mycobacterial infection depends on interferon γ and tumor necrosis factor α

Journal of Experimental Medicine, ISSN: 15409538 00221007

Inge E. A. Flesch; Jürgen H. Hess; Sui Huang; Michel Aguet; Joachim Rothe; Horst Bluethmann; Stefan H. E. Kaufmann

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April 11, 1995

The retinoblastoma-susceptibility gene product binds directly to the human TATA-binding protein-associated factor TAFII250

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Zhaohui Shao; Siegfried Ruppert; Paul D. Robbins

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April 7, 1995

A variant X-linked chronic granulomatous disease patient (X91⁺) with partially functional cytochrome b

Journal of Biological Chemistry, ISSN: 00219258

Andrew R. Cross; Heyworth; Julie Rae; John T. Curnutte

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April 1, 1995

Proton NMR Assignments and Solution Conformation of RANTES, a Chemokine of the C-C Type

Biochemistry, ISSN: 15204995 00062960

Nicholas J. Skelton; Fernando Aspiras; John R. Ogez; J. Schall Thomas

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April 1, 1995

Insulin-like growth factor-1 and growth hormone (GH) have distinct and overlapping anabolic effects in GH-deficient rats

Endocrine, ISSN: 0969711X 15590100

Ross Clark; Deborah L. Mortensen; Carlsson

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April 1, 1995

The duffy antigen/receptor for chemoklnes (DARC) is expressed in endothelial cells of duffy negative individuals who lack the erythrocyte receptor

Journal of Experimental Medicine, ISSN: 15409538 00221007

Stephen C. Peiper; Zi-Xuan Wang; Kuldeep Neote; Alvin W. Martin; Henry J. Showell; Maryrose J. Conklyn; Kevin Ogborne; Hadley; Zhao-Hai Lu; Joseph Hesselgesser; Richard Horuk

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April 1, 1995

Use of multifactorial analysis to develop aqueous two-phase systems for isolation of non-native IGF-I

Bioseparation, ISSN: 0923179X

Hart; John R. Ogez; Stuart E. Builder

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March 24, 1995

The cytosolic activating factors P47phox and p67phox have distinct roles in the regulation of electron flow in NADPH oxidase

Journal of Biological Chemistry, ISSN: 00219258

Andrew R. Cross; John T. Curnutte

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