Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 14551 - 14600 OF 15613 RESULTS

Monovalent phage display: A method for selecting variant proteins from random libraries
Methods, ISSN: 10959130 10462023
Henry B. Lowman; James A. Wells
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Organ specific cytokine therapy: Local activation of mononuclear phagocytes by delivery of an aerosol of recombinant interferon-γ to the human lung
Journal of Clinical Investigation, ISSN: 00219738
Ari Jaffe; Roland Buhl; Andrea Mastrangeli; Kenneth J. Holroyd; Saltini; Dorothy Czerski; Howard S. Jaffe; Susan M. Kramer; Stephen A. Sherwin; Crystal
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The vascular endothelial growth factor family: Identification of a fourth molecular species and characterization of alternative splicing of rna
Molecular Endocrinology, ISSN: 19449917 08888809
Houck; Napoleone Ferrara; Jane Winer; Cachianes; Bing Li; Leung
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Crystal structure of recombinant rabbit interferon-γ at 2.7-Å resolution
Journal of Biological Chemistry, ISSN: 00219258
Cleopas T. Samudzi; Louis E. Burton; Rubin
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Molecular genetics and drug discovery.
Molecular genetic medicine, ISSN: 10572805
Michael C. Venuti
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Ligand-mediated immunofunctional assay for quantitation of growth hormone-binding protein in human blood
Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X
Carlsson; Rowland; Ross Clark; Gesundheit; Wai Lee T. Wong
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Differential binding of transforming growth factor-β1, -β2, and -β3 by fibroblasts and epithelial cells measured by affinity cross-Linking of cell surface receptors
Molecular Endocrinology, ISSN: 19449917 08888809
Lyons; Duncan A. Miller; Graycar; Moses; Rik Derynck
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Mannosamine, a novel inhibitor of glycosyl-phosphatidylinositole incorporation into proteins
EMBO Journal, ISSN: 02614189
Michael P. Lisanti; Mark C. Field; Caras; Anant K. Menon; Rodriguez-Boulan
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Human nerve growth factor prevents degeneration of basal forebrain cholinergic neurons in primates
Annals of Neurology, ISSN: 15318249 03645134
Vassilis E. Koliatsos; Richard E. Clatterbuck; Haring J. W. Nauta; Beat Knüsel; Louis E. Burton; Franz Hefti; William C. Mobley; Donald L. Price
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Ornatins: potent glycoprotein IIb‐IIIa antagonists and platelet aggregation inhibitors from the leech Placobdella ornata
European Journal of Biochemistry, ISSN: 14321033 00142956
Paul Mazur; William J. Henzel; Jana L. Seymour; Lazarus
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Identification and characterization of cellular binding proteins (receptors) for recombinant human bone morphogenetic protein 2B, an initiator of bone differentiation cascade
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Vishwas M. Paralkar; R. Glenn Hammonds; Reddi
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Isolation and characterization of two peptides with prolactin release-inhibiting activity from porcine hypothalami
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Andrew V. Schally; Janos G. Guoth; Tommie W. Redding; Groot; Rodriguez; Szonyi; Stults; Nikolics
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A potent inhibitor of osteoclastic bone resorption within a highly conserved pentapeptide region of parathyroid hormone-related protein; PTHrP[107–111]
Endocrinology, ISSN: 19457170 00137227
Fenton; Kemp; R. Glenn Hammonds; Mitchelhill; Moseley; Martin; Nicholson
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Antibody engineering using very long template-assembled oligonucleotides
Methods, ISSN: 10959130 10462023
Paul J. Carter; Lisa J. Garrard; Henner
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Promotion of central cholinergic and dopaminergic neuron differentiation by brain-derived neurotrophic factor but not neurotrophin 3
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Beat Knüsel; Winslow; Rosenthal; Louis E. Burton; Derice P. Seid; Karoly Nlkolics; Franz Hefti
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Interaction of apolipoprotein(a) with apolipoprotein B-containing lipoproteins
Journal of Biological Chemistry, ISSN: 00219258
Vuong N. Trieu; Zioncheck; Lawn; Walter D. McConathy
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Industrial scale harvest of proteins from mammalian cell culture by tangential flow filtration
Biotechnology and Bioengineering, ISSN: 10970290 00063592
Van Reis; Lee C. Leonard; Chung C. Hsu; Stuart E. Builder
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Effect of heparin on coronary arterial patency after thrombolysis with tissue plasminogen activator in acute myocardial infarction
American Journal of Cardiology, ISSN: 00029149
Stanley D. Bleich; Timothy C. Nichols; Richard Schumacher; David H. Cooke; David A. Tate; Sam L. Teichman
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Recombinant human DNase I reduces the viscosity of cystic fibrosis sputum
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Shak; Capon; Renate Hellmiss; Scot A. Marsters; Baker
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Identification and design of binding determinants in proteins
Biochemical Society Symposium, ISSN: 00678694
James A. Wells; Cunningham
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Male-specific β-cell dysfunction and diabetes resulting from increased expression of a syngeneic MHC class I protein in the pancreata of transgenic mice
New Biologist, ISSN: 10434674
Martin; Gilbert-Andre Keller; Liggitt; Oakley; Sharon Pitts-Meek; Mark Siegel; Timothy G. Terrell; Stewart
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Parathyroid hormone-related protein: Isolation, molecular cloning, and mechanism of action
Recent Progress in Hormone Research, ISSN: 00799963
Martin; Allan; Caple; Care; Danks; Diefenbach-Jagger; Ebeling; Gillespie; Glenn Hammonds Jr.; Heath; Hudson; Kemp; Kubota; Subhash C. Kukreja; Moseley; Ng; Raisz; Rodda; Simmons; Suva; Wettenhall; William I. Wood
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Requirement for sialic acid on the endothelial ligand of a lymphocyte homing receptor
Journal of Cell Biology, ISSN: 00219525
David D. True; Mark S. Singer; Lasky; Steven D. Rosen
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Post-translational modifications of recombinant human tissue factor
Thrombosis Research, ISSN: 00493848
Lisa R. Paborsky; Reed J. Harris
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Release of phenylpropanolamine from dynamically swelling poly(hydroxyethyl methacrylate-co-methacrylic acid) hydrogels
Polymeric Materials Science and Engineering, Proceedings of the ACS Division of Polymeric Materials Science and Engineering, ISSN: 07430515
Kou; Amidon
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Immunoregulatory role of transforming growth factor β (TGF-β) in development of killer cells: Comparison of active and latent TGF-β1
Journal of Experimental Medicine, ISSN: 15409538 00221007
Wallick; Figari; Randall E. Morris; Levinson; Michael A. Palladino
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Conformation of apolipoprotein B-100 in the low density lipoproteins of Tangier disease. Identification of localized conformational response to triglyceride content
Journal of Biological Chemistry, ISSN: 00219258
Kunitake; Stephen G. Young; G. Chi Chen; Clive R. Pullinger; Shan Zhu; Richard J. Pease; Jamie K. Scott; Hass; James Schilling; Kane
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Photolabeling of the α-nueraminidase/β-galactosidase complex from human placenta with a photoreactive neuraminidase inhibitor
Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X
Warner; Louie; Michel Potier
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Quantification of monoclonal antibodies in complex mixtures by Protein G high-performance liquid affinity chromatography
Analytical Biochemistry, ISSN: 10960309 00032697
Gregory S. Blank; David Vetterlein
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Widespread intradermal accumulation of mononuclear leukocytes in lepromatous leprosy patients treated systemically with recombinant interferon γ
Journal of Experimental Medicine, ISSN: 15409538 00221007
Carl Nathan; Kathleen Squires; William Griffo; William Levis; Matthew Varghese; Job; Asma Nusrat; Stephen A. Sherwin; Samuel Rappoport; Elizabeth Sanchez; Rochel A. Burkhardt; Gilla Kaplan
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Recombinant Expression, Biochemical Characterization, and Biological Activities of the Human MGSA/gro Protein
Biochemistry, ISSN: 15204995 00062960
Rik Derynck; Duanzhi Wen; Rainer Brachmann; Wai Lee T. Wong; Jin Hee Han; H. Greg Thomas; Balentien; Richmond; Ajoy K. Samantha; Claus O. Zachariae; Kouji Matsushima; Patrick Griffin; Ann Richmond
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cDNA sequence of the human integrin β5 subunit
Journal of Biological Chemistry, ISSN: 00219258
McLean; Deborah J. Vestal; David A. Cheresh; Bodary
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Interferon-gamma and the sexual dimorphism of autoimmunity
Molecular Biology and Medicine, ISSN: 07351313
Sarvetnick; Howard S. Fox
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Antibody raised against soluble CD4-rgpl20 complex recognizes the cd4 moiety and blocks membrane fusion without inhibiting CD4-gpl20 binding
Journal of Experimental Medicine, ISSN: 15409538 00221007
Franco Celada; Caterina Cambiaggi; Joan Maccari; Samuele Burastero; Timothy Gregory; Patzer; James P. Porter; Charlene McDanal; Matthews
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The OxyR regulon
Antonie van Leeuwenhoek, International Journal of General and Molecular Microbiology, ISSN: 00036072 15729699
Gisela Storz; Louis A. Tartaglia; Bruce N. Ames
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X-ray Crystal Structure of the Protease Inhibitor Domain of Alzheimer's Amyloid β-Protein Precursor
Biochemistry, ISSN: 15204995 00062960
Eigenbrot; Thomas R. Hynes; Michael Randal; Laura A. Kennedy; Charles Eigenbrot; Anthony A. Kossiakoff
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Enzymatic Cleavage of a CD4 Immunoadhesin Generates Crystallizable, Biologically Active Fd-like Fragments
Biochemistry, ISSN: 15204995 00062960
Steven M. Chamow; Peers; Randal A. Byrn; Michael G. Mulkerrin; Reed J. Harris; Wen-Ching Wang; Pamela J. Bjorkman; Capon; Avi Ashkenazi
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Regulation of G(i) and G(o) by mastoparan, related amphiphilic peptides, and hydrophobic amines. Mechanism and structural determinants of activity
Journal of Biological Chemistry, ISSN: 00219258
Tsutomu Higashijima; Burnier; Elliott M. Ross
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Use of high-performance capillary electrophoresis to monitor charge heterogeneity in recombinant-DNA derived proteins
Journal of Chromatography A, ISSN: 00219673
Shiaw-Lin Wu; Glen Teshima; Cacia; William S. Hancock
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Carbohydrate Characterization of Recombinant Glycoproteins of Pharmaceutical Interest
Analytical Chemistry, ISSN: 15206882 00032700
Spellman
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Additivity of Mutational Effects in Proteins
Biochemistry, ISSN: 15204995 00062960
James A. Wells
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ELISA for quantitation of the extracellular domain of p185HER2 in biological fluids
Journal of Immunological Methods, ISSN: 00221759
Patricia E. Sias; Claire Kotts; David Vetterlein; Michael H. Shepard; Wai Lee T. Wong
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Thermal denaturation profiles and gel mobility shift analysis of oligodeoxynucleotide triplexes
Nucleic Acids Research, ISSN: 03051048
Regan G. Shea; Ng; Norbert Bischofberger
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βγ Dimers of G proteins inhibit atrial muscarinic K+ channels
Journal of Biological Chemistry, ISSN: 00219258
Koji Okabe; Yatani; Tony Evans; Yee-Kin Ho; Juan Codina; Lutz Birnbaumer; Arthur M. Brown
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Serpin Inhibitors of Urokinase and Thrombin in Normal Rat Brain and the 9L Brain Tumor: Evidence for Elevated Expression of Protease Nexin I-like Inhibitor and a Novel Sodium Dodecyl Sulfate-activated Tumor Antithrombin
Cancer Research, ISSN: 15387445 00085472
Rao; Festoff; Baker; Morantz; Kimler; Evans
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Overexpression of protein kinase C α-subtype in Swiss/3T3 fibroblasts causes loss of both high and low affinity receptor numbers for epidermal growth factor
Journal of Biological Chemistry, ISSN: 00219258
Hagit Eldar-Finkelman; Yaffa Zisman; Axel Ullrich; Etta Livneh
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Inhibition of development of Na+-dependent hexose transport in renal epithelial LLC-PK1 cells by differentiation-stimulating factor for myeloid leukemic cells/leukemia inhibitory factor
FEBS Letters, ISSN: 00145793
Tomida; Yuri Yamamoto-Yamaguchi; Hozumi; William E. Holmes; David G Lowe; David V. Goeddel
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Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells
Journal of Biological Chemistry, ISSN: 00219258
Leonard; Spellman; Riddle; Reed J. Harris; James N. Thomas; Timothy Gregory
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Relaxin modulates synthesis and secretion of procollagenase and collagen by human dermal fibroblasts
Journal of Biological Chemistry, ISSN: 00219258
Elaine N. Unemori; Edward P. Amento
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High-performance displacement chromatography-mass spectrometry of tryptic peptides of recombinant human growth hormone
Journal of Chromatography A, ISSN: 00219673
John Frenz; James H. Bourell; William S. Hancock
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