Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 14601 - 14650 OF 15613 RESULTS

July 16, 1990

Cyclic AMP response to recombinant human relaxin by cultured human endometrial cells-A specific and high throughput in vitro bioassay

Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X

David T.W. Fei; Mary C. Gross; Julie A. Lofgren; Mora-Worms; Chen

July 16, 1990

Nerve growth factor (NGF), proNGF and NGF receptor-like immunoreactivity in BB rat retina

Brain Research, ISSN: 00068993

Chakrabarti; Sima; James Lee; Philippe Brachet; Eleni Dicou

July 11, 1990

Synthesis, hybridization properties and antiviral activity of lipid-oligodeoxynucleotide conjugates

Nucleic Acids Research, ISSN: 03051048

Regan G. Shea; James C. Marsters Jr.; Norbert Bischofberger

July 9, 1990

Decorsin. A potent glycoprotein IIb-IIIa antagonist and platelet aggregation inhibitor from the leech Macrobdella decora

Journal of Biological Chemistry, ISSN: 00219258

Jana L. Seymour; William J. Henzel; Nevins; Stults; Lazarus

July 4, 1990

Mannose dependent hepatic uptake and catabolism of tissue plasminogen activator

European Journal of Pharmacology, ISSN: 00142999

Billings; Chen; Spellman; Bakhit

July 1, 1990

Apolipoprotein(a) Size Heterogeneity is Related to Variable Number of Repeat Sequences in Its mRNA

Biochemistry, ISSN: 15204995 00062960

Marlys L. Koschinsky; Beisiegel; Henne-Bruns; Dan L. Eaton; Lawn

July 1, 1990

Structural effects induced by removal of a disulfide-bridge: The x-ray structure of the C30A/C51A mutant of basic pancreatic trypsin inhibitor at 1.6 å

Protein Engineering, Design and Selection, ISSN: 17410126

Eigenbrot; Michael Randal; Anthony A. Kossiakoff

July 1, 1990

Lecithin cholesterol acyl transferase deficiency: molecular analysis of a mutated allele

Human Genetics, ISSN: 03406717 14321203

Roberto Taramelli; Marco Pontoglio; Giulia Candiani; Sergio Ottolenghi; Dieplinger; Alberico Catapano; John Albers; Carlo Vergani; McLean

July 1, 1990

Mutational analysis of the c-terminus of human interferon-γ

Protein Engineering, Design and Selection, ISSN: 17410126

Wetzel; Perry; Connie A. Veilleux; Chang

June 26, 1990

A homing receptor-IgG chimera as a probe for adhesive ligands of lymph node high endothelial venules

Journal of Cell Biology, ISSN: 00219525

Susan R. Watson; Yasuyuki Imai; Christopher Fennie; Joyce S. Geoffroy; Steven D. Rosen; Lasky

June 22, 1990

Preparation of biologically active 32P-labeled human relaxin. Displaceable binding to rat uterus, cervix, and brain

Journal of Biological Chemistry, ISSN: 00219258

Phyllis L. Osheroff; Victor Ling; Richard L. Vandlen; Cronin; Julie A. Lofgren

June 19, 1990

Purification and characterization of recombinant human activin B

Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology, ISSN: 01674838

Charles H. Schmelzer; Louis E. Burton; Cathleen M. Tamony; Ralph H. Schwall; Anthony J. Mason; Nanette Liegeois

June 12, 1990

The ANB1 locus of Saccharomyces cerevisiae encodes the protein synthesis initiation factor eIF-4D

Journal of Biological Chemistry, ISSN: 00219258

Kamal D. Mehta; Leung; Lefebvre; Michael Smith

June 12, 1990

Contribution of the C-terminal dipeptide of transforming growth factor-α to its activity: biochemical and pharmacologic profiles

European Journal of Pharmacology: Molecular Pharmacology, ISSN: 09224106

Song-Gui Yang; Winkler; Morley D. Hollenberg

June 11, 1990

Substance P contracts the human iris sphincter: possible modulation by endogenous enkephalinase

Regulatory Peptides, ISSN: 01670115

Janet A. Anderson; Bernard Malfroy; Normand R. Richard; Laurie Kullerstrand; Catherine Lucas; Perry S. Binder

June 11, 1990

cDNA sequence of the human atrial natriuretic peptide clearance receptor

Nucleic Acids Research, ISSN: 03051048

David G Lowe; Camerato; David V. Goeddle

June 1, 1990

Increase in cyclic AMP levels by relaxin in newborn rhesus monkey uterus cell culture

In Vitro Cellular & Developmental Biology, ISSN: 08838364 14752689

Susan M. Kramer; Ursula E.M. Gibson; Brian M. Fendly; Mohler; Drolet; Paul D. Johnston

May 25, 1990

Nucleotide sequence of the bovine bactericidal permeability increasing protein (BPI)

Nucleic Acids Research, ISSN: 03051048

Leong; Camerato

May 25, 1990

Error rates in oligodeoxynucleotides synthesized by the H-phosphonate method

Nucleic Acids Research, ISSN: 03051048

Vasser; Ng; Jhurani; Norbert Bischofberger

May 16, 1990

The identification and characterization of an epidermal growth factor-stimulated phosphorylation of a specific low molecular weight GTP-binding protein in a reconstituted phospholipid vesicle system

Journal of Biological Chemistry, ISSN: 00219258

Matthew J. Hart; Paul G. Polakis; Tony Evans; Richard A. Cerione

May 16, 1990

The integrin β1 subunit associates with the vitronectin receptor α(v) subunit to form a novel vitronectin receptor in a human embryonic kidney cell line

Journal of Biological Chemistry, ISSN: 00219258

Bodary; McLean

May 1, 1990

Denaturant-Dependent Folding of Bovine Pancreatic Trypsin Inhibitor Mutants with Two Intact Disulfide Bonds

Biochemistry, ISSN: 15204995 00062960

Mark R. Hurle; Cara Berman Marks; Kosen; Anderson; Kuntz

May 1, 1990

Overexpression of human low density lipoprotein receptors leads to accelerated catabolism of Lp(a) lipoprotein in transgenic mice

Journal of Clinical Investigation, ISSN: 00219738

Sandra L. Hofmann; Dan L. Eaton; Michael S. Brown; Walter D. McConathy; Joseph L. Goldstein; Robert E. Hammer

May 1, 1990

Preparation and Properties of Recombinant DNA Derived Tobacco Mosaic Virus Coat Protein

Biochemistry, ISSN: 15204995 00062960

Steven J. Shire; McKay; Leung; Cachianes; Eugene Jackson; William I. Wood; Krishnamurthy Raghavendra; Lamia Khairallah; Todd M. Schuster

April 20, 1990

Molecular cloning and expression of a receptor for human tumor necrosis factor

Cell, ISSN: 00928674

Thomas J. Schall; Lewis; Koller; Angela Lee; Glenn C. Rice; Grace H.W. Wong; Tetsuya Gatanaga; Gale A. Granger; Rigdon Lentz; Helga Raab; William J. Kohr; David V. Goeddel

April 16, 1990

The promoter of the glucoamylase-encoding gene of Aspergillus niger functions in Ustilago maydis

Gene, ISSN: 03781119

Timothy L. Smith; Jill Gaskell; Randy M. Berka; Yang; Henner; Cullen

April 2, 1990

Interaction of wild-type and catalytically inactive mutant forms of tissue-type plasminogen activator with human umbilical vein endothelial cell monolayers

Journal of Biological Chemistry, ISSN: 00219258

Vanitha Ramakrishnan; Sinicropi; Randall Dere; Darbonne; Bechtol; Baker

April 1, 1990

Plasminogen Activator Activities of Equimolar Complexes of Streptokinase with Variant Recombinant Plasminogens

Biochemistry, ISSN: 15204995 00062960

Donald J. Davidson; Deborah L. Higgins; Francis J. Castellino

March 23, 1990

The human growth hormone receptor. Secretion from Escherichia coli and disulfide bonding pattern of the extracellular binding domain

Journal of Biological Chemistry, ISSN: 00219258

Fuh; Michael G. Mulkerrin; Bass; Nancy McFarland; Michael Brochier; James H. Bourell; Light; James A. Wells

March 22, 1990

Growth hormone–receptor gene in laron dwarfism

New England Journal of Medicine, ISSN: 15334406 00284793

Bass; James A. Wells; Serge Amselem; Philippe Duquesnoy; Olivier Attree; Giuseppe Novelli; Souad Bousnina; Marie-Catherine Postel-Vinay; Michel Goossens

March 1, 1990

Characterization of Murine Monoclonal Antibodies Reactive to Either the Human Epidermal Growth Factor Receptor or HER2/neu Gene Product

Cancer Research, ISSN: 15387445 00085472

Brian M. Fendly; Marcy Winget; Hudziak; Michael T. Lipari; Napier; Axel Ullrich

March 1, 1990

A General Method for Highly Selective Cross-Linking of Unprotected Polypeptides via pH-Controlled Modification of N-Terminal α-Amino Groups

Bioconjugate Chemistry, ISSN: 15204812 10431802

Wetzel; Roger Halualani; Stults; Quan

February 15, 1990

The effect of the one-chain to two-chain conversion in tissue plasminogen activator: Characterization of mutations at position 275

Thrombosis Research, ISSN: 00493848

Deborah L. Higgins; M.Christine Lamb; Young; Powers; Anderson

February 2, 1990

Application of high-performance hydrophobic-interaction chromatography to the characterization of recombinant DNA-derived human growth hormone

Journal of Chromatography A, ISSN: 00219673

Shiaw-Lin Wu; William S. Hancock; Bohdan Pavlu; Par Gellerfors

February 2, 1990

The Mel 14 antibody binds to the lectin domain of the murine peripheral lymph node homing receptor

Journal of Cell Biology, ISSN: 00219525

Bowen; Christopher Fennie; Lasky

February 1, 1990

Organization of the Human Cholesteryl Ester Transfer Protein Gene

Biochemistry, ISSN: 15204995 00062960

Luis B. Agellon; Elaine M. Quinet; Thomas G. Gillette; Maryanne L. Brown; Alan R. Tall; Drayna

January 23, 1990

Vectorial secretion of extracellular matrix proteins, matrix-degrading proteinases, and tissue inhibitor of metalloproteinases by endothelial cells

Journal of Biological Chemistry, ISSN: 00219258

Elaine N. Unemori; Karyn S. Bouhana; Zena Werb

January 19, 1990

Automated evaluation of tryptic digest from recombinant human growth hormone using ultraviolet spectra and numeric peak information

Journal of Chromatography A, ISSN: 00219673

Hans-Jurgen P. Sievert; Wu Shiaw-Lin; Chloupek; William S. Hancock

January 19, 1990

Analysis of glycoprotein-derived oligosaccharides by high-pH anion-exchange chromatography

Journal of Chromatography A, ISSN: 00219673

Basa; Spellman

January 15, 1990

Differential Regulation of Expression of Three Transforming Growth Factor 0 Species in Human Breast Cancer Cell Lines by Estradiol

Cancer Research, ISSN: 15387445 00085472

Arrick; Murray Korc; Rik Derynck

January 15, 1990

Immunomodulatory and Toxic Effects of Free and Liposome-encapsulated Tumor Necrosis Factor a in Rats1

Cancer Research, ISSN: 15387445 00085472

Robert J. Debs; Henry J. Fuchs; Ramila Philip; Elisa N. Brunette; Nejat Düzgüneş; Judd E. Shellito; Liggitt; John R. Patton

January 1, 1990

Serotonin Receptor “Families” in the Central Nervous System: An Overview

Annals of the New York Academy of Sciences, ISSN: 17496632 00778923

Peroutka; ANNE W. SCHMIDT; Andrew J. Sleight; Harrington

January 1, 1990

A Sensitive Radioimmunoprecipitation Assay for the Detection and Quantitation of Antibodies to the Envelope Glycoprotein gp120 of the Human Immunodeficiency Virus (HIV-1)

AIDS Research and Human Retroviruses, ISSN: 19318405 08892229

Catherine Lucas; Peterson; Bennett; Frie; Berman; Chen

January 1, 1990

Properties of a cleaved two‐chain form of recombinant human growth hormone

International Journal of Peptide and Protein Research, ISSN: 13993011 03678377

Eleanor Canova-Davis; Ida P. Baldonado; Moore; Rudman; William F. Bennett; William S. Hancock

January 1, 1990

Calibration of polyacrylamide gel columns for the separation of oligonucleotides by capillary electrophoresis

Electrophoresis, ISSN: 15222683 01730835

Aran Paulus; Ernst Gassmann; Field

January 1, 1990

Mapping the CD4 binding site for human immunodeficiency virus by alanine-scanning mutagenesis

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Avi Ashkenazi; Presta; Scot A. Marsters; Camerato; Rosenthal; Brian M. Fendly; Capon

January 1, 1990

Widespread expression of BDNF but not NT3 by target areas of basal forebrain cholinergic neurons

Science, ISSN: 00368075

Phillips; Hains; Laramee; Rosenthal; Winslow

January 1, 1990

Localization of inhibin/activin subunit mRANS within the primate ovary

Molecular Endocrinology, ISSN: 19449917 08888809

Ralph H. Schwall; Anthony J. Mason; Josiah N. Wilcox; Steven G. Bassett; Anthony J. Zeleznik

January 1, 1990

Primary sequence of cyclic nucleotide phosphodiesterase isozymes and the design of selective inhibitors

Trends in Pharmacological Sciences, ISSN: 01656147

Joseph A. Beavo; David H. Reifsnyder

January 1, 1990

Serum tumor necrosis factor alpha associated with acute graft-versus-host disease in humans

Transplantation, ISSN: 00411337

Frank W. Symington; Margaret Sullivan Pepe; Chen; Anna Deliganis

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