Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 14751 - 14800 OF 15613 RESULTS

January 1, 1990

Preparation and Characterization of Conjugates of Recombinant CD4 and Deglycosylated Ricin A Chain Using Different Cross-Linkers

Bioconjugate Chemistry, ISSN: 15204812 10431802

Victor Ghetie; Mark A. Till; Maria-Ana Gnette; Thomas Tucker; James P. Porter; Patzer; James A. Richardson; Jonathan W. Uhr; Ellen S. Vitetta

January 1, 1990

Quality control of rDNA-derived human tissue-type plasminogen activator.

Bioprocess technology, ISSN: 08887470

Andrew J.S. Jones; Robert L. Garnick

January 1, 1990

Regional Distribution of α‐[3H]Amino‐3‐Hydroxy‐5‐Methylisoxazole‐4‐Propionic Acid Binding Sites in Rat Brain: Effect of Chemical Modification of SH– Groups in Tissue Sections

Journal of Neurochemistry, ISSN: 14714159 00223042

Michel Baudry; Daniel Monaghan; Carl Cotman; C.Anthony Altar

January 1, 1990

5’ -Phosphorylation of oligonucleotides with phosphorous acid in automated dna synthesis

Nucleosides and Nucleotides, ISSN: 07328311

James C. Marsters Jr.; Ng; Jhurani; Vasser; Norbert Bischofberger

January 1, 1990

Acidic fibroblast growth factor (HBGF‐1) stimulates DNA synthesis in primary rat hepatocyte cultures

Journal of Cellular Physiology, ISSN: 10974652 00219541

Houck; Reza Zarnegar; Stephanie J. Muga; George K. Michalopoulos

January 1, 1990

Folding of eukaryotic proteins produced in Escherichia coli.

Genetic engineering, ISSN: 01963716

Robert F. Kelley; Winkler

January 1, 1990

Serotonin Receptor “Families” in the Central Nervous System: An Overview

Annals of the New York Academy of Sciences, ISSN: 17496632 00778923

Peroutka; ANNE W. SCHMIDT; Andrew J. Sleight; MELISSA A. HARRINGTON

January 1, 1990

Hormone phage: An enrichment method for variant proteins with altered binding properties

Proteins: Structure, Function and Bioinformatics, ISSN: 10970134 08873585

Bass; Ronald Greene; James A. Wells

January 1, 1990

A precise and rapid microtitre plate clot lysis assay: Methodology, kinetic modeling and measurement of catalytic constants for plasminogen activation during fibrinolysis

Thrombosis and Haemostasis, ISSN: 03406245

Andrew J.S. Jones; Meunier

January 1, 1990

Expression of cloned proteins in mammalian cells: regulation of cell-associated parameters.

Bioprocess technology, ISSN: 08887470

Mather; Tsao

January 1, 1990

Chapter 31. The Impact of Biotechnology on Drug Discovery

Annual Reports in Medicinal Chemistry, ISSN: 00657743

Michael C. Venuti

January 1, 1990

Functionally distinct insulin receptors generated by tissue-specific alternative splicing

EMBO Journal, ISSN: 02614189

Luitgard Mosthaf; Grako; Dull; Lisa Coussens; Axel Ullrich; Donald A. McClain

January 1, 1990

Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor α: Relevance to genetic predisposition to systemic lupus erythematosus

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Chaim O. Jacob; Zdenka Fronek; Gail D. Lewis; May Koo; John A. Hansen; Hugh O. McDevitt

January 1, 1990

Hydroxyl hydrogen conformations in trypsin determined by the neutron diffraction solvent difference map method: Relative importance of steric and electrostatic factors in defining hydrogen-bonding geometries

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Anthony A. Kossiakoff; Shpungin; Sintchak

January 1, 1990

Connective tissue metabolism including cytokines

Current Opinion in Rheumatology, ISSN: 10408711

Elaine N. Unemori; Edward P. Amento

January 1, 1990

Downstream processing of proteins from mammalian cells.

Bioprocess technology, ISSN: 08887470

John R. Ogez; Stuart E. Builder

January 1, 1990

Activin stimulates spermatogonial proliferation in germ-sertoli cell cocultures from immature rat testis

Endocrinology, ISSN: 19457170 00137227

Mather; Kenneth M. Attie; Woodruff; Glenn C. Rice; David M. Phillips

January 1, 1990

Role of hemostatic defect during thrombolytic therapy with recombinant tissue-type plasminogen activator

Thrombosis Research, ISSN: 00493848

David Stump

January 1, 1990

Vectorial apical delivery and slow endocytosis of a glycolipid-anchored fusion protein in transfected MDCK cells

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Michael P. Lisanti; Caras; Gilbert; David Hanzel; Rodriguez-Boulan

January 1, 1990

Structural characterization of a recombinant CD4‐IgG hybrid molecule

European Journal of Biochemistry, ISSN: 14321033 00142956

Reed J. Harris; Karen L. Wagner; Spellman

January 1, 1990

Inhibin and activin locally regulate rat ovarian folliculogenesis

Endocrinology, ISSN: 19457170 00137227

Woodruff; Lyon; Hansen; Glenn C. Rice; Mather

January 1, 1990

Radiofluorography: A method for rapid whole body autoradiography

Journal of Histotechnology, ISSN: 20460236 01478885

Hansen

January 1, 1990

GTP-binding Ypt1 protein and Ca2+ function independently in a cell-free protein transport reaction

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

David Baker; Wuestehube; Randy Schekman; David Botstein; Nava Segev

January 1, 1990

Comment: Duteplase not alteplase

DICP, Annals of Pharmacotherapy, ISSN: 10429611

Magnuson

January 1, 1990

Chemical Racemization of 5-Benzylhydantoin

Journal of Organic Chemistry, ISSN: 15206904 00223263

Lazarus

January 1, 1990

Human kidney amiloride-binding protein: CDNA structure and functional expression

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Pascal Barbry; Mark Champe; Olivier Chassande; Munemitsu; Guy Champigny; Eric Llngueglia; Pierrette Maes; Christian Frelin; André Tartar; Axel Ullrich; Michel Lazdunski

January 1, 1990

Molecular Recognition between Ligands and Nucleic Acids: Novel Pyridine- and Benzoxazole-Containing Agents Related to Hoechst 33258 that Exhibit Altered DNA Sequence Specificity Deduced from Footprinting Analysis and Spectroscopic Studies

Chemical Research in Toxicology, ISSN: 15205010 0893228X

Yadagiri Bathini; K. Ekambareswara Rao; J. William Lown; Regan G. Shea

January 1, 1990

Cell banking.

Bioprocess technology, ISSN: 08887470

Wiebe; May

January 1, 1990

A novel epithelial cell from neonatal rat lung: Isolation and differentiated phenotype

American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN: 00029513

Penelope E. Roberts; David M. Phillips; Mather

January 1, 1990

Role of hemostatic defect during thrombolytic therapy with recombinant tissue-type plasminogen activator

Thrombosis Research, ISSN: 00493848

David Stump

January 1, 1990

Interferons and collagen production

Journal of Investigative Dermatology, ISSN: 15231747 0022202X

Richard D. Granstein; Thomas J. Flotte; Edward P. Amento

January 1, 1990

Molecular cloning of the gene for the human placental GTP-binding protein Gp (G25K): Identification of this GTP-binding protein as the human homolog of the yeast cell-division-cycle protein CDC42

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Katsuhiro Shinjo; John G. Koland; Matthew J. Hart; Vikram Narasimhan; Douglas I. Johnson; Tony Evans; Richard A. Cerione

January 1, 1990

Presence and transcription of intracisternal A-particle-related sequences in CHO cells

Journal of Virology, ISSN: 0022538X

Anderson; Yolanda S. Lie; Mari-Anne L. Low; Steven R. Williams; Fennie; Nguyen; Florian M. Wurm

January 1, 1990

Assay requirements for cell culture process development.

Bioprocess technology, ISSN: 08887470

Mary B. Sliwkowski; Edward T. Cox

January 1, 1990

Crystal structure of an active form of RAS protein, a complex of a GTP analog and the HRAS p21 catalytic domain

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Axel T. Brünger; Michael V. Milburn; Liang Tong; Abraham M. Devos; Jarmila Jancarik; Ziro Yamaizumi; Susumu Nishimura; Eiko Ohtsuka; Sung-Hou Kim

January 1, 1990

Selective attraction of monocytes and T lymphocytes of the memory phenotype by cytokine RANTES

Nature, ISSN: 00280836

Thomas J. Schall; Bacon; Toy; David V. Goeddel

January 1, 1990

Soluble forms of herpes simplex virus glycoprotein D bind to a limited number of cell surface receptors and inhibit virus entry into cells

Journal of Virology, ISSN: 0022538X

David C. Johnson; Burke; Timothy Gregory

January 1, 1990

Zinc mediation of the binding of human growth hormone to the human prolactin receptor

Science, ISSN: 00368075

Cunningham; Bass; Fuh; James A. Wells

January 1, 1990

Requirement for activin a and transforming growth factor-β1 pro-regions in homodimer assembly

Science, ISSN: 00368075

Gray; Anthony J. Mason

January 1, 1990

The carboxy terminus of human immunodeficiency virus type 1 gp160 limits its proteolytic processing and transport in transfected cell lines

Journal of Virology, ISSN: 0022538X

Haffar; Nakamura; Berman

January 1, 1990

Chromosome instability mutants of Saccharomyces cerevisiae that are defective in microtubule-mediated processes

Molecular and Cellular Biology, ISSN: 02707306

M. Andrew Hoyt; Stearns; David Botstein

December 20, 1989

Enzyme-linked bio-immunoassay for IFN-γ by HLA-DR induction

Journal of Immunological Methods, ISSN: 00221759

Ursula E.M. Gibson; Susan M. Kramer

December 20, 1989

Purification of a ubiquitin protein peptidase from yeast with efficient in vitro assays

Journal of Biological Chemistry, ISSN: 00219258

Liu; Miller; William J. Kohr; Silber

December 1, 1989

Expression of recombinant platelet glycoprotein IIbIIIa results in a functional fibrinogen-binding complex

Journal of Biological Chemistry, ISSN: 00219258

Bodary; Napier; McLean

December 1, 1989

Expression, purification, and characterization of recombinant BP53, the GH-dependent IGF binding protein

Insuline-like Growth Factor binding proteins: proceedings of a workshop on Insuline-like Growth Factor binding proteins. ICS881,

Mukku; Courter; Gorman; Parker; Larsen; William I. Wood

December 1, 1989

Ectopic expression of interferon gamma and class II MHC induce the development of insulin-dependent diabetes mellitus in transgenic mice

Genes and gene products in the development of diabetes mellitus: proceedings of the 3rd Nordisk Insulin Symposium 'Genes ane gene products in the development of diabetes mellitus'. ICS866,

Sarvetnick; Liggitt; Stewart

December 1, 1989

Transgenic mice as a model to test the immunogenicity of proteins altered by site-specific mutagenesis

Molecular Biology and Medicine, ISSN: 07351313

Stewart; Hollingshead; Pitts; Chang; Martin; Oakley

November 15, 1989

Plasma desorption mapping of the tryptic digest of 23-kDa recombinant human growth hormone

Analytical Biochemistry, ISSN: 10960309 00032697

Ling Chen; Robert J. Cotter; Stults

November 1, 1989

Mutational analysis of the conserved domains of a T-region border repeat of Agrobacterium tumefaciens

Plant Molecular Biology, ISSN: 01674412 15735028

van Haaren; Sedee; Herman A. de Boer; Schilperoort; Hooykaas

November 1, 1989

Characterization of recombinant human lymphotoxin (tumor necrosis factor-β) produced by a mammalian cell line

Archives of Biochemistry and Biophysics, ISSN: 10960384 00039861

Hains; Aggarwal

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