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Publications

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DISPLAYING 101 - 150 OF 15664 RESULTS

Quantification of mRNA Using 31P NMR Spectroscopy and CRAFT
Magnetic Resonance in Chemistry, ISSN: 1097458X 07491581
Gennady Khirich; Vanessa A. Noreika; Kaitlyn Doolittle Catlin; José G. Napolitano; David J. Russell; Oliver Birkholz; Jens Schumacher; Heinrich Haas; Ken Skidmore
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Quantitative Structural and Compositional Elucidation of Real-World Pharmaceutical Tablet Using Large Field-of-View, Correlative Microscopy-Tomography Techniques and AI-Enabled Image Analysis
Pharmaceutical Research, ISSN: 1573904X 07248741
Yinshan Chen; Sruthika Baviriseaty; Prajwal Thool; Jonah Gautreau; Phillip D. Yawman; Kellie Sluga; Jonathan Hau; Shawn Zhang; Chen Mao
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2024 White Paper on Recent Issues in Bioanalysis: Evolution of Immunogenicity Assessment beyond ADA/NAb; Regulated Genomic/NGS Assays; Hypersensitivity Reactions; Minimum Noise Reduction; False Positive Range; Modernized Vaccine Approaches; NAb/TAb Correlation (PART 3A–Recommendations on Advanced Strategies for Molecular Assays and Immunogenicity of Gene Therapy, Cell Therapy, Vaccine; Biotherapeutics Immunogenicity Assessment & Clinical Relevance PART 3B–Regulatory Agencies’ Input on Immunogenicity/Technologies of Biotherapeutics, Gene, Cell & Vaccine Therapies)
Bioanalysis, ISSN: 17576199 17576180
Omar Tounekti; Sandra Prior; Sarah Wassmer; Joshua Xu; Adrian Wong; Xiaodong Fang; Ivo Sonderegger; John Smeraglia; James Huleatt; Lina Loo; Chris Beaver; Jason Delcarpini; Francis Dessy; Sandra Diebold; Michele Fiscella; Fabio Garofolo; Grimaldi; Swati Gupta; Victor Hou; Chad Irwin; Dewal Jani; Julie Joseph; Warren Kalina; Sumit Kar; Uma Kavita; Yanmei Lu; Jean-Claude Marshall; Christian Mayer; Johanna Mora; Katrina Nolan; Kun Peng; Nathan Riccitelli; Ingrid Scully; Jessica Seitzer; Mark Stern; Meenu Wadhwa; Yuanxin Xu; Verthelyi; Giane Sumner; Adrienne Clements-Egan; Cecil Chen; Boris Gorovits; Albert Torri; Daniel Baltrukonis; George R. Gunn; Akiko Ishii-Watabe; Daniel Kramer; Robert J Kubiak; Garrett Mullins; Luying Pan; Michael A. Partridge; Johann Poetzl; Michele Rasamoelisolo; Federico Riccardi Sirtori; Richards; Ola M. Saad; Weiping Shao; Yuan Song; Sam Song; Roland F Staack; Bonnie Wu; Mohanraj Manangeeswaran; Seth Thacker
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Correction to: Multiplexed, image-based pooled screens in primary cells and tissues with PerturbView (Nature Biotechnology, (2024), 10.1038/s41587-024-02391-0)
Nature Biotechnology, ISSN: 15461696 10870156
Takamasa Kudo; Ana M. Meireles; Reuben Moncada; Yushu Chen; Ping Wu; Joshua Gould; Xiaoyu Hu; Opher S. Kornfeld; Rajiv Jesudason; Conrad Foo; Burkhard Höckendorf; Hector Corrada Bravo; Jason P. Town; Runmin Wei; Antonio Rios; Vineethkrishna Chandrasekar; Melanie Heinlein; Amy S. Chuong; Shuangyi Cai; Cherry Sakura Lu; Paula Coelho; Monika Mis; Cemre Celen; Noelyn Kljavin; Jian Jiang; David Richmond; Pratiksha I. Thakore; Elia Benito-Gutiérrez; Kathryn R. Geiger-Schuller; Jose Sergio Hleap; Nobuhiko Kayagaki; Felipe de Sousa e Melo; Lisa M McGinnis; Bo Li; Avtar Singh; Levi A. Garraway; Orit Rozenblatt-Rosen; Aviv Regev; Eric Lubeck
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Type I Error Control of an Adaptive Endpoint Selection Procedure
Statistics in Biopharmaceutical Research, ISSN: 19466315
Nan Hu; Godwin Yung; Howard M. Mackey
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Venetoclax Combined With Chemotherapy in Pediatric and Adolescent/Young Adult Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia
Pediatric Blood and Cancer, ISSN: 15455017 15455009
Andrew E Place; Seth E. Karol; Christopher J. Forlenza; Todd M. Cooper; Christopher Fraser; Gunnar Cario; Maureen M. O'Brien; Nicolas U. Gerber; Jean-Pierre Bourquin; Dirk Reinhardt; Jeffrey E. Rubnitz; Joseph T. Opferman; Gauri Sunkersett; Maika Onishi; Diana Ronai Dunshee; Xin Chen; Kristina Unnebrink; Deeksha Vishwamitra; Fengjiao Dunbar; Mohamed Badawi; Jeremy A. Ross; Mignon L. Loh
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Autogene cevumeran with or without atezolizumab in advanced solid tumors: a phase 1 trial
Nature Medicine, ISSN: 1546170X 10788956
Juanita Lopez; Thomas Powles; Fadi S. Braiteh; Siu; Patricia M. LoRusso; Claire F Friedman; Ani Balmanoukian; Michael S. Gordon; Jeffrey Yachnin; Sylvie Rottey; Ioannis Karydis; George A. Fisher; Marcus Schmidt; Martin Schuler; Ryan J. Sullivan; Howard A. Burris; Vladimir Galvao; Brian S. Henick; Luc Dirix; Dirk Jaeger; Patrick A. Ott; Kit Man Wong; Guy Jerusalem; Aglaia Schiza; Lawrence Fong; Neeltje Steeghs; Rom S. Leidner; Achim Rittmeyer; Scott A. Laurie; Eelke Gort; Raid Aljumaily; Ignacio Melero; Rachel L. Sabado; Ina Rhee; Michael R. Mancuso; Lars Muller; Gregg D. Fine; Mahesh Yadav; Leesun Kim; Vincent J.P. Leveque; Alberto Hidalgo Robert; Martine Darwish; Ting Qi; Jiawen Zhu; Jingbin Zhang; Patrick S. Twomey; Gautham K. Rao; Donald W. Low; Chris Petry; Amy Lo; Jill Schartner; Lélia Delamarre; Ira Mellman; Martin Löwer; Felicitas Müller; Evelyna Derhovanessian; Andrea Cortini; Luisa Manning; Daniel Maurus; Sebastian Brachtendorf; Verena Lörks; Tana Omokoko; Eva Godehardt; Dirk Becker; Christine Hawner; Christine Wallrapp; Christian Albrecht; Christoph Kröner; Arbel D. Tadmor; Jan Diekmann; Mathias Vormehr; Anette Jork; Anna Paruzynski; Maren Lang; Jonathon Blake; Oliver Hennig; Andreas N. Kuhn; Ugur Sahin; Özlem Türeci; D. Ross Camidge
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Population Pharmacokinetics and Exposure-Response of Subcutaneous Atezolizumab in Patients With Non-Small Cell Lung Cancer
CPT: Pharmacometrics and Systems Pharmacology, ISSN: 21638306
Phyllis Chan; Stephanie N. Liu; Nathalie H. Gosselin; Zacharie Sauve; Mathilde Marchand; Alyse Lin; Luis A. Herráez-Baranda; James Zanghi; Shearer-Kang; Xiaoyan Liu; Benjamin Wu; Pascal Chanu
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Applying the 3Rs to urinalysis assessments in toxicity studies: refining procedures and adopting a case-by-case approach
Comparative Clinical Pathology, ISSN: 1618565X 16185641
Elisa Passini; Adedeji; Romalie Allen; Paul Baldrick; Jayati Basak; Lorraine Britton; Peter Cotton; Joanna Harding; Thomas Holmes; Nina Ljumanovic; Fiona McClure; Aidan McGuire; Liz McInnes; Helen Prior; Fiona Sewell
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A Highly Sensitive Immunoassay to Enable Quantification of a Nanobody-Based Imaging Agent in Human Serum
AAPS Journal, ISSN: 15507416
Sebastián Guelman; Catherine Huang; Kun Peng
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A single point mutation on FLT3L-Fc protein increases the risk of immunogenicity
Frontiers in Immunology, ISSN: 16643224
Dan Qin; Qui Phung; Patrick Wu; Zhaojun Yin; Sien Tam; Tran; Adel ElSohly; Joshua G. Gober; Zicheng Hu; Zhenru Zhou; Sivan Cohen; Dongping He; Travis W. Bainbridge; Christopher C. Kemball; Jonathan Zarzar; Alavattam Sreedhara; Nicole Stephens; Jérémie Decalf; Christine Moussion; Zhengmao Ye; Mercedesz Balazs; Yinyin Li
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1H, 13C and 15N backbone resonance assignment of the catalytic domain of human PTPN22
Biomolecular NMR Assignments, ISSN: 18742718
Bryan Martin; Michael W. Clarkson; Ping Wu; Paola Di Lello
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Venetoclax Alone or in Combination With Chemotherapy in Paediatric and Adolescent/Young Adult Patients With Relapsed/Refractory Acute Myeloid Leukaemia
Pediatric Blood and Cancer, ISSN: 15455009
Seth E. Karol; Seong Lin Khaw; C Michel Zwaan; Andre Baruchel; Henrique Bittencourt; Todd M. Cooper; Christian Flotho; Christopher Fraser; Christopher J. Forlenza; Kelly Goldsmith; Margaret E. Macy; Daniel A Morgenstern; Maureen M. O'Brien; Arnaud Petit; David S. Ziegler; Dirk Reinhardt; Joseph T. Opferman; Jeffrey E. Rubnitz; Maika Onishi; Diana Ronai Dunshee; Fengjiao Dunbar; Deeksha Vishwamitra; Jeremy A. Ross; Xin Chen; Kristina Unnebrink; Maja Kammerlander; Ahmed Hamed Salem; Tammy Palenski; Gauri Sunkersett; Andrew E Place
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Formulation Development for Antibody–Drug Conjugates
AAPS Advances in the Pharmaceutical Sciences Series, ISSN: 2210738X 22107371
Junyan A. Ji; Jun Liu; Y. John Wang
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HHV-6 and HHV-7 reactivation in allogeneic CAR-T cell therapy
Trends in Biotechnology, ISSN: 18793096 01677799
Hiu Tung Chow; Wenjing Li; Bin Yang; Friedrich von Wintzingerode; Qi Chen
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Maintaining driving vision after intravitreal anti-VEGF therapy in patients with neovascular AMD and diabetic macular edema: a plain language summary of publication
Therapeutic Advances in Ophthalmology,
Parisa Emami-Naeini; Vincent Garmo; Nick Boucher; Rusirini Fernando; Alicia R. Menezes
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An LC-MS/MS Multiplexed Method to Quantify 14 Sphingolipids in Human Cerebrospinal Fluid (CSF)
Methods in Molecular Biology, ISSN: 10643745
Yadira Perez Paramo; Rathna Veeramachaneni; Emily Parkhurst; Dawn Dufield; W Rodney Mathews; Veronica G. Anania
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Race and Vision Outcomes in Ranibizumab-Treated Participants With Diabetic Macular Edema: A Meta-Analysis
JAMA Ophthalmology, ISSN: 21686165
M. Ali Khan; Lauren Hill; Ivaylo Stoilov; Julia A. Haller
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Oncology Dose Optimization: Tailored Approaches to Different Molecular Classes
Clinical Pharmacology and Therapeutics, ISSN: 00099236
Jiawen Zhu; Amy Schroeder; Sabine Frank; Christophe Boetsch; Candice Jamois; Nastya Kassir; Koorosh Korfi; Elizabeth A. Punnoose; Vaze; Peter C. Trask; Pritti Gosai; Jane Fridlyand; Chunze Li
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Macular Atrophy-Related Observations in Eyes Treated with the Port Delivery System with Ranibizumab in the Archway Trial
Ophthalmology Retina,
Glenn J. Jaffe; Briana Cameron; Giulio Barteselli; Natalia F. Callaway; Cindy Skalak; John Choong; Shamika Gune
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Atezolizumab Plus Bevacizumab in Patients with Unresectable Hepatocellular Carcinoma: Real-World Experience From a US Community Oncology Network
Journal of Hepatocellular Carcinoma,
David Cosgrove; Ruoding Tan; Andrew J Osterland; Sairy Hernandez; Sarika Ogale; Sami Mahrus; John Murphy; Thomas Wilson; Gregory Patton; Arturo Loaiza-Bonilla; Amit G. Singal
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Learning Multi-cellular Representations of Single-Cell Transcriptomics Data Enables Characterization of Patient-Level Disease States
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), ISSN: 03029743
Tianyu Liu; Edward De Brouwer; Tony Kuo; Nathaniel Diamant; Alsu Missarova; Hanchen Wang; Minsheng Hao; Hector Corrada Bravo; Gabriele Scalia; Aviv Regev; Graham Heimberg
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Reply to Felix Melchior, Andreas Pircher, and Isabel Heidegger's Letter to the Editor re: Johann S. de Bono, Meng He, Chen Shi, et al. Final Overall Survival and Molecular Data Associated with Clinical Outcomes in Patients Receiving Ipatasertib and Abiraterone in the Phase 3 IPATential150 Trial. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2024.12.015
European Urology, ISSN: 03022838
Christopher J. Sweeney; Meng He; Matthew Wongchenko; Roberta Ferraldeschi; De Bono
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Development of a Broadly Applicable Enzymatic Ligation Process for the Production of Single Guide RNAs
Organic Process Research and Development, ISSN: 10836160
Martina Bigatti; André Moser; Bas Dierssen; Shtjefen Frrokaj; Elena Covato; Christophe Pfleger; Joerg Lill; Yael Leiser; Joël Zuber; Andreas Staempfli; Filippo Sladojevich; Stefan G. Koenig
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Plasma biomarker trajectories: Impact of AD genetic risk and clinical progression
Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring,
Corinne Pettigrew; Anja Soldan; Jiangxia Wang; Timothy Hohman; Logan Dumitrescu; Marilyn S. Albert; Kaj Blennow; Tobias Bittner; Abhay Moghekar
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Atezolizumab in High-Risk Locally Advanced Squamous Cell Carcinoma of the Head and Neck A Randomized Clinical Trial
JAMA - Journal of the American Medical Association, ISSN: 00987484
Haddad; Jérôme Fayette; Maria Teixeira; Kumar Prabhash; Ricard Mesia; Andrzej Kawecki; Arunee Dechaphunkul; José Dinis; Ye Guo; Muneyuki Masuda; Ching-Yun Hsieh; Maria Grazia Ghi; Claudia Vaz de Melo Sette; Kevin J. Harrington; Makoto Tahara; Nabil F. Saba; Agnes Lau; Tao Jiang; Yibing Yan; Ballinger; Kaul; Christina Matheny; Vaikunth Cuchelkar; Wong
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Atezolizumab plus bevacizumab and chemotherapy in metastatic nonsquamous NSCLC: the randomized double-blind phase 3 IMpower151 trial
Nature Medicine, ISSN: 10788956
Caicun Zhou; Xiaorong Dong; Gongyan Chen; Zhehai Wang; Xianghua Wu; Yu Yao; Yiping Zhang; Ying Cheng; Hongming Pan; Xiaodong Zhang; Jiuwei Cui; Lifeng Wang; Xi Chen; Xiaoling Li; Ziping Wang; Qiming Wang; Jianxing He; Mengzhao Wang; Iris Yan; Li Qian; Miao Xu; Xiayu Huang; Chun Sun; Jun Cai; Qiong Wu; Ballinger; Kaul; Srivastava
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Mechanistic Physiologically Based Pharmacokinetic Modeling of Dry Powder and Nebulized Formulations of Orally Inhaled TMEM16A Potentiator GDC-6988
CPT: Pharmacometrics and Systems Pharmacology,
Rui Zhu; Ian Sorrell; Fang Ma; Miaoran Ning; Yoen-Ju Son; Gaohong She; Tom De Bruyn; Joshua Galanter; Nastya Kassir; Ryan Owen; Masoud Jamei; Iain Gardner; Yuan Chen
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Mechanistic Characterization of the Potency of THIOMAB Antibody-Drug Conjugates Targeting Staphylococcus aureus and ETbR-Expressing Tumor Cells Using Quantitative LC-MS/MS Analysis of Intracellular Drug Accumulation
Bioconjugate Chemistry, ISSN: 10431802
Hilda Hernandez-Barry; Josefa Dela Cruz Chuh; Kimberly K. Kajihara; Jyoti Asundi; Richard L. Vandlen; Donglu Zhang; Wouter L. W. Hazenbos; Thomas H. Pillow; Yichin Liu; Cong Wu; Katherine R. Kozak; Kelly M. Loyet
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Use of Real-World Claims Data to Assess the Prevalence of Concomitant Medications to Inform Drug–Drug Interaction Risk in Target Patient Populations
Clinical Pharmacology and Therapeutics, ISSN: 00099236
Alice S. Tang; Logan Brooks; Denise M. Boudreau; Pascal Chanu; Amita Joshi; Bianca Vora; Rui Zhu
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Correction to: A multi-modal single-cell and spatial expression map of metastatic breast cancer biopsies across clinicopathological features (Nature Medicine, (2024), 30, 11, (3236-3249), 10.1038/s41591-024-03215-z)
Nature Medicine, ISSN: 10788956
Johanna Klughammer; Daniel L. Abravanel; Asa Segerstolpe; Timothy R. Blosser; Yury Goltsev; Yi Cui; Daniel R. Goodwin; Anubhav Sinha; Orr Ashenberg; Michal Slyper; Sébastien Vigneau; Judit Jané-Valbuena; Shahar Alon; Chiara Caraccio; Judy Chen; Ofir Cohen; Nicole Cullen; Laura DelloStritto; Danielle Dionne; Janet Files; Allison Frangieh; Karla Helvie; Melissa E. Hughes; Stephanie Inga; Abhay Kanodia; Ana Lako; Colin MacKichan; Mages; Noa Moriel; Evan Murray; Sara Napolitano; Kyleen Nguyen; Mor Nitzan; Rebecca Ortiz; Miraj Patel; Kathleen L. Pfaff; Caroline B. M. Porter; Asaf Rotem; Sarah Strauss; Robert Strasser; Aaron R. Thorner; Madison Turner; Isaac Wakiro; Julia Waldman; Jingyi Wu; Jorge Gómez Tejeda Zañudo; Diane Zhang; Lin; Tolaney; Eric P. Winer; Edward S. Boyden; Fei Chen; Garry P. Nolan; Scott J. Rodig; Xiaowei Zhuang; Orit Rozenblatt-Rosen; Bruce E. Johnson; Aviv Regev; Nikhil Wagle
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A Randomized Phase II Study of Efmarodocokin Alfa, an interleukin-22 Agonist, Versus Vedolizumab in Patients With Ulcerative Colitis
Clinical Gastroenterology and Hepatology, ISSN: 15423565
Silvio Danese; Michael E. Rothenberg; Jeremy J. Lim; Han Ting Ding; Jacqueline McBride; Yiling Chen; Ajit Dash; Jordan S. Mar; Mary E. Keir; Peyrin-Biroulet; Julián Panés; Jean-Frédéric Colombel; Brian G. Feagan; John F Valentine; Stefan Schreiber
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Integration of biobank-scale genetics and plasma proteomics reveals evidence for causal processes in asthma risk and heterogeneity
Cell Genomics,
Lauren J. Donoghue; Christian Benner; Diana Chang; Flaviyan J. Irudayanathan; Rion Pendergrass; Brian L. Yaspan; Anubha Mahajan; Mark I. McCarthy
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Optimization of Brain Penetrant SARM1 Orthosteric Inhibitors and Discovery of Their Paradoxical Subinhibitory Activation
ACS Medicinal Chemistry Letters,
Samantha A. Green; Russell T. Smith; Jessica M. Grandner; Mingshuo Zeng; Matthew Del Bel; Bing-Yan Zhu; Jun Liang; Marie-Gabrielle Braun; Jawahar Sudhamsu; Heidi J. A. Wallweber; Gladys de Leon Boenig; Jeremy Murray; Xiaoli Shen; Renwei Zhang; Kwong Wah Lai; Anton Delwig; Maria Andrea Breboneria; Justin Ly; Anjani Ganti; Marika Nespi; Martin Weber; Rebecca Leahey; Flora I. Hinz; Bryan K. Chan
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NRF2 supports non-small cell lung cancer growth independently of CBP/p300-enhanced glutathione synthesis
EMBO Reports, ISSN: 1469221X
Ryan J. Conrad; James A. Mondo; Mike Lingjue Wang; Peter S. Liu; Zijuan Lai; Feroza K. Choudhury; Qingling Li; Weng Wong; James Lee; Frances Shanahan; Eva Lin; Scott E. Martin; Joachim Rudolph; John Moffat; Dewakar Sangaraju; Wendy N. Sandoval; Tim Sterne-Weiler; Scott A. Foster
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Long-Term Safety and Efficacy of the Fixed-Dose Combination of Pertuzumab and Trastuzumab for Subcutaneous Injection in Patients With HER2-Positive Early Breast Cancer in PHranceSCa, a Randomized, Open-Label Phase II Study
Clinical Breast Cancer, ISSN: 15268209
O'Shaughnessy; Sousa; Josefina Cruz; Dame Lesley Fallowfield; Päivi Auvinen; Catarina Pulido; Ana Cvetanovic; Sharon Wilks; Leonor Ribeiro; Mauricio Burotto; Thomas Boulet; Revelant; Nathalie Theron; Peter C. Trask; Laurentia Wahyudi; Kirchmayer Machackova; Ljiljana Stamatovic
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Evaluating teratoma formation risk of pluripotent stem cell-derived cell therapy products: a consensus recommendation from the Health and Environmental Sciences Institute's International Cell Therapy Committee
Cytotherapy, ISSN: 14653249
Takeshi Watanabe; Shin La Shu; Alberto del Rio-Espinola; Joana Rita Ferreira; Kiyoko Bando; Myriam Lemmens; Parimal Pande; Charlotte de Wolf; Connie Chen; Ericson Elke; Gautham K. Rao; Tineke van den Hoorn; Lucilia Pereira Mouriès; Meagan B. Myers; Satoshi Yasuda
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Five-Year Survival Outcomes With Atezolizumab After Chemotherapy in Resected Stage IB-IIIA Non–Small Cell Lung Cancer (IMpower010): An Open-Label, Randomized, Phase III Trial
Journal of Clinical Oncology, ISSN: 0732183X
Enriqueta Felip; Nasser Altorki; Caicun Zhou; Eric Vallières; Tibor Csoszi; Ihor Vynnychenko; Oleksandr Goloborodko; Achim Rittmeyer; Martin Reck; Alex Martinez-Marti; Hirotsugu Kenmotsu; Yuh-Min Chen; Antonio Chella; Shunichi Sugawara; Chenqi Fu; Ballinger; Yu Deng; Srivastava; Elizabeth Bennett; Barbara Gitlitz; Heather A. Wakelee
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In-Line Raman Spectroscopy for Polymorph Monitoring During Continuous Crystallization
Applied Spectroscopy, ISSN: 00037028
Sreya Sarkar; Andreas Stumpf; Zhenqi Shi; Dawen Kou
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Self-amplifying NRF2–EZH2 epigenetic loop converts KRAS-initiated progenitors to invasive pancreatic cancer
Nature Cancer,
Laura Antonucci; Na Li; Angeles Duran; Isidoro Cobo; Chiara Nicoletti; Kosuke Watari; Shuvro Prokash Nandi; Feng Zhu; Yongmei Zhao; Irene Riahi; Motoyuki Tsuda; Vidhi M. Shah; Terry K. Morgan; Trent Waugh; Luca Caputo; Yuan Liu; Alexandra Rundberg Nilsson; Hongxu Xian; Jelena Todoric; Li Gu; Elsa Sanchez-Lopez; Guido Eibl; Emily A. Vucic; Michal Krawczyk; Qianlan Xu; Andrew M. Lowy; Georgia Hatzivassiliou; Merone Roose-Girma; Dorota Skowronska-Krawczyk; David A Scott; Dafna Bar-Sagi; Pablo Tamayo; Ying Wu; Rosalie C. Sears; Christopher K. Glass; Ludmil B. Alexandrov; Pier Lorenzo Puri; David W. Dawson; Yinling Hu; Maria T. Diaz-Meco; Jorge Moscat; Michael Karin
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Stereocontrolled First Generation Synthesis of RIPK1 Inhibitor GDC-8264
Organic Process Research and Development, ISSN: 10836160
Allen Y. Hong; Nicholas Wong; Sean M. Kelly; Lauren E. Sirois; Sara Schwegler; Xin Linghu; Carmela Molinaro; C. Gregory Sowell; Francis Gosselin
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Evaluation of low volume sampling devices for a pharmacodynamic biomarker analysis: Challenges and solutions
Journal of Pharmaceutical and Biomedical Analysis, ISSN: 07317085
Xiaoyun Yang; Evelin Logis; Kathi Williams; X Rebecca Sheng; Saloumeh Kadkhodayan Fischer
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How to build the virtual cell with artificial intelligence: Priorities and opportunities
Cell, ISSN: 10974172 00928674
Charlotte Bunne; Yusuf Roohani; Yanay Rosen; Ankit Gupta; Xikun Zhang; Marcel Roed; Theo Alexandrov; Mohammed AlQuraishi; Patricia Brennan; Daniel B. Burkhardt; Andrea Califano; Jonah Cool; Abby F. Dernburg; Kirsty Ewing; Emily B. Fox; Matthias Haury; Amy E. Herr; Eric Horvitz; Patrick D. Hsu; Viren Jain; Gregory R. Johnson; Thomas Kalil; David R. Kelley; Shana O. Kelley; Anna Kreshuk; Tim Mitchison; Stephani Otte; Jay Shendure; Nicholas J. Sofroniew; Fabian J. Theis; Christina V. Theodoris; Srigokul Upadhyayula; Marc Valer; Bo Wang; Eric Xing; Serena Yeung-Levy; Marinka Zitnik; Theofanis Karaletsos; Aviv Regev; Emma Lundberg; Jure Leskovec; Stephen Quake
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Molecular heterogeneity in urothelial carcinoma and determinants of clinical benefit to PD-L1 blockade
Cancer Cell, ISSN: 18783686 15356108
Habib Hamidi; Yasin Senbabaoglu; Niha Beig; Juliette Roels; Cyrus Manuel; Xiangnan Guan; Koeppen; Zoe June Assaf; Barzin Y. Nabet; Adrian Waddell; Kobe Yuen; Sophia L. Maund; Ethan S. Sokol; Jennifer M. Giltnane; Amber Schedlbauer; Eloisa Fuentes; James D. Cowan; Edward E. Kadel III; Viraj Degaonkar; Alexander Andreev-Drakhlin; Patrick Williams; Corey A. Carter; Suyasha Gupta; Elizabeth E. Steinberg; Yohann Loriot; Joaquim Bellmunt; Petros Grivas; Jonathan E. Rosenberg; Michiel S Van Der Heijden; Matthew D. Galsky; Thomas Powles; Sanjeev Mariathasan; Romain Banchereau
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Reactive oxygen species control protein degradation at the mitochondrial import gate
Molecular Cell, ISSN: 10974164 10972765
Rachael McMinimy; Andrew G. Manford; Christine L. Gee; Srividya Chandrasekhar; Gergey Alzaem Mousa; Joelle Chuang; Lilian Phu; Karen Y. Shih; Christopher M. Rose; John Kuriyan; Baris Bingol; Michael Rape
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Clinically Meaningful Change Estimates for the National Eye Institute Visual Function Questionnaire-25 in Patients With Diabetic Macular Edema
Translational Vision Science and Technology, ISSN: 21642591
Neil M. Bressler; Zdenka Haskova; Audrey Kapre; Brittany Gentile
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Advancing the role of real-world evidence in comparative effectiveness research
Journal of Comparative Effectiveness Research, ISSN: 20426313 20426305
Monica Daigl; Seye Abogunrin; Felipe Castro; Sarah F. McGough; Rachele Hendricks Sturrup; Cornelis Boersma; Keith R. Abrams
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Evaluating the effect of injection protocols on intrathecal solute dispersion in non-human primates: an in vitro study using a cynomolgus cerebrospinal fluid system
Fluids and Barriers of the CNS,
Goutham Kumar Reddy Burla; Dev Shrestha; Mayumi Bowen; Joshua Horvath; Bryn A. Martin
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The impact of antifibrotic use on long-term clinical outcomes in the pulmonary fibrosis foundation registry
Respiratory Research, ISSN: 14659921
Cathryn T. Lee; Wei Hao; Cindy Burg; Jennie Best; Giselle E. Kolenic; Mary E. Strek
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Single-cell long-read targeted sequencing reveals transcriptional variation in ovarian cancer
Nature Communications,
Ashley Byrne; Daniel Le; Kostianna Sereti; Hari Menon; Samir Vaidya; Neha Patel; Jessica Lund; Ana Xavier-Magalhães; Minyi Shi; Yuxin Liang; Tim Sterne-Weiler; Zora Modrusan; William Stephenson
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