Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 2951 - 3000 OF 15169 RESULTS

Correlations between surface composition and aerosolization of jet-milled dry powder inhaler formulations with pharmaceutical lubricants
International Journal of Pharmaceutics, ISSN: 18733476 03785173
Sharad Mangal; Heejun Park; Reham Nour; Nivedita Shetty; Alex Cavallaro; Dmitry Zemlyanov; Kyrre Thalberg; Vibha Puri; Mark Nicholas; Ajit S. Narang; Qi (Tony) Zhou
View on Scopus
Identification of an acetonitrile addition impurity formed during peptide disulfide bond reduction using dithiothreitol and Tris(2-carboxyethyl)phosphine
Journal of Pharmaceutical and Biomedical Analysis, ISSN: 1873264X 07317085
Eileen X. Zhao; Frederic St-Jean; Sarah J. Robinson; Lauren E. Sirois; Jackson D. Pellett; Mohammad Al-Sayah
View on Scopus
Establishment of neurofilament light chain Simoa assay in cerebrospinal fluid and blood
Bioanalysis, ISSN: 17576199 17576180
Robert Hendricks; Baker; Jochen Brumm; Teresa Davancaze; Chris Harp; Ann E. Herman; H-Christian von Büdingen; Michael J. Townsend; Saloumeh Kadkhodayan Fischer
View on Scopus
GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI
Science Advances, ISSN: 23752548
Alexessander Couto Alves; N. Maneka G. De Silva; Ville Karhunen; Ulla Sovio; Shikta Das; Rob Taal; Nicole M. Warrington; Alexandra M. Lewin; Marika Kaakinen; Diana L. Cousminer; Elisabeth Thiering; Nicholas J. Timpson; Tom A. Bond; Estelle Lowry; Christopher D. Brown; Xavier Estivill; Virpi Lindi; Jonathan P. Bradfield; Frank Geller; Doug Speed; Lachlan Coin; Marie Loh; Sheila J. Barton; Lawrence J. Beilin; Hans Bisgaard; Klaus Bønnelykke; Rohia Alili; Ida J. Hatoum; Katharina Schramm; Rufus Cartwright; Marie-Aline Charles; Vincenzo Salerno; Karine Clément; Annique A.J. Claringbould; Cornelia M. Van Duijn; Elena Moltchanova; Johan G. Eriksson; Cathy Elks; Bjarke Feenstra; Claudia Flexeder; Stephen Franks; Timothy M. Frayling; Rachel M. Freathy; Paul Elliott; Elisabeth Widén; Hakon Hakonarson; Andrew T. Hattersley; Alina Rodriguez; Marco Banterle; Joachim Heinrich; Barbara Heude; John W. Holloway; Albert Hofman; Elina Hyppönen; Hazel Inskip; Lee M. Kaplan; Åsa Hedman; Esa Läärä; Holger Prokisch; Harald Grallert; Timo A. Lakka; Debbie A. Lawlor; Mads Melbye; Tarunveer S. Ahluwalia; Marcella Marinelli; Iona Y Millwood; Lyle J. Palmer; Craig E. Pennell; John R. Perry; Susan M. Ring; Markku J. Savolainen; Fernando Rivadeneira; Marie Standl; Jordi Sunyer; Carla M.T. Tiesler; André G. Uitterlinden; William Schierding; O'Justin M. Sullivan; Inga Prokopenko; Karl-Heinz Herzig; George Davey Smith; Paul O'Reilly; Janine F. Felix; Jessica L. Buxton; Alexandra I. F. Blakemore; Ken K. Ong; Vincent W.V. Jaddoe; Struan F.A. Grant; Sylvain Sebert; Mark I. McCarthy; Marjo-Riitta Järvelin
View on Scopus
GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI
Science Advances, ISSN: 23752548
Alexessander Couto Alves; N. Maneka G. De Silva; Ville Karhunen; Ulla Sovio; Shikta Das; Rob Taal; Nicole M. Warrington; Alexandra M. Lewin; Marika Kaakinen; Diana L. Cousminer; Elisabeth Thiering; Nicholas J. Timpson; Tom A. Bond; Estelle Lowry; Christopher D. Brown; Xavier Estivill; Virpi Lindi; Jonathan P. Bradfield; Frank Geller; Doug Speed; Lachlan Coin; Marie Loh; Sheila J. Barton; Lawrence J. Beilin; Hans Bisgaard; Klaus Bønnelykke; Rohia Alili; Ida J. Hatoum; Katharina Schramm; Rufus Cartwright; Marie-Aline Charles; Vincenzo Salerno; Karine Clément; Annique A.J. Claringbould; Cornelia M. Van Duijn; Elena Moltchanova; Johan G. Eriksson; Cathy Elks; Bjarke Feenstra; Claudia Flexeder; Stephen Franks; Timothy M. Frayling; Rachel M. Freathy; Paul Elliott; Elisabeth Widén; Hakon Hakonarson; Andrew T. Hattersley; Alina Rodriguez; Marco Banterle; Joachim Heinrich; Barbara Heude; John W. Holloway; Albert Hofman; Elina Hyppönen; Hazel Inskip; Lee M. Kaplan; Åsa Hedman; Esa Läärä; Holger Prokisch; Harald Grallert; Timo A. Lakka; Debbie A. Lawlor; Mads Melbye; Tarunveer S. Ahluwalia; Marcella Marinelli; Iona Y Millwood; Lyle J. Palmer; Craig E. Pennell; John R. Perry; Susan M. Ring; Markku J. Savolainen; Fernando Rivadeneira; Marie Standl; Jordi Sunyer; Carla M.T. Tiesler; Clive Holmes; William Schierding; O'Justin M. Sullivan; Inga Prokopenko; Karl-Heinz Herzig; George Davey Smith; Paul O'Reilly; Janine F. Felix; Jessica L. Buxton; Alexandra I. F. Blakemore; Ken K. Ong; Vincent W.V. Jaddoe; Struan F.A. Grant; Sylvain Sebert; Mark I. McCarthy; Marjo-Riitta Järvelin
View on Scopus
Function of CSF1 and IL34 in Macrophage Homeostasis, Inflammation, and Cancer
Frontiers in Immunology, ISSN: 16643224
Wei Yu Lin; Daqi Xu; Cary D. Austin; Patrick Caplazi; Kate Senger; Yonglian Sun; Surinc Er Jeet; Judy Young; Donnie Delarosa; Eric Suto; Zhiyu Huang; Juan Zhang; Donghong Yan; Cesar A. Corzo; Kai H. Barck; Sharmila Rajan; Looney; Vineela D. Gandham; Justin Lesch; Wei-Ching Liang; Elaine Mai; Hai Ngu; Navneet Ratti; Yongmei Chen; Misner; Tori Lin; Dimitry Danilenko; Paula Katavolos; Estelle Doudemont; Hirdesh Uppal; Jeffrey Eastham; Judy Mak; Patricia De Almeida; Katherine Bao; Azadeh Hadadianpour; Mary E. Keir; Richard A. D. Carano; Laurie Diehl; Min Xu; Yan Wu; Robby M. Weimer; Jason Devoss; Wyne P. Lee; Mercedesz Balazs; Kevin B. Walsh; Kathila R. Alatsis; Flavius Martin; Ali A. Zarrin
View on Scopus
CD3 bispecific antibody-induced cytokine release is dispensable for cytotoxic T cell activity
Science Translational Medicine, ISSN: 19466242 19466234
Ji Li; Robert Piskol; Ryan Ybarra; Ying-Jiun J. Chen; Jason Li; Dionysos S. Slaga; Maria Hristopoulos; Robyn Clark; Zora Modrusan; Klara Totpal; Melissa Junttila; Teemu T. Junttila
View on Scopus
Preclinical assessment of the ADME, efficacy and drug-drug interaction potential of a novel NAMPT inhibitor
Xenobiotica, ISSN: 13665928 00498254
Bianca M. Liederer; Jonathan Cheong; Kang-Jye Chou; Peter Dragovich; Hoa Le; Xiaorong Liang; Justin Ly; Sophie Mukadam; Jason Oeh; Deepak Sampath; Leslie Wang; Susan C. Wong
View on Scopus
Inclusion of telemetry cardiovascular parameters in small molecule repeat-dose toxicity studies, a potential refinement in animal use
Journal of Pharmacological and Toxicological Methods, ISSN: 1873488X
Dale Stevens; Lisa P. Wong; Leah Schutt; Thomas R. Gelzleichter
View on Scopus
Retrospective Evaluation of Cycled Resin in Viral Clearance Studies-A Multiple Company Collaboration
PDA Journal of Pharmaceutical Science and Technology, ISSN: 19482124
John Mattila; Sherrie Curtis; Yenny Webb-Vargas; Eileen Wilson; Olga Galperina; David Roush; Scott A. Tobler; Bradford Stanley; Mike Clark; Justin Weaver; Jeremy Pike; Deqiang Yu; Xinfang Li; Andreas Flicker; Johanna Kindermann; Norbert Schuelke; Richard Whitcombe; Louise Bennett
View on Scopus
Vapor-Phase Hydrogen Peroxide Uptake by Silicone Tubing and Primary Packaging Components during Protein Drug Product Aseptic Filling: Impact of Pretreatment and Sterilization Process
PDA Journal of Pharmaceutical Science and Technology, ISSN: 19482124
Devon Roshan Eisner; Aaron Hubbard; Kirk Eppler; Vassia Tegoulia; Maa
View on Scopus
Characterization of the Ontogeny of Hepatic UDP-Glucuronosyltransferase Enzymes Based on Glucuronidation Activity Measured in Human Liver Microsomes
Journal of Clinical Pharmacology, ISSN: 15524604 00912700
Justine Badée; Nahong Qiu; Abby C. Collier; Ryan Takahashi; William F. Forrest; Neil Parrott; Stephan Schmidt; Stephen Fowler
View on Scopus
Reply to S. Sorscher
Journal of Clinical Oncology, ISSN: 15277755 0732183X
Federico Innocenti; Fang-Shu Ou; Xueping Qu; Tyler J. Zemla; Donna Niedzwiecki; Rachel Tam; Shilpi Mahajan; Richard M. Goldberg; Monica M. Bertagnolli; Charles D. Blanke; Hanna Sanoff; James Atkins; Blase Polite; Alan P. Venook; Heinz-Josef Lenz; Omar Kabbarah
View on Scopus
Neoadjuvant trastuzumab emtansine and pertuzumab in human epidermal growth factor receptor 2–positive breast cancer: Three-year outcomes from the phase III KristinE study
Journal of Clinical Oncology, ISSN: 15277755 0732183X
Sara A. Hurvitz; Miguel Martín; Kyung Hae Jung; Chiun-Sheng Huang; Nadia Harbeck; Vicente Valero; Daniil Stroyakovskiy; Hans Wildiers; Mario Campone; Jean-François Boileau; Peter A. Fasching; Karen Afenjar; Gonzalo Spera; Vanesa Lopez-Valverde; Chunyan Song; Peter C. Trask; Thomas Boulet; Joseph Sparano; W Fraser Symmans; Alastair M. Thompson; Dennis J. Slamon
View on Scopus
An Nfil3–Zeb2–Id2 pathway imposes Irf8 enhancer switching during cDC1 development
Nature Immunology, ISSN: 15292916 15292908
Prachi Bagadia; Xiao Huang; Tian-Tian Liu; Vivek Durai; Gary E. Grajales-Reyes; Maximilian Nitschke; Zora Modrusan; Jeffrey M. Granja; Ansuman T. Satpathy; Carlos G. Briseño; Marco Gargaro; Arifumi Iwata; Sunkyung Kim; Howard Y. Chang; Andrey S. Shaw; Theresa L. Murphy; Kenneth M. Murphy
View on Scopus
Toward a Consensus on Applying Quantitative Liquid Chromatography-Tandem Mass Spectrometry Proteomics in Translational Pharmacology Research: A White Paper
Clinical Pharmacology and Therapeutics, ISSN: 15326535 00099236
Bhagwat Prasad; Brahim Achour; Per Artursson; Cornelis E. Hop; Yurong Lai; Philip C. Smith; Jill Barber; Jacek R. Wiśniewski; Spellman; Yasuo Uchida; Michael A. Zientek; Jashvant D. Unadkat; Amin Rostami-Hodjegan
View on Scopus
Recommendations for the Design of Clinical Drug–Drug Interaction Studies With Itraconazole Using a Mechanistic Physiologically-Based Pharmacokinetic Model
CPT: Pharmacometrics and Systems Pharmacology, ISSN: 21638306
Yuan Chen; Tamara D. Cabalu; Ernesto Callegari; Heidi J. Einolf; Lichuan Liu; Neil Parrott; Peters; Edgar Schuck; Pradeep Sharma; Helen Tracey; Vijay V. Upreti; Ming Zheng; Andy Z.X. Zhu; Stephen D. Hall
View on Scopus
Neoadjuvant letrozole plus taselisib versus letrozole plus placebo in postmenopausal women with oestrogen receptor-positive, HER2-negative, early-stage breast cancer (LORELEI): a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial
The Lancet Oncology, ISSN: 14745488 14702045
Saura; Dominik Hlauschek; Oliveira; Zardavas; Jallitsch-Halper; Lorena de la Peña; Nuciforo; Alberto Ballestrero; Dubsky; Janine M Lombard; Peter Vuylsteke; Carlos A Castaneda; Colleoni; Giuliano Santos Borges; Eva Ciruelos; Monica Fornier; Katalin Boer; Aditya Bardia; Wilson; Thomas J. Stout; Jerry Y. Hsu; Yi Shi; Martine Piccart; Michael Gnant; Baselga; Evandro De Azambuja
View on Scopus
Relocation of study participants for rare and ultra-rare disease trials: Ethics and operations
Contemporary Clinical Trials, ISSN: 15592030 15517144
Luke Gelinas; Brian Crawford; Ariella Kelman; Barbara E. Bierer
View on Scopus
Correction to: Safety, Tolerability, and Pharmacokinetics of GDC-0276, a Novel NaV1.7 Inhibitor, in a First-in-Human, Single- and Multiple-Dose Study in Healthy Volunteers (Clinical Drug Investigation, (2019), 39, 9, (873-887), 10.1007/s40261-019-00807-3)
Clinical Drug Investigation, ISSN: 11791918 11732563
Michael E. Rothenberg; Tagen; Jae H. Chang; Janel Boyce-Rustay; Michel Friesenhahn; David Hackos; Avis Hains; Daniel P. Sutherlin; Michael Ward; William Cho
View on Scopus
Immune profiles in primary squamous cell carcinoma of the head and neck
Oral Oncology, ISSN: 18790593 13688375
Vassiliki Saloura; Evgeny Izumchenko; Zhixiang Zuo; Bao; Michael Korzinkin; Ivan Ozerov; Alex Zhavoronkov; Sidransky; Atul Bedi; Mohammad O. Hoque; Koeppen; Michaela K. Keck; Arun Khattri; London; Nikita Kotlov; Fatima; Theodore Vougiouklakis; Yusuke Nakamura; Mark Lingen; Nishant Agrawal; Peter A. Savage; Stephen Kron; Justin Kline; Marcin Kowanetz; Tanguy Y. Seiwert
View on Scopus
[18F]GTP1 (Genentech Tau Probe 1), a radioligand for detecting neurofibrillary tangle tau pathology in Alzheimer’s disease
European Journal of Nuclear Medicine and Molecular Imaging, ISSN: 16197089 16197070
Sandra M. Sanabria-Bohorquez; Jan Marik; Annie Ogasawara; Jeff N. Tinianow; Herman S. Gill; Olivier Barret; Gilles D. Tamagnan; David Alagille; Gai Ayalon; Paul T. Manser; Thomas Bengtsson; Michael Ward; Simon P. Williams; Geoffrey A. Kerchner; John P. Seibyl; Ken Marek; Robby M. Weimer
View on Scopus
Cross-sectional associations between [18F]GTP1 tau PET and cognition in Alzheimer's disease
Neurobiology of Aging, ISSN: 15581497 01974580
Edmond Teng; Michael Ward; Paul T. Manser; Sandra M. Sanabria-Bohorquez; Rebecca D. Ray; Kristin R. Wildsmith; Suzanne Baker; Geoffrey A. Kerchner; Robby M. Weimer
View on Scopus
Safety analysis of rFVIIa with emicizumab dosing in congenital hemophilia A with inhibitors: Experience from the HAVEN clinical program
Journal of Thrombosis and Haemostasis, ISSN: 15387836 15387933
Gallia Levy; Elina Asikanius; Peter Kuebler; Soraya Benchikh El Fegoun; Sille Esbjerg; Stephanie Seremetis
View on Scopus
Safety, Tolerability, and Pharmacokinetics of GDC-0276, a Novel NaV1.7 Inhibitor, in a First-in-Human, Single- and Multiple-Dose Study in Healthy Volunteers
Clinical Drug Investigation, ISSN: 11791918 11732563
Michael E. Rothenberg; Tagen; Jae H. Chang; Janel Boyce-Rustay; Michel Friesenhahn; David Hackos; Avis Hains; Daniel P. Sutherlin; Michael Ward; William Cho
View on Scopus
Pharmacokinetic and exposure–response analysis of pertuzumab in patients with HER2-positive metastatic gastric or gastroesophageal junction cancer
Cancer Chemotherapy and Pharmacology, ISSN: 14320843 03445704
Whitney P. Kirschbrown; Wang; Ihsan Nijem; Atsushi Ohtsu; Paulo M. Hoff; Manish A. Shah; Lin Shen; Yoon-Koo Kang; Maria Alsina; Sandhya Girish; Amit Garg
View on Scopus
Prediction of Human Pharmacokinetics of Antibody–Drug Conjugates From Nonclinical Data
Clinical and Translational Science, ISSN: 17528062 17528054
Chunze Li; Cindy Zhang; Rong Deng; Douglas Leipold; Dongwei Li; Brandon Latifi; Yuying Gao; Crystal Zhang; Zao Li; Dale Miles; Shang-Chiung Chen; Divya Samineni; Wang; Priya Agarwal; Dan Lu; Saileta Prabhu; Sandhya Girish; Amrita Kamath
View on Scopus
Impact of omalizumab on patient-reported outcomes in chronic idiopathic urticaria: Results from a randomized study (XTEND-CIU)
Journal of Allergy and Clinical Immunology: In Practice, ISSN: 22132198
Thomas B. Casale; Thomas R. Murphy; Michael Holden; Yamina Rajput; Bongin Yoo; Jonathan A. Bernstein
View on Scopus
A Rapid High-Sensitivity Reversed–Phase Ultra High Performance Liquid Chromatography Mass Spectrometry Method for Assessing Polysorbate 20 Degradation in Protein Therapeutics
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Ying Cheng; Mark Hu; Camellia Zamiri; Toshiro Carcelen; Barthélemy Demeule; Anthony Tomlinson; Jie Gu; Yinges Yigzaw; Matt S. Kalo; X. Christopher Yu
View on Scopus
Long-term safety and effectiveness of tocilizumab in patients with rheumatoid arthritis and inadequate responses to csDMARDs and/or TNF inhibitors: an open-label study close to clinical practice
Clinical Rheumatology, ISSN: 14349949 07703198
Vivian P. Bykerk; Ostor; José Alvaro-Gracia; Karel Pavelka; José Andrés Román Ivorra; Michael T. Nurmohamed; Yves Luder; Paris N. M. Sidiropoulos; Jenny Devenport; Jean Sibilia
View on Scopus
Rituximab dosing in hematological malignancies: an old question, revisited
Cancer Chemotherapy and Pharmacology, ISSN: 14320843 03445704
Peter N. Morcos; Axel Boehnke; Nancy Valente; Donald E. Mager
View on Scopus
Cost of Disease Progression in Patients with Chronic Lymphocytic Leukemia, Acute Myeloid Leukemia, and Non-Hodgkin's Lymphoma
Oncologist, ISSN: 1549490X 10837159
Carolina Reyes; Nicole M. Engel-Nitz; Stacey Dacosta Byfield; Arliene Ravelo; Sarika Ogale; Tim Bancroft; Amy Anderson; May Chen; Matthew Matasar
View on Scopus
Cost of Disease Progression in Patients with Metastatic Breast, Lung, and Colorectal Cancer
Oncologist, ISSN: 1549490X 10837159
Carolina Reyes; Nicole M. Engel-Nitz; Stacey Dacosta Byfield; Arliene Ravelo; Sarika Ogale; Tim Bancroft; Amy Anderson; May Chen; Matthew Matasar
View on Scopus
RIPK3 Activation Leads to Cytokine Synthesis that Continues after Loss of Cell Membrane Integrity
Cell Reports, ISSN: 22111247
Susana Orozco; Brian P. Daniels; Nader Yatim; Michelle N. Messmer; Giovanni Quarato; Haiyin Chen-Harris; Sean P. Cullen; Annelise G. Snyder; Ralli-Jain; Sharon Frase; Stephen W.G. Tait; Douglas R. Green; Matthew L. Albert; Andrew Oberst
View on Scopus
Molecular Portraits of Early Rheumatoid Arthritis Identify Clinical and Treatment Response Phenotypes
Cell Reports, ISSN: 22111247
Myles J. Lewis; Michael R. Barnes; Blighe; Katriona Goldmann; Sharmila Rana; Jason A. Hackney; Nandhini Ramamoorthi; Christopher R. John; David S. Watson; Sarah K. Kummerfeld; Rebecca Hands; Sudeh Riahi; Vidalba Rocher-Ros; Felice Rivellese; Frances Humby; Stephen Kelly; Michele Bombardieri; Nora Ng; Maria Dicicco; Desirée Van Der Heijde; Robert Landewé; Annette H. M. Van Der Helm-van Mil; Alberto Cauli; McInnes; Christopher D. Buckley; Ernest Choy; Taylor; Michael J. Townsend; Costantino Pitzalis
View on Scopus
Complement C3 Is Activated in Human AD Brain and Is Required for Neurodegeneration in Mouse Models of Amyloidosis and Tauopathy
Cell Reports, ISSN: 22111247
Tiffany Wu; Borislav Dejanovic; Vineela D. Gandham; Alvin Gogineni; Rose Edmonds; Stephen P. Schauer; Karpagam Srinivasan; Melanie A. Huntley; Yuanyuan Wang; Tzu-Ming Wang; Maj Hedehus; Kai H. Barck; Maya Stark; Hai Ngu; Oded Foreman; William J. Meilandt; Justin Elstrott; Michael C. Chang; David V. Hansen; Richard A. D. Carano; Morgan Sheng; Jesse E. Hanson
View on Scopus
Validation of diagnosis codes to identify side of colon in an electronic health record registry
BMC Medical Research Methodology, ISSN: 14712288
Patricia Luhn; Deborah Kuk; Gillis Carrigan; Nathan Nussbaum; Rachael Sorg; Rebecca Rohrer; Melisa Tucker; Brandon Arnieri; Michael D. Taylor; Neal J. Meropol
View on Scopus
Tetravalent biepitopic targeting enables intrinsic antibody agonism of tumor necrosis factor receptor superfamily members
mAbs, ISSN: 19420870 19420862
Yanli Yang; Sherry Yeh; Shravan Madireddi; Wadim L. Matochko; Chen Gu; Patricia Pacheco-Sanchez; Ultsch; Gladys De Leon Boenig; Seth F. Harris; Brandon Leonard; Suzie J. Scales; Jing W. Zhu; Erin Christensen; Julie Qi Hang; Randall J. Brezski; Scot A. Marsters; Avi Ashkenazi; Siddharth Sukumaran; Chiu; Rafael Cubas; Kim; Greg A. Lazar
View on Scopus
Preclinical and translational pharmacokinetics of a novel THIOMAB™ antibody-antibiotic conjugate against Staphylococcus aureus
mAbs, ISSN: 19420870 19420862
Rong Deng; Chenguang Zhou; Dongwei Li; Hao Cai; Siddharth Sukumaran; Montserrat Carrasco-Triguero; Ola M. Saad; Denise Nazzal; Christopher Lowe; Ramanujan; Amrita Kamath
View on Scopus
Production, characterization, and in vivo half-life extension of polymeric IgA molecules in mice
mAbs, ISSN: 19420870 19420862
T. Noelle Lombana; Sharmila Rajan; Julie A. Zorn; Danielle Mandikian; Eugene C. Chen; Alberto Estevez; Victor Yip; Daniel D. Bravo; Wilson Phung; Farzam Farahi; Sharon Viajar; Sophia Lee; Avinash Gill; Wendy N. Sandoval; Jianyong Wang; Claudio Ciferri; C. Andrew Boswell; Marissa L. Matsumoto; Christoph Spiess
View on Scopus
BBDFA: A Practical Reagent for Trifluoromethylation of Allylic and Benzylic Alcohols on Preparative Scale
Organic Process Research and Development, ISSN: 1520586X 10836160
Chong Han; Lady Mae Alabanza; Sean M. Kelly; Douglas L. Orsi; Francis Gosselin; Ryan A. Altman
View on Scopus
Evaluating the quality of the 1000 genomes project data
BMC Genomics, ISSN: 14712164
Saurabh Belsare; Michal Levy-Sakin; Yulia Mostovoy; Durinck; Subhra Chaudhuri; Ming Xiao; Andrew S. Peterson; Pui-Yan Kwok; Somasekar Seshagiri; Jeffrey D. Wall
View on Scopus
Discovery of a C-8 hydroxychromene as a potent degrader of estrogen receptor alpha with improved rat oral exposure over GDC-0927
Bioorganic and Medicinal Chemistry Letters, ISSN: 14643405 0960894X
Sharada Labadie; Jun Li; Robert A. Blake; Jae H. Chang; Simon Goodacre; Steven J. Hartman; Weiling Liang; James R. Kiefer; Tracy L. Kleinheinz; Tommy Lai; Jiangpeng Liao; Daniel F. Ortwine; Vidhi Mody; Nicholas C. Ray; Fabien Roussel; Maia Vinogradova; Siew Kuen Yeap; Birong Zhang; Xiaoping Zheng; Jason R. Zbieg; Jun Liang; Xiaojing Wang
View on Scopus
Design of a brain-penetrant CDK4/6 inhibitor for glioblastoma
Bioorganic and Medicinal Chemistry Letters, ISSN: 14643405 0960894X
Sarah M. Bronner; Karl A. Merrick; Jeremy Murray; Laurent Salphati; John Moffat; Jodie Pang; Chris J. Sneeringer; Nicholas A. Dompe; Patrick Cyr; Hans E. Purkey; Gladys de Leon Boenig; Jun Li; Aleksandr Kolesnikov; Larouche-Gauthier; Kwong Wah Lai; Xiaoli Shen; Samuel Aubert-Nicol; Yi-Chen Chen; Jonathan Cheong; James J. Crawford; Marc Hafner; Pouyan Haghshenas; Araz Jakalian; Jean-Philippe Leclerc; Ngiap-Kie Lim; Thomas O'Brien; Emile G. Plise; Shalan; Claudio Sturino; John Wai; Yang Xiao; Jianping Yin; Zhao; Stephen Gould; Alan G. Olivero; Timothy P. Heffron
View on Scopus
Linking aggregation and interfacial properties in monoclonal antibody-surfactant formulations
Journal of Colloid and Interface Science, ISSN: 10957103 00219797
Aadithya Kannan; Ian C. Shieh; Gerald G. Fuller
View on Scopus
Safety Considerations in the Development of Hippo Pathway Inhibitors in Cancers
Frontiers in Cell and Developmental Biology, ISSN: 2296634X
Satoko Kakiuchi-Kiyota; Melissa Schutten; Yu Zhong; James J. Crawford; Anwesha Dey
View on Scopus
Disruption of IRE1α through its kinase domain attenuates multiple myeloma
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 10916490 00278424
Jonathan M. Harnoss; Adrien Le Thomas; Anna Shemorry; Scot A. Marsters; David Lawrence; Min Lu; Yung-Chia Ariel Chen; Jing Qing; Klara Totpal; David Kan; Ehud Segal; Mark Merchant; Mike Reichelt; Heidi J. A. Wallweber; Weiru Wang; Clark; Susan Kaufman; Beresini; Steven T. Laing; Wendy N. Sandoval; Maria N. Lorenzo; Jiansheng Wu; Justin Ly; Tom De Bruyn; Amy Heidersbach; Benjamin Haley; Alvin Gogineni; Robby M. Weimer; Dong Lee; Marie-Gabrielle Braun; Joachim Rudolph; Michael J. VanWyngarden; Daniel W. Sherbenou; Patricia Gomez-Bougie; Amiot; Diego Acosta-Alvear; Peter Walter; Avi Ashkenazi
View on Scopus
Synthesis of PI3K inhibitor GDC-0077 via a stereocontrolled N-arylation of α-amino acids
Tetrahedron, ISSN: 14645416 00404020
Chong Han; Sean M. Kelly; Theresa Cravillion; Scott Savage; Nguyen; Francis Gosselin
View on Scopus
Synthesis of PI3K inhibitor GDC-0077 via a stereocontrolled N-arylation of α-amino acids
Tetrahedron, ISSN: 14645416 00404020
Chong Han; Sean M. Kelly; Theresa Cravillion; Scott Savage; Tina Nguyen; Francis Gosselin
View on Scopus
Therapeutic Ligands Antagonize Estrogen Receptor Function by Impairing Its Mobility
Cell, ISSN: 10974172 00928674
Jane Guan; Wei Zhou; Marc Hafner; Robert A. Blake; Cecile Chalouni; Irene P. Chen; Tom De Bruyn; Jennifer M. Giltnane; Steven J. Hartman; Amy Heidersbach; Rene Houtman; Ellen Ingalla; Kategaya; Tracy L. Kleinheinz; Jun Li; Scott E. Martin; Zora Modrusan; Michelle Nannini; Jason Oeh; Savita Ubhayakar; Xiaojing Wang; Ingrid E. Wertz; Amy Young; Mamie Yu; Deepak Sampath; Jeffrey H. Hager; Lori S. Friedman; Anneleen Daemen; Ciara Metcalfe
View on Scopus
© 2024 Genentech, Inc. All rights reserved. This site is intended for US residents only.