Scientists / Publications

Publications

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DISPLAYING 3251 - 3300 OF 15191 RESULTS

Impact of Method of Preparation of Amorphous Solid Dispersions on Mechanical Properties: Comparison of Coprecipitation and Spray Drying
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Hao Helen Hou; Aniruddha Rajesh; Keyur Pandya; Joseph W. Lubach; Ariel Muliadi; Edward Yost; Wei Jia; Karthik Nagapudi
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Ribonucleoprotein Transfection for CRISPR/Cas9-Mediated Gene Knockout in Primary T Cells
Current Protocols in Immunology, ISSN: 1934368X 19343671
Soyoung A. Oh; Akiko Seki; Sascha Rutz
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Elevated IgE M1 prime transcripts in nasal tissues in patients with nasal polyps and asthma
Journal of Allergy and Clinical Immunology, ISSN: 10976825 00916749
Heleen Scheerens; Ashley Smith; Olga Li; Lee Honigberg; Harris; Gabriële Holtappels; Claus Bachert
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Atezolizumab in patients with advanced non-small cell lung cancer and history of asymptomatic, treated brain metastases: Exploratory analyses of the phase III OAK study
Lung Cancer, ISSN: 18728332 01695002
Shirish M. Gadgeel; Rimas V. Lukas; Jerome H Goldschmidt; Paul Conkling; Keunchil Park; Diego L Cortinovis; Filippo De Marinis; Achim Rittmeyer; Jyoti D. Patel; Joachim Von Pawel; Carol E. O'Hear; Catherine Lai; Hu; Ballinger; Alan Sandler; Mayank Gandhi; Louis Fehrenbacher
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A phase II, randomised study of mFOLFOX6 with or without the Akt inhibitor ipatasertib in patients with locally advanced or metastatic gastric or gastroesophageal junction cancer
European Journal of Cancer, ISSN: 18790852 09598049
Bang; Yoon-Koo Kang; Ng; Hyun Cheol Chung; Zev A. Wainberg; Steven Gendreau; Wai Y. Chan; Xu; Daniel Maslyar; Raymond D. Meng; Chau; Jaffer A. Ajani
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Multiethnic genome-wide association study of diabetic retinopathy using liability threshold modeling of duration of diabetes and glycemic control
Diabetes, ISSN: 1939327X 00121797
Samuela Pollack; Robert P. Igo; Richard A. Jensen; Mark Christiansen; Xiaohui Li; Ching-Yu Cheng; Maggie C. Y. Ng; Albert V Smith; Elizabeth Rossin; Ayellet V. Segrè; Samaneh Davoudi; Gavin S. Tan; Yii-Der Ida Chen; Jane Z. Kuo; Latchezar M. Dimitrov; Lynn K. Stanwyck; Weihua Meng; S. Mohsen Hosseini; Minako Imamura; Darryl Nousome; Jihye Kim; Yang Hai; Yucheng Jia; Jeeyun Ahn; Aaron Leong; Kaanan Shah; Kyu Hyung Park; Xiuqing Guo; Eli Ipp; Kent D. Taylor; Sharon G. Adler; John R. Sedor; Barry I. Freedman; I-Te Lee; Wayne H.-H. Sheu; Michiaki Kubo; Atsushi Takahashi; Samy Hadjadj; Michel Marre; David-Alexandre Trégouët; Roberta Mckean-Cowdin; Rohit Varma; Mark I. McCarthy; Leif Groop; Emma Ahlqvist; Valeriya Lyssenko; Elisabet Agardh; Andrew Morris; Alex S F Doney; Helen M. Colhoun; Iiro Toppila; Niina Sandholm; Per-Henrik Groop; Shiro Maeda; Craig L. Hanis; Alan Penman; Ching J. Chen; Heather Hancock; Paul Mitchell; Jamie E. Craig; Emily Y. Chew; Andrew D. Paterson; Michael A. Grassi; Colin Palmer; Donald W. Bowden; Brian L. Yaspan; David Siscovick; Mary Frances Cotch; Jie Jin Wang; Kathryn P. Burdon; Andrew K. Wong; Barbara E.K. Klein; Ronald Klein; Jerome I. Rotter; Sudha K. Iyengar; Alkes L. Price; Lucia Sobrin
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TomahaqCompanion: A Tool for the Creation and Analysis of Isobaric Label Based Multiplexed Targeted Assays
Journal of Proteome Research, ISSN: 15353907 15353893
Christopher M. Rose; Brian K. Erickson; Devin K. Schweppe; Rosa Viner; Jae Choi; John Rogers; Ryan Bomgarden; Steven P. Gygi; Donald S. Kirkpatrick
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Second-line and subsequent therapy and outcomes for follicular lymphoma in the United States: data from the observational National LymphoCare Study
British Journal of Haematology, ISSN: 13652141 00071048
Brian K. Link; Bann-Mo Day; Zhou; Zelenetz; Keith Dawson; James R. Cerhan; Christopher R. Flowers; Jonathan W. Friedberg
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Real-world use of bevacizumab in metastatic colorectal, metastatic breast, advanced ovarian and cervical cancer:A systematic literature review
Future Oncology, ISSN: 17448301 14796694
Sherif Raouf; Gianfilippo Bertelli; Agnes Ograbek; Polly Field; Irwin Tran
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Randomized phase II study evaluating AKT blockade with ipatasertib, in combination with abiraterone, in patients with metastatic prostate cancer with and without PTEN loss
Clinical Cancer Research, ISSN: 15573265 10780432
De Bono; Ugo De Giorgi; Daniel Nava Rodrigues; Christophe Massard; Sergio Bracarda; Albert Font; Jose Angel Arranz Arija; Kent Shih; George Daniel Radavoi; Xu; Wai Y. Chan; Han Ma; Steven Gendreau; Ruth Riisnaes; Premal Patel; Daniel Maslyar; Viorel Jinga
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TET2-dependent hydroxymethylome plasticity reduces melanoma initiation and progression
Cancer Research, ISSN: 15387445 00085472
Elise Bonvin; Enrico Radaelli; Martin Bizet; Flavie Luciani; Emilie Calonne; Pascale Putmans; David Nittner; Nitesh Kumar Singh; Sara F. Santagostino; Valerie Petit; Lionel Larue; Jean-Christophe Marine; François Fuks
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Fixed duration of venetoclax-rituximab in relapsed/refractory chronic lymphocytic leukemia eradicates minimal residual disease and prolongs survival: Post-treatment follow-up of the Murano phase III study
Journal of Clinical Oncology, ISSN: 15277755 0732183X
Kater; John F. Seymour; Hillmen; Barbara Eichhorst; Anton W. Langerak; Carolyn J. Owen; Maria Verdugo; Jenny Q. Wu; Elizabeth A. Punnoose; Yanwen Jiang; Jue Wang; Michelle Boyer; Kathryn Humphrey; Mehrdad Mobasher; Thomas J. Kipps
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Targeting IL-10 family cytokines for the treatment of human diseases
Cold Spring Harbor Perspectives in Biology, ISSN: 19430264
Xiaoting Wang; Kit Wong; Wenjun Ouyang; Sascha Rutz
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Phase I study of the anti-FcRH5 antibody-drug conjugate DFRF4539A in relapsed or refractory multiple myeloma
Blood Cancer Journal, ISSN: 20445385
A. Keith Stewart; Amrita Y. Krishnan; Seema Singhal; Ralph V. Boccia; Manish R. Patel; Ruben Niesvizky; Chanan-Khan; Sikander Ailawadhi; Jochen Brumm; Kirsten E. Mundt; Kyu Hong; Jacqueline McBride; Quyen Shon-Nguyen; Yuanyuan Xiao; Vanitha Ramakrishnan; Andrew G. Polson; Divya Samineni; Douglas Leipold; Eric W. Humke; James Scott McClellan; Jesus G. Berdeja
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MYOD1 functions as a clock amplifier as well as a critical co-factor for downstream circadian gene expression in muscle
eLife, ISSN: 2050084X
Brian A. Hodge; Xiping Zhang; Miguel A. Gutierrez-Monreal; Yi Cao; David W. Hammers; Zizhen Yao; Christopher A. Wolff; Ping Du; Denise Kemler; Andrew R. Judge; Karyn A. Esser
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Evaluation of polysaccharide-based chiral stationary phases in modern SFC-MS/MS for enantioselective bioanalysis
Bioanalysis, ISSN: 17576199 17576180
Liuxi Chen; Brian J. Dean; Xiaorong Liang
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Correlation of cytomegalovirus (CMV) disease severity and mortality with CMV viral burden in CMV-seropositive donor and CMV-seronegative solid organ transplant recipients
Open Forum Infectious Diseases, ISSN: 23288957
Jacqueline McBride; Daniel Sheinson; Jenny Jiang; Nicholas Lewin-Koh; Barbara G. Werner; Jennifer K.L. Chow; Xiaoning Wu; Jorge A. Tavel; David R. Snydman
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Comparative Effectiveness of Non-cisplatin First-line Therapies for Metastatic Urothelial Carcinoma: Phase 2 IMvigor210 Study Versus US Patients Treated in the Veterans Health Administration
European Urology Oncology, ISSN: 25889311
Nancy Vander Velde; Annie Guérin; Raluca Ionescu-Ittu; Sherry Shi; Eric Q. Wu; Shih Wen Lin; Ling-I Hsu; Kai-Uwe Saum; Sabine de Ducla; Jingjing Wang; Shi Li; AnnChristine Thåström; Shuqian Liu; Lizheng Shi; John T. Leppert
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Correction: Rheumatoid arthritis-interstitial lung disease in the United States: Prevalence, incidence, and healthcare costs and mortality (Journal of Rheumatology (2018))
Journal of Rheumatology, ISSN: 14992752 0315162X
Karina Raimundo; Joshua J. Solomon; Amy L. Olson; Amanda M. Kong; Ashley L. Cole; Aryeh Fischer; Jeffrey J. Swigris
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MANF regulates metabolic and immune homeostasis in ageing and protects against liver damage
Nature Metabolism, ISSN: 25225812
Pedro Sousa-Victor; Joana Neves; Wendy Cedron-Craft; P. Britten Ventura; Chen-Yu Liao; Rebeccah Riley; Ilya Soifer; Nicholas Van Bruggen; Ganesh Kolumam; Saul A. Villeda; Deepak A. Lamba; Heinrich Jasper
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Clinicopathologic Correlation of Aneurysmal Type 1 Neovascularization in Age-Related Macular Degeneration
Kidney International Reports, ISSN: 24686530
Miaoling Li; Rosa Dolz-Marco; Jeffrey D. Messinger; Kenneth R. Sloan; Daniela Ferrara; Christine A. Curcio; K. Bailey Freund
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Multiple-gene targeting and mismatch tolerance can confound analysis of genome-wide pooled CRISPR screens
Genome Biology, ISSN: 1474760X 14747596
Jean-Philippe Fortin; Jenille Tan; Karen Gascoigne; Peter M. Haverty; William F. Forrest; Michael Costa; Scott E. Martin
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Identification of Selective Acyl Sulfonamide-Cycloalkylether Inhibitors of the Voltage-Gated Sodium Channel (Na V ) 1.7 with Potent Analgesic Activity
Journal of Medicinal Chemistry, ISSN: 15204804 00222623
Shaoyi Sun; Qi Jia; Alla Zenova; Michael S. Wilson; Sultan Chowdhury; Thilo Focken; Jun Li; Shannon M. Decker; Michael Grimwood; Jean-Christophe Andrez; Ivan Hemeon; Tao Sheng; Chien-An Chen; Andrew D. White; David Hackos; Lunbin Deng; Girish Bankar; Kuldip Khakh; Elaine Chang; Rainbow Kwan; Sophia Lin; Karen Nelkenbrecher; Benjamin D. Sellers; Antonio G. DiPasquale; Jae H. Chang; Jodie Pang; Luis E. Sojo; Andrea Lindgren; Matthew Waldbrook; Zhiwei Xie; Clint Young; Johnson; C. Lee Robinette; Charles J. Cohen; Brian S. Safina; Daniel P. Sutherlin; Daniel F. Ortwine; Christoph Dehnhardt
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CCNE1 amplification is associated with poor prognosis in patients with triple negative breast cancer
BMC Cancer, ISSN: 14712407
Zi-Ming Zhao; Susan E. Yost; Katherine E. Hutchinson; Sierra Min Li; Yate-Ching Yuan; Javad Noorbakhsh; Zheng Liu; Charles Warden; Johnson; Xiwei Wu; Jeffrey H. Chuang; Yuan Yuan
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Process Development for a Locally Acting SGLT1 Inhibitor, LX2761, Utilizing sp 3 -sp 2 Suzuki Coupling of a Benzyl Carbonate
Organic Process Research and Development, ISSN: 1520586X 10836160
Lauren E. Sirois; Matthew M. Zhao; Ngiap-Kie Lim; Mark S. Bednarz; Bryce A. Harrison; Wenxue Wu
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Development, Optimization, and Structural Characterization of an Efficient Peptide-Based Photoaffinity Cross-Linking Reaction for Generation of Homogeneous Conjugates from Wild-Type Antibodies
Bioconjugate Chemistry, ISSN: 15204812 10431802
Nicholas Vance; Neelie Zacharias; Ultsch; Guangmin Li; Aimee Fourie; Peter S. Liu; Julien Lafrance-Vanasse; James A. Ernst; Wendy N. Sandoval; Katherine R. Kozak; Gail L. Phillips; Weiru Wang; Jack D. Sadowsky
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Directed Cp Rh III -Catalyzed Fluorosulfonylvinylation of Arenes
Organometallics, ISSN: 15206041 02767333
Gqwetha Ncube; Malcolm P. Huestis
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Study of a Competing Hydrodefluorination Reaction during the Directed ortho-Lithiation/Borylation of 2-Fluorobenzaldehyde
Organometallics, ISSN: 15206041 02767333
Frederic St-Jean; Katarzyna A. Piechowicz; Lauren E. Sirois; Remy Angelaud; Francis Gosselin
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Fatty acid recognition in the Frizzled receptor family
Journal of Biological Chemistry, ISSN: 1083351X 00219258
Aaron H Nile; Rami N. Hannoush
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Regio- and Enantioselective Iridium-Catalyzed Amination of Racemic Branched Alkyl-Substituted Allylic Acetates with Primary and Secondary Aromatic and Heteroaromatic Amines
Journal of the American Chemical Society, ISSN: 15205126 00027863
Seung Wook Kim; Leyah A. Schwartz; Jason R. Zbieg; Craig E. Stivala; Michael J. Krische
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Baseline characteristics associated with early visual acuity gains after ranibizumab treatment for retinal vein occlusion
BMC Ophthalmology, ISSN: 14712415
W. Lloyd Clark; Mimi Liu; John Kitchens; Pin-Wen Wang; Zdenka Haskova
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Why Computed Protein Folding Landscapes Are Sensitive to the Water Model
Journal of Chemical Theory and Computation, ISSN: 15499626 15499618
Ramu Anandakrishnan; Saeed Izadi; Alexey V. Onufriev
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In Vivo Stability Profiles of Anti-factor D Molecules Support Long-Acting Delivery Approaches
Molecular Pharmaceutics, ISSN: 15438392 15438384
Kelly M. Loyet; Hass; Wendy N. Sandoval; Ashley Morando; Peter S. Liu; Whitney Shatz; Leslie Dickmann; Margaret Kenrick; Jeremy Good; Teresa Davancaze; Alyssa M. Morimoto; Robert F. Kelley; Justin M. Scheer
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Trehalose Limits Fragment Antibody Aggregation and Influences Charge Variant Formation in Spray-Dried Formulations at Elevated Temperatures
Molecular Pharmaceutics, ISSN: 15438392 15438384
Karthikan Rajagopal; Debby P. Chang; Purnendu K. Nayak; Saeed Izadi; Thomas W. Patapoff; Jennifer Zhang; Robert F. Kelley; Alavattam Sreedhara
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In Situ Characterization of the Microstructural Evolution of Biopharmaceutical Solid-State Formulations with Implications for Protein Stability
Molecular Pharmaceutics, ISSN: 15438392 15438384
Stijn H.S. Koshari; Purnendu K. Nayak; Shalini Burra; Isidro E. Zarraga; Karthikan Rajagopal; Yun Liu; Norman J. Wagner; Abraham M. Lenhoff
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A phase I, randomized, observer-blinded, single and multiple ascending-dose study to investigate the safety, pharmacokinetics, and immunogenicity of BITS7201A, a bispecific antibody targeting IL-13 and IL-17, in healthy volunteers 11 Medical and Health Sciences 1102 Cardiorespiratory Medicine and Haematology
BMC Pulmonary Medicine, ISSN: 14712466
Tracy Staton; Kun Peng; Ryan Owen; David F. Choy; Christopher R. Cabanski; Alice Fong; Flavia Brunstein; Kathila R. Alatsis; Hubert Chen
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Seeking universal detectors for analytical characterizations
Journal of Pharmaceutical and Biomedical Analysis, ISSN: 1873264X 07317085
Kelly Zhang; Kenji L. Kurita; Venkatramani; David J. Russell
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Commensal-specific T cell plasticity promotes rapid tissue adaptation to injury
Science, ISSN: 10959203 00368075
Oliver J. Harrison; Jonathan L. Linehan; Han-Yu Shih; Nicolas Bouladoux; Seong-Ji Han; Margery Smelkinson; Shurjo K. Sen; Allyson L. Byrd; Michel Enamorado; Chen Yao; Samira Tamoutounour; Francois Van Laethem; Charlotte Hurabielle; Nicholas Collins; Andrea Paun; Rosalba Salcedo; John J. O'Shea; Yasmine Belkaid
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Macrolactamization Approaches to Arylomycin Antibiotics Core
Organic Letters, ISSN: 15237052 15237060
Ngiap-Kie Lim; Xin Linghu; Nicholas Wong; Haiming Zhang; C. Gregory Sowell; Francis Gosselin
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A telescoped Knochel-Hauser/Kumada-Corriu coupling strategy to functionalized aromatic heterocycles
Tetrahedron Letters, ISSN: 18733581 00404039
Kyle Clagg; Sara Hold; Archana Kumar; Stefan G. Koenig; Remy Angelaud
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Cellular Plasticity in Intestinal Homeostasis and Disease
Cell Stem Cell, ISSN: 18759777 19345909
Felipe de Sousa e Melo; Frederic J. De Sauvage
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High-resolution glycosylation site-engineering method identifies MICA epitope critical for shedding inhibition activity of anti-MICA antibodies
mAbs, ISSN: 19420870 19420862
T. Noelle Lombana; Marissa L. Matsumoto; Amy M. Berkley; Evangeline Toy; Ryan Cook; Yutian Gan; Du; Paul D. Schnier; Wendy N. Sandoval; Zhengmao Ye; Jill Schartner; Kim; Christoph Spiess
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Strategies for modifying drug residence time and ocular bioavailability to decrease treatment frequency for back of the eye diseases
Expert Opinion on Drug Delivery, ISSN: 17447593 17425247
Whitney Shatz; Jeffrey Aaronson; Stefan T. Yohe; Robert F. Kelley; Yogeshvar N. Kalia
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Rapid Identification of Disulfide Bonds and Cysteine-Related Variants in an IgG1 Knob-into-Hole Bispecific Antibody Enhanced by Machine Learning
Analytical Chemistry, ISSN: 15206882 00032700
Jordan Baker; Dana McDaniel; David Cain; Paula Lee Tao; Charlene Li; Yuting Huang; Hongbin Liu; Judith Zhu-Shimoni; Milady Ninonuevo
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Enabling adoption of 2D-NMR for the higher order structure assessment of monoclonal antibody therapeutics
mAbs, ISSN: 19420870 19420862
Robert G. Brinson; John P. Marino; Frank Delaglio; Luke W. Arbogast; Ryan M. Evans; Anthony Kearsley; Geneviève Gingras; Houman Ghasriani; Yves Aubin; Gregory K. Pierens; Xinying Jia; Mehdi Mobli; Hamish G. Grant; David W. Keizer; Kristian Schweimer; Jonas Ståhle; Göran Widmalm; Edward R. Zartler; Chad W. Lawrence; Patrick N. Reardon; John R. Cort; Ping Xu; Feng Ni; Saeko Yanaka; Koichi Kato; Stuart R. Parnham; Desiree Tsao; Andreas Blomgren; Torgny Rundlöf; Nils Trieloff; Peter Schmieder; Ross; Ken Skidmore; Kang Chen; David Keire; Darón I. Freedberg; Thea Suter-Stahel; Gerhard Wider; Gregor Ilc; Janez Plavec; Scott A. Bradley; Donna M. Baldisseri; Mauricio Luis Sforça; Ana Carolina de Mattos Zeri; Julie Yu Wei; Christina M. Szabo; Carlos A. Amezcua; John B. Jordan; Mats Wikström
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Quantitative Determination of Protein-Ligand Affinity by Size Exclusion Chromatography Directly Coupled to High-Resolution Native Mass Spectrometry
Analytical Chemistry, ISSN: 15206882 00032700
Chengfeng Ren; Aaron O. Bailey; Erica Vanderporten; Angela Oh; Wilson Phung; Melinda M. Mulvihill; Seth F. Harris; Yichin Liu; Guanghui Han; Wendy N. Sandoval
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Hematopoietic Progenitor Kinase-1 Structure in a Domain-Swapped Dimer
Structure, ISSN: 18784186 09692126
Ping Wu; Chris J. Sneeringer; Keith Pitts; Eric S. Day; Bryan K. Chan; Binqing Wei; Isabelle Lehoux; Kyle Mortara; Hong Li; Jiansheng Wu; Yvonne Franke; John Moffat; Jane L. Grogan; Timothy P. Heffron; Weiru Wang
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Borrowing From Historical Control Data in Cancer Drug Development: A Cautionary Tale and Practical Guidelines
Statistics in Biopharmaceutical Research, ISSN: 19466315
Connor Jo Lewis; Somnath Sarkar; Jiawen Zhu; Bradley P. Carlin
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Omalizumab Effectiveness by Biomarker Status in Patients with Asthma: Evidence From PROSPERO, A Prospective Real-World Study
Journal of Allergy and Clinical Immunology: In Practice, ISSN: 22132198
Thomas B. Casale; Allan T. Luskin; William W. Busse; Robert S. Zeiger; Benjamin L. Trzaskoma; Ming Yang; Noelle M. Griffin; Bradley E. Chipps
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Consistently very poorly controlled asthma is associated with greater activity and school impairment in children with severe or difficult-to-treat asthma
Journal of Allergy and Clinical Immunology: In Practice, ISSN: 22132198
Leonard B. Bacharier; Ronina A. Covar; Tmirah Haselkorn; Ahmar Iqbal; Cynthia Alvarez; David R. Mink; Hubert Chen; Robert S. Zeiger
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