Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 9751 - 9800 OF 16124 RESULTS

Effect of temperature, pH, dissolved oxygen, and hydrolysate on the formation of triple light chain antibodies in cell culture.
Biotechnology Progress, ISSN: 15206033
Natalia Gomez; Jun Ouyang; Mary D. H. Nguyen; Abigail R Vinson; Andy Lin; Inn H. Yuk
View on Scopus
Structure of the Complex between HER2 and an Antibody Paratope Formed by Side Chains from Tryptophan and Serine
Journal of Molecular Biology, ISSN: 00222836
Robert D. Fisher; Ultsch; Andreas Lingel; Gabriele Schaefer; Lily Shao; Sara Birtalan; Sachdev S. Sidhu; Eigenbrot
View on Scopus
Randomized, double-masked, sham-controlled trial of ranibizumab for neovascular age-related macular degeneration: PIER study year 2
American Journal of Ophthalmology, ISSN: 00029394
Prema Abraham; Huibin Yue; Laura J. Wilson
View on Scopus
On the possibility of self-induction of drug protein binding
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Leonid M. Berezhkovskiy
View on Scopus
Questions about coverage accompany new fully implantable hearing system
Managed Care, ISSN: 10623388
Thomas Morrow
View on Scopus
Molecular biomarker analyses using circulating tumor cells
PLoS ONE, ISSN: 19326203
Elizabeth A. Punnoose; Siminder Atwal; Jill M. Spoerke; Heidi Savage; Ajay Pandita; Ru-Fang Yeh; Andrea Pirzkall; Bernard M. Fine; Lukas Amler; Daniel S. Chen; Lackner
View on Scopus
Cell biology redux.
Molecular Biology of the Cell, ISSN: 19394586
Ira Mellman
View on Scopus
Molecular mechanisms of regulatory T cell development and suppressive function
Progress in Molecular Biology and Translational Science, ISSN: 18771173
Kim
View on Scopus
Surface expression of precursor N-cadherin promotes tumor cell invasion
Neoplasia (United States), ISSN: 14765586 15228002
Deborah Maret; Eugenia Gruzglin; Mohamad Seyed Sadr; Vincent Siu; Shan; Alexander W. Koch; Nabil G. Seidah; Rolando F. del Maestro; David R. Colman
View on Scopus
Standardizing rodent trimming and embedding guidelines for histology: Improving efficiency in the laboratory
Journal of Histotechnology, ISSN: 01478885
Monika Larson; Taylor; Marjie Van Hoy
View on Scopus
Factors affecting the viscosity in high concentration solutions of different monoclonal antibodies
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Sandeep Yadav; Steven J. Shire; Devendra S. Kalonia
View on Scopus
Semi-automated protein binding methodology using equilibrium dialysis and a novel mixed-matrix cassette approach
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Emile G. Plise; Daniel Tran; Laurent Salphati
View on Scopus
Pharmaceutical medical information contact centers: Results of three benchmarking surveys
Drug Information Journal, ISSN: 00928615
Pete Guillot; Stacey M. Fung
View on Scopus
Foreword
Separation Science and Technology, ISSN: 15205754 01496395
James M. van Alstine; Philip M. Lester
View on Scopus
Molecular predictors of 3D morphogenesis by breast cancer cell lines in 3D culture
PLoS Computational Biology, ISSN: 15537358 1553734X
Ju Han; Hang Chang; Orsi Giricz; Genee Y. Lee; Frederick L. Baehner; Joe W. Gray; Mina J. Bissell; Paraic A. Kenny; Bahram Parvin
View on Scopus
Robust preparation of novel imidazo[5,1-b][1,3,4]oxadiazoles
Organic and Biomolecular Chemistry, ISSN: 14770520
Tuan P. Tran; Nandini C. Patel; Brian Samas; Jacob B. Schwarz
View on Scopus
Interleukin (IL)-23 mediates Toxoplasma gondii-induced immunopathology in the gut via matrixmetalloproteinase-2 and IL-22 but independent of IL-17
Journal of Experimental Medicine, ISSN: 00221007 15409538
Melba Muñoz; Markus Heimesaat; Kerstin Danker; Daniela Struck; Uwe Lohmann; Rita Plickert; Stefan Bereswill; André Fischer; Ildikò Rita Dunay; Kerstin Wolk; Christoph Loddenkemper; Hans-Willi Krell; Claude Libert; Leif R. Lund; Oliver Frey; Christoph Hölscher; Yoichiro Iwakura; Nico Ghilardi; Wenjun Ouyang; Thomas Kamradt; Robert Sabat; Oliver Liesenfeld
View on Scopus
Interlaced size exclusion liquid chromatography of monoclonal antibodies
Journal of Chromatography A, ISSN: 00219673
Dell Farnan; G. Tony Moreno; Stults; Andreas Becker; Guillaume Tremintin; Mark van Gils
View on Scopus
Improving therapeutic efficacy of a complement receptor by structure-based affinity maturation
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Bing Li; Hongkang Xi; Laurie Diehl; Wyne P. Lee; Lizette Sturgeon; Jason Chinn; Laura DeForge; Robert F. Kelley; Wiesmann; Menno Van Lookeren Campagne; Sachdev S. Sidhu
View on Scopus
IL-23 is required for protection against systemic infection with Listeria monocytogenes
Journal of Immunology, ISSN: 00221767 15506606
Karen D. Meeks; Amy N. Sieve; Jay K. Kolls; Nico Ghilardi; Rance E. Berg
View on Scopus
Cutting edge: Depletion of Foxp3+ cells leads to induction of autoimmunity by specific ablation of regulatory T cells in genetically targeted mice
Journal of Immunology, ISSN: 00221767 15506606
Kim; Katharina Lahl; Shohei Hori; Christoph Loddenkemper; Ashutosh Chaudhry; Paul DeRoos; Alexander Y. Rudensky; Tim Sparwasser
View on Scopus
X chromosome-linked inhibitor of apoptosis regulates cell death induction by proapoptotic receptor agonists
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Eugene Varfolomeev; Bruno Alicke; J. Michael Elliott; Zobel; Kristina West; Harvey Wong; Justin M. Scheer; Avi Ashkenazi; Stephen Gould; Wayne J. Fairbrother; Domagoj Vucic
View on Scopus
Unraveling the Allosteric Mechanism of Serine Protease Inhibition by an Antibody
Structure, ISSN: 09692126
Rajkumar Ganesan; Eigenbrot; Yan Wu; Wei-Ching Liang; Steven Shia; Michael T. Lipari; Daniel Kirchhofer
View on Scopus
Human mammary cancer progression model recapitulates methylation events associated with breast premalignancy
Breast Cancer Research, ISSN: 14655411 1465542X
Nancy Dumont; Yongping Crawford; Mahvash Sigaroudinia; Shefali S. Nagrani; Matthew B. Wilson; Gertrude C. Buehring; Gulisa Turashvili; Samuel A. Aparicio; Mona L. Gauthier; Colleen A. Fordyce; Kimberly M. McDermott; Thea D. Tlsty
View on Scopus
Somatic Mutations in p85α Promote Tumorigenesis through Class IA PI3K Activation
Cancer Cell, ISSN: 15356108
Bijay S. Jaiswal; Vasantharajan Janakiraman; Noelyn Kljavin; Subhra Chaudhuri; Howard M. Stern; Weiru Wang; Zhengyan Kan; Hashem A. Dbouk; Brock A. Peters; Waring; Trisha Dela Vega; Denise M. Kenski; Krista K. Bowman; Maria N. Lorenzo; Hong Li; Jiansheng Wu; Zora Modrusan; Stinson; Mike Eby; Peng Yue; Joshua S. Kaminker; Frederic J. De Sauvage; Jonathan M. Backer; Somasekar Seshagiri
View on Scopus
Transport-metabolism interplay
Molecular Pharmaceutics, ISSN: 15438384 15438392
Laurent Salphati
View on Scopus
Identification, expression, and functional characterization of full-length and splice variants of murine organic anion transporting polypeptide 1b2
Molecular Pharmaceutics, ISSN: 15438384 15438392
Henriette E. Meyer Zu Schwabedissen; Joseph A. Ware; Rommel G. Tirona; Richard B. Kim
View on Scopus
Plasma membrane calcium ATPase 4 and the remodeling of calcium homeostasis in human colon cancer cells
Carcinogenesis, ISSN: 01433334 14602180
Cho S. Aung; Weilan Ye; Greg D. Plowman; Amelia A. Peters; Gregory R. Monteith; Sarah J. Roberts-Thomson
View on Scopus
Identifying genotype-dependent efficacy of single and combined PI3K- and MAPK-pathway inhibition in cancer
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424 10916490
Martin L. Sos; Stefanie Fischer; Roland Ullrich; Martin Peifer; Johannes M. Heuckmann; Mirjam Koker; Stefanie Heynck; Isabel Stückrath; Jonathan Weiss; Florian Fischer; Kathrin Michel; Aviva Goel; Lucia Regales; Katerina Politi; Samanthi Perera; Matthäus Getlik; Lukas C. Heukamp; Sascha Ansén; Thomas Zander; Rameen Beroukhim; Hamid Kashkar; Kevan Shokat; William R. Sellers; Daniel Rauh; Christine Orr; Klaus P. Hoeflich; Lori S. Friedman; Kwok-Kin Wong; William Pao; Roman K. Thomas
View on Scopus
Identification of codon-specific serine to asparagine mistranslation in recombinant monoclonal antibodies by high-resolution mass spectrometry
Analytical Chemistry, ISSN: 00032700
X. Christopher Yu; Oleg V. Borisov; Melissa Alvarez; David A. Michels; Yajun Jennifer Wang; Victor Ling
View on Scopus
Add-on omalizumab (xolair) for moderate-to-severe, allergic asthma in children
P and T, ISSN: 10521372
Henry Milgrom; Andrea Anderson
View on Scopus
Strategies for the cloning and expression of membrane proteins
Advances in Protein Chemistry and Structural Biology, ISSN: 18761623
Christopher M. Koth; Jian Payandeh
View on Scopus
NMR assignments of the human cytokine interleukin-33
Biomolecular NMR Assignments, ISSN: 18742718 1874270X
Andreas Lingel; Wayne J. Fairbrother
View on Scopus
The inflammasomes
PLoS Pathogens, ISSN: 15537366 15537374
Lamkanfi; Vishva M. Dixit
View on Scopus
Complement receptor of the Ig superfamily enhances complement-mediated phagocytosis in a subpopulation of tissue resident macrophages
Journal of Immunology, ISSN: 15506606 00221767
Nick N. Gorgani; Jeannie Q. He; Kenneth J. Katschke Jr.; Karim Y. Helmy; Hongkang Xi; Micah Steffek; Hass; Menno Van Lookeren Campagne
View on Scopus
New small-molecule inhibitor class targeting human immunodeficiency virus type 1 virion maturation
Antimicrobial Agents and Chemotherapy, ISSN: 00664804 10986596
Wade S. Blair; Joan Cao; Juin Fok-Seang; Paul Griffin; Jason Isaacson; R. Lynn Jackson; Edward Murray; Amy K. Patick; Qinghai Peng; Manos Perros; Chris Pickford; Hua Wu; Scott L. Butler
View on Scopus
A Robust, automated Karl Fischer titration system
Pharmaceutical Technology, ISSN: 15432521
Philippe Lam; Mike Nariman
View on Scopus
Characterization of oligosaccharides in recombinant tissue plasminogen activator produced in Chinese hamster ovary cells: Two decades of analytical technology development
Analytical Chemistry, ISSN: 00032700
Oleg V. Borisov; Field; Victor Ling; Reed J. Harris
View on Scopus
Biochemical analysis of the anaphase promoting complex: Activities of E2 enzymes and substrate competitive (pseudosubstrate) inhibitors
Methods in Molecular Biology, ISSN: 10643745
Matthew K. Summers; Peter K Jackson
View on Scopus
Responsiveness of NEI VFQ-25 to changes in visual acuity in neovascular AMD: Validation studies from two phase 3 clinical trials
Investigative Ophthalmology and Visual Science, ISSN: 01460404 15525783
Ivan J. Suñer; Gregg T. Kokame; Elaine B. Yu; James Ward; Chantal M. Dolan; Neil M. Bressler
View on Scopus
The ABRF edman sequencing research group 2008 study: Investigation into homopolymeric amino acid N-terminal sequence tags and their effects on automated edman degradation
Journal of Biomolecular Techniques, ISSN: 15240215 19434731
Thoma; Smith; Wendy N. Sandoval; Leone; Hunziker; Hampton; Linse; Denslow
View on Scopus
Tests and confidence intervals for secondary endpoints in sequential clinical trials
Biometrika, ISSN: 00063444 14643510
Tze Leung Lai; Mei-Chiung Shih; Zheng Su
View on Scopus
Correlation between aortic motion and vessel bulging in a murine aneurysm model using small animal magnetic resonance imaging
Proceedings of the ASME Summer Bioengineering Conference 2009, SBC2009,
Craig J. Goergen; Gilwoo Choi; Maj Hedehus; Charles A. Taylor; Philip S. Tsao; Joan M. Greve
View on Scopus
SGX523 is an exquisitely selective, ATP-competitive inhibitor of the MET receptor tyrosine kinase with antitumor activity in vivo
Molecular Cancer Therapeutics, ISSN: 15357163
Sean G. Buchanan; Jorg Hendle; Patrick S. Lee; Christopher R. Smith; Pierre-Yves Bounaud; Katti A. Jessen; Crystal M. Tang; Nanni H. Huser; Jeremy D. Felce; Karen J. Froning; Marshall C. Peterman; Brandon E. Aubol; Steve F. Gessert; J. Michael Sauder; Kenneth D. Schwinn; Marijane Russell; Isabelle A. Rooney; Jason Adams; Barbara C. Leon; Tuan H. Do; Jeff Blaney; Paul A. Sprengeler; Devon A. Thompson; Lydia Smyth; Laura A. Pelletier; Shane Atwell; Kevin Holme; Stephen R. Wasserman; Spencer Emtage; Stephen K. Burley; Siegfried H. Reich
View on Scopus
The chaperonin TRiC blocks a huntingtin sequence element that promotes the conformational switch to aggregation
Nature Structural and Molecular Biology, ISSN: 15459993 15459985
Stephen Tam; Christoph Spiess; William Auyeung; Lukasz Joachimiak; Bryan Chen; Michelle A. Poirier; Judith Frydman
View on Scopus
Macrophage metalloelastase: Stretching therapeutic opportunities
Journal of Molecular Cell Biology, ISSN: 16742788 17594685
Jeannie Q. He; Menno Van Lookeren Campagne
View on Scopus
Foreword
Recent Advances in Angiogenesis and Antiangiogenesis,
Napoleone Ferrara
View on Scopus
Generation of an OMgp allelic series in mice
Genesis, ISSN: 1526954X 1526968X
Jae K. Lee; Lauren C Case; Andrea F. Chan; Yuhong Zhu; Marc Tessier-Lavigne; Binhai Zheng
View on Scopus
Neogenin regulates skeletal myofiber size and focal adhesion kinase and extracellular signal-regulated kinase activities in vivo and in vitro
Molecular Biology of the Cell, ISSN: 10591524
Gyu-Un Bae; Youn-Joo Yang; Guoying Jiang; Mingi Hong; Hye-Jin Lee; Marc Tessier-Lavigne; Jong-Sun Kang; Robert S. Krauss
View on Scopus
Regulation of Class IA PI 3-kinases: C2 domain-iSH2 domain contacts inhibit p85/p110α and are disrupted in oncogenic p85 mutants
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424 10916490
Haiyan Wu; Chandra Shekar; Rory J. Flinn; Mirvat El-Sibai; Bijay S. Jaiswal; K. Ilker Sen; Vasantharajan Janakiraman; Somasekar Seshagiri; Gary J. Gerfen; Mark E. Girvin; Jonathan M. Backer
View on Scopus
© 2025 Genentech, Inc. All rights reserved. This site is intended for US residents only.