Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 10151 - 10200 OF 16124 RESULTS

A tumor sorting protocol that enables enrichment of pancreatic adenocarcinoma cells and facilitation of genetic analyses
Journal of Molecular Diagnostics, ISSN: 15251578
Zachary Boyd; Rajiv Raja; Stephanie Johnson; Eberhard; Lackner
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The fate of free radicals in a cellulose based hydrogel: Detection by electron paramagnetic resonance spectroscopy
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Lipika Basumallick; Junyan A. Ji; Nariman Naber; Y. John Wang
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Identification of circulating neuropilin-1 and dose-dependent elevation following anti-neuropilin-1 antibody administration
mAbs, ISSN: 19420862
Yanmei Lu; Hong Xiang; Peter S. Liu; Raymond K. Tong; Ryan J. Watts; Alexander W. Koch; Wendy N. Sandoval; Lisa A. Damico; Lee Wong Wai; Meng
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Assessing medical information needs via an internet-based survey
Drug Information Journal, ISSN: 00928615
Stacey M. Fung; Laura Merriman; Maureen Cawley
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Prasugrel, new platelet inhibitor, subject of formulary debates.
Managed Care, ISSN: 10623388
Thomas Morrow
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Root UV-B sensitive2 acts with root UV-B sensitive1 in a root ultraviolet B-sensing pathway
Plant Physiology, ISSN: 15322548 00320889
Colin D. Leasure; Hongyun Tong; Gigi Yuen; Xuewen Hou; Xuefeng Sun; Zheng-Hui He
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Baseline characteristics of patients enrolled in EXCELS: A cohort study
Annals of Allergy, Asthma and Immunology, ISSN: 15344436 10811206
Aidan Long; James E. Fish; Abdelkader Rahmaoui; Mary K. Miller; Mary S. Bradley; Hassan N. Taki; Anthony N. Demeo; Stephen A. Tilles; Stanley J. Szefler
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Viscoelastic characterization of high concentration antibody formulations using quartz crystal microbalance with dissipation monitoring
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Ankit Patel; Bruce A. Kerwin; Sekhar R. Kanapuram
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A stepwise increase in recombinant human growth hormone dosing during puberty achieves improved pubertal growth: A national cooperative growth study report
Journal of Pediatric Endocrinology and Metabolism, ISSN: 0334018X
Linda Riddick; Craig Alter; Daniel Aaron Davis; James W. Frane; Barbara M. Lippe; Bert Bakker
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Sensitivity of administrative claims to identify incident cases of lung cancer: A comparison of 3 health plans
Journal of Managed Care Pharmacy, ISSN: 10834087
Scott D. Ramsey; John F. Scoggins; David Blough; Cara L. McDermott; Carolina Reyes
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Transgenic goats are key to antithrombin production
Managed Care, ISSN: 10623388
Thomas Morrow
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Expanded availability of isotope boon to neuroblastoma diagnosis
Managed Care, ISSN: 10623388
Thomas Morrow
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Orphan disease gains second treatment option
Managed Care, ISSN: 10623388
Thomas Morrow
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Design and construction of synthetic phage-displayed Fab libraries.
Methods in Molecular Biology, ISSN: 10643745
Jenny Bostrom; Fuh
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Consistently very poorly controlled asthma, as defined by the impairment domain of the Expert Panel Report 3 guidelines, increases risk for future severe asthma exacerbations in The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study
Journal of Allergy and Clinical Immunology, ISSN: 00916749
Tmirah Haselkorn; James E. Fish; Robert S. Zeiger; Stanley J. Szefler; Dave P. Miller; Bradley E. Chipps; F. Estelle R. Simons; Weiss; Sally E. Wenzel; Larry Borish; Eugene R. Bleecker
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Prediction of the possibility of the secondary peaks of iv bolus drug plasma concentration time curve by the model that directly takes into account the transit time through the organ
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Leonid M. Berezhkovskiy
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Therapeutic potential of an anti-CD79b antibody-drug conjugate, anti-CD79b-vc-MMAE, for the treatment of non-Hodgkin lymphoma
Blood, ISSN: 15280020 00064971
David Dornan; Bennett; Chen; Dennis; Dan L. Eaton; Kristi Elkins; French; MaryAnn Go; Andrew S. Jack; Jagath R. Junutula; Koeppen; Jeffrey Lau; Jacqueline McBride; Andy Rawstron; Xiaoyan Shi; Nancy Yu; Shang-Fan Yu; Peng Yue; Bing Zheng; Allen Ebens; Andrew G. Polson
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Targeting the purinome.
Methods in Molecular Biology, ISSN: 19406029
Jeremy Murray; Dirksen Bussiere
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Development of a novel method for predicting human volume of distribution at steady-state of basic drugs and comparative assessment with existing methods
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Patrick Poulin; Frank-Peter Theil
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Viable tumor tissue detection in murine metastatic breast cancer by whole-body MRI and multispectral analysis
Magnetic Resonance in Medicine, ISSN: 15222594 07403194
Kai H. Barck; Brandon Willis; Ross; French; Ellen H. Filvaroff; Richard A. D. Carano
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Methionine, tryptophan, and histidine oxidation in a model protein, PTH: Mechanisms and stabilization
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Junyan A. Ji; Boyan Zhang; Wilson Cheng; Y. John Wang
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Second- and third-line treatment of patients with non-small-cell lung cancer with erlotinib in the community setting: Retrospective study of patient healthcare utilization and symptom burden
Clinical Lung Cancer, ISSN: 15257304
Edward J. Stepanski; Arthur C. Houts; Lee S. Schwartzberg; Mark S. Walker; Carolina Reyes; Johnetta Blakely
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The role of MITF phosphorylation sites during coat color and eye development in mice analyzed by bacterial artificial chromosome transgene rescue
Genetics, ISSN: 00166731 00166731
Georg L. Bauer; Christian Praetorius; Kristín Bergsteinsdóttir; Jón H. Hallsson; Bryndís K. Gísladóttir; Alexander Schepsky; Deborah A. Swing; T. Norene O'Sullivan; Heinz Arnheiter; Keren Bismuth; Julien Debbache; Colin Fletcher; Søren Warming; Neal G. Copeland; Nancy A. Jenkins; Eiríkur Steingrímsson
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The changing roles of medical communications professionals: Evolution of the core curriculum
Drug Information Journal, ISSN: 00928615
Alicia Alexander Cadogan; Stacey M. Fung
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Coordinated concentration changes of transcripts and metabolites in Saccharomyces cerevisiae
PLoS Computational Biology, ISSN: 15537358 1553734X
Patrick H. Bradley; Matthew J. Brauer; Joshua D. Rabinowitz; Olga G. Troyanskaya
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Axonal pathfinding: Guidance activities of sonic hedgehog (Shh)
Encyclopedia of Neuroscience,
Frédéric Charron; Marc Tessier-Lavigne
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Axonal Pathfinding: Netrins
Encyclopedia of Neuroscience,
Simon W. Moore; Timothy E. Kennedy; Marc Tessier-Lavigne
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Quantifying the usefulness of PD biomarkers in Phase 2 screening trials of oncology drugs
Statistics in Medicine, ISSN: 02776715 10970258
Holmgren
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Cells of adult brain germinal zone have properties akin to hair cells and can be used to replace inner ear sensory cells after damage
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424 10916490
Dongguang Wei; Snezana Levic; Liping Nie; Gao; Christine Petit; Edward G. Jones; Ebenezer N. Yamoah
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Quantitation of polysorbate 20 in protein solutions using mixed-mode chromatography and evaporative light scattering detection
Journal of Chromatography A, ISSN: 00219673
Daniel Hewitt; Taylor Zhang; Kao
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Mass spectrometric analysis of type 1 inositol 1,4,5-trisphosphate receptor ubiquitination
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Danielle A. Sliter; Kazuishi Kubota; Donald S. Kirkpatrick; Kamil J. Alzayady; Steven P. Gygi; Richard J. H. Wojcikiewicz
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Near infrared spectroscopic characterisation of secondary structure content of proteins
Journal of Near Infrared Spectroscopy, ISSN: 09670335
Leon N. Hsu; Tanya P. Lin; Samir Sane
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Recommendations for the validation of immunoassays used for detection of host antibodies against biotechnology products
Journal of Pharmaceutical and Biomedical Analysis, ISSN: 07317085
Gopi Shankar; Viswanath Devanarayan; Lakshmi Amaravadi; Yu Chen Barrett; Ronald Bowsher; Deborah Finco-Kent; Michele Fiscella; Boris Gorovits; Susan Kirschner; Michael Moxness; Thomas Parish; Quarmby; Holly W. Smith; Wendell Smith; Linda A. Zuckerman; Koren
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The Filamentous Actin Cross-Linking/Bundling Activity of Mammalian Formins
Journal of Molecular Biology, ISSN: 00222836
Osigwe Esue; Elizabeth S. Harris; Henry N. Higgs; Denis Wirtz
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Generation of a prostate from a single adult stem cell
Nature, ISSN: 00280836 14764679
Kevin G. Leong; Bu-Er Wang; Leisa Johnson; Gao
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A BBSome Subunit Links Ciliogenesis, Microtubule Stability, and Acetylation
Developmental Cell, ISSN: 15345807
Alexander V. Loktev; Qihong Zhang; John S. Beck; Charles C. Searby; Todd E. Scheetz; J.Fernando Bazan; Diane C. Slusarski; Val C. Sheffield; Peter K Jackson; Maxence V. Nachury
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Distinct Thresholds Govern Myc's Biological Output In Vivo
Cancer Cell, ISSN: 15356108
Daniel J. Murphy; Melissa Junttila; Laurent Pouyet; Anthony N. Karnezis; Ksenya Shchors; Duyen A. Bui; Lamorna Brown Swigart; Leisa Johnson; Gerard I. Evan
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The conjugate addition-Peterson olefination reaction for the preparation of cross-conjugated cyclopentenone, PPAR-γ ligands
Organic and Biomolecular Chemistry, ISSN: 14770520
Mazhar Iqbal; Patricia Duffy; Paul Evans; George Cloughley; Bernard B. Allan; Agustí Lledó; Xavier Verdaguer; Antoni Riera
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Validation of column-based chromatograhy processes for the purification of proteins
PDA Journal of Pharmaceutical Science and Technology, ISSN: 10797440
Brandeth; Chris Bussineau; Michelle D. Butler; Tony Christensen; Doris Conrad; Becky Devine; Ranga Godavarti; Eric Grund; Norbert Hentschel; Philip M. Lester; Jennifer McNay; Michael Muegge; Stephen Notarnicola; Rahul Patel; Laurie Scaggs
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Independent development of hydrolysate-containing and hydrolysate-free cho cell culture processes yields different optimal conditions
AIChE Annual Meeting, Conference Proceedings,
Diane M. Wuest; Polina Rapoport; Deborah E. Pascoe
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Chirality vs. HOMFLY and Kauffman polynomials
Journal of Knot Theory and its Ramifications, ISSN: 02182165
Sandy Ganzell; Amy V. Kapp
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Erratum: PCSK9 function and physiology (Journal of Lipid Research)
Journal of Lipid Research, ISSN: 00222275 15397262
Andrew S. Peterson; Loren G. Fong; Stephen G. Young
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Effects of cell culture conditions on antibody N-glycosylation- What causes high mannose 5 glycoform
AIChE Annual Meeting, Conference Proceedings,
Efren Pacis; Feng Li; Darren Brown; Robert Bayer
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Analysis of the nucleotide sequence of the guinea pig cytomegalovirus (GPCMV) genome
Virology Journal, ISSN: 1743422X
Mark R. Schleiss; Alistair McGregor; K Yeon Choi; Shailesh V. Date; Xiaohong Cui; Michael A. McVoy
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Startle reactivity in children at risk for migraine
Clinical Neurophysiology, ISSN: 13882457
Roman Duncko; Lihong Cui; Jeffrey Hille; Christian Grillon; Kathleen R. Merikangas
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Cooperation of the agonistic DR5 antibody apomab with chemotherapy to inhibit orthotopic lung tumor growth and improve survival
Clinical Cancer Research, ISSN: 10780432
Hongkui Jin; Renhui Yang; Ross; Fong; Richard A. D. Carano; Klara Totpal; David Lawrence; Zhong Zheng; Koeppen; Howard M. Stern; Ralph H. Schwall; Avi Ashkenazi
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Are health-care relationships important for mammography adherence in Latinas?
Journal of General Internal Medicine, ISSN: 08848734 15251497
Vanessa B. Sheppard; Judy Wang; Bin Yi; Toni Michelle Harrison; Shibao Feng; Elmer E. Huerta; Jeanne S. Mandelblatt
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Automated monitoring of mammalian cell cultures via an auto-sampler and an integrated multi-functional off-line analyzer
AIChE Annual Meeting, Conference Proceedings,
Gayle E. Derfus; Daniel Abramzon; Meg Tung; Robert Kiss; Ashraf Amanullah
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The p85α subunit of class IA phosphatidylinositol 3-kinase regulates the expression of multiple genes involved in osteoclast maturation and migration
Molecular and Cellular Biology, ISSN: 02707306
Veerendra Munugalavadla; Sasidhar Vemula; Emily Sims; Subha Krishnan; Shi Chen; Jincheng Yan; Huijie Li; Paul J. Niziolek; Clifford Takemoto; Alexander G. Robling; Feng-Chun Yang; Reuben Kapur
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High throughput ADME screening: Practical considerations, impact on the portfolio and enabler of in silico ADME models
Current Drug Metabolism, ISSN: 13892002
Cornelis E. Hop; Mark J. Cole; Ralph E. Davidson; David B. Duignan; James Federico; John S. Janiszewski; Kelly Jenkins; Suzanne Krueger; Rebecca Lebowitz; Theodore E. Liston; Walter Mitchell; Mark Snyder; Stefan J. Steyn; John R. Soglia; Christine Taylor; Troutman; John Umland; Michael West; Kevin M. Whalen; Veronica Zelesky; Sabrina X. Zhao
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