Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 10851 - 10900 OF 16124 RESULTS

ABRF-PRG04: Differentiation of protein isoforms
Journal of Biomolecular Techniques, ISSN: 19434731 15240215
David Arnott; Mary Ann Gawinowicz; Jeffrey A. Kowalak; William Lane; Kaye D. Speicher; Christoph W. Turck; Karen A. West; Thomas A. Neubert
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For patients with a broken hip, news of a lifetime replacement
Managed Care, ISSN: 10623388
Thomas Morrow
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Oncogenic regulators and substrates of the anaphase promoting complex/cyclosome are frequently overexpressed in malignant tumors
American Journal of Pathology, ISSN: 00029440
Norman L. Lehman; Rob Tibshirani; Jerry Y. Hsu; Yasodha Natkunam; Brent T. Harris; Robert B. West; Marilyn A. Masek; Kelli Montgomery; Matt Van De Rijn; Peter K Jackson
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Lym-1-induced apoptosis of non-Hodgkin's lymphomas produces regression of transplanted tumors
Cancer Biotherapy and Radiopharmaceuticals, ISSN: 10849785
Nan Zhang; Leslie A. Khawli; Peisheng Hu; Alan L. Epstein
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ADDRESS (ADministration of DRotrecogin alfa [activated] in Early stage Severe Sepsis) long-term follow-up: One-year safety and efficacy evaluation
Critical Care Medicine, ISSN: 00903493
Pierre-Francois Laterre; Edward Abraham; Jonathan M. Janes; Benjamin L. Trzaskoma; Nancy L. Correll; Frank V. Booth
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Fluid support worsens outcome and negates the benefit of protective antigen-directed monoclonal antibody in a lethal toxin-infused rat Bacillus anthracis shock model
Critical Care Medicine, ISSN: 00903493
Kevin Sherer; Yan Li; Xizhong Cui; Xuemei Li; Mani Subramanian; Mike Laird; Mahtab Moayeri; Stephen H. Leppla; Yvonne Fitz; Junwu Su; Peter Q. Eichacker
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Cox regression methods for two-stage randomization designs
Biometrics, ISSN: 15410420 0006341X
Yuliya Lokhnygina; Jeffrey D. Helterbrand
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Progressive Fibrosis in Nonalcoholic Steatohepatitis: Association With Altered Regeneration and a Ductular Reaction
Gastroenterology, ISSN: 00165085
Michelle M. Richardson; Julie R. Jonsson; Elizabeth E. Powell; Elizabeth M. Brunt; Brent A. Neuschwander-Tetri; Prithi S. Bhathal; John B. Dixon; Martin D. Weltman; Herbert Tilg; Alexander R. Moschen; David M. Purdie; Anthony J. Demetris; Andrew D. Clouston
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Lack of augmentation of tumor spectrum or severity in dual heterozygous Men1 and Rb1 knockout mice
Oncogene, ISSN: 14765594 09509232
Loffler; Biondi; Gartside; Serewko-Auret; Duncan; Tonks; Mould; Waring; Muller; Kay; Hayward
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Implications of pharmacogenomics in the current and future treatment of asthma
Journal of Managed Care Pharmacy, ISSN: 10834087
Thomas Morrow
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The effect of cosolutes on the isomerization of aspartic acid residues and conformational stability in a monoclonal antibody
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Aditya A. Wakankar; Jun Liu; David Vandervelde; Y. John Wang; Steven J. Shire; Ronald T. Borchardt
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Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion
Nature Cell Biology, ISSN: 14657392
Katarina Wolf; Yi I. Wu; Yueying Liu; Jörg Geiger; Eric Tam; Christopher Overall; M. Sharon Stack; Peter Friedl
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Risk Factors For Rate of Decline in Forced Expiratory Volume in One Second in Children and Adolescents with Cystic Fibrosis
Journal of Pediatrics, ISSN: 00223476
Michael W. Konstan; Morgan; Butler; David J. Pasta; Marcia L. Craib; Stefanie J. Silva; Dennis C. Stokes; Mary Ellen Wohl; Wagener; Warren E. Regelmann; Charles A. Johnson
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Gene expression microarray improves prediction of breast cancer outcomes
Managed Care, ISSN: 10623388
Thomas Morrow
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Angiographic and Optical Coherence Tomographic Results of the MARINA Study of Ranibizumab in Neovascular Age-Related Macular Degeneration
Ophthalmology, ISSN: 01616420
Peter K. Kaiser; Barbara A. Blodi; Howard Shapiro; Nisha R. Acharya
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A naturally occurring truncated β3 integrin in tumor cells: Native anti-integrin involved in tumor cell motility
Cancer Biology and Therapy, ISSN: 15558576 15384047
Rongxian Jin; Mohit Trikha; Yinlong Cai; David Grignon; Kenneth V. Honn
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A self-developed prechemotherapy education checklist.
Clinical journal of oncology nursing, ISSN: 10921095
Peggy S Mueller; Catherine A Glennon
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Cryoablation for atrial flutter requires no anesthesia
Managed Care, ISSN: 10623388
Thomas Morrow
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Should clinical complications affect USDA pain categories? C is correct.
Lab Animal, ISSN: 00937355
Gail T. Colbern; Lisa Heath
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Risk factors associated with persistent airflow limitation in severe or difficult-to-treat asthma: Insights from the TENOR study
Chest, ISSN: 00123692
June H. Lee; Tmirah Haselkorn; Larry Borish; Lawrence Rasouliyan; Bradley E. Chipps; Sally E. Wenzel
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On the determination of the time delay in reaching the steady state drug concentration in the organ compared to plasma
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Leonid M. Berezhkovskiy
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Human-derived clotting agent avoids immunogenicity
Managed Care, ISSN: 10623388
Thomas Morrow
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Ranibizumab for Predominantly Classic Neovascular Age-related Macular Degeneration: Subgroup Analysis of First-year ANCHOR Results
American Journal of Ophthalmology, ISSN: 00029394
Peter K. Kaiser; David M. Brown; Kang Zhang; Henry L. Hudson; Frank G. Holz; Howard Shapiro; Susan Schneider; Nisha R. Acharya
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The Hh signaling pathway in cancer.
Bulletin et mémoires de l'Académie royale de médecine de Belgique, ISSN: 03778231
Frederic J. De Sauvage
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A phase II, randomized, doubleblind, parallelgroup, placebocontrolled oral food challenge trial of Xolair (omalizumab) in peanut allergy
Journal of Allergy and Clinical Immunology, ISSN: 00916749
Hugh A. Sampson; Donald Y.M. Leung; A. Wesley Burks; Gideon Lack; Sami L. Bahna; Stacie M. Jones; Dennis A. Wong
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Cardiotrophin-1 defends the liver against ischemia-reperfusion injury and mediates the protective effect of ischemic preconditioning
Journal of Experimental Medicine, ISSN: 00221007 00221007
Maria Iñiguez; Carmen Berasain; Eduardo Martinez-Ansó; Matilde Bustos; Puri Fortes; Diane Pennica; Matias A. Avila; Jesús Prieto
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Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis
Nature, ISSN: 14764687 00280836
John B.B. Ridgway; Gu Zhang; Yan Wu; Scott Stawicki; Wei-Ching Liang; Yvan Chanthery; Joe Kowalski; Ryan J. Watts; Christopher Callahan; Ian Kasman; Mallika Singh; May Chien; Christine Tan; Hongo; Frederic J. De Sauvage; Greg D. Plowman; Minhong Yan
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Inhibition of carcinoma cell-derived VEGF reduces inflammatory characteristics in xenograft carcinoma
International Journal of Cancer, ISSN: 00207136 10970215
Alexei V. Salnikov; Nils-Erik Heldin; Linda B. Stuhr; Helge Wiig; Hans-Peter Gerber; Rolf K. Reed; Kristofer Rubin
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Making antibodies in bacteria
Making and Using Antibodies: A Practical Handbook,
Frederic A. Fellouse; Sachdev S. Sidhu
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An exclusion mechanism in ion exchange chromatography
Biotechnology and Bioengineering, ISSN: 00063592 10970290
Chithkala Harinarayan; Jay Mueller; Anders Ljunglöf; Fahrner; James M. Van Alstine; Van Reis
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TENOR risk score predicts healthcare in adults with severe or difficult-to-treat asthma
European Respiratory Journal, ISSN: 09031936
Mary K. Miller; June H. Lee; Paul D. Blanc; David J. Pasta; Gujrathi; Hal V. Barron; Sally E. Wenzel; Weiss
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Bringing science to cancer therapy
Yale Journal of Biology and Medicine, ISSN: 00440086
Ira Mellman
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Development and validation of a preference weight multiattribute health outcome measure for rheumatoid arthritis
Journal of Rheumatology, ISSN: 0315162X
Chiun-Fang Chiou; Maria E. Suarez-Almazor; Cathy D. Sherbourne; Chih-Hung Chang; Carolina Reyes; Michelle Dylan; Joshua Ofman; Daniel J. Wallace; Wesley Mizutani; Michael Weisman
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Sensitive detection of KIT D816V in patients with mastocytosis
Clinical Chemistry, ISSN: 00099147
Tan; David Westerman; McArthur; Kevin Lynch; Waring; Dobrovic
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Targeting the Hedgehog pathway in cancer
Nature Reviews Drug Discovery, ISSN: 14741776 14741784
Lee L. Rubin; Frederic J. De Sauvage
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High prevalence of skin test positivity in severe or difficult-to-treat asthma
Journal of Asthma, ISSN: 02770903 15324303
Tmirah Haselkorn; Larry Borish; Dave P. Miller; Weiss; Dennis A. Wong
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Elevated serum levels of interferon-regulated chemokines are biomarkers for active human systemic lupus erythematosus
PLoS Medicine, ISSN: 15491277 15491676
Jason W. Bauer; Emily C. Baechler; Michelle Petri; Franak Batliwalla; Dianna Crawford; Ward Ortmann; Karl J. Espe; Wentian Li; Dhavalkumar D. Patel; Peter K. Gregersen; Timothy W. Behrens
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Herpes zoster vaccine brings relief for the elderly.
Managed Care, ISSN: 10623388
Thomas Morrow
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Making independence work: Monitoring the bevacizumab colorectal cancer clinical trial
Data Monitoring in Clinical Trials: A Case Studies Approach,
Janet Wittes; Holmgren; Heidi Christ-Schmidt; Alex Bajamonde
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Estimation of baculovirus titer based on viable cell size
Nature Protocols, ISSN: 17542189 17502799
Vasantharajan Janakiraman; William F. Forrest; Somasekar Seshagiri
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Enhanced half-life of genetically engineered human IgG1 antibodies in a humanized FcRn mouse model: Potential application in humorally mediated autoimmune disease
International Immunology, ISSN: 09538178 14602377
Stefka B. Petkova; Shreeram Akilesh; Thomas J. Sproule; Gregory J. Christianson; Hana Al Khabbaz; Aaron C. Brown; Presta; Meng; Derry C. Roopenian
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Glucuronidation in the chimpanzee (Pan troglodytes): Studies with acetaminophen, oestradiol and morphine
Xenobiotica, ISSN: 00498254 13665928
Harvey Wong; James E. Grace Jr.; Matthew Wright; Browning; Grossman; Bai; David D. Christ
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Genetics of autoimmune diseases - Disorders of immune homeostasis
Nature Reviews Genetics, ISSN: 14710056 14710064
Peter K. Gregersen; Timothy W. Behrens
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Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling
Molecular and Cellular Proteomics, ISSN: 15359476
Pierre-Olivier Angrand; Inmaculada Segura; Pamela Völkel; Sonja Ghidelli; Rebecca Terry; Miro Brajenovic; Kristina Vintersten; Rüdiger Klein; Giulio Superti-Furga; Gerard Drewes; Bernhard Kuster; Tewis Bouwmeester; Amparo Acker-Palmer
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Sustained benefit in rheumatoid arthritis following one course of rituximab: Improvements in physical function over 2 years
Rheumatology, ISSN: 14620324 14620332
Vibeke Strand; Balbir-Gurman; Karel Pavelka; Paul Emery; Nicole F. Li; Ming Yin; Lehane; Sunil Agarwal
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Concluding summary: Proceedings of the AAPS Biotec Open Forum on "Aggregation of Protein Therapeutics"
AAPS Journal, ISSN: 15507416
Steven J. Shire; Cromwell; Jun Liu
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Protein NMR Spectroscopy: Principles and Practice
Protein NMR Spectroscopy: Principles and Practice,
John Cavanagh; Wayne J. Fairbrother; Arthur G. Palmer III; Mark Rance; Nicholas J. Skelton
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Selectivity improvements in highly charged UF membranes
Desalination, ISSN: 00119164
Alex Xenopoulos; Charkoudian; Robert Van Reis
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Boc is a receptor for sonic hedgehog in the guidance of commissural axons
Nature, ISSN: 14764687 00280836
Ami Okada; Frédéric Charron; Steves Morin; David S. Shin; Karen G. Wong; Pierre J. Fabre; Marc Tessier-Lavigne; Susan K. McConnell
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Rab14 is critical for maintenance of Mycobacterium tuberculosis phagosome maturation arrest
EMBO Journal, ISSN: 02614189 14602075
George B. Kyei; Isabelle Vergne; Jennifer Chua; Esteban Roberts; James Harris; Jagath R. Junutula; Vojo Deretic
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