Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 12651 - 12700 OF 15758 RESULTS

A novel soluble tissue factor variant with an altered factor VIIa binding interface
Journal of Biological Chemistry, ISSN: 00219258
Geoffrey F. Lee; Robert F. Kelley
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Mapping the charged residues in the second immunoglobulin-like domain of the vascular endothelial growth factor/placenta growth factor receptor Flt-1 required for binding and structural stability
Journal of Biological Chemistry, ISSN: 00219258
Terri Davis-Smyth; Presta; Napoleone Ferrara
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Pervasive conformational fluctuations on microsecond time scales in a fibronectin type III domain
Nature Structural Biology, ISSN: 10728368
Mikael Akke; Jun Liu; John Cavanagh; Harold P. Erickson; Arthur G. Palmer III
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Solution structure of the fourth metal-binding domain from the Menkes copper-transporting ATPase
Nature Structural Biology, ISSN: 10728368
Jane Gitschier; Moffat; Dorothea Reilly; William I. Wood; Wayne J. Fairbrother
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Potentiated angiogenic effect of scatter factor/hepatocyte growth factor via induction of vascular endothelial growth factor: The case for paracrine amplification of angiogenesis
Circulation, ISSN: 00097322
Eric Van Belle; Bernhard Witzenbichler; Donghui Chen; Marcy Silver; Ling Chang; Ralph H. Schwall; Jeffrey M. Isner
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Randomized trial of an oral platelet glycoprotein IIb/IIIa antagonist, sibrafiban, in patients after an acute coronary syndrome: Results of the TIMI 12 trial
Circulation, ISSN: 00097322
Christopher P. Cannon; Carolyn H. McCabe; Steven Borzak; Timothy D. Henry; Marc D. Tischler; Hiltrud S. Mueller; Robert Feldman; Sebastian T. Palmeri; Kenneth A. Ault; Scott A. Hamilton; Joel M. Rothman; Novotny; Eugene Braunwald
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Randomized trial of an oral platelet glycoprotein IIb/IIIa antagonist, sibrafiban, in patients after an acute coronary syndrome: Results of the TIMI 12 trial
Circulation, ISSN: 00097322
Christopher P. Cannon; Carolyn H. McCabe; Steven Borzak; Timothy D. Henry; Marc D. Tischler; Hiltrud S. Mueller; Robert Feldman; Sebastian T. Palmeri; Kenneth A. Ault; Scott Hamilton; Joel M. Rothman; Novotny; Eugene Braunwald
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Synergistic effects of Schwann- and muscle-derived factors on motoneuron survival involve GDNF and cardiotrophin-1 (CT-1)
Journal of Neuroscience, ISSN: 02706474
Vilma Arce; Richard A. Pollock; Jean-Marc Philippe; Diane Pennica; Christopher E. Henderson; Odile Delapeyrière
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Cytokines promote the survival of mouse cranial sensory neurones at different developmental stages
European Journal of Neuroscience, ISSN: 0953816X
Antony Horton; Perry F. Bartlett; Diane Pennica; Alun M. Davies
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An oligopeptide transporter is expressed at high levels in the pancreatic carcinoma cell lines AsPc-1 and Capan-2
Cancer Research, ISSN: 00085472
Deborah E. Gonzalez; Kuang-Ming Y. Covitz; Wolfgang Sadée; Mrsny
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Effect of smaller droplet size of dornase alfa on lung function in mild cystic fibrosis
Pediatric Pulmonology, ISSN: 87556863
David E. Geller; Howard Eigen; Stanley B. Fiel; Clark; André P. Lamarre; Charles A. Johnson; Michael W. Konstan
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Disruption of a putative SH3 domain and the proline-rich motifs in the 53-kDa substrate of the insulin receptor kinase does not alter its subcellular localization or ability to serve as a substrate
Journal of Cellular Biochemistry, ISSN: 07302312
Tammie C. Yeh; Wenlu Li; Gilbert-Andre Keller; Richard A. Roth
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An induced proximity model for caspase-8 activation
Journal of Biological Chemistry, ISSN: 00219258
Marta Muzio; Brent R. Stockwell; Henning R. Stennicke; Guy S. Salvesen; Vishva M. Dixit
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Probing the structural basis of the catalytic activity of HIV-1 PR through total chemical protein synthesis
Journal of Molecular Structure: THEOCHEM, ISSN: 01661280
Maria Miller; Baca; J.K. Mohana Rao; Stephen B. H. Kent
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Calcium-dependent Ret activation by GDNF and neurturin
Oncogene, ISSN: 09509232
Chika Nozaki; Naoya Asai; Hideki Murakami; Toshihide Iwashita; Yosuke Iwata; Keizo Horibe; Robert D. Klein; Rosenthal; Masahide Takahashi
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Adenovector-mediated expression of human thrombopoietin cDNA in immune- compromised mice: Insights into the pathophysiology of osteomyelofibrosis
Journal of Immunology, ISSN: 00221767
Beat M. Frey; Shahin Rafii; Michael Teterson; Dan L. Eaton; Crystal; Malcolm A.S. Moore
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Identification of a novel polyproline recognition site in the cytoskeletal associated protein, proline serine threonine phosphatase interacting protein
Journal of Biological Chemistry, ISSN: 00219258
Dowbenko; Spencer; Quan; Lasky
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Photoaffinity labeling by 4-thiodideoxyuridine triphosphate of the HIV- 1 reverse transcriptase active site during synthesis. Sequence of the unique labeled hexapeptide
Journal of Biological Chemistry, ISSN: 00219258
Shanhua Lin; William J. Henzel; Sunil Nayak; Don Dennis
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Identification of an inhibin receptor in gonadal tumors from inhibin α- subunit knockout mice
Journal of Biological Chemistry, ISSN: 00219258
Lawrence B. Draper; Matzuk; Veronica J. Roberts; Edward T. Cox; Jeffrey Weiss; Mather; Woodruff
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Role of vascular endothelial growth factor in ovarian cancer: Inhibition of ascites formation by immunoneutralization
American Journal of Pathology, ISSN: 00029440
Sam Mesiano; Napoleone Ferrara; Robert B. Jaffe
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The influence of manganese deficiency on serum IGF-1 and IGF binding proteins in the male rat
Proceedings of the Society for Experimental Biology and Medicine, ISSN: 00379727
Michael S. Clegg; Sharon M. Donovan; Marcia H. Monaco; Deborah L. Baly; Jodi L. Ensunsa; Carl L. Keen
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Phenylephrine, endothelin, prostaglandin F(2α), and leukemia inhibitory factor induce different cardiac hypertrophy phenotypes in vitro
Endocrine, ISSN: 15590100 1355008X
King; Jane Winer; David M. Phillips; James Quach; P. Mickey Williams; Mather
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Hepatocyte growth factor induces hepatocyte proliferation in vivo and allows for efficient retroviral-mediated gene transfer in mice
Hepatology, ISSN: 02709139
Gijsbert A. Patijn; Andre Lieber; David B. Schowalter; Ralph H. Schwall; Kay
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Statistical issues in assay development and use
Advances in Experimental Medicine and Biology, ISSN: 00652598
Giltinan
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GATA-dependent expression of the interleukin-1 receptor-related T1 gene in mast cells
Molecular and Cellular Biology, ISSN: 02707306
Thomas Gächter; Dirk R. Moritz; Jacqueline Gheyselinck; Roman Klemenz
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Recombinant human nerve growth factor in the treatments of diabetic polyneuropathy
Neurology, ISSN: 00283878
Apfel; Kessler; Bruce T. Adornato; Litchy; Corsee Sanders; Cynthia A. Rask
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Magnetic resonance imaging assessment of cerebral hemodynamics during spreading depression in rats
Journal of Cerebral Blood Flow and Metabolism, ISSN: 0271678X
De Crespigny; Joachim Röther; Nicholas Van Bruggen; Christian Beaulieu; Michael Moseley
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Aggregation of recombinant human interferon gamma: Kinetics and structural transitions
Journal of Pharmaceutical Sciences, ISSN: 00223549
Brent Kendrick; Cleland; Lam; Tue H. Nguyen; Theodore W. Randolph; Mark C. Manning; John F. Carpenter
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Regulation of hippocampal synaptic plasticity by the tyrosine kinase receptor, REK7/EphA5, and its ligand, AL-1/Ephrin-A5
Molecular and Cellular Neuroscience, ISSN: 10447431
Gao; Natasha Shinsky; Armanini; Paul Moran; Zheng; José-Luis Mendoza-Ramírez; Phillips; Winslow; Caras
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Antibody engineering
Current Opinion in Structural Biology, ISSN: 0959440X
William Dall'Acqua; Paul J. Carter
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Effect of long-term recombinant growth hormone therapy in children - The National Cooperative Growth Study, USA, 1985-1994
Journal of Pediatric Endocrinology and Metabolism, ISSN: 0334018X
Allen W. Root; Stephen F. Kemp; Amy Chen Rundle; Ken Dana; Kenneth M. Attie
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Lacrimal gland growth factors and receptors: Lacrimal fibroblastic cells are a source of tear HGF
Advances in Experimental Medicine and Biology, ISSN: 00652598
Wilson; Li; Mohan; Tervo; Vesaluoma; Bennett; Ralph H. Schwall; Tabor; Kim; Hargrave; Cuevas
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Mouth and oropharyngeal deposition of pharmaceutical aerosols
Journal of Aerosol Medicine: Deposition, Clearance, and Effects in the Lung, ISSN: 08942684
Clark; Newman; Nancy Dasovich
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Investigation on fouling mechanisms for recombinant human growth hormone sterile filtration
Journal of Pharmaceutical Sciences, ISSN: 00223549
Maa; Chung C. Hsu
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GFRα1 is an essential receptor component for GDNF in the developing nervous system and kidney
Neuron, ISSN: 08966273
Cacalano; Isabel Fariñas; Li-Chong Wang; Kelly E. Hagler; Alison Forgie; Mark Moore; Armanini; Phillips; Anne Ryan; Louis F. Reichardt; Mary Hynes; Alun M. Davies; Rosenthal
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Disturbances of growth hormone-insulin-like growth factor axis and response to growth hormone in acidosis
American Journal of Physiology - Regulatory Integrative and Comparative Physiology, ISSN: 03636119
Karina Jandziszak; Carlos Suarez; Ethan Wasserman; Ross Clark; Bonnie Baker; Frances Liu; Hintz; Saenger; Luc P. Brion
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Expression analysis of the soluble and membrane-associated forms of the interleukin-1 receptor-related T1 protein in primary mast cells and fibroblasts
Hybridoma, ISSN: 0272457X
Dirk R. Moritz; Jacqueline Gheyselinck; Roman Klemenz
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A method of biased coin randomization, its implementation, and its validation
Drug Information Journal, ISSN: 00928615
James W. Frane
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X-linked chronic granulomatous disease: Mutations in the CYBB gene encoding the gp91-phox component of respiratory-burst oxidase
American Journal of Human Genetics, ISSN: 00029297
Julie Rae; Peter E. Newburger; Mary C. Dinauer; Noack; Penelope J. Hopkins; Ryoko Kuruto; John T. Curnutte
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P-glycoprotein (P-gp) mediated efflux in Caco-2 cell monolayers: The influence of culturing conditions and drug exposure on P-gp expression levels
Journal of Pharmaceutical Sciences, ISSN: 00223549
Pascale Anderle; Eva Niederer; Rubas; Constanze Hilgendorf; Hilde Spahn-Langguth; Heidi Wunderli-Allenspach; Hans P. Merkle; Peter Langguth
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Regulation of megakaryocytopoiesis and platelet production: Lessons from animal models
Journal of Laboratory and Clinical Medicine, ISSN: 00222143
Frederic J. De Sauvage; Jean-Luc Villeval; Ramesh A. Shivdasani
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Acetogenesis does not replace ketogenesis in fasting piglets infused with hexanoate
American Journal of Physiology - Endocrinology and Metabolism, ISSN: 01931849
Adams; Jack Odle
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Treatment of idiopathic bronchiectasis with aerosolized recombinant human DNase I
Chest, ISSN: 00123692
Anne E. O'Donnell; Alan F. Barker; Jonathan S. Ilowite; Robert B. Fick Jr.
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Magnetic resonance imaging detects suppression of tumor vascular permeability after administration of antibody to vascular endothelial growth factor
Cancer Investigation, ISSN: 07357907
Christine D. Pham; Timothy P.L. Roberts; Nicholas Van Bruggen; Ostap Melnyk; Jeffry Mann; Napoleone Ferrara; Robert L. Cohen; Robert C. Brasch
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E. coli-based in vitro transcription/translation: In vivo-specific synthesis rates and high yields in a batch system
BioTechniques, ISSN: 07366205
Ranjan Patnaik; James R. Swartz
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Effect of excipients on the stability and structure of lyophilized recombinant human growth hormone
Journal of Pharmaceutical Sciences, ISSN: 00223549
Henry R. Costantino; Karen G. Carrasquillo; Rocio A. Cordero; Mumenthaler; Chung C. Hsu; Kai Griebenow
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Mutational analysis of human DNase I at the DNA binding interface: Implications for DNA recognition, catalysis, and metal ion dependence
Protein Science, ISSN: 09618368
Clark Q. Pan; Jana S. Ulmer; Herzka; Lazarus
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Recent antibody targeting technologies - A survey of the patent literature
Journal of Drug Targeting, ISSN: 1061186X
Mrsny
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For success, focus your strengths.
Nature Biotechnology, ISSN: 10870156
Levinson
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Hinge bending within the cytokine receptor superfamily revealed by the 2.4 Å crystal structure of the extracellular domain of rabbit tissue factor
Protein Science, ISSN: 09618368
Yves A. Muller; Robert F. Kelley; De Vos
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