Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 12901 - 12950 OF 16603 RESULTS

January 1, 2000

Effects of administration of a single dose of a humanized monoclonal antibody to CD11a on the immunobiology and clinical activity of psoriasis

Journal of the American Academy of Dermatology, ISSN: 01909622

Alice Gottlieb; James G. Krueger; Ross Bright; Mark Ling; Mark Lebwohl; Sewon Kang; Steve Feldman; Mary Spellman; Knut Wittkowski; Hans D. Ochs; Paula Jardieu; Bauer; Mark White; Russell L Dedrick; Marvin Garovoy

January 1, 2000

Induction of an angiogenic phenotype in endometriotic stromal cell cultures by interleukin-1β

Molecular Human Reproduction, ISSN: 13609947

Dan I. Lebovic; Frauke Bentzien; Victor A. Chao; Evelyn N. Garrett; Meng; Robert N. Taylor

January 1, 2000

Validation of excised bovine nasal mucosa as in vitro model to study drug transport and metabolic pathways in nasal epithelium

Journal of Pharmaceutical Sciences, ISSN: 00223549

M. Christiane Schmidt; Daniel Simmen; Monika Hilbe; Peter Boderke; Günter Ditzinger; Jürgen Sandow; Steffen Lang; Rubas; Hans P. Merkle

January 1, 2000

Fast probabilistic analysis of sequence function using scoring matrices

Bioinformatics, ISSN: 13674803

Thomas D Wu; Craig G. Nevill-Manning; Douglas L. Brutlag

January 1, 2000

Mammalian-cell-produced neurturin (NTN) is more potent than purified Escherichia coli-produced NTN

Experimental Neurology, ISSN: 00144886

Michael R. Hoane; Kamal D. Puri; Lei Xu; Paul F. Stabila; Hongmei Zhao; Amit G. Gulwadi; Phillips; Devaux; Mark D. Lindner; Weng Tao

January 1, 2000

Estimation in a Cox proportional hazards cure model

Biometrics, ISSN: 0006341X

Sy; Jeremy M.G. Taylor

January 1, 2000

Identification and regulation of receptor tyrosine kinases Rse and Mer and their ligand Gas6 in testicular somatic cells

Journal of Andrology, ISSN: 01963635

Michael C. W. Chan; Mather; Glynis McCray; Will M. Lee

January 1, 2000

Use of phage display for the generation of human antibodies that neutralize factor IXa function

Blood Coagulation and Fibrinolysis, ISSN: 09575235

Shelley Suggett; Daniel Kirchhofer; Hass; Michael T. Lipari; Paul Moran; Nagel; Judice; Kurt A. Schroeder; Jeffrey Tom; Henry B. Lowman; Adams; Dan L. Eaton; Devaux

January 1, 2000

Substrate-assisted catalysis: Molecular basis and biological significance

Protein Science, ISSN: 09618368

William Dall'Acqua; Paul J. Carter

January 1, 2000

Web Alert. Apoptosis.

Chemistry and Biology, ISSN: 10745521

Eric W. Humke

January 1, 2000

WECHE: A novel hematopoietic regulatory factor

Immunity, ISSN: 10747613

Osamu Ohneda; Kinuko Ohneda; Hisayuki Nomiyama; Zhong Zheng; Steven A. Gold; Fumio Arai; Takeshi Miyamoto; Bruce E. Taillon; Richard A. McIndoe; Richard A. Shimkets; Lewin; Toshio Suda; Lasky

January 1, 2000

Targeting genes and proteins in the analysis of learning and memory: Caveats and future directions

Reviews in the Neurosciences, ISSN: 03341763

Gerlai

January 1, 2000

Putting the pieces together: contribution of fluorescence polarization assays to small molecule lead optimization

Proceedings of SPIE - The International Society for Optical Engineering, ISSN: 0277786X

Keating; James C. Marsters Jr.; Beresini; Ladner; Kimberly Zioncheck; Clark; Arellano; Bodary

January 1, 2000

The 2.0 Å structure of bovine interferon-γ; assessment of the structural differences between species

Acta Crystallographica Section D: Biological Crystallography, ISSN: 09074449

Michael Randal; Anthony A. Kossiakoff

January 1, 2000

The glial cell line-derived neurotrophic factor family receptor components are differentially regulated within sensory neurons after nerve injury

Journal of Neuroscience, ISSN: 02706474

David L. H. Bennett; Timothy J. Boucher; Armanini; Kris Poulsen; Gregory J. Michael; John V. Priestley; Phillips; McMahon; David L. Shelton

January 1, 2000

The importance of growth hormone replacement therapy for bone mass in young adults with growth hormone deficiency

Journal of Pediatric Endocrinology and Metabolism, ISSN: 0334018X

Kenneth M. Attie

January 1, 2000

A reversed-phase HPLC assay for plasminogen activators

Journal of Liquid Chromatography and Related Technologies, ISSN: 10826076

Yuan Xu; Cacia

January 1, 2000

APO2L/TRAIL expression in human brain tumors

Acta Neuropathologica, ISSN: 00016322

Mitsutoshi Nakamura; Johannes Rieger; Michael Weller; Jin Kim; Paul Kleihues; Hiroko Ohgaki

January 1, 2000

Growth hormone safety update from the National Cooperative Growth Study

Journal of Pediatric Endocrinology and Metabolism, ISSN: 0334018X

Thomas J. Maneatis; Joyce Baptista; Connelly; Sandra L. Blethen

January 1, 2000

Role of the distal half of the c-Mpl intracellular domain in control of platelet production by thrombopoietin in vivo

Molecular and Cellular Biology, ISSN: 02707306

Shiuh-Ming Luoh; Stefanich; Gregg Solar; Hope Steinmetz; Michael T. Lipari; Tamara I. Pestina; Carl W. Jackson; Frederic J. De Sauvage

January 1, 2000

Concomitant over-expression of vascular endothelial growth factor and its receptors in pancreatic cancer

International Journal of Cancer, ISSN: 00207136

Jun Itakura; Toshiyuki Ishiwata; Shen; Marko Kornmann; Murray Korc

January 1, 2000

Analysis of PTCH/SMO/SHH pathway genes in medulloblastoma

Genes Chromosomes and Cancer, ISSN: 10452257

Russell H. Zurawel; Cory Allen; Sharon Chiappa; Walter Cato; Jaclyn Biegel; Philip Cogen; Frederic J. De Sauvage; Corey Raffel

January 1, 2000

Angiography of fluoresceinated anti-vascular endothelial growth factor antibody and dextrans in experimental choroidal neovascularization

Archives of Ophthalmology, ISSN: 00039950

Michael J. Tolentino; Deeba Husain; Panagiotis Theodosiadis; Evangelos S. Gragoudas; Edward Connolly; Jeanne Kahn; Cleland; Anthony P. Adamis; R. Andrew Cuthbertson; Joan W. Miller

January 1, 2000

The seven-transmembrane receptor Smoothened cell-autonomously induces multiple ventral cell types

Nature Neuroscience, ISSN: 10976256

Mary Hynes; Weilan Ye; Kevin Wang; Donna Stone; Maximilien Murone; Frederic J. De Sauvage; Rosenthal

January 1, 2000

The nucleoskeleton: Go EAST, young man

Nature Cell Biology, ISSN: 14657392

Lasky

January 1, 2000

Clonidine for smoking cessation.

Cochrane database of systematic reviews (Online : Update Software), ISSN: 1469493X

Steven G. Gourlay; Stead; Neal L. Benowitz

January 1, 2000

Gene expression profiling in an in vitro model of angiogenesis

American Journal of Pathology, ISSN: 00029440

Jeanne Kahn; Fuad Mehraban; Gladys S. Ingle; Xiaohua Xin; Juliet E. Bryant; Gordon A. Vehar; Schoenfeld; Grimaldi; Franklin V. Peale Jr.; Aparna Draksharapu; Lewin; Mary E. Gerritsen

January 1, 2000

Toll-like receptor 2-mediated NF-κB activation requires a Rac I-dependent pathway

Nature Immunology, ISSN: 15292908

Laurence Arbibe; Jean-Paul Mira; Nicole Teusch; Lois Kline; Mausumee Guha; Nigel Mackman; Godowski; Richard J. Ulevitch; Ulla G. Knaus

January 1, 2000

Pharmacokinetics and pharmacodynamics of tenecteplase: Results from a phase II study in patients with acute myocardial infarction

Journal of Clinical Pharmacology, ISSN: 00912700

Modi; Fox; Fong-Wong Clow; Tanswell; Christopher P. Cannon; Frans Van De Werf; Eugene Braunwald

January 1, 2000

Mice lacking α-synuclein display functional deficits in the nigrostriatal dopamine system

Neuron, ISSN: 08966273

Asa Abeliovich; Yvonne Schmitz; Isabel Fariñas; Choi-Lundberg; Ho; Pablo E. Castillo; Natasha Shinsky; Jose Manuel Garcia-Verdugo; Armanini; Anne Ryan; Mary Hynes; Phillips; David Sulzer; Rosenthal

January 1, 2000

Purification of yeast mitochondrial Hsp60.

Methods in Molecular Biology, ISSN: 10643745

Yves Dubaquié; Renate Looser; Sabine Rospert

January 1, 2000

Drug information in industry versus academia: A pharmacy resident's perspective of a sample case

Therapeutic Innovation and Regulatory Science, ISSN: 21684790

Graham; David A. Graves; Barry Grobman; Gary M. Mccart; Candy Tsourounis

January 1, 2000

Comparison of the rates of deamidation, diketopiperazine formation, and oxidation in recombinant human vascular endothelial growth factor and model peptides

AAPS PharmSci, ISSN: 15221059

Chimanlall Goolcharran; Andrew J.S. Jones; Ronald T. Borchardt; Cleland; Rodney Keck

January 1, 2000

Phage display in pharmaceutical biotechnology

Current Opinion in Biotechnology, ISSN: 09581669

Sachdev S. Sidhu

January 1, 2000

Pharmaceutical biotechnology the genomes are just the beginning: Editorial overview

Current Opinion in Biotechnology, ISSN: 09581669

Lawn; Lasky

January 1, 2000

Identification of paracaspases and metacaspases: Two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma

Molecular Cell, ISSN: 10972765

Anthony G. Uren; Karen M. O'Rourke; Aravind; Pisabarro; Somasekar Seshagiri; Eugene V. Koonin; Vishva M. Dixit

January 1, 2000

VEGF: An update on biological and therapeutic aspects

Current Opinion in Biotechnology, ISSN: 09581669

Napoleone Ferrara

January 1, 2000

Characterization of huJAM: Evidence for involvement in cell-cell contact and tight junction regulation

American Journal of Physiology - Cell Physiology, ISSN: 03636143

Tony W. Liang; Richard A. Demarco; Mrsny; Austin L. Gurney; Gray; Jeff Hooley; Holly L. Aaron; Arthur Huang; Toni Klassen; Daniel B. Tumas; Sherman Fong

January 1, 2000

Embryonic stem cells go dopaminergic

Neuron, ISSN: 08966273

Mary Hynes; Rosenthal

January 1, 2000

Pharmacokinetics and pharmacodynamics of sibrafiban, an orally administered GP IIb/IIIa antagonist, following coadministration of aspirin and heparin

Journal of Clinical Pharmacology, ISSN: 00912700

Reimann; Modi; Novotny

January 1, 2000

T-wave alternans and serious ventricular arrhythmias: A tale of two T-waves

Journal of the American College of Cardiology, ISSN: 07351097

Hal V. Barron

January 1, 2000

Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5

Immunity, ISSN: 10747613

Frank C. Kischkel; David Lawrence; Anan Chuntharapai; Peter Schow; K.Jin Kim; Avi Ashkenazi

January 1, 2000

Cardiotrophin-1 reduces stress-induced heat shock protein production in cardiac myocytes

Cytokine, ISSN: 10434666

Julia Railson; Kevin Lawrence; Anastatis Stephanou; Bhawanjit K. Brar; Diane Pennica; David S. Latchman

January 1, 2000

A neutralizing monoclonal antibody specific for the dimer interface region of IL-8

Cytokine, ISSN: 10434666

Laura DeForge; Henry B. Lowman; Leong; Anan Chuntharapai; Jin Kim; Hébert

January 1, 2000

Amino acid analysis, using postcolumn ninhydrin detection, in a biotechnology laboratory.

Methods in Molecular Biology, ISSN: 10643745

Frank D. Macchi; Felicity J. Shen; Rodney Keck; Reed J. Harris

January 1, 2000

Nonparametric estimation of a periodic function

Biometrika, ISSN: 00063444

Peter Hall; Reimann; John Rice

January 1, 2000

Characterization of Novel Neutralizing Monoclonal Antibodies Specific to Human Neurturin

Hybridoma, ISSN: 0272457X

Jo-Anne S. Kongo; Siao Ping Tsai; Moffat; Kurt A. Schroeder; Chris Jung; Anan Chuntharapai; Patricia A. Lampe; Eugene M. Johnson Jr.; Frederic J. De Sauvage; Armanini; Phillips; Devaux

January 1, 2000

Cytoskeletal protein PSTPIP1 directs the PEST-type protein tyrosine phosphatase to the c-Abl kinase to mediate Abl dephosphorylation

Molecular Cell, ISSN: 10972765

Feng Cong; Spencer; Jean-François Côté; Yan Wu; Michel L. Tremblay; Lasky; Stephen P. Goff

January 1, 2000

Structure and expression of a membrane component of the inhibin receptor system

Endocrinology, ISSN: 00137227

Huira Chong; Stephanie A. Pangas; Daniel J. Bernard; Eileen Wang; Jolee Gitch; Wei Chen; Lawrence B. Draper; Edward T. Cox; Woodruff

January 1, 2000

Epitope location on tissue factor determines the anticoagulant potency of monoclonal anti-tissue factor antibodies

Thrombosis and Haemostasis, ISSN: 03406245

Daniel Kirchhofer; Paul Moran; Nancy Y. Chiang; Kim; Markus A. Riederer; Eigenbrot; Robert F. Kelley

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