Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 13001 - 13050 OF 16125 RESULTS

Validation of a capillary isoelectric focusing method for the recombinant monoclonal antibody C2B8
Journal of Chromatography A, ISSN: 00219673
Glenn Hunt; Hotaling; Chen
View on Scopus
Elevated expression of KDR receptor in response to Vascular Endothelial Growth Factor (VEGF) treatment
FASEB Journal, ISSN: 08926638
Shen; David Y. Lee; Hans-Peter Gerber; Napoleone Ferrara; Keyt; Zioncheck
View on Scopus
CARP expression in two rat cardiac hypertrophy models
FASEB Journal, ISSN: 08926638
Michael Lew; Lesley A. Brown; Sehl; Kenneth J. Hillan; David G Lowe
View on Scopus
Immunoliposomes containing antibodies to costimulatory molecules as adjuvants for HIV subunit vaccines
AIDS Research and Human Retroviruses, ISSN: 08892229
Bulent Ozpolat; Xiao-Mei Rao; Powell; Lawrence B. Lachman
View on Scopus
The disruption of heregulin, ErbB2, and ErbB3 genes leads to cardiac and neural abnormalities: Roles in development and adulthood
FASEB Journal, ISSN: 08926638
Sharon Erickson
View on Scopus
Overexpression of Escherichia coli oxidoreductases increases recombinant insulin-like growth factor-I accumulation
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
John C. Joly; Leung; James R. Swartz
View on Scopus
Computational learning reveals coiled coil-like motifs in histidine kinase linker domains
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Mona Singh; Bonnie Berger; Peter S. Kim; James M. Berger; Andrea G Cochran
View on Scopus
Tyrosine phosphorylation regulates the SH3-mediated binding of the Wiskott-Aldrich syndrome protein to PSTPIP, a cytoskeletal-associated protein
Journal of Biological Chemistry, ISSN: 00219258
Yan Wu; Spencer; Lasky
View on Scopus
High resolution mapping of the binding site of TrkA for nerve growth factor and TrkC for neurotrophin-3 on the second immunoglobulin-like domain of the TrK receptors
Journal of Biological Chemistry, ISSN: 00219258
Urfer; Tsoulfas; O'Connell; Hongo; Wei Zhao; Presta
View on Scopus
Caspase-9, Bcl-X(L), and Apaf-1 form a ternary complex
Journal of Biological Chemistry, ISSN: 00219258
Pan; Karen M. O'Rourke; Vishva M. Dixit
View on Scopus
Ammonium ion and glucosamine dependent increases of oligosaccharide complexity in recombinant glycoproteins secreted from cultivated BHK-21 cells
Biotechnology and Bioengineering, ISSN: 00063592
Martin Gawlitzek; Ulrich Valley; Roland Wagner
View on Scopus
Establishment of conditionally immortalized rat utricular epithelial cell lines using a retrovirus-mediated gene transfer technique
Hearing Research, ISSN: 03785955
Zheng; Lewis; Gao
View on Scopus
Prebeta-1 HDL in plasma of normolipidemic individuals: Influences of plasma lipoproteins, age, and gender
Journal of Lipid Research, ISSN: 00222275
Patricia M. O'Connor; Zysow; Schoenhaus; Ishida; Kunitake; Naya-Vigne; Duchateau; Redberg; Susan J. Spencer; Mark; Mazur; Heilbron; Jaffe; Malloy; Kane
View on Scopus
Pharmacokinetics and pharmacodynamics of recombinant tissue-type plasminogen activator following intravenous administration in rabbits: A comparison of three dosing regimens
Biopharmaceutics and Drug Disposition, ISSN: 01422782
Stephen M. Eppler; Tauri D. Senn; Ellen Gilkerson; Modi
View on Scopus
The orphan receptor CRF2-4 is an essential subunit of the interleukin 10 receptor
Journal of Experimental Medicine, ISSN: 00221007
Spencer; Francesco Di Marco; Jeff Hooley; Sharon Pitts-Meek; Michele Bauer; Anne Ryan; Bernard Sordat; Gibbs; Michel Aguet
View on Scopus
Structure-function study of the extracellular domain of the human IFN- α receptor (hIFNAR1) using blocking monoclonal antibodies: The role of domains 1 and 2
Journal of Immunology, ISSN: 00221767
Lu; Anan Chuntharapai; Joanne T. Beck; Bass; Ow; De Vos; Gibbs; K.Jin Kim
View on Scopus
Structure-function study of the extracellular domain of the human IFN- α receptor (hIFNAR1) using blocking monoclonal antibodies: The role of domains 1 and 2
Journal of Immunology, ISSN: 00221767
Lu; Anan Chuntharapai; Joanne Beck; Bass; Ow; De Vos; Gibbs; K.Jin Kim
View on Scopus
A novel soluble tissue factor variant with an altered factor VIIa binding interface
Journal of Biological Chemistry, ISSN: 00219258
Geoffrey F. Lee; Robert F. Kelley
View on Scopus
Mapping the charged residues in the second immunoglobulin-like domain of the vascular endothelial growth factor/placenta growth factor receptor Flt-1 required for binding and structural stability
Journal of Biological Chemistry, ISSN: 00219258
Terri Davis-Smyth; Presta; Napoleone Ferrara
View on Scopus
Solution structure of the fourth metal-binding domain from the Menkes copper-transporting ATPase
Nature Structural Biology, ISSN: 10728368
Jane Gitschier; Moffat; Dorothea Reilly; William I. Wood; Wayne J. Fairbrother
View on Scopus
Pervasive conformational fluctuations on microsecond time scales in a fibronectin type III domain
Nature Structural Biology, ISSN: 10728368
Mikael Akke; Jun Liu; John Cavanagh; Harold P. Erickson; Arthur G. Palmer III
View on Scopus
Randomized trial of an oral platelet glycoprotein IIb/IIIa antagonist, sibrafiban, in patients after an acute coronary syndrome: Results of the TIMI 12 trial
Circulation, ISSN: 00097322
Christopher P. Cannon; Carolyn H. McCabe; Steven Borzak; Timothy D. Henry; Marc D. Tischler; Hiltrud S. Mueller; Robert Feldman; Sebastian T. Palmeri; Kenneth A. Ault; Scott Hamilton; Joel M. Rothman; Novotny; Eugene Braunwald
View on Scopus
Randomized trial of an oral platelet glycoprotein IIb/IIIa antagonist, sibrafiban, in patients after an acute coronary syndrome: Results of the TIMI 12 trial
Circulation, ISSN: 00097322
Christopher P. Cannon; Carolyn H. McCabe; Steven Borzak; Timothy D. Henry; Marc D. Tischler; Hiltrud S. Mueller; Robert Feldman; Sebastian T. Palmeri; Kenneth A. Ault; Scott A. Hamilton; Joel M. Rothman; Novotny; Eugene Braunwald
View on Scopus
Potentiated angiogenic effect of scatter factor/hepatocyte growth factor via induction of vascular endothelial growth factor: The case for paracrine amplification of angiogenesis
Circulation, ISSN: 00097322
Eric Van Belle; Bernhard Witzenbichler; Donghui Chen; Marcy Silver; Ling Chang; Ralph H. Schwall; Jeffrey M. Isner
View on Scopus
Disruption of a putative SH3 domain and the proline-rich motifs in the 53-kDa substrate of the insulin receptor kinase does not alter its subcellular localization or ability to serve as a substrate
Journal of Cellular Biochemistry, ISSN: 07302312
Tammie C. Yeh; Wenlu Li; Gilbert-Andre Keller; Richard A. Roth
View on Scopus
Effect of smaller droplet size of dornase alfa on lung function in mild cystic fibrosis
Pediatric Pulmonology, ISSN: 87556863
David E. Geller; Howard Eigen; Stanley B. Fiel; Clark; André P. Lamarre; Charles A. Johnson; Michael W. Konstan
View on Scopus
An oligopeptide transporter is expressed at high levels in the pancreatic carcinoma cell lines AsPc-1 and Capan-2
Cancer Research, ISSN: 00085472
Deborah E. Gonzalez; Kuang-Ming Y. Covitz; Wolfgang Sadée; Mrsny
View on Scopus
Cytokines promote the survival of mouse cranial sensory neurones at different developmental stages
European Journal of Neuroscience, ISSN: 0953816X
Antony Horton; Perry F. Bartlett; Diane Pennica; Alun M. Davies
View on Scopus
Synergistic effects of Schwann- and muscle-derived factors on motoneuron survival involve GDNF and cardiotrophin-1 (CT-1)
Journal of Neuroscience, ISSN: 02706474
Vilma Arce; Richard A. Pollock; Jean-Marc Philippe; Diane Pennica; Christopher E. Henderson; Odile Delapeyrière
View on Scopus
An induced proximity model for caspase-8 activation
Journal of Biological Chemistry, ISSN: 00219258
Marta Muzio; Brent R. Stockwell; Henning R. Stennicke; Guy S. Salvesen; Vishva M. Dixit
View on Scopus
Probing the structural basis of the catalytic activity of HIV-1 PR through total chemical protein synthesis
Journal of Molecular Structure: THEOCHEM, ISSN: 01661280
Maria Miller; Baca; J.K. Mohana Rao; Stephen B. H. Kent
View on Scopus
Calcium-dependent Ret activation by GDNF and neurturin
Oncogene, ISSN: 09509232
Chika Nozaki; Naoya Asai; Hideki Murakami; Toshihide Iwashita; Yosuke Iwata; Keizo Horibe; Robert D. Klein; Rosenthal; Masahide Takahashi
View on Scopus
Adenovector-mediated expression of human thrombopoietin cDNA in immune- compromised mice: Insights into the pathophysiology of osteomyelofibrosis
Journal of Immunology, ISSN: 00221767
Beat M. Frey; Shahin Rafii; Michael Teterson; Dan L. Eaton; Crystal; Malcolm A.S. Moore
View on Scopus
Photoaffinity labeling by 4-thiodideoxyuridine triphosphate of the HIV- 1 reverse transcriptase active site during synthesis. Sequence of the unique labeled hexapeptide
Journal of Biological Chemistry, ISSN: 00219258
Shanhua Lin; William J. Henzel; Sunil Nayak; Don Dennis
View on Scopus
Identification of a novel polyproline recognition site in the cytoskeletal associated protein, proline serine threonine phosphatase interacting protein
Journal of Biological Chemistry, ISSN: 00219258
Dowbenko; Spencer; Quan; Lasky
View on Scopus
Identification of an inhibin receptor in gonadal tumors from inhibin α- subunit knockout mice
Journal of Biological Chemistry, ISSN: 00219258
Lawrence B. Draper; Matzuk; Veronica J. Roberts; Edward T. Cox; Jeffrey Weiss; Mather; Woodruff
View on Scopus
Development and validation of the migraine-specific quality of life questionnaire
Headache, ISSN: 00178748
Priti Jhingran; Jane T. Osterhaus; David W. Miller; Jeffrey T. Lee; Leonard Kirchdoerfer
View on Scopus
A role for FADD in T cell activation and development
Immunity, ISSN: 10747613
Craig M. Walsh; Ben G. Wen; Arul M. Chinnaiyan; Karen M. O'Rourke; Vishva M. Dixit; Stephen M. Hedrick
View on Scopus
Increased physical activity and the growth hormone-IGF-I axis in adolescent males
American Journal of Physiology - Regulatory Integrative and Comparative Physiology, ISSN: 03636119
Alon Eliakim; Jo Anne Brasel; Subburaman Mohan; Wai Lee T. Wong; Dan M. Cooper
View on Scopus
Genetic approaches to the detection of contaminants in Escherichia coli fermentations
Biotechnology Progress, ISSN: 87567938
James R. Swartz; Nancy McFarland
View on Scopus
A data model for clinical study status reports
Drug Information Journal, ISSN: 00928615
David H. Christiansen; Sundin
View on Scopus
Local delivery of vascular endothelial growth factor via PLGA depots for treatment of vascular disease
Proceedings of the Controlled Release Society, ISSN: 10220178
Ann Park; Duenas; Thomas W. Patapoff; Cleland
View on Scopus
Pharmacokinetics, pharmacodynamics and tolerability of a potent, non-peptidic, GP IIb/IIIa receptor antagonist following multiple oral administrations of a prodrug form
Thrombosis and Haemostasis, ISSN: 03406245
Refino; Modi; Sherron L. Bullens; Cheryl Pater; Michael T. Lipari; Kirk D. Robarge; Brent Blackburn; Beresini; Thomas Weller; Beat Steiner; Bunting
View on Scopus
Development of stable formulations for PLGA/PLA microsphere vaccines
Research in Immunology, ISSN: 09232494
Cleland
View on Scopus
Requirement for Brn-3c in maturation and survival, but not in fate determination of inner ear hair cells
Development (Cambridge), ISSN: 09501991
Mengqing Xiang; Gao; Tama Hasson; Joyce J. Shin
View on Scopus
Stabilization of nerve growth factor during microencapsulation and release from microspheres
Proceedings of the Controlled Release Society, ISSN: 10220178
Lam; Duenas; Cleland
View on Scopus
Chromatography in biotechnology: A user's perspective
LC-GC Europe, ISSN: 14716577
John Frenz
View on Scopus
Integrins α(v)β3 and α5β1 mediate attachment of lyme disease spirochetes to human cells
Infection and Immunity, ISSN: 00199567
Jenifer Coburn; Loranne Magoun; Bodary; John M. Leong
View on Scopus
Calcium-phosphate mediated DNA transfer into HEK-293 cells in suspension: Control of physicochemical parameters allows transfection in stirred media: Transfection and protein expression in mammalian cells
Cytotechnology, ISSN: 09209069
Martin Jordan; Christiane Köhne; Florian M. Wurm
View on Scopus
Nab1, a corepressor of NGFI-A (Egr-1), contains an active transcriptional repression domain
Molecular and Cellular Biology, ISSN: 02707306
Alex H. Swirnoff; Elizabeth D. Apel; John Svaren; Bradley R. Sevetson; Drazen B. Zimonjic; Nicholas C. Popescu; Jeffrey Milbrandt
View on Scopus
© 2025 Genentech, Inc. All rights reserved. This site is intended for US residents only.