Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 13201 - 13250 OF 15666 RESULTS

The quaking gene product necessary in embryogenesis and myelination combines features of RNA binding and signal transduction proteins
Nature Genetics, ISSN: 10614036
Tom A. Ebersole; Qi Chen; Monica J. Justice; Karen Artzt
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Transforming growth factor β1 induces angiogenesis in vivo with a threshold pattern
Laboratory Investigation, ISSN: 00236837
Luis F. Fajardo; Stavros D. Prionas; Helen H. Kwan; Joe Kowalski; Anthony C. Allison
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Reproductive toxicity testing of therapeutic biotechnology agents
Teratology, ISSN: 00403709
Judith W. Henck; Kim G. Hilbish; Mercedes A. Serabian; Joy A. Cavagnaro; Andrew G. Hendrickx; Narsingh D. Agnish; Ada H.C. Kung; Joyce Mordenti
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Critical amino acids in the lymphocyte function-associated antigen-1 I domain mediate intercellular adhesion molecule 3 binding and immune function
Journal of Experimental Medicine, ISSN: 00221007
Yvette Van Kooyk; Minke E. Binnerts; Caroline P. Edwards; Mark Champe; Berman; Carl G. Figdor; Bodary
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Expression and regulation of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in distinct avian motoneuron subsets
Journal of Neurobiology, ISSN: 00223034
Nitza Kahane; David L. Shelton; Chaya Kalcheim
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Systematic improvement of a chemically-defined protein-free medium for hybridoma growth and monoclonal antibody production
Journal of Biotechnology, ISSN: 01681656
Stoll; Mühlethaler; Von Stockar; Ian W. Marison
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IRAK: A kinase associated with the interleukin-1 receptor
Science, ISSN: 00368075
Zhaodan Cao; William J. Henzel; Xiong Gao
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Biological and immunological characterization of inhibin forms in human plasma
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
Robertson; Burger; Sullivan; Cahir; Nigel P. Groome; Poncelet; Franchimont; Woodruff; Mather
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Decreased food intake does not completely account for adiposity reduction after ob protein infusion
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Nancy Levin; Nelson; Austin L. Gurney; Richard Vandleni; Frederic J. De Sauvage
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Strategies for manipulating apoptosis for cancer therapy with tumor necrosis factor and lymphotoxin
Journal of Cellular Biochemistry, ISSN: 07302312
Grace H.W. Wong; Roger L. Kaspar; Gary Zweiger; Carlson; Fong; Niloofar Ehsani; Gordon A. Vehar
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The Crystal Structure of the Extracellular Domain of Human Tissue Factor Refined to 1.7 Å Resolution
Journal of Molecular Biology, ISSN: 00222836
Yves A. Muller; Ultsch; De Vos
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HGF and HGF receptor expresion in the lacrimal gland
Investigative Ophthalmology and Visual Science, ISSN: 01460404
Mohan; Li; Weng; Bennett; Ralph H. Schwall; Wang; Tabor; Kim; Hargrave; Cuevas; Wilson
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Differential cardiac effects of growth hormone and insulin-like growth factor-1 in the rat: A combined in vivo and in vitro evaluation
Circulation, ISSN: 00097322
Antonio Cittadini; Hinrik Strömer; Sarah E. Katz; Ross Clark; Alan C. Moses; James P. Morgan; Pamela Douglas
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Tear Hepatocyte Growth Factor (HGF) production increases markedly after excimer laser photorefractive keratoplasty (PRK)
Investigative Ophthalmology and Visual Science, ISSN: 01460404
Qianwa Liang; Tervo; Vesaluoma; Bennett; Ralph H. Schwall; Marco Helena; Wilson
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Vascular endothelial growth factor promotes tumor dissemination by a mechanism distinct from its effect on primary tumor growth
Cancer Research, ISSN: 00085472
Ostap Melnyk; Shuman; K.Jin Kim
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Macrophage-mediated apoptosis in the developing mouse eye
Investigative Ophthalmology and Visual Science, ISSN: 01460404
Graciana Diez-Roux; Mark Labow; Horst Bluthman; Mark Moore; Richard Lang
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Isomerization of an aspartic acid residue in the complementarity-determining regions of a recombinant antibody to human IgE: Identification and effect on binding affinity
Biochemistry, ISSN: 00062960
Cacia; Rodney Keck; Presta; John Frenz
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A model for metal affinity protein precipitation
Journal of Colloid and Interface Science, ISSN: 00219797
Harish V. Iyer; Todd M. Przybycien
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Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway
Cell, ISSN: 00928674
Marco A. Meraz; J. Michael White; Kathleen C. Sheehan; Bach; Scott J. Rodig; Anand S. Dighe; Daniel H. Kaplan; Riley; Andrew C. Greenlund; Dayle Campbell; Karen Carver-Moore; Raymond N. DuBois; Ross Clark; Michel Aguet; Schreiber
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High level secretion of a humanized bispecific diabody from Escherichia coli
Bio/Technology, ISSN: 0733222X
Zhu; Gerardo Zapata; Shalaby; Snedecor; Man Chert; Paul J. Carter
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Physiological regulation of early and late stages of megakaryocytopoiesis by thrombopoietin
Journal of Experimental Medicine, ISSN: 00221007
Frederic J. De Sauvage; Karen Carver-Moore; Shiuh-Ming Luoh; Anne Ryan; Mary Dowd; Dan L. Eaton; Mark Moore
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The in vivo bioactivity of vascular endothelial growth factor/vascular permeability factor is independent of N-linked glycosylation
Laboratory Investigation, ISSN: 00236837
Dirk H. Walter; Uli Hink; Takayuki Asahara; Eric Van Belle; Jeffrey Horowitz; Yukio Tsurumi; Richard L. Vandlen; Heinsohn; Keyt; Napoleone Ferrara; James F. Symes; Jeffrey M. Isner
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Electrophoretic separation of recombinant tissue-type plasminogen activator glycoforms: Validation issues for capillary isoelectric focusing methods
Electrophoresis, ISSN: 01730835
Kathy Moorhouse; Carina A. Rickel; Chen
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Cardiotrophin-1 displays early expression in the murine heart tube and promotes cardiac myocyte survival
Development (Cambridge), ISSN: 09501991
Zelin Sheng; Diane Pennica; William I. Wood; Kenneth R. Chien
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Identification of a hepatocyte growth factor autocrine loop in a murine mammary carcinoma
Cell Growth and Differentiation, ISSN: 10449523
Nader Rahimi; Eric Tremblay; Laura McAdam; Marg Park; Ralph H. Schwall; Bruce Elliott
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Multiple immune abnormalities in tumor necrosis factor and lymphotoxin-α double-deficient mice
International Immunology, ISSN: 09538178
Hans-Pietro Eugster; Matthias Müller; Urs Karrer; Bruce D. Car; Bruno Schnyder; Vicki M. Eng; Gaetane Woerly; Michel Le Hir; Franco Di Padova; Michel Aguet; Rolf M. Zinkernagel; Horst Bluethmann; Bernhard Ryffel
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Hypoxia-induced paracrine regulation of vascular endothelial growth factor receptor expression
Journal of Clinical Investigation, ISSN: 00219738
Edi Brogi; Gina Schatteman; Tiangen Wu; Elizabeth A. Kim; Lyuba Varticovski; Keyt; Jeffrey M. Isner
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Hematopoietic defects in mice lacking the sialomucin CD34
Blood, ISSN: 00064971
Jill Cheng; Baumhueter; Cacalano; Karen Carver-Moore; Harold Thibodeaux; Thomas; Hal E. Broxmeyer; Cooper; Hague; Mark Moore; Lasky
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Hematopoietic defects in mice lacking the sialomucin CD34
Blood, ISSN: 00064971
Jill Cheng; Baumhueter; Cacalano; Karen Carver-Moore; Harold Thibodeaux; Thomas; Hal E. Broxmeyer; Scott Cooper; Hague; Mark Moore; Lasky
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Vascular endothelial growth factor augments muscle blood flow and function in a rabbit model of chronic hindlimb ischemia
Journal of Cardiovascular Pharmacology, ISSN: 01602446
Walder; Carol J. Errett; Bunting; Peter Lindquist; John R. Ogez; Heinsohn; Napoleone Ferrara; G. Roger Thomas
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Pharmacokinetics and pharmacodynamics of TP-9201, a gpIIbIIIa antagonist, administered in combination with recombinant tissue-type plasminogen activator, heparin, and aspirin in beagles
Journal of Cardiovascular Pharmacology, ISSN: 01602446
Modi; Theresa Reynolds; Sharon A. Baughman; Deborah A. Thomas; Paasch; Susan Yvonne Smith
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Binding in the growth hormone receptor complex
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
James A. Wells
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Structure of the saponin adjuvant QS-21 and its base-catalyzed isomerization product by 1 H and natural abundance 13 C NMR spectroscopy
Carbohydrate Research, ISSN: 00086215
Neil E. Jacobsen; Wayne J. Fairbrother; Kensil; Lim; Deborah A. Wheeler; Powell
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Structural elucidation of O-linked glycopeptides by high energy collision-induced dissociation
Journal of the American Society for Mass Spectrometry, ISSN: 10440305
Medzihradszky; Beth Gillece-Castro; Townsend; Alma Burlingame; Hardy
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Hepatocyte proliferation and serum hepatocyte growth factor levels in patients with alcoholic hepatitis
Journal of Hepatology, ISSN: 01688278
Kenneth J. Hillan; Martin C. Logan; Rod K. Ferrier; George L. Bird; Bennett; Ian C. McKay; Roderick N. M. MacSween
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Hematologically important mutations: X-Linked chronic granulomatous disease
Blood Cells, Molecules, and Diseases, ISSN: 10799796
Andrew R. Cross; John T. Curnutte; Julie Rae; Heyworth
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Regulation of transplacental virus infection by developmental and immunological factors: Studies with lactate dehydrogenase-elevating virus
Virus Research, ISSN: 01681702
Thomas R. Haven; Raymond R.R. Rowland; Peter G. W. Plagemann; Grace H.W. Wong; Sarahann E. Bradley; William A. Cafruny
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186Re-labeled antibodies to p185HER2 as HER2-targeted radioimmunopharmaceutical agents: Comparison of physical and biological characteristics with 125I and 131I-labeled counterparts
Cancer Biotherapy and Radiopharmaceuticals, ISSN: 10849785
Claire Kotts; Su; Cecilia Leddy; Dodd; Scates; Shalaby; Wirth; Giltinan; Schroff; Fritzberg; Shepard; Dennis J. Slamon; Hutchins
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Vascular endothelial growth factor, a specific regulator of angiogenesis
Current Opinion in Nephrology and Hypertension, ISSN: 10624821
Napoleone Ferrara; Bunting
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Follistatins and α2-macroglobulin are soluble binding proteins for inhibinand activin
Hormone Research, ISSN: 16632826 16632818
Mather
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GDNF induces a dystonia-like state in neonatal rats and stimulates dopamine and serotonin synthesis
Neuron, ISSN: 08966273
Klaus D. Beck; Ian Irwin; Janet Valverde; Thomas J. Brennan; J. William Langston; Franz Hefti
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Regulated release and polarized localization of brain-derived neurotrophic factor in hippocampal neurons
Molecular and Cellular Neuroscience, ISSN: 10447431
Goodman; Janet Valverde; Filip Lim; Michael D. Geschwind; Howard J. Federoff; Alfred I. Geller; Franz Hefti
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Locating the unpaired cysteine of tissue-type plasminogen activator
Protein Engineering, ISSN: 02692139
Louis C. Sehl; Hung V. Nguyen; Lea Berleau; Patricia Arcila; William F. Bennett; Keyt
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Human cardiotrophin-1: Protein and gene structure, biological and binding activities, and chromosomal localization
Cytokine, ISSN: 10434666
Diane Pennica; Todd A. Swanson; Kenneth J. Shaw; Wun-Jing Kuang; Christa Gray; Barbara G. Beatty; William I. Wood
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Liquid-liquid emulsification by rotor/stator homogenization
Journal of Controlled Release, ISSN: 01683659
Maa; Chung C. Hsu
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Multicopy suppressors of prc mutant Escherichia coli include two HtrA (DegP) protease homologs (HhoAB), DksA, and a truncated rlpA
Journal of Bacteriology, ISSN: 00219193
Bass; Qimin Gu; Anthony Christen
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Flux measurements across Caco-2 monolayers may predict transport in human large intestinal tissue
Journal of Pharmaceutical Sciences, ISSN: 00223549
Rubas; Cromwell; Shahrokh; Villagran; Nguyen; Wellton; Tue H. Nguyen; Mrsny
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Penicillamine: An extractable chiral auxiliary providing excellent stereocontrol
Tetrahedron Asymmetry, ISSN: 09574166
Lutz S. Richter; Thomas Gadek
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Protection of MN-rgp120-immunized chimpanzees from heterologous infection with a primary isolate of human immunodeficiency virus type 1
Journal of Infectious Diseases, ISSN: 00221899
Berman; Murthy; Wrin; Vennari; Kathy Cobb; Eastman; Mark Champe; Nakamura; Donna Davison; Powell; Bussiere; Francis; Matthews; Timothy Gregory; John F. Obijeski
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Gene targeting in neuroscience: The systemic approach
Trends in Neurosciences, ISSN: 01662236
Gerlai
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