Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 13651 - 13700 OF 16125 RESULTS

March 15, 1996

Protection against lethal Escherichia coli bacteremia in baboons (Papio anubis) by pretreatment with a 55-kDa TNF receptor (CD120a)-Ig fusion protein, Ro 45-2081

Journal of Immunology, ISSN: 00221767

Kimberly J. Van Zee; Lyle L. Moldawer; Hester S. A. Oldenburg; William A. Thompson; Sarah A. Stackpole; Walton J. Montegut; Michael A. Rogy; Carol Meschter; Harald Gallati; Claus-Dieter Schiller; Wolfgang F. Richter; Hansruedi Loetscher; Avi Ashkenazi; Steven M. Chamow; Florian M. Wurm; Steve E. Calvano; Stephen F. Lowry; Werner Lesslauer

March 15, 1996

Analysis of heregulin-induced ErbB2 phosphorylation with a high-throughput kinase receptor activation enzyme-linked immunosorbant assay

Analytical Biochemistry, ISSN: 00032697

Michael D Sadick; Mark X. Sliwkowski; Andrew Nuijens; Bald; Nancy Y. Chiang; Julie A. Lofgren; Wai Lee T. Wong

March 14, 1996

An integrated method to determine epithelial transport and bioactivity of oral drug candidates in vitro

Pharmaceutical Research, ISSN: 07248741

Rubas; Cromwell; Mrsny; Gladys S. Ingle; Kathleen A. Elias

March 13, 1996

Aggregation of rhDNase occurred during the compression of KBr pellets used for FTIR spectroscopy

Pharmaceutical Research, ISSN: 07248741

Chan; Ongpipattanakul; Jacky Au-Yeung

March 8, 1996

Identification of vascular endothelial growth factor determinants for binding KDR and FLT-1 receptors: Generation of receptor-selective VEGF variants by site-directed mutagenesis

Journal of Biological Chemistry, ISSN: 00219258

Keyt; Hung V. Nguyen; Lea Berleau; Carlos M. Duarte; Jeanie Park; Helen Chen; Napoleone Ferrara

March 8, 1996

Participation of JAK and STAT proteins in growth hormone-induced signaling

Journal of Biological Chemistry, ISSN: 00219258

Yulong Han; Douglas W. Leaman; Diane Watling; Neil C. Rogers; Bernd Groner; Ian M. Kerr; William I. Wood; George R. Stark

March 8, 1996

TAFII250 is a bipartite protein kinase that phosphorylates the basal transcription factor RAP74

Cell, ISSN: 00928674

Rivka Dikstein; Siegfried Ruppert; Robert Tjian

March 5, 1996

Vascular endothelial growth factor-related protein: A ligand and specific activator of the tyrosine kinase receptor Flt4

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

James Lee; Gray; Jean Q. Yuan; Shiuh-Ming Luoh; Hava Avraham; William I. Wood

March 1, 1996

The effect of variance function estimation on nonlinear calibration inference in immunoassay data

Biometrics, ISSN: 0006341X

Bruce A. Belanger; Davidian; Giltinan

March 1, 1996

The quaking gene product necessary in embryogenesis and myelination combines features of RNA binding and signal transduction proteins

Nature Genetics, ISSN: 10614036

Tom A. Ebersole; Qi Chen; Monica J. Justice; Karen Artzt

March 1, 1996

Transforming growth factor β1 induces angiogenesis in vivo with a threshold pattern

Laboratory Investigation, ISSN: 00236837

Luis F. Fajardo; Stavros D. Prionas; Helen H. Kwan; Joe Kowalski; Anthony C. Allison

March 1, 1996

Reproductive toxicity testing of therapeutic biotechnology agents

Teratology, ISSN: 00403709

Judith W. Henck; Kim G. Hilbish; Mercedes A. Serabian; Joy A. Cavagnaro; Andrew G. Hendrickx; Narsingh D. Agnish; Ada H.C. Kung; Joyce Mordenti

March 1, 1996

Critical amino acids in the lymphocyte function-associated antigen-1 I domain mediate intercellular adhesion molecule 3 binding and immune function

Journal of Experimental Medicine, ISSN: 00221007

Yvette Van Kooyk; Minke E. Binnerts; Caroline P. Edwards; Mark Champe; Berman; Carl G. Figdor; Bodary

March 1, 1996

Expression and regulation of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in distinct avian motoneuron subsets

Journal of Neurobiology, ISSN: 00223034

Nitza Kahane; David L. Shelton; Chaya Kalcheim

February 28, 1996

Systematic improvement of a chemically-defined protein-free medium for hybridoma growth and monoclonal antibody production

Journal of Biotechnology, ISSN: 01681656

Stoll; Mühlethaler; Von Stockar; Ian W. Marison

February 23, 1996

IRAK: A kinase associated with the interleukin-1 receptor

Science, ISSN: 00368075

Zhaodan Cao; William J. Henzel; Xiong Gao

February 20, 1996

Biological and immunological characterization of inhibin forms in human plasma

Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X

Robertson; Burger; Sullivan; Cahir; Nigel P. Groome; Poncelet; Franchimont; Woodruff; Mather

February 20, 1996

Decreased food intake does not completely account for adiposity reduction after ob protein infusion

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Nancy Levin; Nelson; Austin L. Gurney; Richard Vandleni; Frederic J. De Sauvage

February 16, 1996

Strategies for manipulating apoptosis for cancer therapy with tumor necrosis factor and lymphotoxin

Journal of Cellular Biochemistry, ISSN: 07302312

Grace H.W. Wong; Roger L. Kaspar; Gary Zweiger; Carlson; Fong; Niloofar Ehsani; Gordon A. Vehar

February 16, 1996

The Crystal Structure of the Extracellular Domain of Human Tissue Factor Refined to 1.7 Å Resolution

Journal of Molecular Biology, ISSN: 00222836

Yves A. Muller; Ultsch; De Vos

February 15, 1996

HGF and HGF receptor expresion in the lacrimal gland

Investigative Ophthalmology and Visual Science, ISSN: 01460404

Mohan; Li; Weng; Bennett; Ralph H. Schwall; Wang; Tabor; Kim; Hargrave; Cuevas; Wilson

February 15, 1996

Differential cardiac effects of growth hormone and insulin-like growth factor-1 in the rat: A combined in vivo and in vitro evaluation

Circulation, ISSN: 00097322

Antonio Cittadini; Hinrik Strömer; Sarah E. Katz; Ross Clark; Alan C. Moses; James P. Morgan; Pamela Douglas

February 15, 1996

Tear Hepatocyte Growth Factor (HGF) production increases markedly after excimer laser photorefractive keratoplasty (PRK)

Investigative Ophthalmology and Visual Science, ISSN: 01460404

Qianwa Liang; Tervo; Vesaluoma; Bennett; Ralph H. Schwall; Marco Helena; Wilson

February 15, 1996

Vascular endothelial growth factor promotes tumor dissemination by a mechanism distinct from its effect on primary tumor growth

Cancer Research, ISSN: 00085472

Ostap Melnyk; Shuman; K.Jin Kim

February 15, 1996

Macrophage-mediated apoptosis in the developing mouse eye

Investigative Ophthalmology and Visual Science, ISSN: 01460404

Graciana Diez-Roux; Mark Labow; Horst Bluthman; Mark Moore; Richard Lang

February 13, 1996

Isomerization of an aspartic acid residue in the complementarity-determining regions of a recombinant antibody to human IgE: Identification and effect on binding affinity

Biochemistry, ISSN: 00062960

Cacia; Rodney Keck; Presta; John Frenz

February 10, 1996

A model for metal affinity protein precipitation

Journal of Colloid and Interface Science, ISSN: 00219797

Harish V. Iyer; Todd M. Przybycien

February 9, 1996

Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

Cell, ISSN: 00928674

Marco A. Meraz; J. Michael White; Kathleen C. Sheehan; Bach; Scott J. Rodig; Anand S. Dighe; Daniel H. Kaplan; Riley; Andrew C. Greenlund; Dayle Campbell; Karen Carver-Moore; Raymond N. DuBois; Ross Clark; Michel Aguet; Schreiber

February 8, 1996

High level secretion of a humanized bispecific diabody from Escherichia coli

Bio/Technology, ISSN: 0733222X

Zhu; Gerardo Zapata; Shalaby; Snedecor; Man Chert; Paul J. Carter

February 1, 1996

Physiological regulation of early and late stages of megakaryocytopoiesis by thrombopoietin

Journal of Experimental Medicine, ISSN: 00221007

Frederic J. De Sauvage; Karen Carver-Moore; Shiuh-Ming Luoh; Anne Ryan; Mary Dowd; Dan L. Eaton; Mark Moore

February 1, 1996

The in vivo bioactivity of vascular endothelial growth factor/vascular permeability factor is independent of N-linked glycosylation

Laboratory Investigation, ISSN: 00236837

Dirk H. Walter; Uli Hink; Takayuki Asahara; Eric Van Belle; Jeffrey Horowitz; Yukio Tsurumi; Richard L. Vandlen; Heinsohn; Keyt; Napoleone Ferrara; James F. Symes; Jeffrey M. Isner

February 1, 1996

Electrophoretic separation of recombinant tissue-type plasminogen activator glycoforms: Validation issues for capillary isoelectric focusing methods

Electrophoresis, ISSN: 01730835

Kathy Moorhouse; Carina A. Rickel; Chen

February 1, 1996

Cardiotrophin-1 displays early expression in the murine heart tube and promotes cardiac myocyte survival

Development (Cambridge), ISSN: 09501991

Zelin Sheng; Diane Pennica; William I. Wood; Kenneth R. Chien

February 1, 1996

Identification of a hepatocyte growth factor autocrine loop in a murine mammary carcinoma

Cell Growth and Differentiation, ISSN: 10449523

Nader Rahimi; Eric Tremblay; Laura McAdam; Marg Park; Ralph H. Schwall; Bruce Elliott

January 31, 1996

Multiple immune abnormalities in tumor necrosis factor and lymphotoxin-α double-deficient mice

International Immunology, ISSN: 09538178

Hans-Pietro Eugster; Matthias Müller; Urs Karrer; Bruce D. Car; Bruno Schnyder; Vicki M. Eng; Gaetane Woerly; Michel Le Hir; Franco Di Padova; Michel Aguet; Rolf M. Zinkernagel; Horst Bluethmann; Bernhard Ryffel

January 15, 1996

Hypoxia-induced paracrine regulation of vascular endothelial growth factor receptor expression

Journal of Clinical Investigation, ISSN: 00219738

Edi Brogi; Gina Schatteman; Tiangen Wu; Elizabeth A. Kim; Lyuba Varticovski; Keyt; Jeffrey M. Isner

January 15, 1996

Hematopoietic defects in mice lacking the sialomucin CD34

Blood, ISSN: 00064971

Jill Cheng; Baumhueter; Cacalano; Karen Carver-Moore; Harold Thibodeaux; Thomas; Hal E. Broxmeyer; Cooper; Hague; Mark Moore; Lasky

January 15, 1996

Hematopoietic defects in mice lacking the sialomucin CD34

Blood, ISSN: 00064971

Jill Cheng; Baumhueter; Cacalano; Karen Carver-Moore; Harold Thibodeaux; Thomas; Hal E. Broxmeyer; Scott Cooper; Hague; Mark Moore; Lasky

January 11, 1996

Vascular endothelial growth factor augments muscle blood flow and function in a rabbit model of chronic hindlimb ischemia

Journal of Cardiovascular Pharmacology, ISSN: 01602446

Walder; Carol J. Errett; Bunting; Peter Lindquist; John R. Ogez; Heinsohn; Napoleone Ferrara; G. Roger Thomas

January 11, 1996

Pharmacokinetics and pharmacodynamics of TP-9201, a gpIIbIIIa antagonist, administered in combination with recombinant tissue-type plasminogen activator, heparin, and aspirin in beagles

Journal of Cardiovascular Pharmacology, ISSN: 01602446

Modi; Theresa Reynolds; Sharon A. Baughman; Deborah A. Thomas; Paasch; Susan Yvonne Smith

January 9, 1996

Binding in the growth hormone receptor complex

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

James A. Wells

January 4, 1996

Structure of the saponin adjuvant QS-21 and its base-catalyzed isomerization product by 1 H and natural abundance 13 C NMR spectroscopy

Carbohydrate Research, ISSN: 00086215

Neil E. Jacobsen; Wayne J. Fairbrother; Kensil; Lim; Deborah A. Wheeler; Powell

January 1, 1996

Experimental cerebral venous thrombosis: Evaluation using magnetic resonance imaging

Journal of Cerebral Blood Flow and Metabolism, ISSN: 0271678X

Joachim Röther; Kim Waggie; Nicholas Van Bruggen; De Crespigny; Michael Moseley

January 1, 1996

The treatment of systemic lupus erythematosus (SLE) in NZB/W F1 hybrid mice; studies with recombinant murine DNase and with dexamethasone

Clinical and Experimental Immunology, ISSN: 00099104

Macanovic; Sinicropi; Shak; Sharon A. Baughman; Thiru; Peter J. Lachmann

January 1, 1996

Limiting systemic plasminogenolysis reduces the bleeding potential for tissue-type plasminogen activators but not for streptokinase

Thrombosis and Haemostasis, ISSN: 03406245

G. Roger Thomas; Harold Thibodeaux; Carol J. Errett; Julie M. Badillo; Daisy T. Wu; Refino; Keyt; William F. Bennett

January 1, 1996

Sustained release of recombinant human growth hormone from dextran via hydrolysis of an imine bond

Journal of Controlled Release, ISSN: 01683659

John E. Battersby; Ross Clark; William S. Hancock; Estela Puchulu-Campanella; Neill Haggarty; Dick Poll; David Harding

January 1, 1996

Transcytosis of protein through the mammalian cerebral epithelium and endothelium. III. Receptor-mediated transcytosis through the blood-brain barrier of blood-borne transferrin and antibody against the transferrin receptor

Experimental Neurology, ISSN: 00144886

Richard D. Broadwell; Cairns; Phillip M. Friden; Constance Oliver; Juan C. Villegas

January 1, 1996

Antibody to native human immunodeficiency virus type 1 envelope glycoproteins induced by IIIB and MN recombinant gp120 vaccines

Clinical and Diagnostic Laboratory Immunology, ISSN: 1071412X

Geoffrey Gorse; Gira B. Patel; Frances K. Newman; Robert Belshe; Berman; Timothy Gregory; David Schwartz; Jack Lambert; Mary Lou Clements; Sharon E. Frey; Mark Mulligan; Edward Hook; Thomas Evans; Michael C. Keefer; Raphael Dolin; M. Juliana McElrath; Lawrence Corey; Barney S. Graham; Peter Wright; Matthews; Dani P. Bolognesi; James McNamara; Mary Clare Walker; Patricia Fast

January 1, 1996

Effects of 12-week administration of dornase alfa in patients with advanced cystic fibrosis lung disease

Chest, ISSN: 00123692

Karen McCoy; Scott A. Hamilton; Charles A. Johnson

January 1, 1996

Control of islet intercellular adhesion molecule-1 expression by interferon-α and hypoxia

Diabetes, ISSN: 00121797

Debasis Chakrabarti; Huang; Joanne T. Beck; Jill Henrich; Nancy McFarland; James; Stewart

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