Genentech: Publications

January 1, 2014

Effect of erlotinib on CYP3A activity, evaluated in vitro and by dual probes in patients with cancer

Anti-Cancer Drugs, ISSN: 14735741 09594973

Hilary Calvert; Chris Twelves; Malcolm Ranson; Ruth Plummer; Scott Fettner; Michael P. Pantze; Jie Ling; Marta Hamilton; Bert L. Lum; Ashok Rakhit

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January 1, 2014

Time to clinically significant visual acuity gains after ranibizumab treatment for retinal vein occlusion: BRAVO and CRUISE trials

Ophthalmology, ISSN: 15494713 01616420

Allen B. Thach; Linda Yau; Carol Hoang; Lisa Tuomi

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January 1, 2014

The production and regulation of IgE by the immune system

Nature Reviews Immunology, ISSN: 14741741 14741733

Lawren C. Wu; Ali A. Zarrin

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January 1, 2014

Innate lymphoid cells and asthma

Journal of Allergy and Clinical Immunology, ISSN: 10976825 00916749

Sanhong Yu; Hye Young Kim; Ya-Jen Chang; Rosemarie H. Dekruyff; Dale T. Umetsu

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January 1, 2014

Induction of ectopic taste buds by SHH reveals the competency and plasticity of adult lingual epithelium

Development (Cambridge), ISSN: 14779129 09501991

David Castillo; Kerstin Seidel; Ernesto Salcedo; Christina Ahn; Frederic J. De Sauvage; Ophir D. Klein; Linda A. Barlow

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January 1, 2014

Integrative analysis of two cell lines derived from a non-small-lung cancer patient - A panomics approach

19th Pacific Symposium on Biocomputing, PSB 2014, ISSN: 23356936 23356928

Oleg Mayba; Florian Gnad; Michael Peyton; Fan Zhang; Kimberly Walter; Pan Du; Melanie A. Huntley; Zhaoshi Jiang; Jinfeng Liu; Matthias Peter; Robert Gentleman; Ruiqiang Li; Minna; Yingrui Li; David S. Shames; Zemin Zhang

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January 1, 2014

An integrative analysis of colon cancer identifies an essential function for PRPF6 in tumor growth

Genes and Development, ISSN: 15495477 08909369

Adam S. Adler; Mark L. McCleland; Sharon Fong Yee; Murat Yaylaoglu; Sofia Hussain; Ely Cosino; Gabriel Quinones; Zora Modrusan; Somasekar Seshagiri; Eric Torres; Vivek S. Chopra; Benjamin Haley; Zemin Zhang; Elizabeth M. Blackwood; Mallika Singh; Melissa Junttila; Jean-Philippe Stephan; Jinfeng Liu; Gregoire Pau; Eric R. Fearon; Zhaoshi Jiang; Ron Firestein

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January 1, 2014

Dissecting gene expression at the blood-brain barrier

Frontiers in Neuroscience, ISSN: 1662453X 16624548

Melanie A. Huntley; Nga Bien-Ly; Richard Daneman; Ryan J. Watts

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January 1, 2014

A phase I study of the human monoclonal anti-NRP1 antibody MNRP1685A in patients with advanced solid tumors

Investigational New Drugs, ISSN: 15730646 01676997

Colin D. Weekes; Muralidhar Beeram; Anthony W. Tolcher; Kyriakos P. Papadopoulos; Lia Gore; Priti Hegde; Yan Xin; Ron Yu; L. Mason Shih; Hong Xiang; Rainer Brachmann; Amita Patnaik

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January 1, 2014

A brief overview of the 32nd annual STP symposium on the toxicologic pathology of the digestive tract and pancreas

Toxicologic Pathology, ISSN: 01926233 15331601

Dimitry Danilenko; Prashant R. Nambiar; Mark F. Cesta

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January 1, 2014

The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy

Nature, ISSN: 14764687 00280836

Baris Bingol; Joy S. Tea; Lilian Phu; Mike Reichelt; Corey Bakalarski; Qinghua Song; Oded Foreman; Donald S. Kirkpatrick; Morgan Sheng

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January 1, 2014

Small-Molecule library subset screening as an aid for accelerating lead identification

Journal of Biomolecular Screening, ISSN: 1552454X 10870571

Beresini; Yichin Liu; Timothy D. Dawes; Clark; Linda O. Elliott; Stephen Schmidt; Rebecca Turincio; Steven W Jones; Richard A. Rodriguez; Peter Thana; Daniel Hascall; Daniel P. Gross; Nicholas J. Skelton

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January 1, 2014

The effects of lebrikizumab in patients with mild asthma following whole lung allergen challenge

Clinical and Experimental Allergy, ISSN: 09547894 13652222

Heleen Scheerens; Joseph R. Arron; Zheng; Wendy Putnam; Erickson; David F. Choy; Harris; Lee; Jarjour; Matthews

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January 1, 2014

Trafficking of endosomal Toll-like receptors

Trends in Cell Biology, ISSN: 18793088 09628924

Bettina L. Lee; Gregory M. Barton

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January 1, 2014

Trastuzumab, in combination with carboplatin and docetaxel, does not prolong the QT interval of patients with HER2-positive metastatic or locally advanced inoperable solid tumors: Results from a phase Ib study

Cancer Chemotherapy and Pharmacology, ISSN: 14320843 03445704

Xu; Charles H. Redfern; Michael S. Gordon; Stephen M. Eppler; Bert L. Lum; Caroline Trudeau

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January 1, 2014

B cell homeostasis and follicle confines are governed by fibroblastic reticular cells

Nature Immunology, ISSN: 15292916 15292908

Viviana Cremasco; Matthew C. Woodruff; Lucas Onder; Jovana Cupovic; Janice M. Nieves-Bonilla; Frank A Schildberg; Jonathan Chang; Floriana Cremasco; Christopher J. Harvey; Kai Wucherpfennig; Burkhard Ludewig; Michael C. Carroll; Shannon J. Turley

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January 1, 2014

Incidence of central nervous system metastases in patients with HER2-positive metastatic breast cancer treated with pertuzumab, trastuzumab, and docetaxel: Results from the randomized phase III study CLEOPATRA

Annals of Oncology, ISSN: 15698041 09237534

Sandra M. Swain; Baselga; David W. Miles; Im; Quah; Lee; Javier Cortés

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January 1, 2014

Clinical benefit assessment of vismodegib therapy in patients with advanced basal cell carcinoma

Oncologist, ISSN: 1549490X 10837159

Brigitte Dréno; Nicole Basset-Seguin; Ivor Caro; Huibin Yue; Dirk Schadendorf

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January 1, 2014

Doubling down on the PI3k-AKT-mTOR pathway enhances the antitumor efficacy of PARP inhibitor in triple negative breast cancer model beyond BRCA-ness

Neoplasia (United States), ISSN: 14765586 15228002

Pradip De; Yuling Sun; Jennifer H. Carlson; Lori S. Friedman; Brian R. Leyland-Jones; Nandini Dey

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January 1, 2014

Semisynthetic model calibration for monitoring glucose in mammalian cell culture with in situ near infrared spectroscopy

Biotechnology and Bioengineering, ISSN: 10970290 00063592

Michael Milligan; Nicholas Lewin-Koh; Daniel A. Coleman; Adeyma Arroyo; Victor Saucedo

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January 1, 2014

Cytokine release assays: Current practices and future directions

Cytokine, ISSN: 10960023 10434666

Deborah Finco-Kent; Grimaldi; Fort; Walker; Kiessling; Wolf; Salcedo; Faggioni; Schneider; Ibraghimov; Scesney; Serna; Prell; Stebbings; Narayanan

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January 1, 2014

Erratum: Retrospective analysis of first-line anti-vascular endothelial growth factor treatment patterns in wet age-related macular degeneration (Advances in Therapy (2013) 30 (1111-1127) DOI: 10.1007/s12325-013-0078-4)

Advances in Therapy, ISSN: 0741238X 18658652

Stephen S. Johnston; Kathleen Wilson; Alice Huang; David Smith; Helen Varker; Adam Turpcu

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January 1, 2014

Inactivation of PI(3)K p110δ breaks regulatory T-cell-mediated immune tolerance to cancer

Nature, ISSN: 14764687 00280836

Khaled Ali; Dalya R. Soond; Roberto Piñeiro; Thorsten Hagemann; Wayne Pearce; Ee Lyn Lim; Hicham Bouabe; Cheryl L. Scudamore; Timothy Hancox; Heather Maecker; Lori S. Friedman; Martin Turner; Klaus Okkenhaug; Bart Vanhaesebroeck

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January 1, 2014

A two-in-one antibody engineered from a humanized interleukin 4 antibody through mutation in heavy chain complementarity-determining regions

mAbs, ISSN: 19420870 19420862

Chingwei V. Lee; Patrick Koenig; Fuh

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January 1, 2014

Development of a safety biomarker signature to detect hepatic sinusoidal dilation associated with an anti-DLL4 biotherapeutic

Biomarkers, ISSN: 13665804 1354750X

Jacqueline M. Tarrant; Sock-Cheng Lewin-Koh; Nicholas Lewin-Koh

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January 1, 2014

An allosteric switch for pro-HGF/Met signaling using zymogen activator peptides

Nature Chemical Biology, ISSN: 15524469 15524450

Kyle E. Landgraf; Micah Steffek; Quan; Jeffrey Tom; Christine Yu; Santell; Henry R. Maun; Eigenbrot; Lazarus

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January 1, 2014

Complementary methods for the identification of substrates of proteolysis

Methods in Enzymology, ISSN: 15577988 00766879

Victoria Pham; Veronica G. Anania; Qui Phung; Jennie R. Lill

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January 1, 2014

Bevacizumab and cyclosphosphamide, doxorubicin, vincristine and prednisone in combination for patients with peripheral T-cell or natural killer cell neoplasms: An Eastern Cooperative Oncology Group study (E2404)

Leukemia and Lymphoma, ISSN: 10292403 10428194

Kristen Ganjoo; Fangxin Hong; Sandra J. Horning; Randy D. Gascoyne; Yasodha Natkunam; Lode J. Swinnen; Thomas M. Habermann; Brad Kahl; Ranjana H. Advani

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January 1, 2014

Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis

Science, ISSN: 10959203 00368075

Min Lu; David Lawrence; Scot A. Marsters; Diego Acosta-Alvear; Philipp Kimmig; Aaron S. Mendez; Adrienne W. Paton; James C. Paton; Peter Walter; Avi Ashkenazi

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January 1, 2014

Impact of Asthma Exacerbations and Asthma Triggers on Asthma-related Quality of Life in Patients with Severe or Difficult-to-Treat Asthma

Journal of Allergy and Clinical Immunology: In Practice, ISSN: 22132198

Allan T. Luskin; Bradley E. Chipps; Lawrence Rasouliyan; Dave P. Miller; Tmirah Haselkorn; Alejandro Dorenbaum

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January 1, 2014

Prediction and modeling of effects on the QTc interval for clinical safety margin assessment, based on single-ascending-dose study data with AZD3839

Journal of Pharmacology and Experimental Therapeutics, ISSN: 15210103 00223565

Erik Sparve; Angelica Quartino; Maria Lüttgen; Karin Tunblad; Anna Teiling Gårdlund; Johanna Fälting; Robert Alexander; Jens Kågström; Linnea Sjödin; Alexander Bulgak; Ahmad Al-Saffar; Matthew Bridgland-Taylor; Chris Pollard; Michael D.B. Swedberg; Torbjörn Vik; Björn Paulsson

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January 1, 2014

Clinical burden and predictors of asthma exacerbations in patients on guideline-based steps 4-6 asthma therapy in the TENOR cohort

Journal of Allergy and Clinical Immunology: In Practice, ISSN: 22132198

William J. Calhoun; Tmirah Haselkorn; David R. Mink; Dave P. Miller; Alejandro Dorenbaum; Robert S. Zeiger

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January 1, 2014

Immunogenicity/Hypersensitivity of biologics

Toxicologic Pathology, ISSN: 01926233 15331601

Michael W. Leach; James B. Rottman; M. Benjamin Hock; Deborah Finco-Kent; Jennifer L. Rojko; Joseph Beyer

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January 1, 2014

Clinical trial data sharing: From principles to practical implementation - An industry model

Regulatory Rapporteur, ISSN: 17428955

Sabine Atzor; Jonathan Sorof; Ariella Kelman; Pauline Parry; Maria-Theresia Rose; Albert Jan Schutte; Shahzamani; Rebecca Sudlow; Michael Vesik; Michael Doherty

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January 1, 2014

Viral clearance requirement for cell-line derived biologics at different stages of development

Chinese Journal of New Drugs, ISSN: 10033734

Qi Chen; Min Zhang; Bin Yang; Philip M. Lester

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January 1, 2014

Single-dose pharmacokinetics of the HCV polymerase inhibitor mericitabine in healthy Caucasian and Japanese subjects

Drug Metabolism and Pharmacokinetics, ISSN: 18800920 13474367

Carla Washington; Sebastian A. Moreira; Joshua Haznedar; Petra Goelzer; Ya-Chi Chen

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January 1, 2014

Global, regional, and national incidence and mortality for HIV, tuberculosis, and malaria during 1990-2013: A systematic analysis for the Global Burden of Disease Study 2013

The Lancet, ISSN: 1474547X 01406736

Christopher J.L. Murray; Katrina F. Ortblad; Caterina Guinovart; Stephen Lim; Timothy M. Wolock; David Allen Roberts; Emily Dansereau; Nicholas Graetz; Ryan M. Barber; Jonathan Brown; Haidong Wang; Herbert Duber; Mohsen Naghavi; Daniel Dicker; Lalit Dandona; Joshua A. Salomon; Kyle R. Heuton; Kyle J. Foreman; David Phillips; Thomas Fleming; Abraham Flaxman; Bryan Phillips; Elizabeth K. Johnson; Megan Coggeshall; Foad Abd-Allah; Semaw F. Abera; Jerry P. Abraham; Ibrahim Abubakar; Laith J. Abu-Raddad; Niveen M.E. Abu-Rmeileh; Tom Achoki; Austine Olufemi Adeyemo; Arsène K. Adou; Josef C. Adsuar; Emilie E. Agardh; Dickens Akena; Mazin J. Al Kahbouri; Deena Alasfoor; Mohammed I. Albittar; Alcalá-Cerra; Miguel A. Alegretti; Zewdie A. Alemu; Rafael Alfonso-Cristancho; Samia Alhabib; Raghib Ali; Francois Alla; Peter J. Allen; Ubai Alsharif; Elena Alvarez; Nelson Alvis-Guzman; Adansi A. Amankwaa; Azmeraw T. Amare; Heresh Amini; Walid Ammar; Benjamin O. Anderson; Carl Abelardo T. Antonio; Palwasha Anwari; Johan Arnlov; Valentina S. Arsic Arsenijevic; Al Artaman; Rana J. Asghar; Reza Assadi; Lydia S. Atkins; Alaa Badawi; Kalpana Balakrishnan; Amitava Banerjee; Sanjay Basu; Justin Beardsley; Tolesa Bekele; Michelle L. Bell; Eduardo Bernabe; Tariku Jibat Beyene; Neeraj Bhala; Ashish Bhalla; Zulfiqar Bhutta; Aref Bin Abdulhak; Agnes Binagwaho; Jed D. Blore; Berrak Bora Basara; Dipan Bose; Michael Brainin; Nicholas J.K. Breitborde; Carlos A. Castaneda-Orjuela; Ferran Catala-Lopez; Vineet K. Chadha; Jung-Chen Chang; Peggy P. Chiang; Pablo M. Lavados; Mercedes Colomar; Christian Kieling; Cyrus Cooper; Karen Courville; Benjamin C. Cowie; Michael H. Criqui; Rakhi Dandona; Anand Dayama; Diego De Leo; Louisa Degenhardt; Borja Del Pozo-Cruz; Kebede Deribe; Don C. Des Jarlais; Muluken Dessalegn; Samath D. Dharmaratne; Uur Dilmen; Eric L. Ding; Tim R. Driscoll; Adnan M. Durrani; Richard G. Ellenbogen; Sergey P. Ermakov; Alireza Esteghamati; Emerito Jose A. Faraon; Farshad Farzadfar; Seyed-Mohammad Fereshtehnejad; Daniel Obadare Fijabi; Mohammad H. Forouzanfar; Urbano Fra. Paleo; Lynne Gaffikin; Amiran Gamkrelidze; Fortune G. Gankpe; Johanna M. Geleijnse; Bradford D. Gessner; Katherine B. Gibney; Ibrahim A. Ginawi; Elizabeth L. Glaser; Philimon Gona; Atsushi Goto; Hebe N. Gouda; Harish C. Gugnani; Rajeev Gupta; Rahul Gupta; Nima Hafezi-Nejad; Randah R. Hamadeh; Mouhanad Hammami; Graeme J. Hankey; Hilda L. Harb; Josep Maria Haro; Rasmus Havmoeller; Simon Hay; Mohammad T. Hedayati; Ileana B. Heredia Pi; Hans W. Hoek; John Hornberger; Francis A. Mhimbira; Peter J. Hotez; Damian G. Hoy; John J. Huang; Kim M. Iburg; Bulat T. Idrisov; Kaire Innos; Kathryn H. Jacobsen; Panniyammakal Jeemon; Paul N. Jensen; Vivekanand Jha; Guohong Jiang; Jost B. Jonas; Knud Juel; Haidong Kan; Ida Kankindi; Karam; Andre Karch; Corine Kakizi Karema; Anil Kaul; Norito Kawakami; Dhruv S. Kazi; Andrew H. Kemp; Andre P. Kengne; Andre Keren; Maia Kereselidze; Yousef S. Khader; Shams Eldin A.H. Khalifa; Ejaz A. Khan; Young-Ho Khang; Irma Khonelidze; Yohannes Kinfu; Jonas M. Kinge; Luke Knibbs; Yoshihiro Kokubo; Soewarta Kosen; Barthelemy Kuate Defo; Veena S. Kulkarni; Chanda Kulkarni; Kaushalendra Kumar; Ravi B. Kumar; G Anil Kumar; Gene F. Kwan; Taavi Lai; Arjun Lakshmana Balaji; Hilton Lam; Qing Lan; Van C. Lansingh; Heidi Larson; Anders Larsson; Jong-Tae Lee; James Leigh; Mall Leinsalu; Ricky Leung; Yichong Li; Yongmei Li; Graça Maria Ferreira De Lima; Hsien-Ho Lin; Steven E. Lipshultz; Shiwei Liu; Yang Liu; Belinda K. Lloyd; Paulo A. Lotufo; Vasco Manuel Pedro Machado; Jennifer H. MacLachlan; Carlos Magis-Rodriguez; Marek Majdan; Christopher C. Mapoma; Wagner Marcenes; Melvin B. Marzan; Joseph R. Masci; Mohammad Taufiq Mashal; Amanda J. Mason-Jones; Bongani M. Mayosi; Tasara T. Mazorodze; Abigail C. McKay; Peter A. Meaney; Man Mohan Mehndiratta; Fabiola Mejia-Rodriguez; Yohannes A. Melaku; Ziad A. Memish; Walter Mendoza; Ted R. Miller; Edward J. Mills; Karzan A. Mohammad; Ali H. Mokdad; Glen L. Mola; Lorenzo Monasta; Marcella Montico; Ami R. Moore; Rintaro Mori; Wilkister N. Moturi; Mitsuru Mukaigawara; Kinnari S. Murthy; Aliya Naheed; Kovin S. Naidoo; Luigi Naldi; Vinay Nangia; K.M. Venkat Narayan; Denis Nash; Chakib Nejjari; Robert G. Nelson; Sudan P. Neupane; Charles R. Newton; Marie Ng; Muhammad I. Nisar; Sandra Nolte; Ole F. Norheim; Vincent Nowaseb; Luke Nyakarahuka; In Hwan Oh; Takayoshi Ohkubo; Bolajoko O. Olusanya; Saad B. Omer; John Nelson Opio; Orish Ebere Orisakwe; Jeyaraj D. Pandian; Christina Papachristou; Angel J. Paternina Caicedo; Scott B. Patten; Vinod K. Paul; Boris I. Pavlin; Neil Pearce; David M. Pereira; Aslam Pervaiz; Konrad Pesudovs; Max Petzold; Farshad Pourmalek; Dima Qato; Amado D. Quezada; Quistberg; Anwar Rafay; Kazem Rahimi; Vafa Rahimi-Movaghar; Sajjad Ur Rahman; Murugesan Raju; Saleem M. Rana; Homie Razavi; Robert Quentin Reilly; Giuseppe Remuzzi; Jan Hendrik Richardus; Luca Ronfani; Nobhojit Roy; Nsanzimana Sabin; Mohammad Yahya Saeedi; Mohammad Ali Sahraian; Genesis May J. Samonte; Monika Sawhney; Ione J.C. Schneider; David C. Schwebel; Soraya Seedat; Sadaf G. Sepanlou; Edson E. Servan-Mori; Sara Sheikhbahaei; Kenji Shibuya; Hwashin Hyun Shin; Ivy Shiue; Rupak Shivakoti; Inga D. Sigfusdottir; Donald H. Silberberg; Andrea P. Silva; Edgar P. Simard; Jasvinder A. Singh; Vegard Skirbekk; Karen Sliwa; Samir Soneji; Sergey S. Soshnikov; Chandrashekhar T. Sreeramareddy; Vasiliki Kalliopi Stathopoulou; Konstantinos Stroumpoulis; Soumya Swaminathan; Bryan L. Sykes; Karen M. Tabb; Roberto Tchio Talongwa; Eric Yeboah Tenkorang; Abdullah Sulieman Terkawi; Alan J. Thomson; Andrew L. Thorne-Lyman; Charles D.A. Wolfe; Jefferson Traebert; Bach X. Tran; Zacharie Tsala Dimbuene; Miltiadis K. Tsilimbaris; Uche S. Uchendu; Kingsley N. Ukwaja; Selen B. Uzun; Andrew J. Vallely; Tommi J. Vasankari; Narayanaswamy Venketasubramanian; Francesco S. Violante; Vasiliy Victorovich Vlassov; Stein Emil Vollset; Stephen Waller; Mitchell T. Wallin; Linhong Wang; XiaoRong Wang; Yanping Wang; Scott Weichenthal; Elisabete Weiderpass; Robert G. Weintraub; Ronny Westerman; Richard A. White; James D. Wilkinson; Thomas N. Williams; Solomon M. Woldeyohannes; John Q. Wong; Gelin Xu; Yang C. Yang; Yuichiro Yano; Gokalp K. Yentur; Paul Yip; Naohiro Yonemoto; Seok-Jun Yoon; Mustafa Younis; Chuanhua Yu; Kim Yun Jin; Maysaa El Sayed Zaki; Yong Zhao; Yingfeng Zheng; Maigeng Zhou; Jun Zhu; Xiao Nong Zou; Alan D. Lopez; Theo Vos

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January 1, 2014

Development and optimization of a high-throughput assay to measure neutralizing antibodies against clostridium difficile binary toxin

Clinical and Vaccine Immunology, ISSN: 1556679X 15566811

Jinfu Xie; Melanie Horton; Julie Zorman; Joseph M. Antonello; Yuhua Zhang; Beth A. Arnold; Susan Secore; Rachel Xoconostle; Matthew Miezeiewski; Su Wang; Colleen E. Price; David Thiriot; Aaron Goerke; Marie-Pierre Gentile; Julie M. Skinner; Jon H. Heinrichs

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January 1, 2014

Phenotypes determined by cluster analysis in severe or difficult-to-treat asthma

Journal of Allergy and Clinical Immunology, ISSN: 10976825 00916749

Michael Schatz; Jin-Wen Y. Hsu; Robert S. Zeiger; Wansu Chen; Alejandro Dorenbaum; Bradley E. Chipps; Tmirah Haselkorn

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January 1, 2014

Characterization of in vitro antibody-dependent cell-mediated cytotoxicity activity of therapeutic antibodies - Impact of effector cells

Journal of Immunological Methods, ISSN: 18727905 00221759

Shan Chung; Yuwen L. Lin; Chae Reed; Carl Ng; Zhijie Jey Cheng; Fabio Malavasi; Yang; Quarmby; An Song

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January 1, 2014

Dendritic cells in IBD pathogenesis: An area of therapeutic opportunity?

Journal of Pathology, ISSN: 00223417 10969896

Jennifer Bates; Laurie Diehl

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January 1, 2014

Reduced Insulin/IGF-1 Signaling Restores Germ Cell Immortality to Caenorhabditis elegans Piwi Mutants

Cell Reports, ISSN: 22111247

Matt Simon; Peter Sarkies; Kohta Ikegami; Anna-Lisa Doebley; Leonard D. Goldstein; Jacinth Mitchell; Aisa Sakaguchi; Eric A. Miska; Shawn Ahmed

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January 1, 2014

HGF/MET-directed therapeutics in gastroesophageal cancer: A review of clinical and biomarker development

Oncotarget, ISSN: 19492553

Stephen P. Hack; Jean-Marie Bruey; Koeppen

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January 1, 2014

Developing biomarkers to predict benefit from HGF/MET pathway inhibitors

Journal of Pathology, ISSN: 00223417 10969896

Koeppen; Sandra Rost; Robert Yauch

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January 1, 2014

Assay formats: Recommendation for best practices and harmonization from the global bioanalysis consortium harmonization team

AAPS Journal, ISSN: 15507416

Sherri Dudal; Daniel Baltrukonis; Rebecca Crisino; M. Jaya Goyal; Alison Joyce; Karolina Österlund; John Smeraglia; Yoshitaka Taniguchi; Yang

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January 1, 2014

CNS Amyloid-β, Soluble APP-α and-β Kinetics during BACE Inhibition

Journal of Neuroscience, ISSN: 15292401 02706474

Justyna A. Dobrowolska; Maria S. Michener; Guoxin Wu; Bruce W. Patterson; Robert Chott; Vitaliy Ovod; Yuriy Pyatkivskyy; Kristin R. Wildsmith; Tom Kasten; Parker Mathers; Mandy Dancho; Christina Lennox; Brad E. Smith; David Gilberto; Debra McLoughlin; Daniel J. Holder; Andrew W. Stamford; Kevin E. Yarasheski; Matthew E. Kennedy; Mary J. Savage; Randall J. Bateman

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January 1, 2014

Best practices for the development, scale-up, and post-approval change control of IR and MR dosage forms in the current quality-by-design paradigm

AAPS PharmSciTech, ISSN: 15309932

Glenn A. Van Buskirk; Satish Asotra; Christopher Balducci; Prabir Basu; Gerald DiDonato; Angelica Dorantes; W. Mark Eickhoff; Tapash Ghosh; Mario A. González; Theresa Henry; Matthew Howard; Jason Kamm; Steven Laurenz; Ryan MacKenzie; Richard Mannion; Patrick K. Noonan; Terrance Ocheltree; Umesh Pai; Richard P. Poska; Michael L. Putnam; Ramani R. Raghavan; Colleen Ruegger; Eric Sánchez; Vinod Shah; Zezhi Jesse Shao; Russell Somma; Vijay Tammara; Avinash G. Thombre; Bruce Thompson; Robert J. Timko; Satyam Upadrashta; Sivakumar Vaithiyalingam

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January 1, 2014

A Phase Ib study evaluating MNRP1685A, a fully human anti-NRP1 monoclonal antibody, in combination with bevacizumab and paclitaxel in patients with advanced solid tumors

Cancer Chemotherapy and Pharmacology, ISSN: 14320843 03445704

Amita Patnaik; Patricia M. LoRusso; Wells A. Messersmith; Kyriakos P. Papadopoulos; Lia Gore; Muralidhar Beeram; Vanitha Ramakrishnan; Amy H. Kim; Joseph Beyer; Mason Shih; Darbonne; Yan Xin; Ron Yu; Hong Xiang; Rainer Brachmann; Colin D. Weekes

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January 1, 2014

The other randomization - methods for labeling drug kits

Contemporary Clinical Trials, ISSN: 15592030 15517144

Daniel A. Coleman; Ron Yu

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January 1, 2014

Regulation of vascular endothelial junction stability and remodeling through Rap1-Rasip1 signaling

Cell Adhesion and Migration, ISSN: 19336926 19336918

Christopher W. Wilson; Weilan Ye

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