Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 9351 - 9400 OF 15795 RESULTS

Cardiovascular events associated with ipratropium bromide in COPD
Chest, ISSN: 19313543 00123692
Sarika S. Ogale; Todd A. Lee; David H. Au; Denise M. Boudreau; Sean D. Sullivan
View on Scopus
A valid equation for the well-stirred perfusion limited physiologically based pharmacokinetic model that consistently accounts for the blood-tissue drug distribution in the organ and the corresponding valid equation for the steady state volume of distribution
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Leonid M. Berezhkovskiy
View on Scopus
Psychological effects of patient surge in large-scale emergencies: A quality improvement tool for hospital and clinic capacity planning and response
Prehospital and Disaster Medicine, ISSN: 19451938 1049023X
Lisa S. Meredith; James L. Zazzali; Sandra Shields; David P. Eisenman; Halla Alsabagh
View on Scopus
A multigene predictor of outcome in glioblastoma
Neuro-Oncology, ISSN: 15228517 15235866
Howard Colman; Li Zhang; Erik P. Sulman; J. Matthew McDonald; Nasrin Latif Shooshtari; Andreana Rivera; Sonya Popoff; Catherine L. Nutt; David N. Louis; J. Gregory Cairncross; Mark R. Gilbert; Phillips; Minesh P. Mehta; Arnab Chakravarti; Christopher E. Pelloski; Krishna P.L. Bhat; Burt G. Feuerstein; Robert B. Jenkins; Kenneth D. Aldape
View on Scopus
Cold denaturation of monoclonal antibodies
mAbs, ISSN: 19420862
Kristi L. Lazar; Thomas W. Patapoff; Vikas Sharma
View on Scopus
Targeting mitochondrial glutaminase activity inhibits oncogenic transformation
Cancer Cell, ISSN: 15356108
Jian-Bin Wang; Jon W. Erickson; Reina N. Fuji; Sekar Ramachandran; Ping Gao; Ramani Dinavahi; Kristin F. Wilson; Andre L.B. Ambrosio; Sandra M.G. Dias; Chi V. Dang; Richard A. Cerione
View on Scopus
Bevacizumab safety in patients with central nervous system metastases
Clinical Cancer Research, ISSN: 10780432
Benjamin Besse; Susan F. Lasserre; Peter Compton; Jane E. Huang; Stella Augustus; Ulrich-Peter Rohr
View on Scopus
Therapeutic strategies within the ubiquitin proteasome system
Cell Death and Differentiation, ISSN: 13509047 14765403
Adam G. Eldridge; Thomas O'Brien
View on Scopus
Long-term safety of recombinant human growth hormone in children
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X 0021972X
Jennifer J. Bell; Parker; Rita D. Swinford; Andrew R. Hoffman; Thomas J. Maneatis; Barbara M. Lippe
View on Scopus
Regulation of death receptor signaling by the ubiquitin system
Cell Death and Differentiation, ISSN: 13509047 14765403
Ingrid E. Wertz; Vishva M. Dixit
View on Scopus
Crystal structures of IL-2-inducible T cell kinase complexed with inhibitors: Insights into rational drug design and activity regulation
Chemical Biology and Drug Design, ISSN: 17470285 17470277
Alan K. Kutach; Armando G. Villaseñor; Diana Lam; Charles Belunis; Cheryl Janson; Stephen Lok; Li-Na Hong; Chao-Min Liu; Jerome Deval; Thomas J. Novak; Jim W. Barnett; Wei Chu; David Shaw; Andreas Kuglstatter
View on Scopus
Efficacy and safety of rituximab in moderately-to-severely active systemic lupus erythematosus: The randomized, double-blind, phase II/III systemic lupus erythematosus evaluation of rituximab trial
Arthritis and Rheumatism, ISSN: 00043591 15290131
Merrill; C. Michael Neuwelt; Daniel J. Wallace; Joseph C. Shanahan; Latinis; James C. Oates; Tammy O. Utset; Gordon; David A. Isenberg; Hsin-Ju Hsieh; David Zhang; Paul Brunetta
View on Scopus
Hijacking HES1: how tumors co-opt the anti-differentiation strategies of quiescent cells
Trends in Molecular Medicine, ISSN: 14714914
Liyun Sang; James M. Roberts; Hilary A. Coller
View on Scopus
Poor disease control among insured users of high-dose combination therapy for asthma
Allergy and Asthma Proceedings, ISSN: 10885412 15396304
Michael S. Broder; Eunice Chang; Tripthi V. Kamath; Sandhya Sapra
View on Scopus
Purification and characterization of a motility initiating protein from caprine epididymal plasma
Journal of Cellular Physiology, ISSN: 00219541
Bijay S. Jaiswal; Kaushik Das; Sudipta Saha; Sandhya Rekha Dungdung; Gopal C. Majumder
View on Scopus
AF-353, a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist
British Journal of Pharmacology, ISSN: 14765381 00071188
Joel R. Gever; Rothschild Soto; Robert A. Henningsen; Renee S. Martin; David Hackos; Sandip Panicker; Rubas; Ian B. Oglesby; Michael P. Dillon; Marcos E. Milla; Geoffrey Burnstock; Anthony P. D. W. Ford
View on Scopus
Local tissue distribution and cellular fate of vascular endothelial growth factor (VEGF) following intramuscular injection
Journal of Drug Targeting, ISSN: 1061186X 10292330
Daugherty; Mrsny
View on Scopus
Structural characterization of intact antibodies by high-resolution LTQ Orbitrap mass spectrometry
Journal of Mass Spectrometry, ISSN: 10765174 10969888
Jennifer Zhang; Hongbin Liu; Viswanatham Katta
View on Scopus
Mechanism-based receptor-binding model to describe the pharmacokinetic and pharmacodynamic of an anti-α5β1 integrin monoclonal antibody (volociximab) in cancer patients
Cancer Chemotherapy and Pharmacology, ISSN: 03445704
Chee Ng; Shuang Bai; Takimoto; Meina Tao Tang; Anthony W. Tolcher
View on Scopus
Prospects for personalized medicine with inhibitors targeting the RAS and PI3K pathways
Expert Review of Molecular Diagnostics, ISSN: 14737159 17448352
Lackner
View on Scopus
Cell culture monitoring via an auto-sampler and an integrated multi-functional off-line analyzer
Biotechnology Progress, ISSN: 87567938 15206033
Gayle E. Derfus; Daniel Abramzon; Meg Tung; David Chang; Robert Kiss; Ashraf Amanullah
View on Scopus
Guidelines for reporting the use of capillary electrophoresis in proteomics
Nature Biotechnology, ISSN: 15461696 10870156
Paula J. Domann; Satoko Akashi; Coral Barbas; Lihua Huang; Wendy Lau; Cristina Legido-Quigley; Stephen McClean; Christian Neusü; David Perrett; Milena Quaglia; Erdmann Rapp; Lance Smallshaw; Norman W. Smith; W Franklin Smyth; Chris Taylor
View on Scopus
Phase 1 study of aflibercept administered subcutaneously to patients with advanced solid tumors
Clinical Cancer Research, ISSN: 10780432
William P. Tew; Michael S. Gordon; John Murren; Jakob Dupont; Sandra Pezzulli; Carol Aghajanian; Paul Sabbatini; David Mendelson; Lawrence Schwartz; Scott Gettinger; Amanda Psyrri; Jesse M. Cedarbaum; David R. Spriggs
View on Scopus
Immunization responses in rheumatoid arthritis patients treated with rituximab: Results from a controlled clinical trial
Arthritis and Rheumatism, ISSN: 00043591 15290131
Bingham; R. John Looney; Deodhar; Neal Halsey; Maria Greenwald; Christine Codding; Benjamin L. Trzaskoma; Flavius Martin; Sunil Agarwal; Ariella Kelman
View on Scopus
A two-stage algorithm for designing phase I cancer clinical trials for two new molecular entities
Contemporary Clinical Trials, ISSN: 15517144
Zheng Su
View on Scopus
B-cell activation influences T-cell polarization and outcome of anti-CD20 B-cell depletion in central nervous system autoimmunity
Annals of Neurology, ISSN: 15318249 03645134
Martin Weber; Thomas Prod'homme; Juan C. Patarroyo; Nicolas Molnarfi; Tara Karnezis; Klaus Lehmann-Horn; Dimitry Danilenko; Jeffrey Eastham-Anderson; Anthony J. Slavin; Christopher Linington; Claude C.A. Bernard; Flavius Martin; Scott S. Zamvil
View on Scopus
The conserved bardet-biedl syndrome proteins assemble a coat that traffics membrane proteins to Cilia
Cell, ISSN: 00928674
Hua Jin; Susan Roehl White; Toshinobu Shida; Stefan Schulz; Mike Aguiar; Steven P. Gygi; J.Fernando Bazan; Maxence V. Nachury
View on Scopus
Inflammasome-dependent release of the alarmin HMGB1 in endotoxemia
Journal of Immunology, ISSN: 15506606 00221767
Lamkanfi; Anasuya Sarkar; Vande Walle; Alberto C. Vitari; Amal O. Amer; Mark D. Wewers; Kevin J. Tracey; Thirumala-Devi Kanneganti; Vishva M. Dixit
View on Scopus
Pharmaceutical medical information contact centers: Results of three benchmarking surveys
Drug Information Journal, ISSN: 00928615
Pete Guillot; Stacey M. Fung
View on Scopus
Semi-automated protein binding methodology using equilibrium dialysis and a novel mixed-matrix cassette approach
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Emile G. Plise; Daniel Tran; Laurent Salphati
View on Scopus
Factors affecting the viscosity in high concentration solutions of different monoclonal antibodies
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Sandeep Yadav; Steven J. Shire; Devendra S. Kalonia
View on Scopus
Standardizing rodent trimming and embedding guidelines for histology: Improving efficiency in the laboratory
Journal of Histotechnology, ISSN: 01478885
Monika Larson; Taylor; Marjie Van Hoy
View on Scopus
Surface expression of precursor N-cadherin promotes tumor cell invasion
Neoplasia (United States), ISSN: 14765586 15228002
Deborah Maret; Eugenia Gruzglin; Mohamad Seyed Sadr; Vincent Siu; Shan; Alexander W. Koch; Nabil G. Seidah; Rolando F. del Maestro; David R. Colman
View on Scopus
Molecular mechanisms of regulatory T cell development and suppressive function
Progress in Molecular Biology and Translational Science, ISSN: 18771173
Kim
View on Scopus
Cell biology redux.
Molecular Biology of the Cell, ISSN: 19394586
Ira Mellman
View on Scopus
Molecular biomarker analyses using circulating tumor cells
PLoS ONE, ISSN: 19326203
Elizabeth A. Punnoose; Siminder Atwal; Jill M. Spoerke; Heidi Savage; Ajay Pandita; Ru-Fang Yeh; Andrea Pirzkall; Bernard M. Fine; Lukas Amler; Daniel S. Chen; Lackner
View on Scopus
Questions about coverage accompany new fully implantable hearing system
Managed Care, ISSN: 10623388
Thomas Morrow
View on Scopus
On the possibility of self-induction of drug protein binding
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Leonid M. Berezhkovskiy
View on Scopus
Randomized, double-masked, sham-controlled trial of ranibizumab for neovascular age-related macular degeneration: PIER study year 2
American Journal of Ophthalmology, ISSN: 00029394
Prema Abraham; Huibin Yue; Laura J. Wilson
View on Scopus
Structure of the Complex between HER2 and an Antibody Paratope Formed by Side Chains from Tryptophan and Serine
Journal of Molecular Biology, ISSN: 00222836
Robert D. Fisher; Ultsch; Andreas Lingel; Gabriele Schaefer; Lily Shao; Sara Birtalan; Sachdev S. Sidhu; Eigenbrot
View on Scopus
Effect of temperature, pH, dissolved oxygen, and hydrolysate on the formation of triple light chain antibodies in cell culture.
Biotechnology Progress, ISSN: 15206033
Natalia Gomez; Jun Ouyang; Mary D. H. Nguyen; Abigail R Vinson; Andy Lin; Inn H. Yuk
View on Scopus
Monoclonal antibody purification using cationic polyelectrolytes: an alternative to column chromatography.
Biotechnology Progress, ISSN: 15206033
Thanmaya Peram; Paul McDonald; Jayme N. Carter-Franklin; Fahrner
View on Scopus
Treatment outcomes by tumor histology in eastern cooperative group study E4599 of bevacizumab with paclitaxel/carboplatin for advanced non-small cell lung cancer
Journal of Thoracic Oncology, ISSN: 15561380 15560864
Alan Sandler; Jing Yi; Suzanne Dahlberg; Margaret M. Kolb; Lisa I. Wang; Julie Hambleton; Joan H. Schiller; David H. Johnson
View on Scopus
Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency
Nature Genetics, ISSN: 15461718 10614036
Ricardo C. Ferreira; Qiang Pan-Hammarström; Robert R. Graham; Vesela Gateva; Gumersindo Fontán; Annette T. Lee; Ward Ortmann; Elena Urcelay; Miguel Fernández-Arquero; Concepción Núñez; Gudmundur Jorgensen; Björn R. Ludviksson; Sinikka Koskinen; Katri Haimila; Hilary F. Clark; Lars Klareskog; Peter K. Gregersen; Timothy W. Behrens; Lennart Hammarström
View on Scopus
Anti-CD22-MCC-DM1: An antibody-drug conjugate with a stable linker for the treatment of non-Hodgkin's lymphoma
Leukemia, ISSN: 14765551 08876924
Andrew G. Polson; Marna Williams; Gray; Reina N. Fuji; Kirsten Achilles Poon; Jacqueline McBride; Helga Raab; Thomas Januario; MaryAnn Go; Jeffrey Lau; Shang-Fan Yu; Du; Franklin Fuh; Christine Tan; Yan Wu; Wei-Ching Liang; Saileta Prabhu; Jean-Philippe Stephan; Hongo; Randall Dere; Rong Deng; Cullen; Ruth De Tute; Bennett; Andy Rawstron; Andrew S. Jack; Allen Ebens
View on Scopus
Characterization of a nutrient feed precipitate from an E. coli fermentation process.
Biotechnology Progress, ISSN: 15206033
Lauren Speciner; Erin Mallon; Susan Leung; Mike Laird; Osigwe Esue
View on Scopus
RTM3, which controls long-distance movement of potyviruses, is a member of a new plant gene family encoding a meprin and TRAF homology domain-containing protein
Plant Physiology, ISSN: 15322548 00320889
Patrick Cosson; Luc Sofer; Quang Hien Le; Valérie Léger; Valérie Schurdi-Levraud; Steven A. Whitham; Miki L. Yamamoto; Suresh Gopalan; Olivier le Gall; Thierry Candresse; James C. Carrington; Frédéric Revers
View on Scopus
Noncompartmental kinetic analysis of DCE-MRI data from malignant tumors: Application to glioblastoma treated with bevacizumab
Magnetic Resonance in Medicine, ISSN: 15222594 07403194
Ruediger E. Port; Lisa J. Bernstein; Daniel P. Barboriak; Lu Xu; Timothy P.L. Roberts; Nicholas Van Bruggen
View on Scopus
Vascular endothelial growth factor and age-related macular degeneration: From basic science to therapy
Nature Medicine, ISSN: 1546170X 10788956
Napoleone Ferrara
View on Scopus
Molecular dynamics simulations of hydrotropic solubilization and self-aggregation of nicotinamide
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Yong Cui; Chenyue Xing; Yingqing Ran
View on Scopus
© 2025 Genentech, Inc. All rights reserved. This site is intended for US residents only.