Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 11001 - 11050 OF 15796 RESULTS

Efficacy and safety observed during 24 weeks of efalizumab therapy in patients with moderate to severe plaque psoriasis
Archives of Dermatology, ISSN: 0003987X
Alan Menter; Kenneth B. Gordon; Wayne Carey; Tiffani K. Hamilton; Scott Glazer; Ivor Caro; Nicole F. Li; Wayne P. Gulliver
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The changing role of thrombolytic therapy in the management of acute deep vein thrombosis
Therapy, ISSN: 14750708
Mahmood K Razavi; Charles P. Semba
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Are inflammatory cytokines the common link between cancer-associated cachexia and depression?
Journal of Supportive Oncology, ISSN: 15446794
James Illman; Robert Corringham; Don Robinson Jr.; Hugh M. Davis; Jean-Francois Rossi; Cella; Mohit Trikha
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Industry-based medical communications: Benchmarking survey of quality assurance practices
Drug Information Journal, ISSN: 00928615
S. Justin Hileman; Graham; Joyce Serrano Martin; Barry Grobman
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The anti-inflammatory effects of omalizumab confirm the central role of IgE in allergic inflammation
Journal of Allergy and Clinical Immunology, ISSN: 00916749
Stephen Holgate; Thomas B. Casale; Sally E. Wenzel; Jean Bousquet; Yamo Deniz; Colin Reisner
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Alteplase stability and bioactivity after low-power ultrasonic energy delivery with the OmniSonics resolution system
Journal of Vascular and Interventional Radiology, ISSN: 10510443
John Smikahl; Yeung; Sharon Wang; Charles P. Semba
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Alteplase as a catheter locking solution: In vitro evaluation of biochemical stability and antimicrobial properties
Journal of Vascular and Interventional Radiology, ISSN: 10510443
Weck; Samantha Cheung; Hiraoka-Sutow; Thomas W. Patapoff; Charles P. Semba
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Proteomic profiling of recombinant Escherichia coli in high-cell-density fermentations for improved production of an antibody fragment biopharmaceutical
Applied and Environmental Microbiology, ISSN: 00992240
Ilana S. Aldor; Denise C. Krawitz; William F. Forrest; Christina Y. Chen; Julie C. Nishihara; John C. Joly; Kathleen M. Champion
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Adjuvant and neoadjuvant therapy in non-small cell lung cancer
Seminars in Oncology, ISSN: 00937754
Chandra P. Belani
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Epidemiology of cystic fibrosis-related diabetes
Journal of Pediatrics, ISSN: 00223476
Marshall; Butler; Stoddard; Moran; Liou; Morgan; Seema Asthana
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Met activation and receptor dimerization in cancer: A role for the Sema domain
Cell Cycle, ISSN: 15514005 15384101
Dineli Wickramasinghe; Monica Kong-Beltran
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Depletion of B cells by a humanized anti-CD20 antibody PRO70769 in Macaca Fascicularis
Journal of Immunotherapy, ISSN: 15249557
Yulia Vugmeyster; Joseph Beyer; Howell; Dan Combs; Fielder; Yang; Ferhan Qureshi; Bryan Sandlund; Ly Kawaguchi; Wolfgang Dummer; Henry B. Lowman; Kathleen McKeever
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Maximum tolerated dose of a humanized anti-vascular endothelial growth factor antibody fragment for treating neovascular age-related macular degeneration
Ophthalmology, ISSN: 01616420
Philip J. Rosenfeld; Steven D. Schwartz; Mark S. Blumenkranz; Joan W. Miller; Julia A. Haller; Reimann; William L. Greene; Naveed Shams
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Uniform overexpression and rapid accessibility of α5β 1 integrin on blood vessels in tumors
American Journal of Pathology, ISSN: 00029440
Patricia Parsons-Wingerter; Ian Kasman; Scott Norberg; Anette Magnussen; Sara Zanivan; Alberto Rissone; Peter Baluk; Cecile J. Favre; Ursula Jeffry; Richard Murray; Donald M. McDonald
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A brief review of the use and utility of growth hormone stimulation testing in the NCGS: Do we need to do provocative GH testing?
Growth Hormone and IGF Research, ISSN: 15322238 10966374
Wilson; James W. Frane
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Single-molecule studies of synaptotagmin and complexin binding to the SNARE complex
Biophysical Journal, ISSN: 00063495
Mark E. Bowen; Keith Weninger; James A. Ernst; Steven Chu; Axel T. Brünger
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Development of a quantifiable symptom assessment tool for patients with chronic bronchitis: The Chronic Bronchitis Symptoms Assessment Scale
COPD: Journal of Chronic Obstructive Pulmonary Disease, ISSN: 15412563 15412555
David H. Au; David Blough; Leonard Kirchdoerfer; Kevin B.. Weiss; Edmunds M. Udris; Sean D. Sullivan
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Arming antibodies for cancer therapy
Current Opinion in Pharmacology, ISSN: 14714892
Paul G. Polakis
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Incidence of infection during efalizumab therapy for psoriasis: Analysis of the clinical trial experience
Clinical Therapeutics, ISSN: 1879114X 01492918
Richard G. B. Langley; Wayne Carey; Elyse S. Rafal; Stephen K. Tyring; Ivor Caro; Xiaolin Wang; Graham Wetherill; Kenneth B. Gordon
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PDA Technical Report No. 42: Process validation of protein manufacturing
PDA Journal of Pharmaceutical Science and Technology, ISSN: 10797440
Chris Bussineau; Robert Seely; Genevieve Lovitt; James Fernandez; Gregory S. Blank; Brandreth; Doris Conrad; Rebecca A. Devine; Robert J. Ferris; Koen De Heyder; Robert W. Juffras; Peter Levy; Wolfgang List; Morten Munk; Brian C. Neely; Stephen Notarnicola; O'Leary; Harold Van Deinse
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Good research practices for cost-effectiveness analysis alongside clinical trials: The ISPOR RCT-CEA Task Force report
Value in Health, ISSN: 10983015
Scott D. Ramsey; Richard Willke; Andrew Briggs; Ruth Brown; Martin Buxton; Chawla; John Cook; Henry Glick; Bengt Liljas; Diana Petitti; Shelby Reed
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Hormone receptor status does not affect the clinical benefit of trastuzumab therapy for patients with metastatic breast cancer
Clinical Breast Cancer, ISSN: 15268209
Adam Brufsky; Barry Lembersky; Kathy Schiffman; Lieberman; Virginia Paton
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Total serum IgE levels in a large cohort of patients with severe or difficult-to-treat asthma
Annals of Allergy, Asthma and Immunology, ISSN: 10811206
Larry Borish; Bradley E. Chipps; Yamo Deniz; Gujrathi; Zheng; Chantal M. Dolan
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Reversible self-association increases the viscosity of a concentrated monoclonal antibody in aqueous solution
Journal of Pharmaceutical Sciences, ISSN: 00223549
Jun Liu; Mary D. H. Nguyen; Andya; Steven J. Shire
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Capillary electrophoresis of carbohydrates derivatized with fluorophoric compounds.
Methods in Molecular Biology, ISSN: 10643745
Stacey Ma; Wendy Lau; Rodney Keck; Briggs; Andrew J.S. Jones; Kathy Moorhouse; Wassim Nashabeh
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Oligosaccharide release and MALDI-TOF MS analysis of N-linked carbohydrate structures from glycoproteins.
Methods in Molecular Biology, ISSN: 10643745
Rodney Keck; Briggs; Andrew J.S. Jones
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Regeneration of the adult central nervous system.
Current Biology, ISSN: 09609822
Lauren C Case; Marc Tessier-Lavigne
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Cancer risk in asthmatic populations
Annals of Allergy, Asthma and Immunology, ISSN: 10811206
Patricia Tennis; Beth Sherrill; Carlos Fernandez; Chantal M. Dolan
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Development and validation of the cystic fibrosis questionnaire in the United States: A health-related quality-of-life measure for cystic fibrosis
Chest, ISSN: 00123692
Alexandra L. Quittner; Anne Buu; Melissa A. Messer; Avani C. Modi; Marc Watrous
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Isolated central nervous system metastases in patients with HER2-overexpressing advanced breast cancer treated with first-line trastuzumab-based therapy
Annals of Oncology, ISSN: 15698041 09237534
Burstein; Lieberman; Dennis J. Slamon; Eric P. Winer; Pam Klein
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Vascular endothelial growth factor expression in the retinal pigment epithelium is essential for choriocapillaris development and visual function
American Journal of Pathology, ISSN: 00029440
Alexander G. Marneros; Jie Fan; Yoshihito Yokoyama; Hans-Peter Gerber; Napoleone Ferrara; Rosalie K. Crouch; Bjorn R. Olsen
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A role for Hath1, a bHLH transcription factor, in colon adenocarcinoma
Annals of the New York Academy of Sciences, ISSN: 00778923
Ching Ching Leow; Paul G. Polakis; Gao
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Influence of different hormonal regimens on endometrial microvascular density and VEGF expression in women suffering from breakthrough bleeding
Human Reproduction, ISSN: 14602350 02681161
Peter A.W. Rogers; Martinez; Girling; Lederman; Cann; Farrell; Tresserra; Patel
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Recombinant DNA Technology and Cell Line Development
Cell Culture Technology for Pharmaceutical and Cell-Based Therapies,
Amy Y. Shen; Jana Van de Goor; Lisa Zheng; Arthur Reyes; Lynne Krummen
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Activity-dependent internalization of smoothened mediated by β-Arrestin 2 and GRK2
Science, ISSN: 00368075
Wei Chen; Xiu-Rong Ren; Nelson; Larry S. Barak; James K. Chen; Philip A. Beachy; Frederic J. De Sauvage; Robert J. Lefkowitz
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Structural basis and therapeutic implication of the interaction of CCN proteins with glycoconjugates
Current Pharmaceutical Design, ISSN: 13816128
Luc Desnoyers
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Elimination of hepatic metastases of colon cancer cells via p53-independent cross-talk between irinotecan and Apo2 ligand/TRAIL
Cancer Research, ISSN: 00085472
Rajani Ravi; Ajay J. Jain; Richard D. Schulick; Vui Pham; Traci S. Prouser; Heather Allen; Elizabeth Garrett Mayer; Hua Yu; Drew M. Pardoll; Avi Ashkenazi; Atul Bedi
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Integrin α4β1 function is required for cell survival in developing retina
Developmental Biology, ISSN: 00121606
Sergiu T. Leu; Susan A.L. Jacques; Kevin L. Wingerd; Sherry T. Hikita; Erin C. Tolhurst; Jan L. Pring; Derek Wiswell; Lisa Kinney; Nichol L. Goodman; Jackson; Dennis O. Clegg
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IL-27 signaling compromises control of bacterial growth in mycobacteria-infected mice
Journal of Immunology, ISSN: 00221767
John E. Pearl; Shabaana A. Khader; Alejandra Solache; Leigh Gilmartin; Nico Ghilardi; Frederic J. De Sauvage; Andrea M. Cooper
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Roles of active site tryptophans in substrate binding and catalysis by α-1,3 galactosyltransferase
Glycobiology, ISSN: 09596658
Yingnan Zhang; Ashlesha Deshpande; Zhihong Xie; Ramanathan Natesh; K. Ravi Acharya; Keith Brew
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Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer
Journal of Clinical Oncology, ISSN: 0732183X
David H. Johnson; Louis Fehrenbacher; Novotny; Roy S. Herbst; John J. Nemunaitis; David M. Jablons; Corey Langer; Russell F. DeVore III; Jacques Gaudreault; Lisa A. Damico; Holmgren; Fairooz F. Kabbinavar
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Biological activity of bevacizumab, a humanized anti-VEGF antibody in vitro
Angiogenesis, ISSN: 09696970
Yaning Wang; David T.W. Fei; Vanderlaan; An Song
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Competency-based benchmarking: Revolutionizing biopharmaceutical product launches
Benchmarking, ISSN: 14635771
Mark J. Ahn; Daniel Dornbusch
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Endocytosis and sorting of ErbB2 and the site of action of cancer therapeutics trastuzumab and geldanamycin
Molecular Biology of the Cell, ISSN: 10591524
Cary D. Austin; Ann De Mazière; Paul Pisacane; Suzanne Van Dijk; Eigenbrot; Mark X. Sliwkowski; Judith Klumperman; Richard H. Scheller
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The endo-lysosomal sorting machinery interacts with the intermediate filament cytoskeleton
Molecular Biology of the Cell, ISSN: 10591524
Melanie L. Styers; Gloria Salazar; Rachal Love; Andrew A. Peden; Andrew P. Kowalczyk; Victor Faundez
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The burden of illness associated with psoriasis: Cost of treatment with systemic therapy and phototherapy in the US
Current Medical Research and Opinion, ISSN: 03007995
William H. Crown; Bresnahan; Lucinda S. Orsini; Sean Kennedy; Craig Leonardi
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Development of a PCR method for mycoplasma testing of Chinese hamster ovary cell cultures used in the manufacture of recombinant therapeutic proteins
Biologicals, ISSN: 10451056
Joyce A. Eldering; Chantal Felten; Connie A. Veilleux; Barbara J. Potts
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Safety of treatment of metastatic breast cancer with trastuzumab beyond disease progression
Journal of Clinical Oncology, ISSN: 0732183X
Debasish Tripathy; Dennis J. Slamon; Melody A. Cobleigh; Andrew Arnold; Mansoor Saleh; Joanne E. Mortimer; Maureen Murphy; Stanford J. Stewart
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Transcriptional-based screens for pathway-specific, high-throughput target discovery in endothelial cells
Journal of Biomolecular Screening, ISSN: 10870571
Robert Yauch; Edward E. Kadel III; Cory Nicholas; Selwyna Tetangco; Douglas O. Clary
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Effect of anti-TGF-Β antibodies in syngeneic mouse models of metastasis
Journal of Musculoskeletal Neuronal Interactions, ISSN: 11087161
Richard A. D. Carano; Li; Bao; Li; Berry; Ross; Joe Kowalski; French; Dugger; Ralph H. Schwall; Wang; David T.W. Fei; Sarah L. Moseley; Ellen H. Filvaroff
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