Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 11201 - 11250 OF 15583 RESULTS

March 18, 2003

The VIVA trial: Vascular endothelial growth factor in ischemia for vascular angiogenesis

Circulation, ISSN: 00097322

Timothy D. Henry; Brian H. Annex; George McKendall; Michael A. Azrin; John J. Lopez; Frank J. Giordano; Shah; James T. Willerson; Raymond L. Benza; Daniel S. Berman; C.Michael Gibson; Alex Bajamonde; Amy Chen Rundle; Jennifer T. Fine; Edward R. McCluskey

March 17, 2003

Type-I interferon receptor deficiency reduces lupus-like disease in NZB mice

Journal of Experimental Medicine, ISSN: 00221007

Marie-Laure Santiago-Raber; Roberto Baccala; Katarina M. Haraldsson; Divaker Choubey; Stewart; Dwight H. Kono; Argyrios N. Theofilopoulos

March 15, 2003

Nucleic acid capture assay, a new method for direct quantitation of nucleic acids

Nucleic Acids Research, ISSN: 13624962

Siao Ping Tsai; Anne Wong; Elaine Mai; Pamela Chan; Grace Mausisa; Vasser; Jhurani; Mogens H. Jakobsen; Wai Lee T. Wong; Jean-Philippe Stephan

March 7, 2003

HIF-1α is essential for myeloid cell-mediated inflammation

Cell, ISSN: 00928674

Thorsten Cramer; Yuji Yamanishi; Björn E. Clausen; Irmgard Förster; Rafal Pawlinski; Nigel Mackman; Volker H. Haase; Rudolf Jaenisch; Maripat Corr; Victor Nizet; Gary S. Firestein; Hans-Peter Gerber; Napoleone Ferrara; Randall S. Johnson

March 4, 2003

The endocrine-gland-derived VEGF homologue Bv8 promotes angiogenesis in the testis: Localization of Bv8 receptors to endothelial cells

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Jennifer Lecouter; Rui Lin; Max L. Tejada; Gretchen D. Frantz; Franklin V. Peale Jr.; Kenneth J. Hillan; Napoleone Ferrara

March 1, 2003

Selective cyclin-dependent kinase 2/cyclin A antagonists that differ from ATP site inhibitors block tumor growth

Cancer Research, ISSN: 00085472

Nerissa Mendoza; Fong; James C. Marsters Jr.; Koeppen; Ralph H. Schwall; Dineli Wickramasinghe

March 1, 2003

α-1-acid glycoprotein as an independent predictor for treatment effects and a prognostic factor of survival in patients with non-small cell lung cancer treated with docetaxel

Clinical Cancer Research, ISSN: 10780432

Rene Bruno; Robert Olivares; Jocelyne Berille; Philip Chaikin; Nicole Vivier; Luz Hammershaimb; Gerald R. Rhodes; James R. Rigas

March 1, 2003

Intravenous mouse infection model for studying the pathology of Enterococcus faecalis infections

Infection and Immunity, ISSN: 00199567

Claudia Gentry-Weeks; Monica Estay; Cindy Loui; Dale Baker

March 1, 2003

A randomized controlled trial evaluating the efficacy and safety of intermittent 3-, 4-, and 5-day cycles of intravenous recombinant human interleukin-2 combined with antiretroviral therapy (ART) versus ART alone in HIV-seropositive patients with 100-300 CD4+ T cells

Clinical Immunology, ISSN: 15216616

Alberdina W. De Boer; Norman Markowitz; H.Clifford Lane; Louis D. Saravolatz; Susan L. Koletar; Haig Donabedian; Carl Yoshizawa; A-M. Duliege; Gwendolyn Fyfe; Ronald T. Mitsuyasu

March 1, 2003

A crucial role of CD4 T cells as a functional source of CD154 in the initiation of insulin-dependent diabetes mellitus in the non-obese diabetic mouse

International Immunology, ISSN: 09538178

Koji Eshima; Conchi Mora; F. Susan Wong; E. Allison Green; Iqbal S. Grewal; Richard A. Flavell

February 28, 2003

Origins of PDZ domain ligand specificity. Structure determination and mutagenesis of the erbin PDZ domain

Journal of Biological Chemistry, ISSN: 00219258

Nicholas J. Skelton; Michael F. T. Koehler; Zobel; Wai Lee T. Wong; Sherry Yeh; Pisabarro; Jianping Yin; Lasky; Sachdev S. Sidhu

February 15, 2003

Inhibition of human papilloma virus E2 DNA binding protein by covalently linked polyamides

Nucleic Acids Research, ISSN: 03051048

Thomas D. Schaal; William Mallet; Dustin McMinn; Nam V. Nguyen; Michelle M. Sopko; Sam John; Bhavin S. Parekh

February 15, 2003

High-throughput protein sequencing

Analytical Chemistry, ISSN: 00032700

Victoria Pham; Jake Tropea; Suzy Wong; James Quach; William J. Henzel

February 7, 2003

Angiogenesis-independent endothelial protection of liver: Role of VEGFR-1

Science, ISSN: 00368075

Jennifer Lecouter; Dirk R. Moritz; Bing Li; Gail L. Phillips; Xiao Huan Liang; Hans-Peter Gerber; Kenneth J. Hillan; Napoleone Ferrara

February 6, 2003

Mutations in the exocyst component Sec5 disrupt neuronal membrane traffic, but neurotransmitter release persists

Neuron, ISSN: 08966273

Mala Murthy; Dan Garza; Richard H. Scheller; Thomas L. Schwarz

February 1, 2003

Turn stability in β-hairpin peptides: Investigation of peptides containing 3:5 type I G1 bulge turns

Protein Science, ISSN: 09618368

Tamas Blandl; Andrea G Cochran; Nicholas J. Skelton

February 1, 2003

Isolating Substrates for an Engineered α-Lytic Protease by Phage Display

Journal of Protein Chemistry, ISSN: 02778033

Samantha Lien; Geoffrey L. Francis; Lloyd D. Graham; John C. Wallace

February 1, 2003

Early treatment with hepatocyte growth factor improves cardiac function in experimental heart failure induced by myocardial infarction

Journal of Pharmacology and Experimental Therapeutics, ISSN: 00223565

Hongkui Jin; Renhui Yang; Wei Li; Annie Ogasawara; Ralph H. Schwall; Eberhard; Zhong Zheng; David W. Kahn; Nicholas F. Paoni

February 1, 2003

Loss of TACI causes fatal lymphoproliferation and autoimmunity, establishing TACI as an inhibitory BLyS receptor

Immunity, ISSN: 10747613

Dhaya Seshasayee; Patricia A. Valdez; Minhong Yan; Vishva M. Dixit; Daniel B. Tumas; Iqbal S. Grewal

February 1, 2003

Do growth hormone (GH) serial sampling, insulin-like growth factor-I (IGF-I) or auxological measurements have an advantage over GH stimulation testing in predicting the linear growth response to GH therapy?

Clinical Endocrinology, ISSN: 03000664

Alan D. Rogol; Sandra L. Blethen; Judy P. Sy; Johannes D. Veldhuis

February 1, 2003

Impairment of myocardial perfusion in both culprit and nonculprit arteries in acute myocardial infarction: A LIMIT AMI substudy

American Journal of Cardiology, ISSN: 00029149

Sabina A. Murphy; Christopher Chen; Steven G. Gourlay; Raymond J. Gibbons; Hal V. Barron; C.Michael Gibson

February 1, 2003

A unified model for apical caspase activation

Molecular Cell, ISSN: 10972765

Kelly M. Boatright; Martin Renatus; Fiona L. Scott; Sabina Sperandio; Hwain Shin; Irene M. Pedersen; Jean-Ehrland Ricci; Wade A. Edris; Daniel P. Sutherlin; Douglas R. Green; Guy S. Salvesen

February 1, 2003

Adhesion molecules as therapeutic targets for autoimmune diseases and transplant rejection

Expert Opinion on Biological Therapy, ISSN: 14712598

Russell L Dedrick; Bodary; Marvin Garovoy

February 1, 2003

Differential scanning calorimetric, circular dichroism, and Fourier transform infrared spectroscopic characterization of the thermal unfolding of xylanase A from Streptomyces lividans

Proteins: Structure, Function and Bioinformatics, ISSN: 08873585

Roberge; Ruthven N.A.H. Lewis; François Shareck; Rolf Morosoli; Dieter Kluepfel; Claude Dupont; Ronald N. McElhaney

February 1, 2003

A profile hidden Markov model for signal peptides generated by HMMER

Bioinformatics, ISSN: 13674803

Zemin Zhang; William I. Wood

January 29, 2003

UV Raman spectrum of 1,3-dimethylcyclopentenyl cation adsorbed in zeolite H-MFI

Journal of the American Chemical Society, ISSN: 00027863

Yek Tann Chua; Peter C. Stair; John B. Nicholas; Weiguo Song; James F. Haw

January 28, 2003

Distribution of toll-like receptor 1 and toll-like receptor 2 in human lymphoid tissue

Immunology, ISSN: 00192805

Maria Teresa Ochoa; Annaliza Legaspi; Zena Hatziris; Godowski; Robert L. Modlin; Peter A. Sieling

January 23, 2003

Activation of human CD4+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype

Nature, ISSN: 00280836

Claudia Kemper; Andrew A. Chan; Jonathan M. Green; Kelly A. Brett; Kenneth M. Murphy; John P. Atkinson

January 17, 2003

Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17

Journal of Biological Chemistry, ISSN: 00219258

Aggarwal; Nico Ghilardi; Xie; Frederic J. De Sauvage; Austin L. Gurney

January 15, 2003

Stability of cyclic β-hairpins: Asymmetric contributions from side chains of a hydrogen-bonded cross-strand residue pair

Journal of the American Chemical Society, ISSN: 00027863

Russell; Tamas Blandl; Nicholas J. Skelton; Andrea G Cochran

January 3, 2003

Exploring protein-protein interactions with phage display

ChemBioChem, ISSN: 14394227

Sachdev S. Sidhu; Wayne J. Fairbrother; Deshayes

January 1, 2003

Seminars in Oncology Nursing: Introduction

Seminars in Oncology Nursing, ISSN: 07492081

Kristi V. Schmidt

January 1, 2003

Phase i I, randomized trial comparing bevacizumab plus fluorouracil (FU)/Leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer

Journal of Clinical Oncology, ISSN: 15277755 0732183X

Fairooz F. Kabbinavar; Herbert Hurwitz; Louis Fehrenbacher; Neal J. Meropol; Novotny; Lieberman; Susan Griffing; Emily Bergsland

January 1, 2003

Branching out: A molecular fingerprint of endothelial differentiation into tube-like structures generated by affymetrix oligonucleotide arrays

Microcirculation, ISSN: 10739688

Mary E. Gerritsen; Robert Soriano; Suya Yang; Constance Zlot; Gladys S. Ingle; Toy; P. Mickey Williams

January 1, 2003

Therapeutic peptides

Trends in Biotechnology, ISSN: 01677799

Samantha Lien; Henry B. Lowman

January 1, 2003

Immunofluorescent labeling of cancer marker Her2 and other cellular targets with semiconductor quantum dots

Nature Biotechnology, ISSN: 10870156

Xingyong Wu; Hongjian Liu; Jianquan Liu; Kari N. Haley; Joseph A. Treadway; J. Peter Larson; Nianfeng Ge; Franklin V. Peale Jr.; Marcel P. Bruchez

January 1, 2003

Small molecule antagonists of proteins

Biochemical Pharmacology, ISSN: 00062952

Thomas Gadek; John B. Nicholas

January 1, 2003

Guidelines for the diagnosis and therapy of adult myelodysplastic syndromes

British Journal of Haematology, ISSN: 00071048

David Bowen; Dominic Culligan; Simon Jowitt; Stephen Kelsey; Ghulam Mufti; David Oscier; Jane Parker

January 1, 2003

Foreword

Microcirculation, ISSN: 10739688

Mary E. Gerritsen

January 1, 2003

NMR structural analysis of vascular endothelial growth factor in complex with a phage-derived peptide antagonist

Spectroscopy, ISSN: 07124813

Borlan Pan; Wayne J. Fairbrother

January 1, 2003

Apo2L/TRAIL and its death and decoy receptors

Cell Death and Differentiation, ISSN: 13509047

Heidi LeBlanc; Avi Ashkenazi

January 1, 2003

Zinc finger protein too few controls the development of monoaminergic neurons

Nature Neuroscience, ISSN: 10976256

Gil Levkowitz; Jörg Zeller; Howard I. Sirotkin; French; Sarah Schilbach; Hisashi Hashimoto; Masahiko Hibi; William S. Talbot; Rosenthal

January 1, 2003

β-hairpin polypeptides by design and selection

Spectroscopy, ISSN: 07124813

Nicholas J. Skelton; Tamas Blandl; Russell; Melissa A. Starovasnik; Andrea G Cochran

January 1, 2003

VEGF-C mediates cyclic pressure-induced endothelial cell proliferation

Physiological Genomics, ISSN: 15312267

Hainsworth Y. Shin; Michael L. Smith; Toy; P. Mickey Williams; Rena Bizios; Mary E. Gerritsen

January 1, 2003

Targeting VEGF ligands and receptors in cancer

Drug Discovery Today: TARGETS, ISSN: 17418372

Ajay K. Malik; Hans-Peter Gerber

January 1, 2003

The role of VEGF in normal and neoplastic hematopoiesis

Journal of Molecular Medicine, ISSN: 09462716

Hans-Peter Gerber; Napoleone Ferrara

January 1, 2003

Time course of skeletal muscle repair and gene expression following acute hind limb ischemia in mice

Physiological Genomics, ISSN: 15312267

Nicholas F. Paoni; Franklin V. Peale Jr.; Fay Wang; Errett-Baroncini; Hope Steinmetz; Toy; Wei Bai; P. Mickey Williams; Bunting; Mary E. Gerritsen; Powell-Braxton

January 1, 2003

The best of both worlds?: Potential of hybrid prospective/concurrent risk adjustment

Medical Care, ISSN: 00257079

R. Adams Dudley; Carol A. Medlin; Lisa B. Hammann; Miriam G. Cisternas; Richard Brand; Deborah J. Rennie; Harold S. Luft

January 1, 2003

Neutralization of Western diet inhibits bone resorption independently of K intake and reduces cortisol secretion in humans

American Journal of Physiology - Renal Physiology, ISSN: 03636127

Marc Maurer; Walter Riesen; Juergen Muser; Henry N. Hulter; Reto Krapf

January 1, 2003

Omalizumab, a recombinant humanized anti-IgE antibody, reduces asthma-related emergency room visits and hospitalizations in patients with allergic asthma

Journal of Allergy and Clinical Immunology, ISSN: 00916749

Jonathan Corren; Thomas B. Casale; Yamo Deniz; Ashby

Join Our Team

The little things we do every day add up to big breakthroughs. Making a difference in the lives of millions starts when you make a change in yours.

Two Scientists Walk Into a Bar

Two Scientists Walk Into a Bar

Listen to our podcast, where researchers talk about their work answering the toughest questions in human biology.