Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 11601 - 11650 OF 15796 RESULTS

AKT/PKB phosphorylation of p21Cip/WAF1 enhances protein stability of p21Cip/WAF1 and promotes cell survival
Journal of Biological Chemistry, ISSN: 00219258
Ying Li; Dowbenko; Lasky
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Inhibitors of protein-protein interactions
Expert Opinion on Therapeutic Patents, ISSN: 13543776
Denise A. Ockey; Thomas Gadek
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A human antibody that inhibits factor IX/IXa function potently inhibits arterial thrombosis without increasing bleeding
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN: 10795642
Refino; Surinc Er Jeet; Leo Deguzman; Bunting; Daniel Kirchhofer
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Identification of a novel homotypic interaction motif required for the phosphorylation of receptor-interacting protein (RIP) by RIP3
Journal of Biological Chemistry, ISSN: 00219258
Xiaoqing Sun; Jianping Yin; Melissa A. Starovasnik; Wayne J. Fairbrother; Vishva M. Dixit
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Characterization of endocrine gland-derived vascular endothelial growth factor signaling in adrenal cortex capillary endothelial cells
Journal of Biological Chemistry, ISSN: 00219258
Rui Lin; Jennifer Lecouter; Joe Kowalski; Napoleone Ferrara
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Methylbenzene chemistry on zeolite HBeta: Multiple insights into methanol-to-olefin catalysis
Journal of Physical Chemistry B, ISSN: 10895647
Alain Sassi; Mark A. Wildman; Hee Jung Ahn; Paritosh Prasad; John B. Nicholas; James F. Haw
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1H, 13C, and 15N resonance assignment of the vascular endothelial growth factor receptor-binding domain in complex with a receptor-blocking peptide [5]
Journal of Biomolecular NMR, ISSN: 09252738
Borlan Pan; Wayne J. Fairbrother
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Expression profiling of a human cell line model of prostatic cancer reveals a direct involvement of interferon signaling in prostate tumor progression
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Shou; Robert Soriano; Simon W. Hayward; Gerald R. Cunha; P. Mickey Williams; Gao
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Chemometric evaluation of on-line high-pressure liquid chromatography in mammalian cell cultures: Analysis of amino acids and glucose
Biotechnology and Bioengineering, ISSN: 00063592
Tina M. Larson; Martin Gawlitzek; Heather Evans; Urs Albers; Cacia
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Microcirculation down under
Trends in Pharmacological Sciences, ISSN: 01656147
Tailoi Chan-Ling; Mary E. Gerritsen; Caryl E Hill; Paul Kubes; Michael Perry
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Cardiac dysfunction in the trastuzumab clinical trials experience
Journal of Clinical Oncology, ISSN: 0732183X
Andrew Seidman; Clifford Hudis; Mary Kathryn Pierri; Steven Shak; Virginia Paton; Ashby; Maureen Murphy; Stanford J. Stewart; Deborah Keefe
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Activation of the Wnt pathway interferes with serum response element-driven transcription of immediate early genes
Journal of Biological Chemistry, ISSN: 00219258
David A. Tice; Soloviev; Paul G. Polakis
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Bacterial toxins as tools for mucosal vaccination
Drug Discovery Today, ISSN: 13596446
Mrsny; Daugherty; Marian McKee; David FitzGerald
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Vascular endothelial-junctional adhesion molecule (VE-JAM)/JAM 2 interacts with T, NK, and dendritic cells through JAM 3
Journal of Immunology, ISSN: 00221767
Tony W. Liang; Chiu; Austin L. Gurney; Aiko Sidle; Daniel B. Tumas; Peter Schow; Foster; Toni Klassen; Kathryn Dennis; Richard A. Demarco; Thinh Q. Pham; Gretchen D. Frantz; Sherman Fong
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The core membrane fusion complex governs the probability of synaptic vesicle fusion but not transmitter release kinetics
Journal of Neuroscience, ISSN: 02706474
Finley; Sejal M. Patel; Daniel V. Madison; Richard H. Scheller
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Vascular endothelial-junctional adhesion molecule (VE-JAM)/JAM 2 interacts with T, NK, and dendritic cells through JAM 3
Journal of Immunology, ISSN: 00221767
Tony W. Liang; Chiu; Austin L. Gurney; Aiko Sidle; Daniel B. Tumas; Peter Schow; Foster; Toni Klassen; Kathryn Dennis; Richard A. Demarco; Thinh Q. Pham; Gretchen D. Frantz; Fong
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Cold elicits the simultaneous induction of fatty acid synthesis and β-oxidation in murine brown adipose tissue: Prediction from differential gene expression and confirmation in vivo
FASEB Journal, ISSN: 08926638
Xing Xian; Lewin; William F. Forrest; Adams
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Generation of an LFA-1 antagonist by the transfer of the ICAM-1 immunoregulatory epitope to a small molecule
Science, ISSN: 00368075
Thomas Gadek; Burdick; Robert S. McDowell; Mark S. Stanley; James C. Marsters Jr.; Kenneth J. Paris; David A. Oare; Mark E. Reynolds; Ladner; Kimberly Zioncheck; Wyne P. Lee; Gribling; Dennis; Nicholas J. Skelton; Daniel B. Tumas; Clark; Keating; Beresini; Tilley; Presta; Bodary
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Nitrogen assimilation and growth of wheat under elevated carbon dioxide
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Arnold J. Bloom; David R. Smart; Duy T. Nguyen; Peter S. Searles
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Surface-tension-confined microfluidics
Langmuir, ISSN: 07437463
Philippe Lam; Kenneth J. Wynne; Gary E. Wnek
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Stable "zeta" peptides that act as potent antagonists of the high-affinity IgE receptor
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Nakamura; Mark E. Reynolds; Chen; Melissa A. Starovasnik; Henry B. Lowman
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Host defense functions of proteolytically processed and parent (unprocessed) cathelicidins of rabbit granulocytes
Infection and Immunity, ISSN: 00199567
Kol A. Zarember; Seth S. Katz; Brian F. Tack; Laurence Doukhan; Weiss; Elsbach
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PSTPIP is a substrate of PTP-PEST and serves as a scaffold guiding PTP-PEST toward a specific dephosphorylation of WASP
Journal of Biological Chemistry, ISSN: 00219258
Jean-François Côté; Ping Lin Chung; Jean-François Théberge; Maxime Hallé; Spencer; Lasky; Michel L. Tremblay
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IL-17: Prototype member of an emerging cytokine family
Journal of Leukocyte Biology, ISSN: 07415400
Aggarwal; Austin L. Gurney
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New insight into how tissue factor allosterically regulates Factor VIIa
Trends in Cardiovascular Medicine, ISSN: 10501738
Eigenbrot; Daniel Kirchhofer
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Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines
Journal of Immunology, ISSN: 00221767
Kol A. Zarember; Godowski
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Photodetachment and theoretical study of free and water-solvated nitrate anions, NO3-(H2O)n (n=0-6)
Journal of Chemical Physics, ISSN: 00219606
Xue-Bin Wang; Xin Yang; Lai-Sheng Wang; John B. Nicholas
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MRI measurement of cerebral water diffusion and its application to experimental research
Biomedical Imaging in Experimental Neuroscience,
Richard A. D. Carano; Nicholas Van Bruggen; De Crespigny
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Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth
Cancer Cell, ISSN: 15356108
David B. Agus; Robert W. Akita; Fox; Gail D. Lewis; Higgins; Paul Pisacane; Julie A. Lofgren; Charles Tindell; Douglas P. Evans; Maiese; Scher; Mark X. Sliwkowski
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Inconsistencies in reporting the occurrence and timing of first intercourse among adolescents
Journal of Sex Research, ISSN: 00224499
Dawn M. Upchurch; Lee A. Lillard; Carol S. Aneshensel; Nicole F. Li
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Phase I study of the combination of losoxantrone and cyclophosphamide in patients with refractory solid tumours
British Journal of Cancer, ISSN: 00070920
Goh; Vokes; Amita Joshi; Ratain
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Rituximab: Ongoing and future clinical development
Seminars in Oncology, ISSN: 00937754
Grillo-Lopez; Eric Hedrick; Michelle Rashford; Benyunes
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Gene expression profiling in silico: Relative expression of candidate angiogenesis associated genes in renal cell carcinomas
Experimental Nephrology, ISSN: 10187782
Mary E. Gerritsen; Franklin V. Peale Jr.; Thomas D Wu
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Rantes, a monocyte and T lymphocyte chemotactic cytokine releases histamine from human basophils
Journal of Immunology, ISSN: 00221767
Piotr Kuna; Sesha R. Reddigari; Thomas J. Schall; Doreen Rucinski; Michael Y. Viksman; Allen P. Kaplan
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A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease
Gastroenterology, ISSN: 00165085
Yevgeny Zolotarevsky; Athanasia Koutsouris; Deborah E. Gonzalez; Quan; Jeffrey Tom; Mrsny; Jerrold R. Turner
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Evaluation of total IGF-I assay methods using samples from Type I and Type II diabetic patients
Journal of Immunological Methods, ISSN: 00221759
Chestnut; Quarmby
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Oncogenic human papillomavirus E6 proteins target the MAGI-2 and MAGI-3 proteins for degradation
Oncogene, ISSN: 09509232
Miranda Thomas; Richard Laura; Karin Hepner; Ernesto Guccione; Charles L. Sawyers; Lasky; Lawrence Banks
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Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth
Cancer Cell, ISSN: 15356108
Agus; Robert W. Akita; Fox; Gail D. Lewis; Higgins; Paul Pisacane; Julie A. Lofgren; Charles Tindell; Douglas P. Evans; Maiese; Scher; Mark X. Sliwkowski
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In silico data filtering to identify new angiogenesis targets from a large in vitro gene profiling data set
Physiological Genomics, ISSN: 15312267
Mary E. Gerritsen; Robert Soriano; Suya Yang; Gladys S. Ingle; Constance Zlot; Toy; Jane Winer; Aparna Draksharapu; Franklin V. Peale Jr.; Thomas D Wu; P. Mickey Williams
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Tumor-cell resistance to death receptor-induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax
Nature Medicine, ISSN: 10788956
Heidi LeBlanc; David Lawrence; Eugene Varfolomeev; Klara Totpal; John Morlan; Peter Schow; Fong; Ralph H. Schwall; Sinicropi; Avi Ashkenazi
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Safety and efficacy of alteplase for restoring function in occluded central venous catheters: Results of the cardiovascular thrombolytic to open occluded lines trial
Journal of Clinical Oncology, ISSN: 0732183X
Steven R. Deitcher; Mark R Fesen; Paul M Kiproff; Hill; Xin Li; Edward R. McCluskey; Charles P. Semba
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EG-VEGF and the concept of tissue-specific angiogenic growth factors
Seminars in Cell and Developmental Biology, ISSN: 10849521
Jennifer Lecouter; Napoleone Ferrara
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Production information management
Pharmaceutical Technology, ISSN: 01478087
Hans Koning-Bastiaan
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Validation of large-scale chromatographic processes, Part 1: Case study of neuleze capture on Macroprep High-S
BioPharm, ISSN: 10408304
Timothy N. Breece; Ellen Gilkerson; Charles H. Schmelzer
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Enhancing the anticoagulant potency of soluble tissue factor mutants by increasing their affinity to factor VIIa
Thrombosis and Haemostasis, ISSN: 03406245
Yang; Geoffrey F. Lee; Markus A. Riederer; Robert F. Kelley
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The importance of freezing on lyophilization cycle development
BioPharm, ISSN: 10408304
Thomas W. Patapoff; David E. Overcashier
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Hippocampal dysfunction and behavioral deficit in the water maze in mice: An unresolved issue?
Brain Research Bulletin, ISSN: 03619230
Gerlai; Alexander McNamara; Simon P. Williams; Phillips
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A real-time quantitative PCR-based method for the detection and quantification of xenotropic Murine Leukemia Virus (X-MuLV) and its application in evaluation of X-MuLV removal during pharmaceutical protein purification
Process in Safety Science and Technology Part B,
Shi; Qi Chen; Lenore A Norling; Allen S.L. Lau; Sherrie Krejci; Yuan Xu
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Evaluation of a quantitative product-enhanced reverse transcriptase assay to monitor retrovirus in mAb cell-culture
Biologicals, ISSN: 10451056
Kurt Brorson; Yuan Xu; Patrick Swann; Elizabeth Hamilton; Mehnaz Mustafa; Christina De Wit; Lenore A Norling; Kathryn Stein
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Selective detection of membrane proteins without antibodies: a mass spectrometric version of the Western blot.
Molecular and Cellular Proteomics, ISSN: 15359476
David Arnott; Kishiyama; Luis; Sarah Ludlum; James C. Marsters Jr.; Stults
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