Genentech: Publications

March 17, 2000

TrkA amino acids controlling specificity for nerve growth factor

Journal of Biological Chemistry, ISSN: 00219258

O'Connell; Hongo; Presta; Tsoulfas

March 17, 2000

Highly organized spherical hosts that bind organic guests in aqueous solution with micromolar affinity: Microcalorimetry studies

Chemistry - A European Journal, ISSN: 09476539

Evgueni L. Piatnitski; Robert A. Flowers II; Deshayes

View on Scopus

March 14, 2000

A phase II trial of nerve growth factor for sensory neuropathy associated with HIV infection

Neurology, ISSN: 00283878

McArthur; Yiannoutsos; Simpson; Bruce T. Adornato; Singer; Hollander; Marra; Rubin; Cohen; Tucker; Navia; Schifitto; Katzenstein; Rask; Zaborski; Smith; Shriver; Millar; Clifford

View on Scopus

March 13, 2000

Treatment and outcome of myocardial infarction in hospitals with and without invasive capability

Journal of the American College of Cardiology, ISSN: 07351097

William J. Rogers; John G. Canto; Hal V. Barron; Joseph A Boscarino; David A. Shoultz; Nathan R. Every

View on Scopus

March 13, 2000

Spinal motor axons and neural crest cells use different molecular guides for segmental migration through the rostral half-somite

Journal of Neurobiology, ISSN: 00223034

Koblar; Krull; Pasquale; McLennan; Peale; Cerretti; Bothwell

View on Scopus

March 10, 2000

Macromolecular inhibitors of HIV-1 protease. Characterization of designed heterodimers

Journal of Biological Chemistry, ISSN: 00219258

James E. Rozzelle; Deborah S. Dauber; Stephen Todd; Robert F. Kelley; Charles S. Craik

View on Scopus

March 7, 2000

Recombinant human thrombopoietin attenuates carboplatin-induced severe thrombocytopenia and the need for platelet transfusions in patients with gynecologic cancer

Annals of Internal Medicine, ISSN: 00034819

Saroj Vadhan-Raj; Claire F. Verschraegen; Carlos Bueso-Ramos; Hal E. Broxmeyer; Andrzej P. Kudelka; Ralph S. Freedman; Creighton L. Edwards; David Gershenson; Jones Jr.; Ashby; John J. Kavanagh

View on Scopus

March 3, 2000

Wnt signaling in oncogenesis and embryogenesis - A look outside the nucleus

Science, ISSN: 00368075

Mark Peifer; Paul G. Polakis

View on Scopus

March 2, 2000

Toll genes and responsiveness to bacterial endotoxins [7] (multiple letters)

New England Journal of Medicine, ISSN: 00284793

James A. Thomas; Robert L. Modlin; Hans D. Brightbill; Godowski

View on Scopus

March 1, 2000

Structure of the highly conserved HERC2 gene and of multiple partially duplicated paralogs in human

Genome Research, ISSN: 10889051

Yonggang Ji; Nancy A. Rebert; John M. Joslin; Michael J. Higgins; Roger A. Schultz; Robert D. Nicholls

View on Scopus

March 1, 2000

Anesthesia induced retrograde amnesia is ameliorated by ephrin A5-IgG in mice: EphA receptor tyrosine kinases are involved in mammalian memory

Behavioural Brain Research, ISSN: 01664328

Gerlai; Alexander McNamara

View on Scopus

March 1, 2000

International union of pharmacology. XXII. Nomenclature for chemokine receptors

Pharmacological Reviews, ISSN: 00316997

Philip M. Murphy; Marco Baggiolini; Israel F. Charo; Hébert; Richard Horuk; Kouji Matsushima; Miller; Joost J. Oppenheim; Christine A. Power

View on Scopus

March 1, 2000

WISP-1 is a Wnt-1- and β-catenin-responsive oncogene

Genes and Development, ISSN: 08909369

Lifeng Xu; Ryan B. Corcoran; James W. Welsh; Diane Pennica; Arnold J. Levine

View on Scopus

March 1, 2000

Do nerve growth factor-related mechanisms contribute to loss of cutaneous nociception in leprosy?

Pain, ISSN: 03043959

Paul Facer; Dawn Mann; Rajeev Mathur; Shubha Pandya; Uma Ladiwala; Bhim Singhal; Hongo; Sinicropi; Giorgio Terenghi; Anand

View on Scopus

March 1, 2000

Receptor-binding conformation of the 'ELR' motif of IL-8: X-ray structure of the L5C/H33C variant at 2.35 Å resolution

Proteins: Structure, Function and Bioinformatics, ISSN: 08873585

Nancy Gerber; Henry B. Lowman; Dean R. Artis; Eigenbrot

View on Scopus

February 21, 2000

Oncogenic Raf-1 disrupts epithelial tight junctions via downregulation of occludin

Journal of Cell Biology, ISSN: 00219525

Danxi Li; Mrsny

View on Scopus

February 20, 2000

Comparison of three treatment options for single brain metastasis from lung cancer

International Journal of Cancer, ISSN: 00207136

Jun Itakura; Toshiyuki Ishiwata; Shen; Marko Kornmann; Murray Korc

View on Scopus

February 18, 2000

Convergent solutions to binding at a protein-protein interface

Science, ISSN: 00368075

Warren L. DeLano; Ultsch; De Vos; James A. Wells

View on Scopus

February 18, 2000

High copy display of large proteins on phage for functional selections

Journal of Molecular Biology, ISSN: 00222836

Sachdev S. Sidhu; Gregory A. Weiss; James A. Wells

View on Scopus

February 15, 2000

Increased death receptor 5 expression by chemotherapeutic agents in human gliomas causes synergistic cytotoxicity with tumor necrosis factor- related apoptosis-inducing ligand in vitro and in vivo

Cancer Research, ISSN: 00085472

Motoo Nagane; Pan; Jessie J. Weddle; Vishva M. Dixit; Cavenee; Su Huang

View on Scopus

February 9, 2000

Assessment of the myotoxicity of pharmaceutical buffers using an in vitro muscle model: Effect of pH, capacity, tonicity, and buffer type

Pharmaceutical Development and Technology, ISSN: 10837450

Jintana Napaporn; Maike Thomas; Kari A. Svetic; Shahrokh; Gayle A. Brazeau

View on Scopus

February 7, 2000

Src-like adaptor protein (SLAP) is a negative regulator of T cell receptor signaling

Journal of Experimental Medicine, ISSN: 00221007

Tomasz Sosinowski; Akhilesh Pandey; Vishva M. Dixit; Arthur Weiss

View on Scopus

February 4, 2000

Simian virus 40 large T antigen binds a novel Bcl-2 homology domain 3- containing proapoptosis protein in the cytoplasm

Journal of Biological Chemistry, ISSN: 00219258

Shih-Chong Tsai; Kishore B. S. Pasumarthi; Laura Pajak; Michael Franklin; Brian Patton; He Wang; William J. Henzel; Stults; Loren J. Field

View on Scopus

February 1, 2000

Long-term survival update for high-dose recombinant interleukin-2 in patients with renal cell carcinoma

Cancer Journal from Scientific American, ISSN: 10814442

Richard I. Fisher; Steven A. Rosenberg; Gwendolyn Fyfe

View on Scopus

February 1, 2000

Transient focal cerebral ischemia induces sensorimotor deficits in mice

Behavioural Brain Research, ISSN: 01664328

Gerlai; Harold Thibodeaux; James T. Palmer; Menno Van Lookeren Campagne; Nicholas Van Bruggen

View on Scopus

February 1, 2000

Isolation and characterization of CRF-related diuretic hormones from the whitelined sphinx moth Hyles lineata

Insect Biochemistry and Molecular Biology, ISSN: 09651748

Kenji Furuya; Marilyn A. Harper; Kathleen M. Schegg; David A. Schooley

View on Scopus

February 1, 2000

High-dose recombinant interleukin-2 therapy in patients with metastatic melanoma: Long-term survival update

Cancer Journal from Scientific American, ISSN: 10814442

Michael B. Atkins; Lori Kunkel; Mario Sznol; Steven A. Rosenberg

View on Scopus

February 1, 2000

Intracranial hemorrhage rates and effect of immediate beta-blocker use in patients with acute myocardial infarction treated with tissue plasminogen activator

American Journal of Cardiology, ISSN: 00029149

Hal V. Barron; Amy Chen Rundle; Joel M. Gore; Jerry H. Gurwitz; Jan Penney

View on Scopus

January 29, 2000

Brain-derived neurotrophic factor induces excitotoxic sensitivity in cultured embryonic rat spinal motor neurons through activation of the phosphatidylinositol 3-kinase pathway

Journal of Neurochemistry, ISSN: 00223042

Hugh J. L. Fryer; Daniel H. Wolf; Ronald J. Knox; Stephen M. Strittmatter; Diane Pennica; O'Leary; David S. Russell; Robert G. Kalb

View on Scopus

January 25, 2000

Green fluorescent protein as a second selectable marker for selection of high producing clones from transfected CHO cells

Gene, ISSN: 03781119

Meng; Jie Liang; Wai Lee T. Wong; Chisholm

View on Scopus

January 24, 2000

Cytokine-induced nuclear factor kappa B activation promotes the survival of developing neurons

Journal of Cell Biology, ISSN: 00219525

Gayle Middleton; Makoto Hamanoue; Yasushi Enokido; Sean Wyatt; Diane Pennica; Ellis Jaffray; Ronald T. Hay; Alun M. Davies

View on Scopus

January 20, 2000

Coarse spray delivery to a localized region of the pulmonary airways for gene therapy

Human Gene Therapy, ISSN: 10430342

Cipolla; Gonda; Steven Shak; Kovesdi; Crystal; Sweeney

View on Scopus

January 18, 2000

Cloning and characterization of IL-17B and IL-17C, two new members of the IL-17 cytokine family

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Hanzhong Li; Jian Chen; Arthur Huang; Stinson; Sherry Heldens; Foster; Patrick Dowd; Austin L. Gurney; William I. Wood

View on Scopus

January 17, 2000

RGD mimetics containing a central hydantoin scaffold: α(v)β3 vs α(IIb)β3 selectivity requirements

Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X

Peyman; Volkmar Wehner; Knolle; Stilz; Breipohl; Karl-Heinz Scheunemann; Denis Carniato; Ruxer; Gourvest; Thomas Gadek; Bodary

View on Scopus

January 15, 2000

A highly conserved enhancer in the Dlx5/Dlx6 intergenic region is the site of cross-regulatory interactions between Dlx genes in the embryonic forebrain

Journal of Neuroscience, ISSN: 02706474

Ted Zerucha; Thorsten Stühmer; Gary Hatch; Byung K. Park; Qiaoming Long; Guoying Yu; Adrianna Gambarotta; Joshua R. Schultz; John L. R. Rubenstein; Marc Ekker

View on Scopus

January 15, 2000

Kistrin inhibits human smooth muscle cell interaction with fibrin

Thrombosis Research, ISSN: 00493848

Karen O Yee; Yuji Ikari; Bodary; Schwartz

View on Scopus

January 11, 2000

Characterization of the binding interface between the E-domain of Staphylococcal protein A and an antibody Fv-fragment

Biochemistry, ISSN: 00062960

David Meininger; Mark Rance; Melissa A. Starovasnik; Wayne J. Fairbrother; Nicholas J. Skelton

View on Scopus

January 1, 2000

Comparison of the rates of deamidation, diketopiperazine formation, and oxidation in recombinant human vascular endothelial growth factor and model peptides

AAPS PharmSci, ISSN: 15221059

Chimanlall Goolcharran; Andrew J.S. Jones; Ronald T. Borchardt; Cleland; Rodney Keck

View on Scopus

January 1, 2000

Drug information in industry versus academia: A pharmacy resident's perspective of a sample case

Therapeutic Innovation and Regulatory Science, ISSN: 21684790

Graham; David A. Graves; Barry Grobman; Gary M. Mccart; Candy Tsourounis

View on Scopus

January 1, 2000

Purification of yeast mitochondrial Hsp60.

Methods in Molecular Biology, ISSN: 10643745

Yves Dubaquié; Renate Looser; Sabine Rospert

View on Scopus

January 1, 2000

Mice lacking α-synuclein display functional deficits in the nigrostriatal dopamine system

Neuron, ISSN: 08966273

Asa Abeliovich; Yvonne Schmitz; Isabel Fariñas; Choi-Lundberg; Ho; Pablo E. Castillo; Natasha Shinsky; Jose Manuel Garcia-Verdugo; Armanini; Anne Ryan; Mary Hynes; Phillips; David Sulzer; Rosenthal

View on Scopus

January 1, 2000

Pharmacokinetics and pharmacodynamics of tenecteplase: Results from a phase II study in patients with acute myocardial infarction

Journal of Clinical Pharmacology, ISSN: 00912700

Modi; Fox; Fong-Wong Clow; Tanswell; Christopher P. Cannon; Frans Van De Werf; Eugene Braunwald

View on Scopus

January 1, 2000

Toll-like receptor 2-mediated NF-κB activation requires a Rac I-dependent pathway

Nature Immunology, ISSN: 15292908

Laurence Arbibe; Jean-Paul Mira; Nicole Teusch; Lois Kline; Mausumee Guha; Nigel Mackman; Godowski; Richard J. Ulevitch; Ulla G. Knaus

View on Scopus

January 1, 2000

Gene expression profiling in an in vitro model of angiogenesis

American Journal of Pathology, ISSN: 00029440

Jeanne Kahn; Fuad Mehraban; Gladys S. Ingle; Xiaohua Xin; Juliet E. Bryant; Gordon A. Vehar; Schoenfeld; Grimaldi; Franklin V. Peale Jr.; Aparna Draksharapu; Lewin; Mary E. Gerritsen

View on Scopus

January 1, 2000

Clonidine for smoking cessation.

Cochrane database of systematic reviews (Online : Update Software), ISSN: 1469493X

Steven G. Gourlay; Stead; Neal L. Benowitz

View on Scopus

January 1, 2000

The nucleoskeleton: Go EAST, young man

Nature Cell Biology, ISSN: 14657392

Lasky

View on Scopus

January 1, 2000

The seven-transmembrane receptor Smoothened cell-autonomously induces multiple ventral cell types

Nature Neuroscience, ISSN: 10976256

Mary Hynes; Weilan Ye; Kevin Wang; Donna Stone; Maximilien Murone; Frederic J. De Sauvage; Rosenthal

View on Scopus

January 1, 2000

Angiography of fluoresceinated anti-vascular endothelial growth factor antibody and dextrans in experimental choroidal neovascularization

Archives of Ophthalmology, ISSN: 00039950

Michael J. Tolentino; Deeba Husain; Panagiotis Theodosiadis; Evangelos S. Gragoudas; Edward Connolly; Jeanne Kahn; Cleland; Anthony P. Adamis; R. Andrew Cuthbertson; Joan W. Miller

View on Scopus

January 1, 2000

Analysis of PTCH/SMO/SHH pathway genes in medulloblastoma

Genes Chromosomes and Cancer, ISSN: 10452257

Russell H. Zurawel; Cory Allen; Sharon Chiappa; Walter Cato; Jaclyn Biegel; Philip Cogen; Frederic J. De Sauvage; Corey Raffel

View on Scopus

January 1, 2000

Concomitant over-expression of vascular endothelial growth factor and its receptors in pancreatic cancer

International Journal of Cancer, ISSN: 00207136

Jun Itakura; Toshiyuki Ishiwata; Shen; Marko Kornmann; Murray Korc

View on Scopus