Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 12501 - 12550 OF 15583 RESULTS

January 1, 1998

Crystallization and preliminary X-ray analysis of a 1:1 complex between a designed monomeric interferon-gamma and its soluble receptor

Protein Science, ISSN: 09618368

Michael Randal; Anthony A. Kossiakoff

January 1, 1998

Short communication: Renal tubular vacuolation in animals treated with polyethylene-glycol-conjugated proteins

Toxicological Sciences, ISSN: 10966080

Alison Bendele; Jim Seely; Carl Richey; Gina Sennello; Shopp

January 1, 1998

Cardiotrophin-1 induces heat shock protein accumulation in cultured cardiac cells and protects them from stressful stimuli

Journal of Molecular and Cellular Cardiology, ISSN: 00222828

Anastatis Stephanou; Bhawanjit K. Brar; Heads; Knight; Marber; Diane Pennica; David S. Latchman

January 1, 1998

Maintenance of myonuclear domain size in rat soleus after overload and growth hormone/IGF-I treatment

Journal of Applied Physiology, ISSN: 87507587

McCall; Allen; Jon K. Linderman; Richard E. Grindeland; Roy; Mukku; Edgerton

January 1, 1998

Humanization of an antibody against human protein C and calcium-dependence involving framework residues

Protein Engineering, ISSN: 02692139

Shane J. O'Connor; Meng; Alireza R. Rezaie; Presta

January 1, 1998

Inorganic polyphosphate in Escherichia coli: The phosphate regulon and the stringent response

Journal of Bacteriology, ISSN: 00219193

Narayana N. Rao; Shengjiang Liu; Arthur Kornberg

January 1, 1998

Inhibin gene expression in a large cell calcifying Sertoli cell tumour and serum inhibin and activin levels

APMIS, ISSN: 09034641

Jorma Toppari; Antti Kaipia; Marko Kaleva; Matti Laato; David M. De Kretser; Lynne Krummen; Mather; Toivo T. Salmi

January 1, 1998

Comparison of VEGF delivery techniques on collateral-dependent microvascular reactivity

Microvascular Research, ISSN: 00262862

Frank W Sellke; Motohisa Tofukuji; Roger J Laham; Jianyi Li; Mukesh D. Hariawala; Bunting; Michael Simons

January 1, 1998

A cell-based potency assay for insulin-like growth factor-I

Biologicals, ISSN: 10451056

Hélène Gazzano-Santoro; Chen; Mukku

January 1, 1998

Hematopoietic deficiencies in c-mpl and TPO knockout mice

Stem Cells, ISSN: 10665099

Maximilien Murone; David Carpenter; Frederic J. De Sauvage

January 1, 1998

Endogenous serum thrombopoietin concentrations in patients with myelodysplastic syndromes

Leukemia, ISSN: 08876924

Heinz Zwierzina; Rollinger-Holzinger; Nuessler; Herold; Meng

January 1, 1998

Persephin, a novel neurotrophic factor related to GDNF and neurturin

Neuron, ISSN: 08966273

Jeffrey Milbrandt; Frederic J. De Sauvage; Timothy J. Fahrner; Robert H. Baloh; Melanie L. Leitner; Malú G. Tansey; Patricia A. Lampe; Robert O. Heuckeroth; Paul T. Kotzbauer; Kelli S. Simburger; Judith P. Golden; Jamie A. Davies; Richard Vejsada; Ann C. Kato; Mary Hynes; Sherman; Merry Nishimura; Li-Chong Wang; Richard L. Vandlen; Moffat; Robert D. Klein; Kris Poulsen; Christa Gray; Alain Garces; Christopher E. Henderson; Phillips; Eugene M. Johnson Jr.

January 1, 1998

Spray-drying of air-liquid interface sensitive recombinant human growth hormone

Journal of Pharmaceutical Sciences, ISSN: 00223549

Maa; Phuong-Anh Nguyen; Selena W. Hsu

January 1, 1998

Auto transplants for Parkinson's disease?

Neuron, ISSN: 08966273

Rosenthal

January 1, 1998

Disaccharide analysis of heparin and heparan sulfate using deaminative cleavage with nitrous acid and subsequent labeling with paranitrophenyl hydrazine

Journal of Biochemistry, ISSN: 0021924X

Yutaka Kariya; Jörg Herrmann; Kiyoshi Suzuki; Takako Isomura; Masayuki Ishihara

January 1, 1998

Biological aspects of the intestinal epithelial barrier

Proceedings of the Controlled Release Society, ISSN: 10220178

Mrsny

January 1, 1998

Pharmacokinetics of a slower clearing tissue plasminogen activator variant, TNK-tPA, in patients with acute myocardial infarction

Thrombosis and Haemostasis, ISSN: 03406245

Modi; Stephen M. Eppler; Judy Breed; Christopher P. Cannon; Eugene Braunwald; Ted W. Love

January 1, 1998

Amino acid sequence similarity of Hev b 3 to two previously reported 27- and 23-kDa latex proteins allergenic to spina bifida patients

Allergy: European Journal of Allergy and Clinical Immunology, ISSN: 01054538

Yeang; Ward; Zamri; Dennis; Light

January 1, 1998

Activating Smoothened mutations in sporadic basal-cell carcinoma

Nature, ISSN: 00280836

Jingwu Xie; Maximilien Murone; Shiuh-Ming Luoh; Anne Ryan; Qimin Gu; Chaohui Zhang; Jeannette M. Bonifas; Ching-Wan Lam; Mary Hynes; Goddard; Rosenthal; Ervin H. Epstein Jr.; Frederic J. De Sauvage

January 1, 1998

Fourier-transform infrared spectroscopic investigation of the secondary structure of aqueous and dried recombinant human deoxyribonuclease I

Pharmacy and Pharmacology Communications, ISSN: 14608081

Henry R. Costantino; Bei Chen; Kai Griebenow; Chung C. Hsu; Steven J. Shire

January 1, 1998

Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear

Mechanisms of Development, ISSN: 09254773

Lewis; Gretchen D. Frantz; David Carpenter; Frederic J. De Sauvage; Gao

January 1, 1998

AtDB, the Arabidopsis thaliana Database, and graphical-web-display of progress by the Arabidopsis genome initiative

Nucleic Acids Research, ISSN: 03051048

David J. Flanders; Shuai Weng; Fabien X. Petel; J. Michael Cherry

January 1, 1998

Mucoadhesive microparticles for antigen delivery

Proceedings of the Controlled Release Society, ISSN: 10220178

Claudia Witschi; Mrsny

January 1, 1998

Mucosal administration of a non-toxic Pseudomonas exotoxin-gp120 V3 loop chimera elevates gp120 specific IgG and IgA in the serum and saliva of BALB/c mice

Proceedings of the Controlled Release Society, ISSN: 10220178

Daugherty; Silva; Charlotte M. Fryling; David FitzGerald; Mrsny

January 1, 1998

Substantially attenuated hemodynamic responses to Escherichia coli- derived vascular endothelial growth factor given by intravenous infusion compared with bolus injection

Journal of Pharmacology and Experimental Therapeutics, ISSN: 00223565

Renhui Yang; Bunting; Annie Ko; Keyt; Modi; Zioncheck; Napoleone Ferrara; Hongkui Jin

January 1, 1998

Computer system validation: Value added activities meeting regulatory imperatives

Drug Information Journal, ISSN: 00928615

Woodrum

January 1, 1998

Effects of cardiotrophin-1 on haemodynamics and cardiac function in conscious rats

Cytokine, ISSN: 10434666

Hongkui Jin; Renhui Yang; Ko Annie; Diane Pennica; William I. Wood; Nicholas F. Paoni

January 1, 1998

Lymphocyte granule-mediated apoptosis: Matters of viral mimicry and deadly proteases

Immunology Today, ISSN: 01675699

Christopher J. Froelich; Vishva M. Dixit; Xiaohe Yang

January 1, 1998

Solvent evaporation processes for the production of controlled release biodegradable microsphere formulations for therapeutics and vaccines

Biotechnology Progress, ISSN: 87567938

Cleland

January 1, 1998

Nab1, a corepressor of NGFI-A (Egr-1), contains an active transcriptional repression domain

Molecular and Cellular Biology, ISSN: 02707306

Alex H. Swirnoff; Elizabeth D. Apel; John Svaren; Bradley R. Sevetson; Drazen B. Zimonjic; Nicholas C. Popescu; Jeffrey Milbrandt

January 1, 1998

Calcium-phosphate mediated DNA transfer into HEK-293 cells in suspension: Control of physicochemical parameters allows transfection in stirred media: Transfection and protein expression in mammalian cells

Cytotechnology, ISSN: 09209069

Martin Jordan; Christiane Köhne; Florian M. Wurm

January 1, 1998

Integrins α(v)β3 and α5β1 mediate attachment of lyme disease spirochetes to human cells

Infection and Immunity, ISSN: 00199567

Jenifer Coburn; Loranne Magoun; Bodary; John M. Leong

January 1, 1998

Chromatography in biotechnology: A user's perspective

LC-GC Europe, ISSN: 14716577

John Frenz

January 1, 1998

Stabilization of nerve growth factor during microencapsulation and release from microspheres

Proceedings of the Controlled Release Society, ISSN: 10220178

Lam; Duenas; Cleland

January 1, 1998

Requirement for Brn-3c in maturation and survival, but not in fate determination of inner ear hair cells

Development (Cambridge), ISSN: 09501991

Mengqing Xiang; Gao; Tama Hasson; Joyce J. Shin

January 1, 1998

Development of stable formulations for PLGA/PLA microsphere vaccines

Research in Immunology, ISSN: 09232494

Cleland

January 1, 1998

Pharmacokinetics, pharmacodynamics and tolerability of a potent, non-peptidic, GP IIb/IIIa receptor antagonist following multiple oral administrations of a prodrug form

Thrombosis and Haemostasis, ISSN: 03406245

Refino; Modi; Sherron L. Bullens; Cheryl Pater; Michael T. Lipari; Kirk D. Robarge; Brent Blackburn; Beresini; Thomas Weller; Beat Steiner; Bunting

January 1, 1998

Local delivery of vascular endothelial growth factor via PLGA depots for treatment of vascular disease

Proceedings of the Controlled Release Society, ISSN: 10220178

Ann Park; Duenas; Thomas W. Patapoff; Cleland

January 1, 1998

A data model for clinical study status reports

Drug Information Journal, ISSN: 00928615

David H. Christiansen; Sundin

January 1, 1998

Genetic approaches to the detection of contaminants in Escherichia coli fermentations

Biotechnology Progress, ISSN: 87567938

James R. Swartz; Nancy McFarland

January 1, 1998

Increased physical activity and the growth hormone-IGF-I axis in adolescent males

American Journal of Physiology - Regulatory Integrative and Comparative Physiology, ISSN: 03636119

Alon Eliakim; Jo Anne Brasel; Subburaman Mohan; Wai Lee T. Wong; Dan M. Cooper

January 1, 1998

Fast Edman cycles with accelerated PTH analysis

Protein Journal, ISSN: 18758355 15723887

William J. Henzel; Jake Tropea; Kishiyama; Wendy Shillinglaw; David Dupont; Steve O'Neil

January 1, 1998

A role for FADD in T cell activation and development

Immunity, ISSN: 10747613

Craig M. Walsh; Ben G. Wen; Arul M. Chinnaiyan; Karen M. O'Rourke; Vishva M. Dixit; Stephen M. Hedrick

January 1, 1998

Development and validation of the migraine-specific quality of life questionnaire

Headache, ISSN: 00178748

Priti Jhingran; Jane T. Osterhaus; David W. Miller; Jeffrey T. Lee; Leonard Kirchdoerfer

January 1, 1998

Development of a single-shot subunit vaccine for HIV-1. 5. Programmable in vivo autoboost and long lasting neutralizing response

Journal of Pharmaceutical Sciences, ISSN: 00223549

Cleland; Lim; Daugherty; Barron; Noelyn Desardin; Duenas; Eastman; Vennari; Wrin; Berman; Michael Powel

January 1, 1998

Adaptation to hyperglycemia enhances insulin secretion in glucokinase mutant mice

Diabetes, ISSN: 00121797

Seamus K. Sreenan; Brian N. Cockburn; Aaron C. Baldwin; Diane M. Ostrega; Matteo Levisetti; Andrew Grupe; Graeme I. Bell; Stewart; Michael W. Roe; Kenneth S. Polonsky

January 1, 1998

Raw materials as a source of contamination in large-scale cell culture.

Developments in biological standardization, ISSN: 03015149

Robert L. Garnick

January 1, 1998

Biological response to ErbB ligands in nontransformed cell lines correlates with a specific pattern of receptor expression

Endocrinology, ISSN: 00137227

Sundaresan; Penelope E. Roberts; King; Mark X. Sliwkowski; Mather

January 1, 1998

Therapeutic potential of neurotrophins for treatment of hearing loss

Molecular Neurobiology, ISSN: 08937648

Gao

January 1, 1998

The dormant in vivo phenotype of early stage primary human melanoma: Termination by overexpression of vascular endothelial growth factor

Angiogenesis, ISSN: 09696970

Liisa Bayko; Janusz Rak; Shan Man; Roy Bicknell; Napoleone Ferrara; Robert S. Kerbel

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