Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 12801 - 12850 OF 15796 RESULTS

January 1, 1998

IL-3 does not contribute to platelet production in c-Mpl-deficient mice.

Stem Cells, ISSN: 10665099

Qi Chen; Gregg Solar; Dan L. Eaton; Frederic J. De Sauvage

January 1, 1998

Dosing, monitoring, and safety of growth hormone-replacement therapy in adults with growth hormone deficiency

Endocrinologist, ISSN: 10512144

Sandra L. Blethen

January 1, 1998

Expression of active human tissue-type plasminogen activator in Escherichia coli

Applied and Environmental Microbiology, ISSN: 00992240

Ji Qiu; James R. Swartz; George Georgiou

January 1, 1998

Effect of mannitol crystallization on the stability and aerosol performance of a spray-dried pharmaceutical protein, recombinant humanized anti-lge monoclonal antibody

Journal of Pharmaceutical Sciences, ISSN: 00223549

Henry R. Costantino; Andya; Phuong-Anh Nguyen; Nancy Dasovich; Sweeney; Steven J. Shire; Chung C. Hsu; Maa

January 1, 1998

Deterioration of lyophilized pharmaceutical proteins

Biochemistry (Moscow), ISSN: 00062979

Henry R. Costantino; Schwendeman; Langer; Klibanov

January 1, 1998

Recombinant human thrombopoietin clinical development.

Stem Cells, ISSN: 10665099

Jones Jr.; Ashby; Saroj Vadhan-Raj; Somlo; Richard Champlin; Gajewski; Hellmann; Gwendolyn Fyfe

January 1, 1998

Genentech and breast cancer advocacy

Breast Disease, ISSN: 08886008

Steven Shak; Bales; Sharon A. Baughman; John G. Curd; Henry J. Fuchs; Perry; Teeter; Leber

January 1, 1998

Simultaneous measurement of cell cycle and apoptotic cell death

Methods in Cell Biology, ISSN: 0091679X

Alison Moore; Christopher J. Donahue; Kenneth D. Bauer; Mather

January 1, 1998

Statistical methods for dna sequence segmentation

Statistical Science, ISSN: 08834237

Jerome V. Braun; Hans-Georg Müller

January 1, 1998

Laboratory scaleup of cell cultures (0.5-50 liters)

Methods in Cell Biology, ISSN: 0091679X

Mather

January 1, 1998

The human growth hormone saga.

Developments in biological standardization, ISSN: 03015149

Eleanor Canova-Davis

January 1, 1998

rtPA is a well-characterized protein.

Developments in biological standardization, ISSN: 03015149

O'Connor

January 1, 1998

Behavioral and cellular protection of rat dopaminergic neurons by an adenoviral vector encoding glial cell line-derived neurotrophic factor

Experimental Neurology, ISSN: 00144886

Choi-Lundberg; Qing Lin; Tim Schallert; Donita Crippens; Beverly L. Davidson; Yung-Nien Chang; Yawen L. Chiang; Jiang Qian; Leena Bardwaj; Martha C. Bohn

January 1, 1998

Adjuvants and delivery issues related to immunization: A survey of the recent patent literature

Journal of Drug Targeting, ISSN: 1061186X

Mrsny

January 1, 1998

Crystallization of ovine placental lactogen in a 1:2 complex with the extracellular domain of the rat prolactin receptor

Acta Crystallographica Section D: Biological Crystallography, ISSN: 09074449

Hans W. Christinger; Patricia A. Elkins; Yael Sandowski; Edna Sakal; Arieh Gertler; Anthony A. Kossiakoff; De Vos

January 1, 1998

The efficacy of recombinant thrombopoietin in murine and nonhuman primate models for radiation-induced myelosuppression and stem cell transplantation

Stem Cells, ISSN: 10665099

Gerard Wagemaker; Karen J. Neelis; Simone C. C. Hartong; Albertus W. Wognum; G. Roger Thomas; Fielder; Dan L. Eaton

January 1, 1998

Detection of mycoplasmas in cell cultures by cultural methods.

Methods in Molecular Biology, ISSN: 10643745

Masover; Becker

January 1, 1998

Detection of mycoplasmas in cell cultures by fluorescence methods.

Methods in Molecular Biology, ISSN: 10643745

Masover; Becker

January 1, 1998

Combination of bone marrow and tgf-/j1 augment the healing of critical-sized bone defects

Journal of Pharmaceutical Sciences, ISSN: 00223549

Tue H. Nguyen

January 1, 1998

Inspiratory flow rate and dynamic lung function in cystic fibrosis and chronic obstructive lung diseases

Chest, ISSN: 00123692

Priscilla S. A. Sarinas; Terry E. Robinson; Clark; James Canfield Jr.; Rajinder K. Chitkara; Robert B. Fick Jr.

January 1, 1998

How much insulin-like growth factor I (IGF-I) circulates? Impact of standardization on IGF-I assay accuracy

Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X

Quarmby; Quan; Victor Ling; Peter G. Compton; Eleanor Canova-Davis

January 1, 1998

Treatment of glucocorticoid-induced growth suppression with growth hormone

Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X

David B. Allen; Joanne R. Julius; Timothy J. Breen; Kenneth M. Attie

January 1, 1998

Structural basis for cytokine hormone-receptor recognition and receptor activation

Advances in Protein Chemistry, ISSN: 00653233

Anthony A. Kossiakoff; De Vos

January 1, 1998

A role for FADD in T cell activation and development

Immunity, ISSN: 10747613

Craig M. Walsh; Ben G. Wen; Arul M. Chinnaiyan; Karen M. O'Rourke; Vishva M. Dixit; Stephen M. Hedrick

January 1, 1998

Development and validation of the migraine-specific quality of life questionnaire

Headache, ISSN: 00178748

Priti Jhingran; Jane T. Osterhaus; David W. Miller; Jeffrey T. Lee; Leonard Kirchdoerfer

January 1, 1998

Fast Edman cycles with accelerated PTH analysis

Protein Journal, ISSN: 18758355 15723887

William J. Henzel; Jake Tropea; Kishiyama; Wendy Shillinglaw; David Dupont; Steve O'Neil

December 19, 1997

Determination of Ro 48-3656 in rat plasma by reversed-phase high-performance liquid chromatography. Comparison of 1.5-μm nonporous silica to 3.5-μm porous silica analytical columns

Journal of Chromatography B: Biomedical Applications, ISSN: 15726495

Paasch; Yvonne S. Lin; Seth Porter; Modi; Timothy J. Barder

December 15, 1997

The effect of size, charge and cyclization of model peptides on their in vitro release from DL-PLGA microspheres

Journal of Controlled Release, ISSN: 01683659

Okumu; Cleland; Ronald T. Borchardt

December 15, 1997

Recombinant human growth hormone poly(lactic-co-glycolic acid) (PLGA) microspheres provide a long lasting effect

Journal of Controlled Release, ISSN: 01683659

Cleland; Duenas; Daugherty; Marian; Yang; Wilson; Abbie Celniker; Shahzamani; Quarmby; Chu; Mukku; Mac; Roussakis; Nancy Gillette; Brooks Boyd; Yeung; Brooks; Maa; Chung C. Hsu; Andrew J.S. Jones

December 12, 1997

Heregulins and the ErbB-2/3/4 receptors in gliomas

Journal of Neuro-Oncology, ISSN: 0167594X

Manfred Westphal; Leonie Meima; Szonyi; Julie A. Lofgren; Meissner; Wolfgang Hamel; Nikolics; Mark X. Sliwkowski

December 9, 1997

Inhibition of HIV type 1 infectivity by constrained α-helical peptides: Implications for the viral fusion mechanism

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

J. Kevin Judice; Jeffrey Tom; Wei Huang; Wrin; Vennari; Christos J. Petropoulos; Robert S. McDowell

December 9, 1997

A family of genes required for maintenance of cell wall integrity and for the stress response in Saccharomyces cerevisiae

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

James Verna; Adriana Lodder; Kyunghee Lee; Alicia Vagts; Roymarie Ballester

December 1, 1997

Therapeutic monoclonal as the treatment of allergic disease

Proceedings of the Western Pharmacology Society, ISSN: 00838969

Paula Jardieu

December 1, 1997

Engineered receptor cytoplasmic domains with fixed signal output: Probing mechanism with design

FASEB Journal, ISSN: 08926638

Andrea G Cochran

December 1, 1997

Hemodynamic effects of scatter factor in conscious rats

FASEB Journal, ISSN: 08926638

Hongkui Jin; Renhui Yang; Annie Ko; Ralph H. Schwall; Bunting

December 1, 1997

ErbB3 is required for normal cerebellar and cardiac development: A comparison with ErbB2- and heregulin-deficient mice

Development (Cambridge), ISSN: 09501991

Sharon Erickson; Sue O'Shea; Nazli Ghaboosi; Linda Loverro; Gretchen D. Frantz; Michele Bauer; Lucy Lu; Mark Moore

December 1, 1997

Potent biflnctional anticoagulants: kunitz domain - tissue factor fusion proteins

FASEB Journal, ISSN: 08926638

Geoffrey F. Lee

December 1, 1997

How integrins are activated

Nature, ISSN: 00280836

Lasky

December 1, 1997

Intravenous infusion of vascular endothelial growth factor (VEGF) substantially attenuates its hemodynamic effects

FASEB Journal, ISSN: 08926638

Renhui Yang; Bunting; Annie Ko; Keyt; Napoleone Ferrara; Hongkui Jin

December 1, 1997

Inhibition of angiogenesis by blocking vegf action: mutational analysis of vegf:receptor binding and epitope mapping of neutralizing antibodies

Fibrinolysis and Proteolysis, ISSN: 13690191

Keyt

December 1, 1997

Neutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in vitro and in vivo: Angiogenic implications for signal transduction therapy of solid tumors

American Journal of Pathology, ISSN: 00029440

Alicia M. Viloria Petit; Janusz Rak; Mien-Chie Hung; Patricia Rockwell; Neil Goldstein; Brian M. Fendly; Robert S. Kerbel

December 1, 1997

Hemodynamic effects of scatter factor in conscious rats

Journal of Cardiovascular Pharmacology, ISSN: 01602446

Renhui Yang; Bunting; Annie Ko; Ralph H. Schwall; Hongkui Jin

December 1, 1997

RhDNase I is a well characterized protein

Pharmaceutical Sciences, ISSN: 13566881

Quan; Cacia; John Frenz; O'Connor

December 1, 1997

Engineering hyperactive human DNASE I with over 4000-fold higher activity in human serum

Protein Engineering, ISSN: 02692139

Pan; Tony H. Dodge; Baker; Sinicropi; Lazarus

December 1, 1997

Identification of components of the cell death pathway

Fibrinolysis and Proteolysis, ISSN: 13690191

Vishva M. Dixit

December 1, 1997

Native fluorescence detection of recombinant human growth hormone resolve from E. coli cell paste extract by capillary zone electrophoresls

FASEB Journal, ISSN: 08926638

McNerney; Robert L. Bridenbaugh

December 1, 1997

Metabolic labeling for monitoring sialylation of recombinant proteins in growing chinese hamster ovary cell cultures

FASEB Journal, ISSN: 08926638

Santeli; Ryll Twang; Jane Gunson; Warner

December 1, 1997

A novel receptor for Apo2L/TRAIL contains a truncated death domain

Current Biology, ISSN: 09609822

Scot A. Marsters; James P. Sheridan; Pitti; Arthur Huang; Skubatch; Daryl T. Baldwin; Jean Q. Yuan; Austin L. Gurney; Goddard; Godowski; Avi Ashkenazi

December 1, 1997

Evaluation of ABRF-96SEQ: A sequence assignment exercise

Techniques in Protein Chemistry, ISSN: 10808914

Joseph Fernandez; Arie Admon; Karen De Jongh; Greg Grant; William J. Henzel; William Lane; Kathryn Stone; Barbara Merrill

December 1, 1997

Pharmacokinetics and dynamics of longer half-life and pai-1 resistant tissue plasminogen activator mutants: slow clearing molecules are not rapidly inhibited

Fibrinolysis and Proteolysis, ISSN: 13690191

Bruce A. Kevtt; Lea Berleau; Hung V. Nguyen; Stephen Epplerf; Nishit Modif

Join Our Team

The little things we do every day add up to big breakthroughs. Making a difference in the lives of millions starts when you make a change in yours.

Two Scientists Walk Into a Bar

Two Scientists Walk Into a Bar

Listen to our podcast, where researchers talk about their work answering the toughest questions in human biology.