Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 13701 - 13750 OF 15796 RESULTS

Interleukin-8 receptor β. The role of the carboxyl terminus in signal transduction
Journal of Biological Chemistry, ISSN: 00219258
Adit Ben-Baruch; Kathleen M. Bengali; Arya Biragyn; Jim J. Johnston; Ji-Ming Wang; Jin Kim; Anan Chuntharapai; Dennis F. Michiel; Joost J. Oppenheim; David J. Kelvin
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Thrombopoietin and the humoral regulation of thrombocytopoiesis.
Current Opinion in Hematology, ISSN: 10656251
Dan L. Eaton; Frederic J. De Sauvage
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Medical aerosol inhalers: Past, present, and future
Aerosol Science and Technology, ISSN: 15217388 02786826
Clark
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Cardiotrophin-1. Biological activities and binding to the leukemia inhibitory factor receptor/gp130 signaling complex
Journal of Biological Chemistry, ISSN: 00219258
Diane Pennica; Kenneth J. Shaw; Todd A. Swanson; Mark Moore; David L. Shelton; Kimberly Zioncheck; Rosenthal; Tetsuya Taga; Nicholas F. Paoni; William I. Wood
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Neurotrophins and neurotrophin antagonists as potential therapeutics
Restorative Neurology and Neuroscience, ISSN: 18783627 09226028
David L. Shelton; McMahon; Winslow; Wei-Qiang Qao
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Structure of the growth hormone-receptor complex and mechanism of receptor signaling.
Journal of Nuclear Medicine, ISSN: 01615505
Anthony A. Kossiakoff
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Neurotrophin‐3 reverses experimental cisplatin‐induced peripheral sensory neuropathy
Annals of Neurology, ISSN: 15318249 03645134
Gao; Noel Dybdal; Natasha Shinsky; Amy Murnane; Charles H. Schmelzer; Mark Siegel; Gilbert-Andre Keller; Franz Hefti; Phillips; Winslow
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Affinity Purification and Microcharacterization of Recombinant DNA-Derived Human Growth Hormone Isolated from an in Vivo Model
Analytical Chemistry, ISSN: 15206882 00032700
John E. Battersby; Venkat R. Mtikku; Rose G. Clark; William S. Hancock
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Stabilization of Type-I β-Turn Conformations in Peptides Containing the NPNA-Repeat Motif of the Plasmodium falciparum Circumsporozoite Protein by Substituting Proline for (S)-α-Methylproline
Journal of the American Chemical Society, ISSN: 15205126 00027863
Christian Bisang; Christoph Weber; Janice Inglis; Wilfred F. Van Gunsteren; Celia A. Schiffer; Ilian Jelesarov; Hans R. Bosshard; John A. Robinson
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Induction of midbrain dopaminergic neurons by Sonic hedgehog
Neuron, ISSN: 08966273
Mary Hynes; Jeffery A. Porter; Chin Chiang; David Chang; Marc Tessier-Lavigne; Philip A. Beachy; Rosenthal
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Engineering high affinity humanized anti‐p185HER2/anti‐CD3 bispecific F(ab′)2 for efficient lysis of p185HER2 overexpressing tumor cells
International Journal of Cancer, ISSN: 10970215 00207136
Zhu; Gail D. Lewis; Paul J. Carter
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Immunohistochemical Visualization of Brain‐derived Neurotrophic Factor in the Rat Brain
European Journal of Neuroscience, ISSN: 14609568 0953816X
Dugich-Djordjevic; Christine Peterson; Fujio Isono; Fukuichi Ohsawa; Hans R. Widmer; Denton; Bennett; Franz Hefti
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Binding and cross-linking of 32p-labeled human relaxin to human uterine cells and primary rat atrial cardiomyocytes
Endocrinology, ISSN: 19457170 00137227
Phyllis L. Osheroff; King
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The Regulation of Blood Vessel Growth by Vascular Endothelial Growth Factor
Annals of the New York Academy of Sciences, ISSN: 17496632 00778923
Napoleone Ferrara; Heinsohn; Walder; Bunting; G. Roger Thomas
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Cloning, sequencing, and expression of a 24-kDa Ca2+-binding protein activating photoreceptor guanylyl cyclase
Journal of Biological Chemistry, ISSN: 00219258
Alexander M. Dizhoor; Elena V. Olshevskaya; William J. Henzel; Susan C. Wong; Stults; Irina Ankoudinova; James B. Hurley
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Enzymatic Cyclization of Linear Peptide Esters Using Subtiligase
Journal of the American Chemical Society, ISSN: 15205126 00027863
Jackson; Burnier; James A. Wells
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Neurotrophin‐4/5, brain‐derived neurotrophic factor, and neurotrophin‐3 promote survival of cultured vestibular ganglion neurons and protect them against neurotoxicity of ototoxins
Journal of Neurobiology, ISSN: 10974695 00223034
Lisa Zheng; Randall R. Stewart; Gao
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Designing Subtilisin BPN’ To Cleave Substrates Containing Dibasic Residues
Biochemistry, ISSN: 15204995 00062960
Ballinger; Jeffrey Torn; James A. Wells
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In vitro characterization of four novel classes of growth hormone-releasing peptide
Endocrinology, ISSN: 19457170 00137227
Kathleen A. Elias; Gladys S. Ingle; Burnier; R. Glenn Hammonds; Robert S. Mc dowell; Thomas E. Rawson; Todd C. Somers; Mark S. Stanley; Cronin
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Development of antimalaria immunity in mice lacking IFN-γ receptor
Journal of Immunology, ISSN: 00221767
Moriya Tsuji; Yasushi Miyahira; Ruth S. Nussenzweig; Michel Aguet; Reichel; Fidel Zavala
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Correlation of cleavage techniques with side-reactions following solid-phase peptide synthesis
Techniques in Protein Chemistry, ISSN: 10808914
Gregg B. Fields; Ruth H. Angeletti; Lynda F. Bonewald; William T. Moore; Alan J. Smith; Stults; Lynn C. Williams
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Time course of increased cellular proliferation collateral arteries after administration of vascular endothelial growth factor in a rabbit model of lower limb vascular insufficiency
American Journal of Pathology, ISSN: 00029440
Satoshi Takeshita; Susan T. Rossow; Marianne Kearney; Lu P. Zheng; Christophe Bauters; Bunting; Napoleone Ferrara; James F. Symes; Jeffrey M. Isner
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Characterization of Complex Formation by Humanized Anti-IgE Monoclonal Antibody and Monoclonal Human IgE
Biochemistry, ISSN: 15204995 00062960
Jun Liu; Philip M. Lester; Stuart E. Builder; Steven J. Shire
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Ligand Binding to the Tissue-Type Plasminogen Activator Kringle 2 Domain: Structural Characterization by 1H-NMR
Biochemistry, ISSN: 15204995 00062960
In-Ja L. Byeon; Robert F. Kelley; Michael G. Mulkerrin; Seong Soo A. An; Miguel Llinás
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The unexpected presence of hydroxylysine in non-collagenous proteins
Techniques in Protein Chemistry, ISSN: 10808914
Michael S. Molony; Wu; Lene K. Keyt; Reed J. Harris
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Exploring the Role of the Solvent in the Denaturation of a Protein: A Molecular Dynamics Study of the DNA Binding Domain of the 434 Repressor
Biochemistry, ISSN: 15204995 00062960
Celia A. Schiffer; Volker Dötsch; Kurt Wüthrich; Wilfred F. Van Gunsteren
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Structural and functional epitopes in the growth hormone receptor complex: Can information from large molecules lead to the design of small molecule mimetics?
Nature Biotechnology, ISSN: 0733222X
James A. Wells
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Cloning of the Murine Counterpart of the Tumor-Associated Antigen H-L6: Epitope Mapping of the Human and Murine L6 Antigens
Biochemistry, ISSN: 15204995 00062960
Caroline P. Edwards; Andrew G. Farr; John S. Marken; Andrew Nelson; Jürgen Bajorath; Karl Erik Hellstrom; Ingegerd Hellstrom; Alejandro Aruffo
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Anti-IgE therapy
Current Opinion in Immunology, ISSN: 09527915
Paula Jardieu
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Analysis of the Factor Vila Binding Site on Human Tissue Factor: Effects of Tissue Factor Mutations on the Kinetics and Thermodynamics of Binding
Biochemistry, ISSN: 15204995 00062960
Robert F. Kelley; Kimberly E. Costas; Mark P. O'Connell; Lazarus
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Structure-Based Design from Flexible Ligands
Annual Reports in Medicinal Chemistry, ISSN: 00657743
Robert S. McDowell; Dean R. Artis
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Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase
EMBO Journal, ISSN: 02614189
Yi-Li Yang; Luiz F. L. Reis; Jovan Paylovic; Sano Aguzzi; Reinhold Schäfer; Aseem Kumar; Bryan R. G. Williams; Michel Aguet; Charles Weissmann
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Dissection of the Extracellular Human Interferon γ Receptor α-Chain into two Immunoglobulin-like Domains. Production in an Escherichia coli Thioredoxin Gene Fusion Expression System and Recognition by Neutralizing Antibodies
Biochemistry, ISSN: 15204995 00062960
Geoffrey Williams; Nicole Ruegg; Ashley Birch; Christoph Weber; Klaus Hofstädter; John A. Robinson; Michel Aguet; Gianni Garotta; Daniel Schlatter; Walter Huber
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X-ray crystal structure analysis of the catalytic domain of the oncogene product p21H-ras complexed with caged GTP and mant dGppNHp
Journal of Molecular Biology, ISSN: 00222836
Axel J. Scheidig; Sybille M. Franken; John E.T. Corrie; Gordon P. Reid; Alfred Wittinghofer; Emil F. Pai; Roger S. Goody
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Novel inherited mutations and variable expressivity of BRCA1 alleles, including the founder mutation 185delAG in Ashkenazi Jewish families
American Journal of Human Genetics, ISSN: 00029297
Friedman; Szabo; Elizabeth A. Ostermeyer; Patrick Dowd; Lesley Butler; Tari Park; Ming K. Lee; Ellen L. Goode; Sarah E. Rowell; Mary-Claire King
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Aggressive behavior and altered amounts of brain serotonin and norepinephrine in mice lacking MAOA
Science, ISSN: 00368075
Olivier Cases; Isabelle Seif; Joseph Grimsby; Patricia Gaspar; Kevin Chen; Sandrine Pournin; Ulrike Müller; Michel Aguet; Charles Babinet; Jean Chen Shih; Edward De Maeyer
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Cloning of AL-1, a ligand for an Eph-related tyrosine kinase receptor involved in axon bundle formation
Neuron, ISSN: 08966273
Winslow; Paul Moran; Janet Valverde; Shih; Jean Q. Yuan; Suzy C. Wong; Siao Ping Tsai; Goddard; William J. Henzel; Franz Hefti; Klaus D. Beck; Caras
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The influence of heregulins on human Schwann cell proliferation
Journal of Neuroscience, ISSN: 02706474
Allan D. O. Levi; Richard P. Bunge; Julie A. Lofgren; Leonie Meima; Franz Hefti; Nikolics; Mark X. Sliwkowski
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Similar but nonidentical amino acid residues on vascular cell adhesion molecule-1 are involved in the interaction with α4β1 and α4β7 under different activity states
Journal of Immunology, ISSN: 00221767
Chiu; Crowe; Renz; Presta; Susan Jones; Irving L. Weissman; Sherman Fong
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Regulation by vascular endothelial growth factor of human colon cancer tumorigenesis in a mouse model of experimental liver metastasis
Journal of Clinical Investigation, ISSN: 00219738
Robert S. Warren; Hui Yuan; Mary R. Matli; Nancy Gillett; Napoleone Ferrara
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Structuraldeterminants of calcium signaling by RGD peptidesin rat osteoclasts: Integrin-dependent and -independent actions
Experimental Cell Research, ISSN: 00144827
Shankar; Thomas Gadek; Burdick; Ian Davison; Mason; Horton
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NGF receptor expression in sensory neurons develops normally in embryos lacking NGF
Developmental Biology, ISSN: 00121606
Alun M. Davies; Sean Wyatt; Merry Nishimura; Phillips
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Neutrophilia in mice that lack the murine IL-8 receptor homolog
Science, ISSN: 00368075
Shuster; Marcus E. Kehrli Jr.; Mark R. Ackermann; Mark Moore; Cacalano; William I. Wood; Edward Bailish
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Aequorea green fluorescent protein analysis by flow cytometry
Communications in Clinical Cytometry, ISSN: 10970320 01964763
J. Dezz Ropp; Christopher J. Donahue; David Wolfgang-Kimball; Jeff Hooley; James Y. W. Chin; Robert A. Hoffman; R. Andrew Cuthbertson; Kenneth D. Bauer
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Buffer exchange using size exclusion chromatography, countercurrent dialysis, and tangential flow filtration: Models, development, and industrial application
Biotechnology and Bioengineering, ISSN: 10970290 00063592
Ronald T. Kurnik; Audrey W. Yu; Gregory S. Blank; Arlene R. Burton; David Smith; Atul M. Athalye; Robert Van Reis
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Kidney as a major clearance organ for recombinant human interleukin‐1 receptor antagonist
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Dong‐Chool Kim; Barbara Reitz; David F. Carmichael; Duane C. Bloedow
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Truncated and Catalytic Isoforms of trkB are Co‐expressed in Neurons of Rat and Mouse CNS
European Journal of Neuroscience, ISSN: 14609568 0953816X
Armanini; McMahon; Sutherland; David L. Shelton; Phillips
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Adverse event data collection and reporting: A discussion of two grey areas
Therapeutic Innovation and Regulatory Science, ISSN: 21684804 21684790
Nickas
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Regional changes of ciliary neurotrophic factor and nerve growth factor levels in post mortem spinal cord and cerebral cortex from patients with motor disease
Nature Medicine, ISSN: 1546170X 10788956
Anand; Parrett; Martin; Zeman; Foley; Swash; Leigh; Jesse M. Cedarbaum; Lindsay; Williams-Chestnut; Sinicropi
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The biological effects of endogenous nerve growth factor on adult sensory neurons revealed by a trka-igg fusion molecule
Nature Medicine, ISSN: 1546170X 10788956
McMahon; David L. H. Bennett; John V. Priestley; David L. Shelton
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