Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 14451 - 14500 OF 15797 RESULTS

Characterization of the human 5-hydroxytryptamine(1B) receptor
Journal of Biological Chemistry, ISSN: 00219258
Hui Jin; Donna Oksenberg; Avi Ashkenazi; Peroutka; Alessandra M. V. Duncan; Richard Rozmahel; Yilli Yang; Mengod; Jose M. Palacios; Brian F. O'Dowd
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Dominant negative mutants of transforming growth factor-β1 inhibit the secretion of different transforming growth factor-β isoforms
Molecular and Cellular Biology, ISSN: 02707306
Alfredo R. Lopez; Cook; Prescott L. Deininger; Rik Derynck
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Expression of serum insulin-like growth factors, insulin-like growth factor-binding proteins, and the growth hormone-binding protein in heterozygote relatives of Ecuadorian growth hormone receptor deficient patients
Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X
Fielder; Jaime Guevara-Aguirret; Arlan L. Rosenbloom; Carlsson; Hintz; Rosenfeld
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Properties of spontaneous growth hormone secretory bursts and half-life of endogenous growth hormone in boys with idiopathic short stature. Genentech Collaborative Group
Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X
Johannes D. Veldhuis; Alan D. Rogol; Paul M. Martha Jr.; Ann J. Johanson; Robert M. Blizzard; Cara; James W. Frane; Gertner; Hintz; Chernausak; Nancy Hopwood; Selna Kaplan; Kirkland; Barbara M. Lippe; Leslie Plotnick; Saenger; Barry M. Sherman
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Homeodomain-independent activity of the fushi tarazu polypeptide in Drosophila embryos
Nature, ISSN: 00280836
V. Danial Fitzpatrick; Anthony Percival-Smith; C. James Ingles; Henry M. Krause
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Gonadotropin-releasing hormone, inhibin, and activin in human placenta: Evidence for a common cellular localization
Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X
Petraglia; Woodruff; Giovanna Botticelli; Annibale Botticelli; Andrea R. Genazzani; Kelly E. Mayo; Wylie Vale
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Diagnostic utility of DNA content flow cytometry in follicular neoplasms of the thyroid
Journal of Surgical Oncology, ISSN: 10969098 00224790
Harlow; Duda; Kenneth D. Bauer
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Identification of heregulin, a specific activator of p185erbB2
Science, ISSN: 00368075
William E. Holmes; Mark X. Sliwkowski; Robert W. Akita; William J. Henzel; James Lee; Park; Yansura; Nasrin Abadi; Helga Raab; Gail D. Lewis; Shepard; Wun-Jing Kuang; William I. Wood; David V. Goeddel; Richard L. Vandlen
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Multiple elements within the glucocorticoid regulatory unit of the rat α1-acid glycoprotein gene are recognition sites for C/EBP
Journal of Biological Chemistry, ISSN: 00219258
Thomas Ratajczak; Williams; Diego DiLorenzo; Gordon M. Ringold
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Molecular cloning and expression of the murine RANTES cytokine: structural and functional conservation between mouse and man
European Journal of Immunology, ISSN: 15214141 00142980
Thomas J. Schall; Simpson; John Mak
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Rational design of potent antagonists to the human growth hormone receptor
Science, ISSN: 00368075
Fuh; Cunningham; Rikiro Fukunaga; Shigekazu Nagata; David V. Goeddel; James A. Wells
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α-Isoenzyme of alcohol dehydrogenase from monkey liver. Cloning, expression, mechanism, coenzyme, and substrate specificity
Journal of Biological Chemistry, ISSN: 00219258
Light; Dennis; Ian J. Forsythe; Liu; Green; Darla Ann Kratzer; Bryce V. Plapp
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Neutralization of multiple laboratory and clinical isolates of human immunodeficiency virus type 1 (HIV-1) by antisera raised against gp120 from the MN isolate of HIV-1
Journal of Virology, ISSN: 0022538X
Berman; Matthews; Riddle; Mark Champe; Hobbs; Nakamura; Jennifer Mercer; Eastman; Catherine Lucas; Alphonse J. Langlois; Florian M. Wurm; Timothy Gregory
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Effects of recombinant human insulin-like growth factor-I (rhIGF-I) on total and free IGF-I concentrations, IGF-binding proteins, and glycemic response in humans
Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X
Steven A. Lieberman; Julie Bukar; Chen; Abbie Celniker; Peter G. Compton; Cook; Albu; Andrew J. Perlman; Andrew R. Hoffman
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Polyethylene glycol enhanced refolding of bovine carbonic anhydrase B. Reaction stoichiometry and refolding model
Journal of Biological Chemistry, ISSN: 00219258
Cleland; Hedgepeth; Daniel I. C. Wang
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An isoform of protein disulfide isomerase isolated from chronic myelogenous leukemia cells alters complex formation between nuclear proteins and regulatory regions of interferon-inducible genes
Journal of Biological Chemistry, ISSN: 00219258
Johnson; William J. Henzel; Albert Deisseroth
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Conformational Effects in the Reversed-Phase Chromatographic Behavior of Recombinant Human Growth Hormone (rhGH) and N-Methionyl Recombinant Human Growth Hormone (Met-hGH)
Analytical Chemistry, ISSN: 15206882 00032700
Peter Oroszlan; Wicar; Shiaw-Lin Wu; Karger; Glen Teshima; Wu; William S. Hancock
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Transcription and recombination of the murine RS element
Journal of Immunology, ISSN: 00221767
Loren E. Daitch; Mark Moore; Denise M. Persiani; Jeannine M. Durdik; Erik Selsing
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Editorial overview
Current Opinion in Structural Biology, ISSN: 0959440X
Raymond Salemme; James A. Wells
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Effects of recombinant insulin-like growth factor-I (IGF-I) and growth hormone on serum IGF-binding proteins in calorically restricted adults
Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X
Simon C. J. Young; Louis E. Underwood; Abbie Celniker; David R. Clemmons
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K‐252b Selectively Potentiates Cellular Actions and trk Tyrosine Phosphorylation Mediated by Neurotrophin‐3
Journal of Neurochemistry, ISSN: 14714159 00223042
Beat Knüsel; David R. Kaplan; Winslow; Rosenthal; Louis E. Burton; Klaus D. Beck; Stuart Rabin; Nikolics; Franz Hefti
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Altered metabolic and adhesive properties and increased tumorigenesis associated with increased expression of transforming growth factor β1
Journal of Cell Biology, ISSN: 00219525
Arrick; Alfredo R. Lopez; Fred Elfman; Reinhard Ebner; Caroline H. Damsky; Rik Derynck
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Variability of conformations at crystal contacts in BPTI represent true low‐energy structures: Correspondence among lattice packing and molecular dynamics structures
Proteins: Structure, Function and Bioinformatics, ISSN: 10970134 08873585
Anthony A. Kossiakoff; Michael Randal; Guenot; Charles Eignebrot
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Structural consequences of mutation
Current Opinion in Biotechnology, ISSN: 09581669
Eigenbrot; Anthony A. Kossiakoff
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Characterization of two high affinity human interleukin-8 receptors
Journal of Biological Chemistry, ISSN: 00219258
James Lee; Richard Horuk; Glenn C. Rice; Bennett; Camerato; William I. Wood
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The effect of anorexia nervosa and refeeding on growth hormone-binding protein, the insulin-like growth factors (IGFs), and the IGF-binding proteins
Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X
Debra R. Counts; Harry Gwirtsman; Carlsson; Michael Lesem
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Signal transduction by the platelet integrin αiibβ3: Induction of calcium oscillations required for protein-tyrosine phosphorylation and ligand-induced spreading of stably transfected cells
Molecular Biology of the Cell, ISSN: 10591524
Pelletier; Bodary; Levinson
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Activin-a inhibits progesterone production by macaque luteal cells in culture
Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X
John D. Brannian; Woodruff; Mather; Richard L. Stouffer
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Loss of gene function through rapid mitotic cycles in the Drosophila embryo
Nature, ISSN: 00280836
Mike Rothe; Michael Pehl; Heike Taubert; Herbert Jäckle
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In vitro inhibitory effect of IL-8 and other chemoattractants on neutrophil-endothelial adhesive interactions
Journal of Immunology, ISSN: 00221767
Francis W. Luscinskas; Jeanne-Marie Kiely; Han Ding; Obin; Hébert; Baker; Gimbrone Jr.
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Modulation of airway inflammation in cystic fibrosis: In vivo suppression of interleukin-8 levels on the respiratory epithelial surface by aerosolization of recombinant secretory leukoprotease inhibitor
Journal of Clinical Investigation, ISSN: 00219738
McElvaney; Nakamura; Birrer; Hébert; Wai Lee T. Wong; Merlyn Alphonso; Baker; Catalano; Crystal
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Identification of an E-selectin region critical for carbohydrate recognition and cell adhesion
Journal of Cell Biology, ISSN: 00219525
David V. Erbe; Barry A. Wolitzky; Presta; Norton; Robert J. Ramos; Daniel K. Burns; John M. Rumberger; B. N. Narasinga Rao; Carroll Foxall; Brian K. Brandley; Lasky
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Comparative Study of Photodissociation and Surface-Induced Dissociation by Laser Desorption Fourier Transform Mass Spectrometry
Analytical Chemistry, ISSN: 15206882 00032700
John A. Castoro; Charles L. Wilkins; Lydia M. Nuwaysir; Carl F. Ijames
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Treatment of systemic sclerosis with recombinant interferon‐γ. A phase I/II clinical trial
Arthritis and Rheumatism, ISSN: 15290131 00043591
Bruce Freundlich; Sergio A. Jimenez; Virginia D. Steen; Thomas A. Medsger Jr.; Michelle Szkolnicki; Howard S. Jaffe
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Prohormone convertase-1 will process prorelaxin, a member of the insulin family of hormones
Molecular Endocrinology, ISSN: 19449917 08888809
David Marriott; Beth Gillece-Castro; Cornelia M. Gorman
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A GDP dissociation inhibitor that serves as a GTPase inhibitor for the Ras-like protein CDC42Hs
Science, ISSN: 00368075
Matthew J. Hart; Yoshiro Maru; Leonard; Owen N. Witte; Tony Evans; Richard A. Cerione
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Biochemical Characterization of Recombinant Human Nerve Growth Factor
Journal of Neurochemistry, ISSN: 14714159 00223042
Charles H. Schmelzer; Louis E. Burton; Wai-Pan Chan; Evelyn Martin; Cornelia M. Gorman; Eleanor Canova-Davis; Victor Ling; Mary B. Sliwkowski; Glynis McCray; Jonathan A. Briggs; Tue H. Nguyen; Gian D. Polastri
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Identification of actin and HSP 70 as cyclosporin A binding proteins by photoaffinity labeling and fluorescence displacement assays
Journal of Biological Chemistry, ISSN: 00219258
Marcia L. Moss; Palmer; Petr Kuzmič; Brian E. Dunlap; William J. Henzel; James L. Kofron; William S. Mellon; Catherine A. Royer; Daniel H. Rich
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A single amino-acid difference confers major pharmacological variation between human and rodent 5-HT1B receptors
Nature, ISSN: 00280836
Donna Oksenberg; Scot A. Marsters; Brian F. O'Dowd; Hui Jin; Sona Havlik; Peroutka; Avi Ashkenazi
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The amino terminus of nerve growth factor is involved in the interaction with the receptor tyrosine kinase p140(trkA)
Journal of Biological Chemistry, ISSN: 00219258
Philipp Kahle; Louis E. Burton; Charles H. Schmelzer; Cornelia Hertel
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Quadruplex structure of d(G3T4G3) stabilized by K+ or Na+ is an asymmetric hairpin dimer
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Scaria; Steven J. Shire; Richard H. Shafer
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Random PCR mutagenesis screening of secreted proteins by direct expression in mammalian cells
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Glenn C. Rice; David V. Goeddel; Cachianes; John D. Woronicz; Ellson Y. Chen; Steven R. Williams; Leung
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Involvement of endogenous tumor necrosis factor α and transforming growth factor β during induction of collagen type II arthritis in mice
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Thorbecke; Shah; Chin-Hung Leu; Kuruvilla; Hardison; Michael A. Palladino
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Isolation and characterization of two safflower oleoyl-acyl carrier protein thioesterase cDNA clones
Plant Physiology, ISSN: 00320889
Deborah S. Knutzon; Janice L. Bleibaum; Janet Nelsen; Jean C. Kridl; Gregory A. Thompson
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The vascular endothelial growth factor proteins: Identification of biologically relevant regions by neutralizing monoclonal antibodies
Growth Factors, ISSN: 08977194
K.Jin Kim; Bing Li; Houck; Jane Winer; Napoleone Ferrara
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Binding sites for vascular endothelial growth factor are localized on endothelial cells in adult rat tissues
Journal of Clinical Investigation, ISSN: 00219738
Lyn B. Jakeman; Jane Winer; Bennett; Anthony Altar; Napoleone Ferrara
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Peptide mapping for detecting variants in protein products.
Developments in biological standardization, ISSN: 03015149
Robert L. Garnick
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Involvement of zinc in binding of hGH to the prolactin receptor
Biomedicine and Pharmacotherapy, ISSN: 07533322
Wells
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Crystal Structure of the Kringle 2 Domain of Tissue Plasminogen Activator at 2.4-Å. Resolution
Biochemistry, ISSN: 15204995 00062960
De Vos; Ultsch; Robert F. Kelley; Anthony A. Kossiakoff; Kaillathe Padmanabhan; Alexander Tulinsky; Mary L. Westbrook
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Assignment of the Aliphatic 1H and 13C Resonances of the Bacillus Subtilis Glucose Permease IIA Domain Using Double- and Triple-Resonance Heteronuclear Three-Dimensional NMR Spectroscopy
Biochemistry, ISSN: 15204995 00062960
Mark Ranee; Peter E. Wright; Wayne J. Fairbrother; Arthur G. Palmer III; Jonathan Reizer; Milton H. Saier Jr.
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