Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 3201 - 3250 OF 16362 RESULTS

Ubiquitination in the regulation of inflammatory cell death and cancer
Cell Death and Differentiation, ISSN: 14765403 13509047
Peter E. Cockram; Matthias Kist; Sumit Prakash; Si-Han Chen; Ingrid E. Wertz; Domagoj Vucic
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Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma
Nature Medicine, ISSN: 1546170X 10788956
Livnat Jerby-Arnon; Cyril Neftel; Marni E. Shore; Hannah R. Weisman; Nathan D. Mathewson; Matthew J. McBride; Brian Haas; Benjamin Izar; Angela Volorio; Gaylor Boulay; Luisa Cironi; Alyssa R. Richman; Liliane C. Broye; Joseph M. Gurski; Christina C. Luo; Ravindra Mylvaganam; Lan Nguyen; Shaolin Mei; Johannes C. Melms; Christophe Georgescu; Ofir Cohen; Jorge E. Buendia-Buendia; Asa Segerstolpe; Malika Sud; Michael S. Cuoco; Danny Labes; Simon Gritsch; Daniel R. Zollinger; Nicole Ortogero; Joseph M. Beechem; Petur Nielsen; Ivan Chebib; Tu Nguyen-Ngoc; Michael Montemurro; Gregory M. Cote; Edwin Choy; Igor Letovanec; Stéphane Cherix; Nikhil Wagle; Peter K. Sorger; Alex B. Haynes; John T. Mullen; Ivan Stamenkovic; Miguel N. Rivera; Cigall Kadoch; Kai W. Wucherpfennig; Orit Rozenblatt-Rosen; Mario L. Suvà; Nicolò Riggi; Aviv Regev
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Gut CD4+ T cell phenotypes are a continuum molded by microbes, not by TH archetypes
Nature Immunology, ISSN: 15292916 15292908
Elijah Willie; Hugo Schmutz; Jodie Chandler; Alexandra Schnell; Pratiksha I. Thakore; Graham LeGros; Sara Mostafavi; Mathis; Christophe Benoist; Oscar Aguilar; Rhys Allan; Jillian L. Astarita; K Frank Austen; Nora A. Barrett; Alev Baysoy; Christophe Benoist; Brian Brown; Matthew B. Buechler; Jason D. Buenrostro; Maria Acebes Casanova; Kyunghee Choi; Kaitavjeet Chowdhary; Marco Colonna; Ty Crowl; Tianda Deng; Jigar V. Desai; Fiona Desland; Maxime Dhainaut; Jiarui Ding; Claudia X. Dominguez; Daniel F. Dwyer; Michela Frascoli; Shani Gal-Oz; Ananda Goldrath; Ricardo Grieshaber-Bouyer; Baosen Jia; Tim Johanson; Stefan Jordan; Joonsoo Kang; Varun N. Kapoor; Ephriam Kenigsberg; Joel Kim; Ki wook Kim; Evgeny Kiner; Mitchell Kronenberg; Lewis L. Lanier; Catherine Laplace; Caleb A. Lareau; Andrew Leader; Jisu Lee; Assaf Magen; Barbara Maier; Alexandra Maslova; Diane Mathis; Adelle McFarland; Miriam Merad; Etienne Meunier; Monach; Sara Mostafavi; Sören Müller; Christoph Muus; Hadas Ner-Gaon; Quyhn Nguyen; Peter A. Nigrovic; German Novakovsky; Stephen L. Nutt; Kayla Omilusik; Adriana Ortiz-Lopez; Mallory Paynich; Vincent Peng; Marc Potempa; Rachana Pradhan; Sara Quon; Ricardo N. Ramirez; Deepshika Ramanan; Gwendalyn J. Randolph; Aviv Regev; Samuel A. Rose; Kumba Seddu; Tal Shay; Avishai Shemesh; Justin A. Shyer; Christopher Smilie; Nick Spidale; Ayshwarya Subramanian; Katelyn Sylvia; Julie Tellier; Shannon J. Turley; Brinda Vijaykumar; Amy Wagers; Chendi Wang; Peter L. Wang; Aleksandra Wroblewska; Liang Yang; Aldrin Yim; Hideyuki Yoshida
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Few-shot learning creates predictive models of drug response that translate from high-throughput screens to individual patients
Nature Cancer, ISSN: 26621347
Jianzhu Ma; Samson H. Fong; Yunan Luo; Christopher J. Bakkenist; John Paul Shen; Soufiane Mourragui; Lodewyk F. A. Wessels; Marc Hafner; Roded Sharan; Jian Peng; Trey Ideker
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An anti–CD22-seco-CBI-dimer antibody–drug conjugate (ADC) for the treatment of non-hodgkin lymphoma that provides a longer duration of response than auristatin-based ADCs in preclinical models
Molecular Cancer Therapeutics, ISSN: 15388514 15357163
Shang-Fan Yu; Donna W. Lee; Bing Zheng; Geoffrey Del Rosario; Douglas Leipold; Helen Booler; Fiona Zhong; Montserrat Carrasco-Triguero; Kyu Hong; Peter Yan; Rebecca K. Rowntree; Melissa Schutten; Thomas H. Pillow; Jack D. Sadowsky; Peter Dragovich; Andrew G. Polson
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NRF2 Activation promotes aggressive lung cancer and associates with poor clinical outcomes
Clinical Cancer Research, ISSN: 15573265 10780432
Anju Singh; Anneleen Daemen; Dorothee Nickles; Sang-Min Jeon; Oded Foreman; Kuladeep Sudini; Florian Gnad; Stephane Lajoie; Naina Gour; Wayne Mitzner; Samit Chatterjee; Eun-Ji Choi; Buvana Ravishankar; Amy Rappaport; Namrata S. Patil; Mark L. McCleland; Leisa Johnson; George Acquaah-Mensah; Edward Gabrielson; Shyam Biswal; Georgia Hatzivassiliou
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Improving cryo-EM structure validation
Nature Methods, ISSN: 15487105
Alexis Rohou
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An expanded analysis framework for multivariate GWAS connects inflammatory biomarkers to functional variants and disease
European Journal of Human Genetics, ISSN: 14765438 10184813
Sanni E. Ruotsalainen; Juulia J. Partanen; Anna Cichonska; Jake Lin; Christian Benner; Ida Surakka; Mark J. Daly; Howard Jacob; Sally John; Robert M. Plenge; Mark I. McCarthy; Caroline Fox; Kathy Call; Tomi P. Mäkelä; Jaakko Kaprio; Petri Virolainen; Kari Pulkki; Terhi Kilpi; Anne Pitkäranta; Riitta Kaarteenaho; Urho Kujala; Jimmy Liu; Shameek Biswas; Meg Ehm; Caroline S. Fox; Anders Mälarstig; Catherine Marshall; Xinli Hu; Kathy Klinger; Matthias Gossel; Johanna Schleutker; Markus Perola; Mikko Arvas; Olli Carpen; Reetta Hinttala; Reijo Laaksonen; Arto Mannermaa; Juha Paloneva; Outi Tuovila; Minna Hendolin; Raimo Pakkanen; Hilkka Soininen; Valtteri Julkunen; Anne Remes; Reetta Kälviäinen; Mikko Hiltunen; Jukka Peltola; Pentti Tienari; Juha Rinne; Adam Ziemann; Sahar Esmaeeli; Susan Eaton; Sanni Lahdenperä; Geoffrey A. Kerchner; Natalie Bowers; Edmond Teng; John Eicher; Vinay Mehta; Padhraig Gormley; Kari Linden; Christopher D. Whelan; Fanli Xu; David Pulford; Martti Färkkilä; Sampsa Pikkarainen; Airi Jussila; Timo Blomster; Mikko Kiviniemi; Markku Voutilainen; Graham Heap; Keith Usiskin; Tim Lu; Danny Oh; Vinay Mehta; Melissa Miller; Xinli Hu; Linda McCarthy; Kari Eklund; Antti Palomäki; Pia Isomäki; Laura Pirilä; Oili Kaipiainen-Seppänen; Johanna Huhtakangas; Bob Georgantas; Apinya Lertratanakul; Marla Hochfeld; Vinay Mehta; Nan Bing; Xinli Hu; Jorge Esparza Gordillo; Nina Mars; Margit Pelkonen; Paula Kauppi; Hannu Kankaanranta; Terttu Harju; David Close; Steven Greenberg; Hubert Chen; Vinay Mehta; Jo Betts; Soumitra Ghosh; Veikko Salomaa; Teemu Niiranen; Markus Juonala; Kaj Metsärinne; Mika Kähönen; Juhani Junttila; Markku Laakso; Jussi Pihlajamäki; Juha Sinisalo; Marja-Riitta Taskinen; Tiinamaija Tuomi; Jari Laukkanen; Ben Challis; Andrew S. Peterson; Audrey Y. Chu; Vinay Mehta; Jaakko Parkkinen; Melissa Miller; Anthony Muslin; Heikki Joensuu; Tuomo Meretoja; Lauri Aaltonen; Annika Auranen; Peeter Karihtala; Saila Kauppila; Päivi Auvinen; Elenius; Relja Popovic; Jeff Waring; Athena Matakidou; Jennifer L. Schutzman; Vinay Mehta; Andrey Loboda; Aparna Chhibber; Heli Lehtonen; Stefan McDonough; Marika Crohns; Diptee Kulkarni; Kai Kaarniranta; Joni A. Turunen; Terhi Ollila; Sanna Seitsonen; Hannu Uusitalo; Vesa Aaltonen; Hannele Uusitalo-Järvinen; Marja Luodonpää; Nina Hautala; Heiko Runz; Erich C. Strauss; Hao Chen; Anna Podgornaia; Vinay Mehta; Joshua Hoffman; Kaisa Tasanen; Laura Huilaja; Katariina Hannula-Jouppi; Teea Salmi; Sirkku Peltonen; Leena Koulu; Ilkka Harvima; Kirsi Kalpala; Ying Wu; David Choy; John Michon; Nizar Smaoui; Fedik Rahimov; Anne Lehtonen; Dawn Waterworth; Risto Kajanne; Ulrike Lyhs; Mari Kaunisto; Justin Wade Davis; Bridget Riley-Gillis; Danjuma Quarless; Slavé Petrovski; Jimmy Liu; Chia-Yen Chen; Paola G. Bronson; Robert Yang; Joseph Maranville; Diana Chang; Julie Hunkapiller; Tushar Bhangale; Dorothée Diogo; Emily Holzinger; Padhraig Gormley; Xulong Wang; Xing Chen; Åsa Hedman; Kirsi Auro; Clarence Wang; Ethan Xu; Franck Auge; Clement Chatelain; Mitja Kurki; Mark Daly; Juha Karjalainen; Aki S. Havulinna; Anu Jalanko; Kimmo Palin; Pietro della Briotta Parolo; Wei Zhou; Manuel Rivas; Aarno Palotie; Arto Lehisto; Andrea Ganna; Vincent Llorens; Antti Karlsson; Kati Hyvärinen; Jarmo Ritari; Tiina Wahlfors; Miika Koskinen; Johannes Kettunen; Katri Pylkäs; Marita Kalaoja; Minna Karjalainen; Tuomo Mantere; Eeva Kangasniemi; Sami Heikkinen; Arto Mannermaa; Eija Laakkonen; Juha Kononen; Anu Loukola; Päivi Laiho; Tuuli Sistonen; Essi Kaiharju; Markku Laukkanen; Elina Järvensivu; Sini Lähteenmäki; Lotta Männikkö; Regis Wong; Kati Kristiansson; Hannele Mattsson; Tero Hiekkalinna; Manuel González Jiménez; Kati Donner; Kalle Pärn; Javier Nunez-Fontarnau; Jarmo Harju; Elina Kilpeläinen; Georg Brein; Alexander Dada; Ghazal Awaisa; Anastasia Shcherban; Timo P. Sipilä; Hannele Laivuori; Susanna Lemmelä; Tuomo T. J. Kiiskinen; Tarja Laitinen; Harri Siirtola; Javier Gracia Tabuenca; Lila Kallio; Sirpa Soini; Jukka Partanen; Kimmo Pitkänen; Seppo Vainio; Kimmo Savinainen; Veli-Matti Kosma; Teijo Kuopio; Mary Pat Reeve; Priit Palta; Marko Salmi; Sirpa Jalkanen; Ari Ahola-Olli; Aarno Palotie; Veikko Salomaa; Mark Daly; Matti Pirinen; Samuli Ripatti; Jukka Koskela
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Phase 2 trial to assess lebrikizumab in patients with idiopathic pulmonary fibrosis
European Respiratory Journal, ISSN: 13993003 09031936
Toby M. Maher; Ulrich Costabel; Marilyn K Glassberg; Yasuhiro Kondoh; Takashi Ogura; Mary Beth Scholand; David Kardatzke; Monet Howard; Julie Olsson; Margaret Neighbors; Paula Belloni; Jeffrey J. Swigris
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2020 White Paper on Recent Issues in Bioanalysis: BMV of Hybrid Assays, Acoustic MS, HRMS, Data Integrity, Endogenous Compounds, Microsampling and Microbiome (Part 1 - Recommendations on Industry/Regulators Consensus on BMV of Biotherapeutics by LCMS, Advanced Application in Hybrid Assays, Regulatory Challenges in Mass Spec, Innovation in Small Molecules, Peptides and Oligos)
Bioanalysis, ISSN: 17576199 17576180
Hendrik Neubert; Stephen C. Alley; Anita Lee; Wenying Jian; Michael H. Buonarati; Anna Edmison; Fabio Garofolo; Boris Gorovits; Sam Haidar; Bill Mylott; Parya Nouri; Mark Qian; Stephen Vinter; Voelker; Jan Welink; Jiang Wu; Eric Yang; Hongbin Yu; Christopher Evans; Scott Summerfield; Jian Wang; Kevin Bateman; Jason Boer; Brian J. Dean; Lieve Dillen; Patrick Faustino; Luca Ferrari; Nicola Hughes; Lina Luo; Timothy Olah; Noah Post; Spellman; Jens Sydor; Hui Zhang; Jenny Zhang; Jinhui Zhang; Christine Fandozzi; Amanda Wilson; Daniela Fraier; Chris Beaver; Suman Dandamudi; Arindam Dasgupta; Rebecca Elliott; Allena Ji; Wenkui Li; Michael McGuinness; Gustavo Mendes Lima Santos; Tahseen Mirza; Natasha Savoie; Diaa Shakleya; Sune Sporring; Susan Stojdl; Phillip Sundman; Nilufer Tampal; Eric Woolf
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Characterization of robust immune responses to a bispecific antibody, a novel class of antibody therapeutics
Bioanalysis, ISSN: 17576199 17576180
Kun Peng; Ketevan A. Siradze; Saloumeh Kadkhodayan Fischer
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Extracellular BMP1 is the major proteinase for COOH-terminal proteolysis of type I procollagen in lung fibroblasts
American Journal of Physiology - Cell Physiology, ISSN: 15221563 03636143
Elsa-Noah N’Diaye; Ryan Cook; Hua Wang; Ping Wu; Ryan LaCanna; Cong Wu; Zhengmao Ye; Dhaya Seshasayee; Meredith Hazen; Wei Yu Lin; Tulika Tyagi; Isidro Hötzel; Lucinda Tam; Robert J. Newman; Merone Roose-Girma; Paul J. Wolters; Ning Ding
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Impact of delayed time to treatment on visual outcomes in neovascular AMD: Data from the harbor study
Ophthalmic Surgery Lasers and Imaging Retina, ISSN: 23258179 23258160
Roger A. Goldberg; Lauren Hill; Tatiana Davis; Carlos Quezada Ruiz
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Randomized Trial of Irinotecan and Cetuximab With or Without Vemurafenib in BRAF-Mutant Metastatic Colorectal Cancer (SWOG S1406)
Journal of Clinical Oncology, ISSN: 15277755
Scott Kopetz; Katherine A. Guthrie; Van Morris; Heinz-Josef Lenz; Anthony Magliocco; Dipen Maru; Yibing Yan; Richard Lanman; Ganiraju Manyam; David Hong; Alexey V. Sorokin; Chloe E. Atreya; Luis A. Diaz; Carmen Allegra; Kanwal Pratap Singh Raghav; Stephen E. Wang; Christopher H. Lieu; Shannon L. McDonough; Philip A. Philip; Hochster
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Consensus Guidelines: Best Practices for Detection, Assessment and Management of Suspected Acute Drug-Induced Liver Injury During Clinical Trials in Adults with Chronic Viral Hepatitis and Adults with Cirrhosis Secondary to Hepatitis B, C and Nonalcoholic Steatohepatitis
Drug Safety, ISSN: 11791942 01145916
William R. Treem; Melissa Palmer; Isabelle Lonjon-Domanec; Daniel W. Seekins; Lara Dimick-Santos; Mark I. Avigan; John F. Marcinak; Ajit Dash; Arie Regev; Eric S. Maller; Meenal Patwardhan; James H. Lewis; Don C. Rockey; Adrian M. Di Bisceglie; James W. Freston; Raúl J. Andrade; Naga P. Chalasani
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Gut CD4+ T cell phenotypes are a continuum molded by microbes, not by TH archetypes
Nature Immunology, ISSN: 15292916 15292908
Elijah Willie; Hugo Schmutz; Jodie Chandler; Alexandra Schnell; Pratiksha I. Thakore; Graham LeGros; Sara Mostafavi; Mathis; Christophe Benoist; Oscar Aguilar; Rhys Allan; Jillian L. Astarita; K Frank Austen; Nora A. Barrett; Alev Baysoy; Christophe Benoist; Brian Brown; Matthew B. Buechler; Jason D. Buenrostro; Maria Acebes Casanova; Kyunghee Choi; Kaitavjeet Chowdhary; Marco Colonna; Ty Crowl; Tianda Deng; Jigar V. Desai; Fiona Desland; Maxime Dhainaut; Jiarui Ding; Claudia X. Dominguez; Daniel F. Dwyer; Michela Frascoli; Shani Gal-Oz; Ananda Goldrath; Ricardo Grieshaber-Bouyer; Baosen Jia; Tim Johanson; Stefan Jordan; Joonsoo Kang; Varun N. Kapoor; Ephriam Kenigsberg; Joel Kim; Ki wook Kim; Evgeny Kiner; Mitchell Kronenberg; Lewis L. Lanier; Catherine Laplace; Caleb A. Lareau; Andrew Leader; Jisu Lee; Assaf Magen; Barbara Maier; Alexandra Maslova; Diane Mathis; Adelle McFarland; Miriam Merad; Etienne Meunier; Monach; Sören Müller; Christoph Muus; Hadas Ner-Gaon; Quyhn Nguyen; Peter A. Nigrovic; German Novakovsky; Stephen L. Nutt; Kayla Omilusik; Adriana Ortiz-Lopez; Mallory Paynich; Vincent Peng; Marc Potempa; Rachana Pradhan; Sara Quon; Ricardo N. Ramirez; Deepshika Ramanan; Gwendalyn J. Randolph; Aviv Regev; Samuel A. Rose; Kumba Seddu; Tal Shay; Avishai Shemesh; Justin A. Shyer; Christopher Smilie; Nick Spidale; Ayshwarya Subramanian; Katelyn Sylvia; Julie Tellier; Shannon J. Turley; Brinda Vijaykumar; Amy Wagers; Chendi Wang; Peter L. Wang; Aleksandra Wroblewska; Liang Yang; Aldrin Yim; Hideyuki Yoshida
View on Scopus
An expanded analysis framework for multivariate GWAS connects inflammatory biomarkers to functional variants and disease
European Journal of Human Genetics, ISSN: 14765438 10184813
Sanni E. Ruotsalainen; Juulia J. Partanen; Anna Cichonska; Jake Lin; Christian Benner; Ida Surakka; Howard Jacob; Sally John; Robert M. Plenge; Mark I. McCarthy; Caroline Fox; Kathy Call; Tomi P. Mäkelä; Jaakko Kaprio; Petri Virolainen; Kari Pulkki; Terhi Kilpi; Anne Pitkäranta; Riitta Kaarteenaho; Urho Kujala; Jimmy Liu; Shameek Biswas; Meg Ehm; Caroline S. Fox; Anders Mälarstig; Catherine Marshall; Xinli Hu; Kathy Klinger; Matthias Gossel; Johanna Schleutker; Markus Perola; Mikko Arvas; Olli Carpen; Reetta Hinttala; Reijo Laaksonen; Arto Mannermaa; Juha Paloneva; Outi Tuovila; Minna Hendolin; Raimo Pakkanen; Hilkka Soininen; Valtteri Julkunen; Anne Remes; Reetta Kälviäinen; Mikko Hiltunen; Jukka Peltola; Pentti Tienari; Juha Rinne; Adam Ziemann; Sahar Esmaeeli; Susan Eaton; Sanni Lahdenperä; Geoffrey A. Kerchner; Natalie Bowers; Edmond Teng; John Eicher; Padhraig Gormley; Kari Linden; Christopher D. Whelan; Fanli Xu; David Pulford; Martti Färkkilä; Sampsa Pikkarainen; Airi Jussila; Timo Blomster; Mikko Kiviniemi; Markku Voutilainen; Graham Heap; Keith Usiskin; Tim Lu; Danny Oh; Melissa Miller; Xinli Hu; Linda McCarthy; Kari Eklund; Antti Palomäki; Pia Isomäki; Laura Pirilä; Oili Kaipiainen-Seppänen; Johanna Huhtakangas; Bob Georgantas; Apinya Lertratanakul; Marla Hochfeld; Nan Bing; Xinli Hu; Jorge Esparza Gordillo; Nina Mars; Margit Pelkonen; Paula Kauppi; Hannu Kankaanranta; Terttu Harju; David Close; Steven Greenberg; Hubert Chen; Jo Betts; Soumitra Ghosh; Veikko Salomaa; Teemu Niiranen; Markus Juonala; Kaj Metsärinne; Mika Kähönen; Juhani Junttila; Markku Laakso; Jussi Pihlajamäki; Juha Sinisalo; Marja-Riitta Taskinen; Tiinamaija Tuomi; Jari Laukkanen; Ben Challis; Andrew S. Peterson; Audrey Y. Chu; Jaakko Parkkinen; Melissa Miller; Anthony Muslin; Heikki Joensuu; Tuomo Meretoja; Lauri Aaltonen; Annika Auranen; Peeter Karihtala; Saila Kauppila; Päivi Auvinen; Elenius; Relja Popovic; Jeff Waring; Athena Matakidou; Jennifer L. Schutzman; Andrey Loboda; Aparna Chhibber; Heli Lehtonen; Stefan McDonough; Marika Crohns; Diptee Kulkarni; Kai Kaarniranta; Joni A. Turunen; Terhi Ollila; Sanna Seitsonen; Hannu Uusitalo; Vesa Aaltonen; Hannele Uusitalo-Järvinen; Marja Luodonpää; Nina Hautala; Heiko Runz; Erich C. Strauss; Hao Chen; Anna Podgornaia; Vinay Mehta; Joshua Hoffman; Kaisa Tasanen; Laura Huilaja; Katariina Hannula-Jouppi; Teea Salmi; Sirkku Peltonen; Leena Koulu; Ilkka Harvima; Kirsi Kalpala; Ying Wu; David Choy; John Michon; Nizar Smaoui; Fedik Rahimov; Anne Lehtonen; Dawn Waterworth; Risto Kajanne; Ulrike Lyhs; Mari Kaunisto; Justin Wade Davis; Bridget Riley-Gillis; Danjuma Quarless; Slavé Petrovski; Jimmy Liu; Chia-Yen Chen; Paola G. Bronson; Robert Yang; Joseph Maranville; Diana Chang; Julie Hunkapiller; Tushar Bhangale; Dorothée Diogo; Emily Holzinger; Padhraig Gormley; Xulong Wang; Xing Chen; Åsa Hedman; Kirsi Auro; Clarence Wang; Ethan Xu; Franck Auge; Clement Chatelain; Mitja Kurki; Juha Karjalainen; Aki S. Havulinna; Anu Jalanko; Kimmo Palin; Pietro della Briotta Parolo; Wei Zhou; Manuel Rivas; Aarno Palotie; Arto Lehisto; Andrea Ganna; Vincent Llorens; Antti Karlsson; Kati Hyvärinen; Jarmo Ritari; Tiina Wahlfors; Miika Koskinen; Johannes Kettunen; Katri Pylkäs; Marita Kalaoja; Minna Karjalainen; Tuomo Mantere; Eeva Kangasniemi; Sami Heikkinen; Arto Mannermaa; Eija Laakkonen; Juha Kononen; Anu Loukola; Päivi Laiho; Tuuli Sistonen; Essi Kaiharju; Markku Laukkanen; Elina Järvensivu; Sini Lähteenmäki; Lotta Männikkö; Regis Wong; Kati Kristiansson; Hannele Mattsson; Tero Hiekkalinna; Manuel González Jiménez; Kati Donner; Kalle Pärn; Javier Nunez-Fontarnau; Jarmo Harju; Elina Kilpeläinen; Georg Brein; Alexander Dada; Ghazal Awaisa; Anastasia Shcherban; Timo P. Sipilä; Hannele Laivuori; Susanna Lemmelä; Tuomo T. J. Kiiskinen; Tarja Laitinen; Harri Siirtola; Javier Gracia Tabuenca; Lila Kallio; Sirpa Soini; Jukka Partanen; Kimmo Pitkänen; Seppo Vainio; Kimmo Savinainen; Veli-Matti Kosma; Teijo Kuopio; Mary Pat Reeve; Priit Palta; Marko Salmi; Sirpa Jalkanen; Ari Ahola-Olli; Aarno Palotie; Veikko Salomaa; Mark J. Daly; Matti Pirinen; Samuli Ripatti; Jukka Koskela
View on Scopus
Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma
Nature Medicine, ISSN: 1546170X 10788956
Livnat Jerby-Arnon; Cyril Neftel; Marni E. Shore; Hannah R. Weisman; Nathan D. Mathewson; Matthew J. McBride; Brian Haas; Benjamin Izar; Angela Volorio; Gaylor Boulay; Luisa Cironi; Alyssa R. Richman; Liliane C. Broye; Joseph M. Gurski; Christina C. Luo; Ravindra Mylvaganam; Lan Nguyen; Shaolin Mei; Johannes C. Melms; Christophe Georgescu; Ofir Cohen; Jorge E. Buendia-Buendia; Asa Segerstolpe; Malika Sud; Michael S. Cuoco; Danny Labes; Simon Gritsch; Daniel R. Zollinger; Nicole Ortogero; Joseph M. Beechem; Petur Nielsen; Ivan Chebib; Tu Nguyen-Ngoc; Michael Montemurro; Gregory M. Cote; Edwin Choy; Igor Letovanec; Stéphane Cherix; Nikhil Wagle; Peter K. Sorger; Alex B. Haynes; John T. Mullen; Ivan Stamenkovic; Miguel N. Rivera; Cigall Kadoch; Kai Wucherpfennig; Orit Rozenblatt-Rosen; Mario L. Suvà; Nicolò Riggi; Aviv Regev
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Neurodegeneration, gliosis, and resolution of haemorrhage in neovascular age-related macular degeneration, a clinicopathologic correlation
Eye, ISSN: 14765454 0950222X
Miaoling Li; Rosa Dolz-Marco; Jeffrey D. Messinger; Daniela Ferrara; K. Bailey Freund; Christine A. Curcio
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An expanded analysis framework for multivariate GWAS connects inflammatory biomarkers to functional variants and disease
European Journal of Human Genetics, ISSN: 14765438 10184813
Sanni E. Ruotsalainen; Juulia J. Partanen; Anna Cichonska; Jake Lin; Christian Benner; Ida Surakka; Howard Jacob; Sally John; Robert M. Plenge; Mark I. McCarthy; Caroline Fox; Kathy Call; Tomi P. Mäkelä; Jaakko Kaprio; Petri Virolainen; Kari Pulkki; Terhi Kilpi; Anne Pitkäranta; Riitta Kaarteenaho; Urho Kujala; Jimmy Liu; Shameek Biswas; Meg Ehm; Caroline S. Fox; Anders Mälarstig; Catherine Marshall; Xinli Hu; Kathy Klinger; Matthias Gossel; Johanna Schleutker; Markus Perola; Mikko Arvas; Olli Carpen; Reetta Hinttala; Reijo Laaksonen; Arto Mannermaa; Juha Paloneva; Outi Tuovila; Minna Hendolin; Raimo Pakkanen; Hilkka Soininen; Valtteri Julkunen; Anne Remes; Reetta Kälviäinen; Mikko Hiltunen; Jukka Peltola; Pentti Tienari; Juha Rinne; Adam Ziemann; Sahar Esmaeeli; Susan Eaton; Sanni Lahdenperä; Geoffrey A. Kerchner; Natalie Bowers; Edmond Teng; John Eicher; Padhraig Gormley; Kari Linden; Christopher D. Whelan; Fanli Xu; David Pulford; Martti Färkkilä; Sampsa Pikkarainen; Airi Jussila; Timo Blomster; Mikko Kiviniemi; Markku Voutilainen; Graham Heap; Keith Usiskin; Tim Lu; Danny Oh; Xinli Hu; Linda McCarthy; Kari Eklund; Antti Palomäki; Pia Isomäki; Laura Pirilä; Oili Kaipiainen-Seppänen; Johanna Huhtakangas; Bob Georgantas; Apinya Lertratanakul; Marla Hochfeld; Nan Bing; Xinli Hu; Jorge Esparza Gordillo; Nina Mars; Margit Pelkonen; Paula Kauppi; Hannu Kankaanranta; Terttu Harju; David Close; Steven Greenberg; Hubert Chen; Jo Betts; Soumitra Ghosh; Veikko Salomaa; Teemu Niiranen; Markus Juonala; Kaj Metsärinne; Mika Kähönen; Juhani Junttila; Markku Laakso; Jussi Pihlajamäki; Juha Sinisalo; Marja-Riitta Taskinen; Tiinamaija Tuomi; Jari Laukkanen; Ben Challis; Andrew S. Peterson; Audrey Y. Chu; Jaakko Parkkinen; Melissa Miller; Anthony Muslin; Heikki Joensuu; Tuomo Meretoja; Lauri Aaltonen; Annika Auranen; Peeter Karihtala; Saila Kauppila; Päivi Auvinen; Elenius; Relja Popovic; Jeff Waring; Athena Matakidou; Jennifer L. Schutzman; Andrey Loboda; Aparna Chhibber; Heli Lehtonen; Stefan McDonough; Marika Crohns; Diptee Kulkarni; Kai Kaarniranta; Joni A. Turunen; Terhi Ollila; Sanna Seitsonen; Hannu Uusitalo; Vesa Aaltonen; Hannele Uusitalo-Järvinen; Marja Luodonpää; Nina Hautala; Heiko Runz; Erich C. Strauss; Hao Chen; Anna Podgornaia; Vinay Mehta; Joshua Hoffman; Kaisa Tasanen; Laura Huilaja; Katariina Hannula-Jouppi; Teea Salmi; Sirkku Peltonen; Leena Koulu; Ilkka Harvima; Kirsi Kalpala; Ying Wu; David Choy; John Michon; Nizar Smaoui; Fedik Rahimov; Anne Lehtonen; Dawn Waterworth; Risto Kajanne; Ulrike Lyhs; Mari Kaunisto; Justin Wade Davis; Bridget Riley-Gillis; Danjuma Quarless; Slavé Petrovski; Jimmy Liu; Chia-Yen Chen; Paola G. Bronson; Robert Yang; Joseph Maranville; Diana Chang; Julie Hunkapiller; Tushar Bhangale; Dorothée Diogo; Emily Holzinger; Padhraig Gormley; Xulong Wang; Xing Chen; Åsa Hedman; Kirsi Auro; Clarence Wang; Ethan Xu; Franck Auge; Clement Chatelain; Mitja Kurki; Juha Karjalainen; Aki S. Havulinna; Anu Jalanko; Kimmo Palin; Pietro della Briotta Parolo; Wei Zhou; Manuel Rivas; Aarno Palotie; Arto Lehisto; Andrea Ganna; Vincent Llorens; Antti Karlsson; Kati Hyvärinen; Jarmo Ritari; Tiina Wahlfors; Miika Koskinen; Johannes Kettunen; Katri Pylkäs; Marita Kalaoja; Minna Karjalainen; Tuomo Mantere; Eeva Kangasniemi; Sami Heikkinen; Arto Mannermaa; Eija Laakkonen; Juha Kononen; Anu Loukola; Päivi Laiho; Tuuli Sistonen; Essi Kaiharju; Markku Laukkanen; Elina Järvensivu; Sini Lähteenmäki; Lotta Männikkö; Regis Wong; Kati Kristiansson; Hannele Mattsson; Tero Hiekkalinna; Manuel González Jiménez; Kati Donner; Kalle Pärn; Javier Nunez-Fontarnau; Jarmo Harju; Elina Kilpeläinen; Georg Brein; Alexander Dada; Ghazal Awaisa; Anastasia Shcherban; Timo P. Sipilä; Hannele Laivuori; Susanna Lemmelä; Tuomo T. J. Kiiskinen; Tarja Laitinen; Harri Siirtola; Javier Gracia Tabuenca; Lila Kallio; Sirpa Soini; Jukka Partanen; Kimmo Pitkänen; Seppo Vainio; Kimmo Savinainen; Veli-Matti Kosma; Teijo Kuopio; Mary Pat Reeve; Priit Palta; Marko Salmi; Sirpa Jalkanen; Ari Ahola-Olli; Aarno Palotie; Veikko Salomaa; Mark J. Daly; Matti Pirinen; Samuli Ripatti; Jukka Koskela
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Identification of Acute Giant Cell Arteritis in Real-World Data Using Administrative Claims-Based Algorithms
ACR Open Rheumatology, ISSN: 25785745
Hemin Lee; Sara K. Tedeschi; Sarah K. Chen; Paul A. Monach; Erin Kim; Jun Liu; Attila Pethoe-Schramm; Vincent Yau; Seoyoung C. Kim
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Long-Term Stability of Anti-Vascular Endothelial Growth Factor (a-VEGF) Biologics Under Physiologically Relevant Conditions and Its Impact on the Development of Long-Acting Delivery Systems
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Debby P. Chang; Shalini Burra; Eric S. Day; Joyce Chan; Laetitia Comps-Agrar; Thierry Nivaggioli; Karthikan Rajagopal
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Estimated Impact of Public and Private Sector COVID-19 Diagnostics and Treatments on US Healthcare Resource Utilization
Advances in Therapy, ISSN: 18658652 0741238X
Daniel M. Sheinson; William B. Wong; Caroline E. Solon; Mindy M. Cheng; Anuj Shah; David Elsea; Yang Meng
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Development of a practical synthesis to PI3K α-selective inhibitor GDC-0326
Tetrahedron, ISSN: 14645416 00404020
Stefan G. Koenig; Keena L. Green; Barbara Müller; C. Gregory Sowell; David Askin; Francis Gosselin
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Cp*Rh(III)-Catalyzed C8 C−H Alkylation of Quinoline N-Oxides with Diazo Meldrum's Acid
European Journal of Organic Chemistry, ISSN: 10990690 1434193X
Malcolm P. Huestis; Jean-Philippe Leclerc; Larouche-Gauthier; Samuel Aubert-Nicol; Arun Yadav; Koilpitchai Sivamuthuraman
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A Non-covalent Ligand Reveals Biased Agonism of the TRPA1 Ion Channel
Neuron, ISSN: 10974199 08966273
Chang Liu; Rebecca M. Reese; Simon Vu; Lionel Rouge; Shannon D. Shields; Satoko Kakiuchi-Kiyota; Huifen Chen; Kevin Johnson; Yu Patrick Shi; Tania Chernov-Rogan; Demi Maria Zabala Greiner; Pawan Bir Kohli; David Hackos; Bobby Brillantes; Christine Tam; Tianbo Li; Jianyong Wang; Brian S. Safina; Steven Magnuson; Matthew Volgraf; Jian Payandeh; Jie Zheng; Alexis Rohou; Jun Chen
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Phase I basket study of taselisib, an isoform-selective PI3K inhibitor, in patients with PIK3CA-mutant cancers
Clinical Cancer Research, ISSN: 15573265 10780432
Komal Jhaveri; Matthew T. Chang; Dejan Juric; Saura; Valentina Gambardella; Anton Melnyk; Manish R. Patel; Vincent Ribrag; Cynthia X. Ma; Raid Aljumaily; Philippe L. Bedard; Jasgit C. Sachdev; Lara Dunn; Won; John Bond; Surai Jones; Heidi Savage; Maurizio Scaltriti; Wilson; Michael C. Wei; David Hyman
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Tuning MPL signaling to influence hematopoietic stem cell differentiation and inhibit essential thrombocythemia progenitors
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 10916490 00278424
Lu Cui; Ignacio Moraga; Tristan Lerbs; Camille van Neste; Stephan Wilmes; Naotaka Tsutsumi; Aaron Claudius Trotman-Grant; Milica Gakovic; Sarah Andrews; Jason Gotlib; Spyros Darmanis; Martin Enge; Stephen Quake; Ian S. Hitchcock; Jacob Piehler; Christopher Garcia; Gerlinde Wernig
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Tocilizumab in patients hospitalized with Covid-19 pneumonia
New England Journal of Medicine, ISSN: 15334406 00284793
Carlos Salama; Jian Han; Linda Yau; William Reiss; Benjamin Kramer; Jeff Neidhart; Gerard J. Criner; Emma Kaplan-Lewis; Rachel Baden; Lavannya Pandit; Miriam L. Cameron; Julia Garcia-Diaz; Victoria Chávez; Martha Mekebeb-Reuter; Ferdinando Lima De Menezes; Reena Shah; Maria F. González-Lara; Beverly Assman; Jamie Freedman; Shalini V. Mohan
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A novel method for preparing stabilized amorphous solid dispersion drug formulations using acoustic fusion
International Journal of Pharmaceutics, ISSN: 18733476 03785173
Zack Guo; Christopher Boyce; Timothy Rhodes; Lina Liu; Gino M. Salituro; Keun-joong Lee; Annette Bak; Dennis H. Leung
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Impact of polymer type, ASD loading and polymer-drug ratio on ASD tablet disintegration and drug release
International Journal of Pharmaceutics, ISSN: 18733476 03785173
Wei Zhang; Ryan Noland; Steven Chin; Milan Petkovic; Ruth Zuniga; Bethany Santarra; Breanna Conklin; Hao Helen Hou; Karthik Nagapudi; Jason Gruenhagen; Peter M. Yehl; Tao Chen
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Isothermal Crystallization Monitoring and Time-Temperature-Transformation of Amorphous GDC-0276: Differential Scanning Calorimetric and Rheological Measurements
Molecular Pharmaceutics, ISSN: 15438392 15438384
Sixue Cheng; Paroma Chakravarty; Karthik Nagapudi; Gregory B. Mckenna
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Development of AITC-induced dermal blood flow as a translational in vivo biomarker of TRPA1 activity in human and rodent skin
British Journal of Clinical Pharmacology, ISSN: 13652125 03065251
Victory Joseph; Xiaoying Yang; Simon S. Gao; Justin Elstrott; Robby M. Weimer; Wiebke Theess; Cory Thrasher; Nand Singh; Joseph Lin; Rebecca N. Bauer
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Comparative assessment for rat strain differences in metabolic profiles of 14 drugs in Wistar Han and Sprague Dawley hepatocytes
Xenobiotica, ISSN: 13665928 00498254
Wei Wang; Mulder Teresa; Jingwei Cai; Chenghong Zhang; Susan C. Wong; Zhengyin Yan; S. Cyrus Khojasteh; Donglu Zhang
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Genetics meets proteomics: perspectives for large population-based studies
Nature Reviews Genetics, ISSN: 14710064 14710056
Karsten Suhre; Mark I. McCarthy; Jochen M. Schwenk
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Baseline Factors Associated with Diabetic Retinopathy Improvement in RIDE/RISE
Ophthalmology Retina, ISSN: 24686530
Dilsher S. Dhoot; Lauren Hill; Avanti Ghanekar; Kathleen Wade Tarnowski; Ferhina S. Ali
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Development of liver microtissues with functional biliary ductular network
Biotechnology and Bioengineering, ISSN: 10970290 00063592
Ehab O. A. Hafiz; Beyza Bulutoglu; Soheir S. Mansy; Yibin Chen; Hoda Abu-Taleb; Somia A. M. Soliman; Ali A. F. El-Hindawi; Martin L. Yarmush; Basak E. Uygun
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Using forced vital capacity (FVC) in the clinic to monitor patients with idiopathic pulmonary fibrosis (IPF): pros and cons
Expert Review of Respiratory Medicine, ISSN: 17476356 17476348
Steven D Nathan; Jack Wanger; Joseph D. Zibrak; Mark L. Wencel; Cindy Burg; John L. Stauffer
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Evaluation of a Competitive Equilibrium Dialysis Approach for Assessing the Impact of Protein Binding on Clearance Predictions
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Robert S. Jones; Jae H. Chang; Mauricio Flores; Elliot Brecht
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Genome-wide association study identifies 48 common genetic variants associated with handedness
Nature Human Behaviour, ISSN: 23973374
Gabriel Cuellar-Partida; Joyce Y. Tung; Nicholas Eriksson; Eva Albrecht; Fazil Aliev; Ole A. Andreassen; Ines Barroso; Jacques S. Beckmann; Marco P. Boks; Dorret I. Boomsma; Heather A. Boyd; Monique M. B. Breteler; Harry Campbell; Daniel I. Chasman; Lynn F. Cherkas; Gareth E. Davies; Eco J. C. de Geus; Ian J. Deary; Panos Deloukas; Danielle M. Dick; David L. Duffy; Johan G. Eriksson; Tõnu Esko; Bjarke Feenstra; Frank Geller; Christian Gieger; Ina Giegling; Scott D Gordon; Jiali Han; Thomas Hansen; Annette M. Hartmann; Caroline Hayward; Kauko Heikkilä; Andrew A Hicks; Joel N. Hirschhorn; Jouke-Jan Hottenga; Jennifer E. Huffman; Liang-Dar Hwang; M Arfan Ikram; Jaakko Kaprio; John P. Kemp; Kay-Tee Khaw; Norman Klopp; Bettina Konte; Zoltán Kutalik; Jari Lahti; Xin Li; Ruth J. F. Loos; Michelle Luciano; Sigurdur H. Magnusson; Massimo Mangino; Pedro Marques-Vidal; Nicholas G Martin; Wendy L. McArdle; Mark I. McCarthy; Carolina Medina-Gomez; Mads Melbye; Scott A. Melville; Andres Metspalu; Lili Milani; Vincent Mooser; Mari Nelis; Dale R Nyholt; Kevin S. O’Connell; Roel A. Ophoff; Cameron Palmer; Aarno Palotie; Teemu Palviainen; Guillaume Pare; Lavinia Paternoster; Leena Peltonen; Brenda W. J. H. Penninx; Ozren Polasek; Peter P Pramstaller; Inga Prokopenko; Katri Räikkönen; Samuli Ripatti; Fernando Rivadeneira; Igor Rudan; Dan Rujescu; Johannes H. Smit; George Davey Smith; Jordan W. Smoller; Nicole Soranzo; Tim D. Spector; Beate St Pourcain; John M Starr; Hreinn Stefansson; Stacy Steinberg; Maris Teder-Laving; Gudmar Thorleifsson; Kari Stefansson; Nicholas J. Timpson; Clive Holmes; Cornelia M. van Duijn; Frank J A van Rooij; Jaqueline M. Vink; Peter Vollenweider; Eero Vuoksimaa; Gérard Waeber; Nicholas J Wareham; Nicole M. Warrington; Dawn Waterworth; Thomas Werge; H.-Erich Wichmann; Elisabeth Widén; Gonneke Willemsen; Alan F. Wright; Margaret J. Wright; Mousheng Xu; Jing Hua Zhao; Peter Kraft; David Hinds; Cecilia M. Lindgren; Reedik Mägi; Neale; David C. Evans; Sarah E. Medland
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Multisite supply planning for drug products under uncertainty
AIChE Journal, ISSN: 15475905 00011541
Apoorva M. Sampat; Ranjeet Kumar; Remya Pushpangatha Kurup; Kawa Chiu; Victor Saucedo; Victor M. Zavala
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Kinase inhibition in autoimmunity and inflammation
Nature Reviews Drug Discovery, ISSN: 14741784 14741776
Ali A. Zarrin; Katherine Bao; Patrick J. Lupardus; Domagoj Vucic
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The Utility of Novel Urinary Biomarkers in Mice for Drug Development Studies
International Journal of Toxicology, ISSN: 1092874X 10915818
Adedeji; Yi-Zhong Gu; Tony Pourmohamad; Justin Kanerva; Yafei Chen; Elnaz Atabakhsh; Michael R. Tackett; Feifei Chen; Bhavana Bhatt; Thierry Gury; Olivier Dorchies; Manisha Sonee; Michelle Morgan; Jennifer Burkey; Jean-Charles Gautier; James E. McDuffie
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Correction to: The role of physical activity in metabolic homeostasis before and after the onset of type 2 diabetes: an IMI DIRECT study (Diabetologia, (2020), 63, 4, (744-756), 10.1007/s00125-019-05083-6)
Diabetologia, ISSN: 14320428 0012186X
Robert W. Koivula; Naeimeh Atabaki-Pasdar; Giuseppe N. Giordano; Tom White; Jerzy Adamski; Jimmy D. Bell; Joline Beulens; Søren Brage; Søren Brunak; Federico De Masi; Emmanouil T. Dermitzakis; Ian M. Forgie; Gary Frost; Torben Hansen; Tue H. Hansen; Andrew T. Hattersley; Tarja Kokkola; Azra Kurbasic; Markku Laakso; Andrea Mari; Timothy J. McDonald; Oluf Pedersen; Femke Rutters; Jochen M. Schwenk; Harriet J. A. Teare; E. Louise Thomas; Ana Vinuela; Anubha Mahajan; Mark I. McCarthy; Hartmut Ruetten; Mark Walker; Ewan Pearson; Imre Pavo; Paul W. Franks
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Phase 2, multicenter GIBB study of obinutuzumab plus bendamustine in previously untreated patients with chronic lymphocytic leukemia
Leukemia and Lymphoma, ISSN: 10292403 10428194
Jeff P. Sharman; John M. Burke; Habte A. Yimer; Michael Boxer; Sunil Babu; Jia Li; Yong Mun; Alexey V. Danilov
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Reply
Journal of Allergy and Clinical Immunology, ISSN: 10976825 00916749
Philippe Gevaert; Jonathan Corren; Joaquim Mullol; Joseph Han; Stella E. Lee; Monica Ligueros-Saylan; Kit Wong; Theodore A. Omachi; Claus Bachert
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Atezolizumab Versus Docetaxel in Pretreated Patients With NSCLC: Final Results From the Randomized Phase 2 POPLAR and Phase 3 OAK Clinical Trials
Journal of Thoracic Oncology, ISSN: 15561380 15560864
Julien Mazieres; Achim Rittmeyer; Shirish M. Gadgeel; Toyoaki Hida; David R. Gandara; Diego L Cortinovis; Fabrice Barlesi; Wei Yu; Christina Matheny; Ballinger; Keunchil Park
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Application of Machine Learning for Tumor Growth Inhibition – Overall Survival Modeling Platform
CPT: Pharmacometrics and Systems Pharmacology, ISSN: 21638306
Phyllis Chan; Xiaofei Zhou; Nina Wang; Qi Liu; Rene Bruno; Jin Yan Jin
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Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, ISSN: 15206904 00223263
Benjamin I. Andrews; Firoz D. Antia; Shawn B. Brueggemeier; Louis Diorazio; Stefan G. Koenig; Michael E. Kopach; Heewon Lee; Martin Olbrich; Anna L. Watson
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Evaluation of the effect of prospective biomarker testing on progression-free survival in diffuse large B-cell lymphoma
Leukemia and Lymphoma, ISSN: 10292403 10428194
Edith Szafer-Glusman; Juan Liu; Arijit Sinha; Franklin V. Peale Jr.; Jill M. Ray; Carsten Horn; Mikkel Z. Oestergaard; Martin Kornacker; Laurie H. Sehn; Umberto Vitolo; Andrea Knapp; Jeffrey M. Venstrom; Michelle Byrtek; Elizabeth A. Punnoose
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