Scientists / Publications

Publications

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DISPLAYING 4701 - 4750 OF 15714 RESULTS

Effect of Disease Activity, Glucocorticoid Exposure, and Rituximab on Body Composition During Induction Treatment of Antineutrophil Cytoplasmic Antibody–Associated Vasculitis
Arthritis Care and Research, ISSN: 21514658 2151464X
Zachary S. Wallace; Miloslavsky; Matthew Cascino; Sebastian Unizony; Na Lu; Hoffman; Cees Kallenberg; Langford; Merkel; Paul A. Monach; Seo; Spiera; E. William St. Clair; Specks; Paul Brunetta; Hyon Choi; John H. Stone
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Diverse ubiquitin linkages regulate RIP kinases-mediated inflammatory and cell death signaling
Cell Death and Differentiation, ISSN: 14765403 13509047
Axel Witt; Domagoj Vucic
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Flow Function of Pharmaceutical Powders Is Predominantly Governed by Cohesion, Not by Friction Coefficients
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Lap Yin Leung; Chen Mao; Ishan Srivastava; Ping Du; Yi Yang
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Evaluation of an fMRI USPIO-based assay in healthy human volunteers
Journal of Magnetic Resonance Imaging, ISSN: 15222586 10531807
Richard Baumgartner; William Cho; Alexandre Coimbra; Christopher Chen; Zaiqi Wang; Arie Struyk; Narayanaswamy Venketasubramanian; May Low; Cindy Gargano; Fuqiang Zhao; Donald Williams; Torsten Reese; Stephanie Seah; Dai Feng; Sonya Apreleva; Esben Petersen; Jeffrey L. Evelhoch
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Results of a harmonized endotoxin recovery study protocol evaluation by 14 BioPhorum Operations Group (BPOG) member companies
Biologicals, ISSN: 10958320 10451056
Jay Bolden; Michael Knight; Shahrzad Stockman; Bastian Omokoko
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Pharmacokinetics and safety of vismodegib in patients with advanced solid malignancies and hepatic impairment
Cancer Chemotherapy and Pharmacology, ISSN: 14320843 03445704
Ghassan K. Abou-Alfa; Lionel D. Lewis; Patricia M. LoRusso; Michael Maitland; Priya Chandra; Sravanthi Cheeti; Dawn Colburn; Sarah Williams; Brian Simmons; Richard A. Graham
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Randomized phase II trial of parsatuzumab (Anti-EGFL7) or placebo in combination with FOLFOX and bevacizumab for first-line metastatic colorectal cancer
Oncologist, ISSN: 1549490X 10837159
Rocío García-Carbonero; Eric Van Cutsem; Rivera; Jacek Jassem; Ira Gore; Niall C. Tebbutt; Fadi S. Braiteh; Guillem Argiles; Zev A. Wainberg; Roel Funke; Maria Anderson; Bruce Mccall; Mark Stroh; Eric Wakshull; Priti Hegde; Weilan Ye; Daniel S. Chen; Ilsung Chang; Ina Rhee; Herbert Hurwitz
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A phase 1 study to evaluate the safety and LDL cholesterol–lowering effects of RG7652, a fully human monoclonal antibody against proprotein convertase subtilisin/kexin type 9
Clinical Cardiology, ISSN: 19328737 01609289
Amos Baruch; Diana Luca; Robert S. Kahn; Kyra J. Cowan; Maya Leabman; Nageshwar Budha; Cecilia Chiu; Yan Wu; Daniel Kirchhofer; Andrew S. Peterson; John C. Davis; Whittemore G. Tingley
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A randomized multicenter study evaluating Xolair persistence of response after long-term therapy
Journal of Allergy and Clinical Immunology, ISSN: 10976825 00916749
Dennis Ledford; William W. Busse; Benjamin L. Trzaskoma; Theodore A. Omachi; Karin Rosén; Bradley E. Chipps; Allan T. Luskin; Paul G. Solari
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Examining the reliability and validity of the Clinical Assessment Interview for Negative Symptoms within the Management of Schizophrenia in Clinical Practice (MOSAIC) multisite national study
Schizophrenia Research, ISSN: 15732509 09209964
Jack J. Blanchard; Kristen R. Bradshaw; Cristina P. Garcia; Henry A. Nasrallah; Philip D. Harvey; Daniel Casey; Csilla Csoboth; James I. Hudson; Laura Julian; Lentz; Keith H. Nuechterlein; Diana O. Perkins; Tracey G. Skale; Lonnie R. Snowden; Rajiv Tandon; Cenk Tek; Dawn Velligan; Sophia Vinogradov; Cedric O'Gorman
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Cardiotoxicity Associated with Nicotinamide Phosphoribosyltransferase Inhibitors in Rodents and in Rat and Human-Derived Cells Lines
Cardiovascular Toxicology, ISSN: 15590259 15307905
Misner; Ariel Kauss; Jatinder Singh; Hirdesh Uppal; Bruening-Wright; Bianca M. Liederer; Tori Lin; Bobbi McCray; Nghi La; Trung Nguyen; Deepak Sampath; Peter Dragovich; Thomas O’Brien; Tanja S. Zabka
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Type 2 immunity is protective in metabolic disease but exacerbates NAFLD collaboratively with TGF-b
Science Translational Medicine, ISSN: 19466242 19466234
Kevin M. Hart; Thomas Fabre; Joshua C. Sciurba; Richard L. Gieseck; Lee A. Borthwick; Kevin M. Vannella; Thomas H. Acciani; Rafael De Queiroz Prado; Robert W. Thompson; Sandra White; Genevieve Soucy; Marc Bilodeau; Thirumalai R. Ramalingam; Joseph R. Arron; Naglaa H. Shoukry; Thomas A. Wynn
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A Comparison of Quantum and Molecular Mechanical Methods to Estimate Strain Energy in Druglike Fragments
Journal of Chemical Information and Modeling, ISSN: 15205142 15499596
Benjamin D. Sellers; Natalie C. James; Alberto Gobbi
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A Comparison of Quantum and Molecular Mechanical Methods to Estimate Strain Energy in Druglike Fragments
Journal of Chemical Information and Modeling, ISSN: 1549960X 15499596
Benjamin D. Sellers; Natalie C. James; Alberto Gobbi
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Clinical features of serous retinopathy observed with cobimetinib in patients with BRAF-mutated melanoma treated in the randomized coBRIM study
Journal of Translational Medicine, ISSN: 14795876
Luis De La Cruz-Merino; Lorenza Di Guardo; Jean-Jacques Grob; Alfredo Venosa; James Larkin; McArthur; Antoni Ribas; Paolo A. Ascierto; Jeffrey T.R. Evans; Antonio Gomez-Escobar; Giulio Barteselli; Susan Eng; Jessie Hsu; Anne Uyei; Brigitte Dréno
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Targeting factor D of the alternative complement pathway reduces geographic atrophy progression secondary to age-related macular degeneration
Science Translational Medicine, ISSN: 19466242 19466234
Brian L. Yaspan; David F. Williams; Frank G. Holz; Carl D. Regillo; Zhengrong Li; Amy Dressen; Menno Van Lookeren Campagne; Kha Le; Robert R. Graham; Tatiana Beres; Tushar Bhangale; Lee Honigberg; Ashley Smith; Erin C. Henry; Carole Ho; Erich C. Strauss
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New Cancer Immunotherapy Agents in Development: A report from an associated program of the 31stAnnual Meeting of the Society for Immunotherapy of Cancer, 2016
Journal for ImmunoTherapy of Cancer, ISSN: 20511426
Prasad S. Adusumilli; Edward Cha; Mark Cornfeld; Thomas Davis; Adi Diab; Thomas W. Dubensky; Elizabeth Evans; Jane L. Grogan; Bryan Irving; Rom S. Leidner; Shane A. Olwill; Patrick Soon-Shiong; Frederic Triebel; David Tuck; Adrian Bot; Roger D. Dansey; Charles G. Drake; Gordon J. Freeman; Ramy Ibrahim; Salil Patel; Daniel S. Chen
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Impact of pharmacy channel on adherence to oral oncolytics
BMC Health Services Research, ISSN: 14726963
Michael Stokes; Carolina Reyes; Yu Xia; Veronica Alas; Hans-Peter Goertz; Luke Boulanger
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Crystal structure of Mdm12 and combinatorial reconstitution of Mdm12/Mmm1 ERMES complexes for structural studies
Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X
Andrew P. AhYoung; Brian Lu; Duilio Cascio; Pascal F. Egea
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18F-fluoroestradiol PET/CT measurement of estrogen receptor suppression during a phase I trial of the novel estrogen receptor-targeted therapeutic GDC-0810: Using an imaging biomarker to guide drug dosage in subsequent trials
Clinical Cancer Research, ISSN: 15573265 10780432
Yingbing Wang; Karen L. Ayres; Debra A. Goldman; Maura N. Dickler; Aditya Bardia; Ingrid A. Mayer; Eric P. Winer; Jill Fredrickson; Carlos L. Arteaga; Baselga; H. Charles Manning; Umar Mahmood; Gary A. Ulaner
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XenMine: A genomic interaction tool for the Xenopus community
Developmental Biology, ISSN: 1095564X 00121606
Christine D. Reid; Kalpana Karra; Jessica Chang; Robert Piskol; Qin Li; Jin Billy Li; J. Michael Cherry; Julie C. Baker
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Chemalot and chemalot-knime: Command line programs as workflow tools for drug discovery
Journal of Cheminformatics, ISSN: 17582946
Man-Ling Lee; Ignacio Aliagas; Jianwen A. Feng; Thomas Gabriel; O'Donnell; Benjamin D. Sellers; Bernd Wiswedel; Alberto Gobbi
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Discovery of Potent and Selective Tricyclic Inhibitors of Bruton's Tyrosine Kinase with Improved Druglike Properties
ACS Medicinal Chemistry Letters, ISSN: 19485875
Xiaojing Wang; Jim Barbosa; Peter Blomgren; Meire C. Bremer; Jacob Z. Chen; James J. Crawford; Wei Deng; Liming Dong; Eigenbrot; Steven L. Gallion; Jonathan Hau; Huiyong Hu; Adam R. Johnson; Arna Katewa; Jeffrey E. Kropf; Seung H. Lee; Lichuan Liu; Joseph W. Lubach; Jen MacAluso; Patricia M. MacIejewski; Scott A. Mitchell; Daniel F. Ortwine; Julie Dipaolo; Karin Reif; Heleen Scheerens; Aaron Schmitt; Harvey Wong; Jin-Ming Xiong; Jianjun Xu; Zhongdong Zhao; Fusheng Zhou; Kevin S. Currie; Wendy B. Young
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Impact of Supramolecular Aggregation on the Crystallization Kinetics of Organic Compounds from the Supercooled Liquid State
Molecular Pharmaceutics, ISSN: 15438392 15438384
Arjun Kalra; Patrick Tishmack; Joseph W. Lubach; Eric Munson; Lynne S. Taylor; Stephen Byrn; Tonglei Li
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Bio-Orthogonal Cross-Linking Chemistry Enables in Situ Protein Encapsulation and Provides Sustained Release from Hyaluronic Acid Based Hydrogels
Molecular Pharmaceutics, ISSN: 15438392 15438384
Amin Famili; Karthikan Rajagopal
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A multi-matrix HILIC-MS/MS method for the quantitation of endogenous small molecule neurological biomarker N-acetyl aspartic acid (NAA)
Journal of Pharmaceutical and Biomedical Analysis, ISSN: 1873264X 07317085
Dewakar Sangaraju; Sheerin Shahidi-Latham; Braydon Burgess; Brian J. Dean; Xiao Ding
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Prospects and progress of atezolizumab in non-small cell lung cancer
Expert Opinion on Biological Therapy, ISSN: 17447682 14712598
Johan Vansteenkiste; Els Wauters; Keunchil Park; Achim Rittmeyer; Alan Sandler; Alexander Spira
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Chemoselective Copper-Catalyzed Ullmann-Type Coupling of Oxazolidinones with Bromoiodoarenes
Organic Letters, ISSN: 15237052 15237060
Sean M. Kelly; Chong Han; Laura Tung; Francis Gosselin
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The effects of drug metabolizing enzyme inhibitors on hepatic efflux and uptake transporters
Drug Metabolism Letters, ISSN: 18723128
Jonathan Cheong; Jason S Halladay; Emile G. Plise; Jasleen K. Sodhi; Laurent Salphati
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Performance evaluation of three platforms with ultrasensitive ligand-binding assay potential
Bioanalysis, ISSN: 17576199 17576180
Kyra J. Cowan; Albert Geiger; Hans Hornauer; Robyn Rourick; Patricia Siguenza
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Interleukin 4 promotes the development of ex-Foxp3 Th2 cells during immunity to intestinal helminths
Journal of Experimental Medicine, ISSN: 15409538 00221007
Victoria S. Pelly; Stephanie M. Coomes; Yashaswini Kannan; Manolis Gialitakis; Lewis J. Entwistle; Jimena Perez-Lloret; Stephanie Czieso; Isobel S. Okoye; Dominik Rückerl; Judith E. Allen; Frank Brombacher; Mark S. Wilson
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Time-to-event analysis of polatuzumab vedotin-induced peripheral neuropathy to assist in the comparison of clinical dosing regimens
CPT: Pharmacometrics and Systems Pharmacology, ISSN: 21638306
Dan Lu; Gillespie; Sandhya Girish; Priya Agarwal; Chunze Li; Jamie Hirata; Yu-Waye Chu; Kagedal; Leon; Maiya; Jin Y. Jin
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Trastuzumab emtansine versus capecitabine plus lapatinib in patients with previously treated HER2-positive advanced breast cancer (EMILIA): a descriptive analysis of final overall survival results from a randomised, open-label, phase 3 trial
The Lancet Oncology, ISSN: 14745488 14702045
Diéras; David W. Miles; Sunil Verma; Pegram; Manfred Welslau; Baselga; Ian E. Krop; Kimberly Blackwell; Silke Hoersch; Xu; Marjorie Green; Luca Gianni
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Developments in therapy with monoclonal antibodies and related proteins
Clinical Medicine, Journal of the Royal College of Physicians of London, ISSN: 14734893 14702118
Shepard; Gail L. Phillips; Christopher D. Thanos; Marc Feldmann
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Rituximab treatment circumvents the prognostic impact of tumor-infiltrating T-cells in follicular lymphoma patients
Human Pathology, ISSN: 15328392 00468177
Luc Xerri; Sarah Huet; Jeffrey M. Venstrom; Edith Szafer-Glusman; Bettina Fabiani; Danielle Canioni; Catherine Chassagne-Clément; Peggy Dartigues-Cuilléres; Fréderic Charlotte; Camille Laurent; Benedicte Gelas-Dore; Christopher R. Bolen; Elizabeth A. Punnoose; Reda Bouabdallah; Pauline Brice; Morschhauser; Guillaume Cartron; Daniel Olive; Gilles Salles
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Cardiovascular Safety of Tocilizumab Versus Tumor Necrosis Factor Inhibitors in Patients With Rheumatoid Arthritis: A Multi-Database Cohort Study
Arthritis and Rheumatology, ISSN: 23265205 23265191
Seoyoung C. Kim; Daniel H. Solomon; James R. Rogers; Sara Gale; Micki Klearman; Khaled Sarsour; Sebastian Schneeweiss
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TREM2, Microglia, and Neurodegenerative Diseases
Trends in Molecular Medicine, ISSN: 1471499X 14714914
Felix L. Yeh; David V. Hansen; Morgan Sheng
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Applying stable isotope labeled amino acids in micropatterned hepatocyte coculture to directly determine the degradation rate constant for CYP3A4
Drug Metabolism and Disposition, ISSN: 1521009X 00909556
Ryan Takahashi; Sheerin Shahidi-Latham; Susan C. Wong; Jae H. Chang
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Characterizing neoantigens for personalized cancer immunotherapy
Current Opinion in Immunology, ISSN: 18790372 09527915
Aude-Hélène Capietto; Suchit Jhunjhunwala; Lélia Delamarre
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Responsiveness of the national eye institute visual function questionnaire-25 to visual acuity gains in patients with diabetic macular edema: Evidence from the RIDE and RISE Trials
Retina, ISSN: 15392864 0275004X
Ivan J. Suñer; Neil M. Bressler; Rohit Varma; Chantal M. Dolan; James Ward; Adam Turpcu
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BCL2 mutations do not confer adverse prognosis in follicular lymphoma patients treated with rituximab
American Journal of Hematology, ISSN: 10968652 03618609
Sarah Huet; Edith Szafer-Glusman; Bruno Tesson; Luc Xerri; Wayne J. Fairbrother; Kiran Mukhyala; Christopher R. Bolen; Elizabeth A. Punnoose; Laurie Tonon; Catherine Chassagne-Clément; Pierre Feugier; Alain Viari; Fabrice Jardin; Gilles Salles; Pierre Sujobert
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Inflammation and immunogenicity limit the utility of the rabbit as a nonclinical species for ocular biologic therapeutics
Regulatory Toxicology and Pharmacology, ISSN: 10960295 02732300
Christina de Zafra; Vito G. Sasseville; Steven Matsumoto; Christian Freichel; Milton; Timothy K. MacLachlan; Cindy A. Farman; Iona Raymond; Swati Gupta; Ronald Newton; Elke-Astrid Atzpodien; Evan A Thackaberry
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Serious adverse effects associated with glucocorticoid therapy in patients with giant cell arteritis (GCA): A nested case–control analysis
Seminars in Arthritis and Rheumatism, ISSN: 1532866X 00490172
Jessica C. Wilson; Khaled Sarsour; Neil Collinson; Katie Tuckwell; David Musselman; Micki Klearman; Pavel Napalkov; Susan S. Jick; John H. Stone; Christoph R. Meier
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Low immunogenicity of tocilizumab in patients with rheumatoid arthritis
Annals of the Rheumatic Diseases, ISSN: 14682060 00034967
Gerd R. Burmester; Ernest Choy; Alan Kivitz; Atsushi Ogata; Bao; Akira Nomura; Stuart Lacey; Jinglan Pei; William Reiss; Attila Pethoe-Schramm; Navita L. Mallalieu; Thomas Wallace; Margaret Michalska; Herbert Birnboeck; Kay Stubenrauch; Mark C. Genovese
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Notch1 and Notch2 receptors regulate mouse and human gastric antral epithelial cell homoeostasis
Gut, ISSN: 14683288 00175749
Gail B. Gifford; Elise S. Demitrack; Theresa M. Keeley; Andrew Tam; Nilsa La Cunza; Priya H. Dedhia; Jason R. Spence; Diane M. Simeone; Ichiko Saotome; Angeliki Louvi; Christian W. Siebel; Linda C. Samuelson
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Concomitant Use of Statins in Tocilizumab-Treated Patients with Rheumatoid Arthritis: A Post Hoc Analysis
Rheumatology and Therapy, ISSN: 21986584 21986576
Martin Soubrier; Jinglan Pei; Frédérick Durand; Lars Gullestad; Ani John
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Stem cell plasticity enables hair regeneration following Lgr5 + cell loss
Nature Cell Biology, ISSN: 14764679 14657392
Joerg D. Hoeck; Brian Biehs; Antonina V. Kurtova; Noelyn Kljavin; Felipe de Sousa e Melo; Bruno Alicke; Koeppen; Zora Modrusan; Robert Piskol; Frederic J. De Sauvage
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Discovery of 5-Azaindazole (GNE-955) as a Potent Pan-Pim Inhibitor with Optimized Bioavailability
Journal of Medicinal Chemistry, ISSN: 15204804 00222623
Xiaojing Wang; Aleksandr Kolesnikov; Suzanne Tay; Grace Chan; Qi Chao; Steven Do; Jason H. Drummond; Allen Ebens; Ning Liu; Justin Ly; Eric Harstad; Huiyong Hu; John Moffat; Veerendra Munugalavadla; Jeremy Murray; Dionysos S. Slaga; Vickie Tsui; Matthew Volgraf; Heidi J. A. Wallweber; Jae H. Chang
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A survey of renal impairment pharmacokinetic studies for new oncology drug approvals in the USA from 2010 to early 2015: A focus on development strategies and future directions
Anti-Cancer Drugs, ISSN: 14735741 09594973
Jim J. Xiao; Jiyun S. Chen; Bert L. Lum; Richard A. Graham
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Mechanical ventilation in idiopathic pulmonary fibrosis: A nationwide analysis of ventilator use, outcomes, and resource burden
BMC Pulmonary Medicine, ISSN: 14712466
Joshua J. Mooney; Karina Raimundo; Eunice Chang; Michael S. Broder
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