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Publications

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DISPLAYING 4701 - 4750 OF 15603 RESULTS

The Janus Kinase (JAK) FERM and SH2 domains: Bringing specificity to JAK-receptor interactions
Frontiers in Endocrinology, ISSN: 16642392
Ryan Ferrao; Patrick J. Lupardus
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The kinase TPL2 activates ERK and p38 signaling to promote neutrophilic inflammation
Science Signaling, ISSN: 19379145 19450877
Kate Senger; Victoria Pham; Eugene Varfolomeev; Jason A. Hackney; Cesar A. Corzo; Jenna L. Collier; Vivian W. C. Lau; Zhiyu Huang; Kajal Hamidzhadeh; Patrick Caplazi; Ivan Peng; A F. Setiadi; Ross Francis; Andres Paler Martinez; Youngsu C. Kwon; Vladimir Ramirez-Carrozzi; Yonglian Sun; Patricia W. Grigg; Merone Roose-Girma; Surinc Er Jeet; Kai H. Barck; Anna Pham; Naruhisa Ota; Connie Ha; Stinson; Joseph Guillory; Lucinda Tam; Zora Modrusan; Claire Emson; Brent Mckenzie; Michael J. Townsend; Richard A. D. Carano; Søren Warming; Domagoj Vucic; Jason De Voss; Wyne P. Lee; Jennie R. Lill; Ali A. Zarrin
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The kinase TPL2 activates ERK and p38 signaling to promote neutrophilic inflammation
Science Signaling, ISSN: 19450877
Kate Senger; Victoria Pham; Eugene Varfolomeev; Jason A. Hackney; Cesar A. Corzo; Jenna L. Collier; Vivian W. C. Lau; Zhiyu Huang; Kajal Hamidzhadeh; Patrick Caplazi; Ivan Peng; A F. Setiadi; Ross Francis; Andres Paler Martinez; Youngsu C. Kwon; Vladimir Ramirez-Carrozzi; Yonglian Sun; Patricia W. Grigg; Merone Roose-Girma; Surinc Er Jeet; Kai H. Barck; Anna Pham; Ota; Connie Ha; Stinson; Joseph Guillory; Lucinda Tam; Zora Modrusan; Claire Emson; Brent S. McKenzie; Michael J. Townsend; Richard A. D. Carano; Søren Warming; Domagoj Vucic; Jason De Voss; Wyne P. Lee; Jennie R. Lill; Ali A. Zarrin
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Unsaturated fatty acyl recognition by Frizzled receptors mediates dimerization upon Wnt ligand binding
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 10916490 00278424
Aaron H Nile; Susmith Mukund; Karen Stanger; Weiru Wang; Rami N. Hannoush
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The kinase TPL2 activates ERK and p38 signaling to promote neutrophilic inflammation
Science Signaling, ISSN: 19379145 19450877
Kate Senger; Victoria Pham; Eugene Varfolomeev; Jason A. Hackney; Cesar A. Corzo; Jenna L. Collier; Vivian W. C. Lau; Zhiyu Huang; Kajal Hamidzadeh; Patrick Caplazi; Ivan Peng; A F. Setiadi; Ross Francis; Andres Paler Martinez; Youngsu C. Kwon; Vladimir Ramirez-Carrozzi; Yonglian Sun; Patricia W. Grigg; Merone Roose-Girma; Surinc Er Jeet; Kai H. Barck; Anna Pham; Naruhisa Ota; Connie Ha; Stinson; Joseph Guillory; Lucinda Tam; Zora Modrusan; Claire Emson; Brent Mckenzie; Michael J. Townsend; Richard A. D. Carano; Søren Warming; Domagoj Vucic; Jason De Voss; Wyne P. Lee; Jennie R. Lill; Ali A. Zarrin
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A CEACAM6-high airway neutrophil phenotype and CEACAM6-high epithelial cells are features of severe asthma
Journal of Immunology, ISSN: 15506606 00221767
Aarti Shikotra; David F. Choy; Salman Siddiqui; Greer Arthur; Deepti R. Nagarkar; Guiquan Jia; Adam K. A. Wright; Chandra M. Ohri; Emma Doran; Claire A. Butler; Beverley Hargadon; Abbas Alexander; Janet Jackman; Lawren C. Wu; Liam G. Heaney; Joseph R. Arron; Peter Bradding
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Compatibility study of a parenteral microdose polyethylene glycol formulation in medical devices and identification of degradation impurity by 2D-LC/MS
Journal of Pharmaceutical and Biomedical Analysis, ISSN: 1873264X 07317085
Lulu Dai; Geoffrey K. Yeh; Yingqing Ran; Peter M. Yehl; Kelly Zhang
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Transcription factor Etv5 is essential for the maintenance of alveolar type II cells
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 10916490 00278424
Zhen Zhang; Kim Newton; Sarah K. Kummerfeld; Webster; Donald S. Kirkpatrick; Lilian Phu; Jeffrey Eastham-Anderson; Jinfeng Liu; Wyne P. Lee; Jiansheng Wu; Hong Li; Melissa Junttila; Vishva M. Dixit
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Genomics and evolution of protein phosphatases
Science Signaling, ISSN: 19379145 19450877
Mark J. Chen; Jack E. Dixon; Gerard Manning
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Validation of a two-dimensional liquid chromatography method for quality control testing of pharmaceutical materials
Journal of Chromatography A, ISSN: 18733778 00219673
Samuel H. Yang; Jennifer Wang; Kelly Zhang
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Btk-specific inhibition blocks pathogenic plasma cell signatures and myeloid cell–associated damage in IFNα-driven lupus nephritis
JCI insight, ISSN: 23793708
Arna Katewa; Yugang Wang; Jason A. Hackney; Tao Huang; Eric Suto; Nandhini Ramamoorthi; Cary D. Austin; Meire C. Bremer; Jacob Z. Chen; James J. Crawford; Kevin S. Currie; Peter Blomgren; Jason Devoss; Julie Dipaolo; Jonathan Hau; Adam R. Johnson; Justin Lesch; Laura DeForge; Zhonghua Lin; Marya Liimatta; Joseph W. Lubach; Sami McVay; Zora Modrusan; Allen Nguyen; Chungkee Poon; Jianyong Wang; Lichuan Liu; Wyne P. Lee; Harvey Wong; Wendy B. Young; Michael J. Townsend; Karin Reif
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Computationally Discovered Potentiating Role of Glycans on NMDA Receptors
Scientific Reports, ISSN: 20452322
Anton V. Sinitskiy; Nathaniel H. Stanley; David Hackos; Jesse E. Hanson; Benjamin D. Sellers; Vijay S. Pande
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Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands
Journal of Clinical Investigation, ISSN: 15588238 00219738
Jooho Chung; Christen Ebens; Eric Perkey; Vedran Radojcic; Ute Koch; Leonardo Scarpellino; Alexander Tong; Frederick Allen; Sherri Wood; Jiane Feng; Ann Friedman; David Granadier; Ivy T. Tran; Qian Chai; Lucas Onder; Minhong Yan; Pavan Reddy; Bruce R. Blazar; Alex Y. Huang; Todd V. Brennan; D. Keith Bishop; Burkhard Ludewig; Christian W. Siebel; Freddy Radtke; Sanjiv A. Luther; Ivan Maillard
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bisFabs: Tools for rapidly screening hybridoma IgGs for their activities as bispecific antibodies
mAbs, ISSN: 19420870 19420862
Sanket Patke; Ji Li; Peiyin Wang; Dionysos S. Slaga; Jennifer A. Johnston; Sunil Bhakta; Siler Panowski; Liping L. Sun; Teemu T. Junttila; Justin M. Scheer; Diego Ellerman
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[18F] Positron emission tomography response after rituximab-containing induction therapy in follicular lymphoma is an independent predictor of survival after adjustment for FLIPI in academic and community-based practice
Leukemia and Lymphoma, ISSN: 10292403 10428194
Ida Wong-Sefidan; Michelle Byrtek; Zhou; Jonathan W. Friedberg; Christopher R. Flowers; Zelenetz; Keith Dawson; Erin G. Reid
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Staphylococcus aureus type I signal peptidase: Essential or not essential, that’s the question
Microbial Cell, ISSN: 23112638
Wouter L. W. Hazenbos; Elizabeth Skippington; Man-Wah Tan
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Preference for subcutaneous or intravenous administration of rituximab among patients with untreated CD20+ diffuse large B-cell lymphoma or follicular lymphoma: Results from a prospective, randomized, open-label, crossover study (PrefMab)
Annals of Oncology, ISSN: 15698041 09237534
Rummel; Kim; Aversa; Wolfram Brugger; Capochiani; Plenteda; Re; Peter C. Trask; Osborne; Smith; Grigg
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Incidence and management of diarrhea in patients with HER2-positive breast cancer treated with pertuzumab
Annals of Oncology, ISSN: 15698041 09237534
Sandra M. Swain; Andreas Schneeweiss; Luca Gianni; Gao; Alisha Stein; Waldron-Lynch; Sarah Heeson; Beattie; Bongin Yoo; Javier Cortés; Baselga
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Response to "quantitative Prediction of Drug-Drug Interactions Involving Inhibitory Metabolites by Physiologically Based Pharmacokinetic Models: Is It Worth?"
CPT: Pharmacometrics and Systems Pharmacology, ISSN: 21638306
Ian E. Templeton; Yuan Chen; Jialin Mao; Jian Lin; Hongbin Yu; Peters; Shebley; Varma
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Response to "quantitative Prediction of Drug-Drug Interactions Involving Inhibitory Metabolites by Physiologically Based Pharmacokinetic Models: Is It Worth?"
CPT: Pharmacometrics and Systems Pharmacology,
Ian E. Templeton; Yuan Chen; Jialin Mao; Lin; Hongbin Yu; Peters; Shebley; Varma
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Importance of angioedema-free days in patients with chronic idiopathic or spontaneous urticaria
Annals of Allergy, Asthma and Immunology, ISSN: 15344436 10811206
James L. Zazzali; Allen P. Kaplan; Marcus Maurer; Karina Raimundo; Benjamin L. Trzaskoma; Evgeniya Antonova; Karin Rosén
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Ras-MEK signaling mediates a critical Chk1-dependent DNA damage response in cancer cells
Molecular Cancer Therapeutics, ISSN: 15388514 15357163
Ho-June Lee; Yi Cao; Victoria Pham; Elizabeth M. Blackwood; Catherine Wilson; Marie Evangelista; Christiaan N. Klijn; David Stokoe; Jeffrey Settleman
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Tools for communication: Novel infrastructure to address patient-perceived gaps in oncology care
Clinical journal of oncology nursing, ISSN: 1538067X 10921095
Suzanne McMullen; Shelagh Szabo; Ronald J. Halbert; Catherine Lai; Aparna R. Parikh; Mikele M. Bunce; Raya Khoury; Anthony Masaquel
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Dying cells actively regulate adaptive immune responses
Nature Reviews Immunology, ISSN: 14741741 14741733
Nader Yatim; Sean P. Cullen; Matthew L. Albert
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Effect of Omalizumab on Blood Basophil Counts in Patients with Chronic Idiopathic/Spontaneous Urticaria
Journal of Investigative Dermatology, ISSN: 15231747 0022202X
Sarbjit S. Saini; Theodore A. Omachi; Benjamin L. Trzaskoma; Henry N. Hulter; Karin Rosén; Patricia M. Sterba; Jean-Paul Courneya; Alan Lackey; Hubert Chen
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Reversible phosphorylation of the 26S proteasome
Protein and Cell, ISSN: 16748018 1674800X
Xing Guo; Xiuliang Huang; Mark J. Chen
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From basic apoptosis discoveries to advanced selective BCL-2 family inhibitors
Nature Reviews Drug Discovery, ISSN: 14741784 14741776
Avi Ashkenazi; Wayne J. Fairbrother; Joel D. Leverson; Andrew J. Souers
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Control Strategies for Drug Product Continuous Direct Compression—State of Control, Product Collection Strategies, and Startup/Shutdown Operations for the Production of Clinical Trial Materials and Commercial Products
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Ahmad Almaya; Lawrence De Belder; Robert Meyer; Karthik Nagapudi; Hung-Ren Homer Lin; Ian Leavesley; Jayanthy Jayanth; Gurjit Bajwa; James DiNunzio; Anthony Tantuccio; Dan Blackwood; Admassu Abebe
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Recent Insights into the Molecular Mechanisms Underlying Pyroptosis and Gasdermin Family Functions
Trends in Immunology, ISSN: 14714981 14714906
Robin A. Aglietti; Erin C. Dueber
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Characterization of PD-L1 expression and immune cell infiltration in nasopharyngeal cancer
Oral Oncology, ISSN: 18790593 13688375
Oscar Siu Hong Chan; Marcin Kowanetz; Wai Tong Ng; Koeppen; Lai Kwan Chan; Rebecca Mei Wan Yeung; Haiyan Wu; Lukas Amler; Christoph Mancao
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Challenges in Determining Intrinsic Viscosity Under Low Ionic Strength Solution Conditions
Pharmaceutical Research, ISSN: 1573904X 07248741
Mariya Pindrus; Steven J. Shire; Sandeep Yadav; Devendra S. Kalonia
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Newly diagnosed vs. relapsing giant cell arteritis: Baseline data from the GiACTA trial
Seminars in Arthritis and Rheumatism, ISSN: 1532866X 00490172
Katie Tuckwell; Neil Collinson; Sophie Dimonaco; Micki Klearman; Daniel Blockmans; Elisabeth Brouwer; Maria C. Cid; Bhaskar Dasgupta; Juergen Rech; Carlo Salvarani; Sebastian Unizony; John H. Stone
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Incidence of outcomes potentially associated with corticosteroid therapy in patients with giant cell arteritis
Seminars in Arthritis and Rheumatism, ISSN: 1532866X 00490172
Jessica C. Wilson; Khaled Sarsour; Neil Collinson; Katie Tuckwell; David Musselman; Micki Klearman; Pavel Napalkov; Susan S. Jick; John H. Stone; Christoph R. Meier
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Two-stage winner designs for non-inferiority trials with pre-specified non-inferiority margin
Journal of Statistical Planning and Inference, ISSN: 03783758
Pin-Wen Wang; Shou-En Lu; Yong Lin; Weichung J. Shih; K.K. Gordon Lan
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Single-cell RNA sequencing identifies distinct mouse medial ganglionic eminence cell types
Scientific Reports, ISSN: 20452322
Ying-Jiun J. Chen; Brad A. Friedman; Connie Ha; Durinck; Jinfeng Liu; John L. R. Rubenstein; Somasekar Seshagiri; Zora Modrusan
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T cell costimulatory receptor CD28 is a primary target for PD-1-mediated inhibition
Science, ISSN: 10959203 00368075
Enfu Hui; Jeanne Cheung; Jing Zhu; Xiaolei Su; Marcus J. Taylor; Heidi J. A. Wallweber; Dibyendu K. Sasmal; Jun Huang; Kim; Ira Mellman; Ronald D. Vale
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A distinct role for Lgr5 + stem cells in primary and metastatic colon cancer
Nature, ISSN: 14764687 00280836
Felipe de Sousa e Melo; Antonina V. Kurtova; Jonathan M. Harnoss; Noelyn Kljavin; Joerg D. Hoeck; Jeffrey Hung; Jeffrey Eastham-Anderson; Elaine E. Storm; Zora Modrusan; Koeppen; Gerrit J. P. Dijkgraaf; Robert Piskol; Frederic J. De Sauvage
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Increased autophagy-related 5 gene expression is associated with collagen expression in the airways of refractory asthmatics
Frontiers in Immunology, ISSN: 16643224
Audrey H. Poon; David F. Choy; Fazila Chouiali; Rakhee K. Ramakrishnan; Bassam Mahboub; Séverine Audusseau; Andrea Mogas; Harris; Joseph R. Arron; Catherine Laprise; Qutayba Hamid
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Development of the Regiodivergent Asymmetric Prenylation of 3-Substituted Oxindoles
Chemistry - A European Journal, ISSN: 15213765 09476539
Barry M. Trost; Walter H. Chan; Sushant Malhotra
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Development of a Practical Synthesis of ERK Inhibitor GDC-0994
Organic Process Research and Development, ISSN: 1520586X 10836160
Xin Linghu; Nicholas Wong; Hans Iding; Vera Jost; Haiming Zhang; Stefan G. Koenig; C. Gregory Sowell; Francis Gosselin
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A new cancer ecosystem
Science, ISSN: 10959203 00368075
Sandra J. Horning
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Constitutive NOTCH3 signaling promotes the growth of basal breast cancers
Cancer Research, ISSN: 15387445 00085472
Lisa Choy; Thijs Hagenbeek; Margaret Solon; French; David Finkle; Amy Shelton; Rayna Venook; Matthew J. Brauer; Christian W. Siebel
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A rational approach towards development of amorphous solid dispersions: Experimental and computational techniques
International Journal of Pharmaceutics, ISSN: 18733476 03785173
Paroma Chakravarty; Joseph W. Lubach; Jonathan Hau; Karthik Nagapudi
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Endothelial Notch1 Activity Facilitates Metastasis
Cancer Cell, ISSN: 18783686 15356108
Elfriede Wieland; Juan Rodriguez-Vita; Sven S. Liebler; Carolin Mogler; Iris Moll; Stefanie E. Herberich; Elisa Espinet; Esther Herpel; Amitai Menuchin; Jenny Chang-Claude; Michael Hoffmeister; Christoffer Gebhardt; Hermann Brenner; Andreas Trumpp; Christian W. Siebel; Markus Hecker; Jochen Utikal; David Sprinzak; Andreas Fischer
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Membrane-Proximal Epitope Facilitates Efficient T Cell Synapse Formation by Anti-FcRH5/CD3 and Is a Requirement for Myeloma Cell Killing
Cancer Cell, ISSN: 18783686 15356108
Ji Li; Nicola J. Stagg; Jennifer A. Johnston; Michael J. Harris; Sam A. Menzies; Danielle DiCara; Vanessa Clark; Maria Hristopoulos; Ryan Cook; Dionysos S. Slaga; Rin Nakamura; Luke McCarty; Siddharth Sukumaran; Luis; Zhengmao Ye; Thomas D Wu; Teiko Sumiyoshi; Dimitry Danilenko; Genee Y. Lee; Klara Totpal; Diego Ellerman; Isidro Hötzel; John R. James; Teemu T. Junttila
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BACE1 across species: A comparison of the in vivo consequences of BACE1 deletion in mice and rats
Scientific Reports, ISSN: 20452322
Martin Weber; Tiffany Wu; William J. Meilandt; Sara L. Dominguez; Hilda Solanoy; Janice Maloney; Hai Ngu; Miriam Baca; Chung Kung; Lisa Lima; Timothy K. Earr; Daniel Fleck; Shannon D. Shields; William F. Forrest; Oded Foreman; Søren Warming; Ryan J. Watts; Kimberly Scearce-Levie
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The Repertoire Dissimilarity Index as a method to compare lymphocyte receptor repertoires
BMC Bioinformatics, ISSN: 14712105
Christopher R. Bolen; Florian Rubelt; Jason A. Vander Heiden; Mark M. Davis
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Macrophage Death following Influenza Vaccination Initiates the Inflammatory Response that Promotes Dendritic Cell Function in the Draining Lymph Node
Cell Reports, ISSN: 22111247
Nikolaos Chatziandreou; Yagmur Farsakoglu; Miguel Palomino-Segura; Rocco D'Antuono; Diego Ulisse Pizzagalli; Federica Sallusto; Veronika Lukacs-Kornek; Mariagrazia Uguccioni; Davide Corti; Shannon J. Turley; Antonio Lanzavecchia; Michael C. Carroll; Santiago F. Gonzalez
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Antibody purification: Drivers of change
Process Scale Purification of Antibodies: Second Edition,
Narahari Pujar; Duncan Low; O'Leary
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Transcriptional determinants of tolerogenic and immunogenic states during dendritic cell maturation
Journal of Cell Biology, ISSN: 15408140
Bryan Vander Lugt; Jeremy Riddell; Aly A. Khan; Jason A. Hackney; Justin Lesch; Jason Devoss; Matthew T. Weirauch; Harinder Singh; Ira Mellman
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