Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 15051 - 15100 OF 15676 RESULTS

April 1, 1988

Suppression of immune cell function in vitro by recombinant human transforming growth factor-β

Cellular Immunology, ISSN: 10902163 00088749

Shalaby; Arthur J. Ammann

April 1, 1988

Tumor necrosis factor α/cachectin is a growth factor for thymocytes: Synergistic interactions with other cytokines

Journal of Experimental Medicine, ISSN: 15409538 00221007

Ranges; Albert Zlotnik; Espevik; Dinarello; Cerami; Michael A. Palladino

March 30, 1988

Activin stimulates secretion of follicle-stimulating hormone from pituitary cells desensitized to gonadotropin-releasing hormone

Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X

Ralph H. Schwall; Szonyi; Anthony J. Mason; Nikolics

March 11, 1988

Insulin-dependent diabetes mellitus induced in transgenic mice by ectopic expression of class II MHC and interferon-gamma

Cell, ISSN: 00928674

Sarvetnick; Liggitt; Pitts; Hansen; Stewart

March 11, 1988

Expression of the plasmid-encoded type I dihydrofolate reductase gene in cultured mammalian cells: A novel selectable marker

Nucleic Acids Research, ISSN: 03051048

Simonsen; Walter; Levinson

March 1, 1988

Immunopathogenesis of pediatric acquired immunodeficiency syndrome.

Journal of Perinatology, ISSN: 07438346

Arthur J. Ammann

March 1, 1988

Photoaffinity Labeling of Pituitary GnRH Receptors: Significance of the Position of Photolabel on the Ligand

Biochemistry, ISSN: 15204995 00062960

Nikolics; Szonyi; Ramachandran

February 29, 1988

Molecular cloning and amino acid sequence of human enkephalinase (neutral endopeptidase)

FEBS Letters, ISSN: 00145793

Bernard Malfroy; Wun-Jing Kuang; Peter H. Seeburg; Anthony J. Mason; Peter R. Schofield

February 15, 1988

Co-localization of the nerve growth factor precursor protein and mRNA in the mouse submandibular gland

Neuroscience Letters, ISSN: 03043940

Eleni Dicou; James Lee; Philippe Brachet

February 1, 1988

The determination of recombinant human tissue-type plasminogen activator activity by turbidimetry using a microcentrifugal analyzer

Analytical Biochemistry, ISSN: 10960309 00032697

Ronald H. Carlson; Robert L. Garnick; Andrew J.S. Jones; Meunier

January 1, 1988

Sequence and functional expression of the GABAA receptor shows a ligand-gated receptor super-family

Nature, ISSN: 00280836

Peter R. Schofield; Mark G. Darlison; Norihisa Fujita; David R. Burt; F. Anne Stephenson; Rodriguez; Lucy M. Rhee; Ramachandran; Vincenzina Reale; Thora A. Glencorse; Peter H. Seeburg; Eric A. Barnard

January 1, 1988

A single receptor binds both insulin-like growth factor II and mannose-6-phosphate

Science, ISSN: 00368075

Richard G. Macdonald; Suzanne R. Pfeffer; Lisa Coussens; Mark A. Tepper; Carol M. Brocklebank; John E. Mole; Jacqueline K. Anderson; Ellson Y. Chen; Michael P. Czech; Axel Ullrich

January 1, 1988

Chromosomal mapping of the gene for the type II insulin-like growth factor receptor/cation-independent mannose 6-phosphate receptor in man and mouse

Genomics, ISSN: 10898646 08887543

Geneviève Laureys; Barton; Axel Ullrich; Uta Francke

January 1, 1988

Recombinant expression and characterization of human activin a

Molecular Endocrinology, ISSN: 19449917 08888809

Ralph H. Schwall; Nikolics; Szonyi; Cornelia M. Gorman; Anthony J. Mason

January 1, 1988

Yeast: An experimental organism for modern biology

Science, ISSN: 00368075

David Botstein; Gerald R. Fink

January 1, 1988

Dissecting the catalytic triad of a serine protease

Nature, ISSN: 00280836

Paul J. Carter; James A. Wells

January 1, 1988

Subtilisin - an enzyme designed to be engineered

Trends in Biochemical Sciences, ISSN: 09680004

James A. Wells; David A. Estell

January 1, 1988

Antenatal serum levels of relaxin in patients having preterm labour

British Journal of Obstetrics and Gynaecology, ISSN: 14710528 14700328

Robin J. Bell; Lawrence W. Eddie; Arlene R. Lester; E.Carl Wood; Paul D. Johnston; Hugh D. Niall

January 1, 1988

Membrane guanylate cyclase is a cell-surface receptor with homology to protein kinases

Nature, ISSN: 00280836

Singh; David G Lowe; David S. Thorpe; Rodriguez; Wun-Jing Kuang; Lawrence J. Dangott; Michael Chinkers; David V. Goeddel; Garbers

January 1, 1988

Tertiary structure is a principal determinant to protein deamidaton

Science, ISSN: 00368075

Anthony A. Kossiakoff

January 1, 1988

Production and auto-induction of transforming growth factor-α in human keratinocytes

Nature, ISSN: 00280836

Robert J. Coffey; Rik Derynck; Josiah N. Wilcox; Timothy S. Bringman; A. Scott Goustin; Moses; Mark R. Pittelkow

January 1, 1988

Structural and functional basis for GABAA receptor heterogeneity

Nature, ISSN: 00280836

Edwin S. Levitan; Peter R. Schofield; David R. Burt; Lucy M. Rhee; William Wisden; Martin Köhler; Norihisa Fujita; Rodriguez; Anne Stephenson; Mark G. Darlison; Eric A. Barnard; Peter H. Seeburg

January 1, 1988

Protein products from yeast.

Biochemical Society Transactions, ISSN: 03005127

Ronald A. Hitzeman; Chung N. Chang; Christina Y. Chen; Arjun Singh; Etcheverry; Chisholm; William J. Kohr; Gordon A. Vehar; Renz; Dowbenko

January 1, 1988

Cloning and expression of the growth hormone-dependent insulin-like growth factor-binding protein

Molecular Endocrinology, ISSN: 19449917 08888809

William I. Wood; Cachianes; William J. Henzel; Genine Winslow; Steven A. Spencer; Renate Hellmiss; Martin; Baxter

January 1, 1988

Human immunodeficiency virus infections in infants and children.

Advances in pediatric infectious diseases, ISSN: 08849404

Arthur J. Ammann

January 1, 1988

The use of neutrons to show how proteins work.

Basic life sciences, ISSN: 00905542

Anthony A. Kossiakoff

January 1, 1988

A new type of transforming growth factor-beta, TGF-beta 3.

EMBO Journal, ISSN: 02614189

Rik Derynck; Patricia B. Lindquist; Angela Lee; Duanzhi Wen; Tamm; Graycar; Lucy M. Rhee; Anthony J. Mason; Duncan A. Miller; Robert J. Coffey

January 1, 1988

Functional role of muscarinic acetylcholine receptor subtype diversity

Cold Spring Harbor Symposia on Quantitative Biology, ISSN: 00917451

Avi Ashkenazi; Ernest G. Peralta; Winslow; Ramachandran; Capon

January 1, 1988

Localization of Bacillus subtilis sacU(Hy) mutations to two linked genes with similarities to the conserved procaryotic family of two-component signalling systems.

Journal of Bacteriology, ISSN: 00219193

Henner; Yang; Ferrari

January 1, 1988

Multiple early transcripts and splicing of the Autographa californica nuclear polyhedrosis virus IE-1 gene.

Journal of Virology, ISSN: 0022538X

Chisholm; Henner

January 1, 1988

Active immunoglobulin fragments synthesized in E.Coti—from Fab to scantibodies

Protein Engineering, ISSN: 17410134 17410126

Wetzel

January 1, 1988

Amplified expression of the HER2/ERBB2 oncogene induces resistance to tumor necrosis factor alpha in NIH 3T3 cells.

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Hudziak; Gail D. Lewis; Shalaby; Eessalu; Aggarwal; Axel Ullrich; Shepard

January 1, 1988

The three-dimensional structure of Bacillus amyloliquefaciens subtilisin at 1.8 A and an analysis of the structural consequences of peroxide inactivation.

Journal of Biological Chemistry, ISSN: 00219258

Bott; Ultsch; Anthony A. Kossiakoff; Graycar; Katz; Power

January 1, 1988

Rabbit liver growth hormone receptor and serum binding protein. Purification, characterization, and sequence.

Journal of Biological Chemistry, ISSN: 00219258

Steven A. Spencer; R. Glenn Hammonds; William J. Henzel; Rodriguez; Michael J. Waters; William I. Wood

January 1, 1988

Signal transduction in cells following binding of chemoattractants to membrane receptors

Virchows Archiv B Cell Pathology Including Molecular Pathology, ISSN: 03406075

Susan B. Dillon; Margrith W. Verghese; Ralph Snyderman

January 1, 1988

The human transforming growth factor alpha promoter directs transcription initiation from a single site in the absence of a TATA sequence

Molecular and Cellular Biology, ISSN: 02707306

Jakobovitis; Schlokat; Vannice; Rik Derynck; Levinson

January 1, 1988

Pharmacokinetics and tissue distribution of recombinant human tumor necrosis factor-α in mice

Drug Metabolism and Disposition, ISSN: 00909556

Ferraiolo; Moore; Crase; Gribling; Wilking; Baughman

January 1, 1988

Factor VIII-bypassing activity of bovine tissue factor using the canine hemophilic model

Journal of Clinical Investigation, ISSN: 00219738

Donogh P. O'Brien; Giles; Keri M. Tate; Gordon A. Vehar

January 1, 1988

Platelet-derived growth factor mRNA detection in human atherosclerotic plaques by in situ hybridization

Journal of Clinical Investigation, ISSN: 00219738

Josiah N. Wilcox; Smith; Williams; Schwartz; Gordon

January 1, 1988

Biodisposition and catabolism of tissue-type plasminogen activator in rats and rabbits

Fibrinolysis and Proteolysis, ISSN: 02689499

Bakhit; Derf A. Lewis; Busch; Tanswell; Mohler

January 1, 1988

Expression of membrane-associated and secreted variants of gp160 of human immunodeficiency virus type 1 in vitro and in continuous cell lines

Journal of Virology, ISSN: 0022538X

Berman; Nunes; Haffar

January 1, 1988

Efficacy of recombinant glycoprotein d subunit vaccines on the development of primary, recurrent, and latent genital infections with herpes simplex virus type 2 in guinea pigs

Journal of Infectious Diseases, ISSN: 15376613 00221899

Vogt; Timothy Gregory; Lasky; Kern; Berman

January 1, 1988

High-level expression of c-H-ras1 fails to fully transform rat-1 cells

Molecular and Cellular Biology, ISSN: 02707306

Ricketts; Levinson

January 1, 1988

Three-year results of a randomized prospective trial of methionyl human growth hormone and oxandrolone in Turner syndrome

Journal of Pediatrics, ISSN: 00223476

Rosenfeld; Hintz; Ann J. Johanson; Barry M. Sherman; Jo Anne Brasel; Stephen Burstein; Chernausek; Peter G. Compton; James W. Frane; Ronald W. Gotlin; Joyce Kuntze; Barbara M. Lippe; Patrick C. Mahoney; Wayne V. Moore; Maria I. New; Saenger; Virginia Sybert

January 1, 1988

Circulatory metabolism of recombinant tissue-type plasminogen activator in monkeys and rabbits

Fibrinolysis and Proteolysis, ISSN: 02689499

Mohler; Keri M. Tate; Timothy S. Bringman; Fuller; Keyt; Gordon A. Vehar; Adair Hotchkiss

January 1, 1988

Developmental expression of transforming growth factors alpha and beta in mouse fetus

Molecular and Cellular Biology, ISSN: 02707306

Josiah N. Wilcox; Rik Derynck

January 1, 1988

Improved Buccal Delivery of Opioid Analgesics and Antagonists with Bitterless Prodrugs

Pharmaceutical Research, ISSN: 1573904X 07248741

Munir A. Hussain; Bruce J. Aungst; Christopher A. Koval; Eli Shefter

January 1, 1988

In vivo anti-tumour activity of recombinant human tumour necrosis factor-alpha against Meth-A sarcoma requires L3T4-positive T cells

Annales de l'Institut Pasteur. Immunologie, ISSN: 07692625

Michael A. Palladino; Figari

January 1, 1988

Differential regulation of PI hydrolysis and adenylyl cyclase by muscarinic receptor subtypes

Nature, ISSN: 00280836

Ernest G. Peralta; Avi Ashkenazi; Winslow; Ramachandran; Capon

January 1, 1988

Role of the red blood cell in drug metabolism

Biopharmaceutics and Drug Disposition, ISSN: 1099081X 01422782

Cossum

Join Our Team

The little things we do every day add up to big breakthroughs. Making a difference in the lives of millions starts when you make a change in yours.

Two Scientists Walk Into a Bar

Two Scientists Walk Into a Bar

Listen to our podcast, where researchers talk about their work answering the toughest questions in human biology.