Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 9951 - 10000 OF 15613 RESULTS

Netrin-1 is a novel myelin-associated inhibitor to axon growth
Journal of Neuroscience, ISSN: 02706474 02706474
Karin Löw; Maya Culbertson; Frank Bradke; Marc Tessier-Lavigne; Mark H. Tuszynski
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SAGA-mediated H2B deubiquitination controls the development of neuronal connectivity in the Drosophila visual system
EMBO Journal, ISSN: 02614189 14602075
Vikki M. Weake; Kenneth K. Lee; Sebastián Guelman; Chia-Hui Lin; Christopher Seidel; Susan M. Abmayr; Jerry L. Workman
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Dual effects of Tween 80 on protein stability
International Journal of Pharmaceutics, ISSN: 03785173
Wei Wang; Y. John Wang; Wang
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Role for lysosomal enzyme β-hexosaminidase in the control of mycobacteria infection
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424 10916490
Ingrid Chou Koo; Yamini M. Ohol; Ping Wu; J. Hiroshi Morisaki; Jeffery S. Cox; Eric J. Brown
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Construction and preclinical characterization of Fc-mGITRL for the immunotherapy of cancer
Clinical Cancer Research, ISSN: 10780432
Peisheng Hu; Robyn S. Arias; Rebecca E. Sadun; Yu-Chih Nien; Nan Zhang; Helen Sabzevari; M. E. Christine Lutsiak; Leslie A. Khawli; Alan L. Epstein
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Laboratory evolution of Escherichia coli thioredoxin for enhanced catalysis of protein oxidation in the periplasm reveals a phylogenetically conserved substrate specificity determinant
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Lluis Masip; Daniel Klein-Marcuschamer; Shu Quan; James C. A. Bardwell; George Georgiou
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Response-independent survival benefit in metastatic colorectal cancer: A comparative analysis of N9741 and AVF2107
Journal of Clinical Oncology, ISSN: 0732183X
Grothey; Eric Hedrick; Robert Mass; Somnath Sarkar; Sam Suzuki; Ramesh K. Ramanathan; Herbert Hurwitz; Richard M. Goldberg; Daniel J. Sargent
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Synthetic antibodies for specific recognition and crystallization of structured RNA
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424 10916490
Jing-Dong Ye; Valentina Tereshko; John K. Frederiksen; Akiko Koide; Frederic A. Fellouse; Sachdev S. Sidhu; Shohei Koide; Anthony A. Kossiakoff; Joseph A. Piccirilli
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Targeting FGF19 inhibits tumor growth in colon cancer xenograft and FGF19 transgenic hepatocellular carcinoma models
Oncogene, ISSN: 09509232 14765594
Luc Desnoyers; Rama Pai; Ron Ferrando; Kathy Hötzel; Tom Le; Ross; Richard A. D. Carano; Aloma L. D'Souza; Jing Qing; Iman Mohtashemi; Avi Ashkenazi; French
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Accounting for Interim Analyses in the Assessment of Program Expected Net Present Value
Therapeutic Innovation and Regulatory Science, ISSN: 21684790
Lee D. Kaiser; Jeffrey D. Helterbrand; Hal V. Barron
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Quantification of viable tumor microvascular characteristics by multispectral analysis
Magnetic Resonance in Medicine, ISSN: 15222594 07403194
Berry; Kai H. Barck; MaryAnn Go; Ross; Xiumin Wu; Simon P. Williams; Alvin Gogineni; Mary J. Cole; Nicholas Van Bruggen; Fuh; Franklin V. Peale Jr.; Napoleone Ferrara; Ross; Ralph H. Schwall; Richard A. D. Carano
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Improved health-related quality of life for patients with active rheumatoid arthritis receiving rituximab - Results of the dose-ranging assessment: International clinical evaluation of rituximab in rheumatoid arthritis (DANCER) trial
Journal of Rheumatology, ISSN: 0315162X
Philip J. Mease; Dennis A. Revicki; Jacek Szechinski; Maria Greenwald; Alan Kivitz; Leonor Barile-Fabris; Jatinderpal Kalsi; Jennifer Eames; Marjatta Leirisalo-Repo
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The effects of CYP3A4 inhibition on erlotinib pharmacokinetics: Computer-based simulation (SimCYP™) predicts in vivo metabolic inhibition
European Journal of Clinical Pharmacology, ISSN: 00316970
Ashok Rakhit; Michael P. Pantze; Scott Fettner; Hannah M. Jones; Jean-Eric Charoin; Myriam Riek; Bert L. Lum; Marta Hamilton
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In reply
Annals of Emergency Medicine, ISSN: 01960644
Andrew R. Erdman
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hADA2a and hADA3 are required for acetylation, transcriptional activity and proliferative effects of β-catenin
Cancer Biology and Therapy, ISSN: 15384047 15558576
Min Yang; Marian L. Waterman; Rainer Brachmann
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Subspecialty differences in asthma characteristics and management
Mayo Clinic Proceedings, ISSN: 00256196
Hubert Chen; Charles A. Johnson; Tmirah Haselkorn; June H. Lee; Elliot Israel
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Characterization of a complex glycoprotein whose variable metabolic clearance in humans is dependent on terminal N-acetylglucosamine content
Biologicals, ISSN: 10451056 10958320
Rodney Keck; Namita Nayak; Laura Lerner; Shanta Raju; Stacey Ma; Thomas Schreitmueller; Steven M. Chamow; Kathy Moorhouse; Claire Kotts; Andrew J.S. Jones
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Blocking vascular endothelial growth factor-A inhibits the growth of pituitary adenomas and lowers serum prolactin level in a mouse model of multiple endocrine neoplasia type 1
Clinical Cancer Research, ISSN: 10780432
Nina Korsisaari; Ross; Xiumin Wu; Marcin Kowanetz; Navneet Pal; Linda Hall; Jeffrey Eastham-Anderson; William F. Forrest; Nicholas Van Bruggen; Franklin V. Peale Jr.; Napoleone Ferrara
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Recommended changes to oncology clinical trial design: Revolution or evolution?
European Journal of Cancer, ISSN: 09598049
Ratain; Rachel W. Humphrey; Gary Gordon; Gwendolyn Fyfe; Peter C. Adamson; Thomas R. Fleming; Walter M. Stadler; Donald A. Berry; Carl C. Peck
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High CD21 expression inhibits internalization of anti-CD19 antibodies and cytotoxicity of an anti-CD19-drug conjugate
British Journal of Haematology, ISSN: 00071048 13652141
Gladys S. Ingle; Pamela Chan; J. Michael Elliott; Wesley S. Chang; Koeppen; Jean-Philippe Stephan; Suzie J. Scales
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Computational approaches for predicting causal missense mutations in cancer genome projects
Current Bioinformatics, ISSN: 15748936
Lawrence S. Hon; Joshua S. Kaminker; Zemin Zhang
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Polymorphism at the TNF superfamily gene TNFSF4 confers susceptibility to systemic lupus erythematosus
Nature Genetics, ISSN: 10614036 15461718
Deborah S. Cunninghame Graham; Robert R. Graham; Harinder Manku; Andrew K. Wong; John C. Whittaker; Patrick M. Gaffney; Kathy L. Moser; John D. Rioux; David Altshuler; Timothy W. Behrens; Timothy J. Vyse
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Genome wide screens in yeast to identify potential binding sites and target genes of DNA-binding proteins
Nucleic Acids Research, ISSN: 03051048 13624962
Jue Zeng; Jizhou Yan; Ting Wang; Deborah Mosbrook-Davis; Kyle T. Dolan; Ryan Christensen; Gary D. Stormo; David Haussler; Richard H. Lathrop; Rainer Brachmann; Shawn M. Burgess
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In vivo imaging of mucosal CD4+ T cells using single photon emission computed tomography in a murine model of colitis
Journal of Immunological Methods, ISSN: 00221759
Bittoo Kanwar; Dong Wei Gao; Andrew B. Hwang; James P. Grenert; Simon P. Williams; Benjamin Franc; Joseph M. McCune
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Ongoing sonic hedgehog signaling is required for dorsal midline formation in the developing forebrain
Developmental Neurobiology, ISSN: 19328451 1932846X
Monica Hayhurst; Bryan B. Gore; Marc Tessier-Lavigne; Susan K. McConnell
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Coordination of growth rate, cell cycle, stress response, and metabolic activity in yeast
Molecular Biology of the Cell, ISSN: 10591524
Matthew J. Brauer; Curtis Huttenhower; Edoardo M. Airoldi; Rachel Rosenstein; John C. Matese; David Gresham; Viktor M. Boer; Olga G. Troyanskaya; David Botstein
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Optimization approaches in the routine analysis of monoclonal antibodies by capillary electrophoresis
LC-GC Europe, ISSN: 14716577
Oscar Salas-Solano; Lynn Gennaro; Chantal Felten
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The proteasome inhibitor bortezomib in combination with gemcitabine and carboplatin in advanced non-small cell lung cancer: A California Cancer Consortium phase I study
Journal of Thoracic Oncology, ISSN: 15561380 15560864
Angela M. Davies; Christopher Ruel; Primo N. Lara; Derick H. Lau; Paul H. Gumerlock; Richard Bold; Stephen Shibata; Heinz-Josef Lenz; David P. Schenkein; David R. Gandara
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The business case for energy management in high-tech industries
Energy Efficiency, ISSN: 1570646X 15706478
Evan Mills; Gary Shamshoian; Michele Blazek; Phil Naughton; Robert S. Seese; William Tschudi; Dale Sartor
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Comparison of two approaches for handling missing covariates in logistic regression
Educational and Psychological Measurement, ISSN: 15523888 00131644
Chao-Ying Joanne Peng; Jin Zhu
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Randomized, Double-Masked, Sham-Controlled Trial of Ranibizumab for Neovascular Age-related Macular Degeneration: PIER Study Year 1
American Journal of Ophthalmology, ISSN: 00029394
Carl D. Regillo; David M. Brown; Prema Abraham; Huibin Yue; Tsontcho Ianchulev; Susan Schneider; Naveed Shams
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Personalized medicine complicates medical decision-making
Managed Care, ISSN: 10623388
Thomas Morrow
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Height velocity targets from the national cooperative growth study for first-year growth hormone responses in short children
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X 0021972X
Bert Bakker; James W. Frane; Henry Anhalt; Barbara M. Lippe; Rosenfeld
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Long-term safety of recombinant human growth hormone in Turner syndrome
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X 0021972X
Katrina Bolar; Andrew R. Hoffman; Thomas J. Maneatis; Barbara M. Lippe
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T-cell lymphomas in T-cell-specific Pten-deficient mice originate in the thymus
Leukemia, ISSN: 14765551 08876924
Thijs Hagenbeek; Hergen Spits
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Recently-approved sapropterin reduces phenylalanine levels
Managed Care, ISSN: 10623388
Thomas Morrow
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Compliance and persistence in pediatric and adult patients receiving growth hormone therapy
Endocrine Practice, ISSN: 1530891X
Rosenfeld; Bert Bakker
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Assessing productivity loss and activity impairment in severe or difficult-to-treat asthma
Value in Health, ISSN: 15244733 10983015
Hubert Chen; Paul D. Blanc; Mary Lou Hayden; Eugene R. Bleecker; Chawla; June H. Lee
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Insurance status and asthma-related health care utilization in patients with severe asthma
Annals of Allergy, Asthma and Immunology, ISSN: 10811206
Anju T. Peters; Julie C. Klemens; Tmirah Haselkorn; Weiss; Leslie C. Grammer; June H. Lee; Hubert Chen
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Ranibizumab for macular edema due to retinal vein occlusions: Implication of VEGF as a critical stimulator
Molecular Therapy, ISSN: 15250024 15250016
Peter A. Campochiaro; Gulnar Hafiz; Syed Mahmood Shah; Quan Dong Nguyen; Howard Ying; Diana V. Do; Edward Quinlan; Ingrid Zimmer-Galler; Julia A. Haller; Sharon D. Solomon; Jennifer U. Sung; Yasmin Hadi; Kashif A. Janjua; Nida Jawed; David F. Choy; Joseph R. Arron
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A key claudin extracellular loop domain is critical for epithelial barrier integrity
American Journal of Pathology, ISSN: 00029440
Mrsny; G. Thomas Brown; Kirsten Gerner-Smidt; Andre G. Buret; Jon B. Meddings; Quan; Michael Koval; Asma Nusrat
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Blockade of CD11a by efalizumab in psoriasis patients induces a unique state of T-cell hyporesponsiveness
Journal of Investigative Dermatology, ISSN: 15231747 0022202X
Emma Guttman-Yassky; Yulia Vugmeyster; Michelle A. Lowes; Francesca Chamian; Toyoko Kikuchi; Mark Kagen; Patricia Gilleaudeau; Edmund Lee; Brisdell Hunte; Howell; Wolfgang Dummer; Bodary; James G. Krueger
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Ranibizumab Combined With Verteporfin Photodynamic Therapy in Neovascular Age-related Macular Degeneration (FOCUS): Year 2 Results
American Journal of Ophthalmology, ISSN: 00029394
Andrew N. Antoszyk; Lisa Tuomi; Carol Chung; Angele Singh
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Ten-year outcomes following traumatic brain injury: A population-based cohort
Brain Injury, ISSN: 1362301X 02699052
Cameron; David M. Purdie; Kliewer; Rod J. McClure
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Prediction of the possibility of the second peak of drug plasma concentration time curve after iv bolus administration from the standpoint of the traditional multi-compartmental linear pharmacokinetics
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Leonid M. Berezhkovskiy
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Summary statement novel agents in the treatment of lung cancer: Fifth Cambridge conference assessing opportunities for combination therapy
Journal of Thoracic Oncology, ISSN: 15561380 15560864
Thomas J. Lynch; George R. Blumenschein; Jeff A. Engelman; Igor Espinoza-Delgado; Ramaswamy Govindan; Jeffrey H. Hanke; Nasser H. Hanna; John V. Heymach; Fred R. Hirsch; Pasi A. Jänne; Rogerio C. Lilenbaum; Ronald B. Natale; Gregory J. Riely; Lecia V. Sequist; Geoffrey I. Shapiro; Alice T. Shaw; Frances A. Shepherd; Mark A. Socinski; A Gregory Sorensen; Heather A. Wakelee; Aaron Weitzman
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Stopping replication, at the beginning
Nature Chemical Biology, ISSN: 15524469 15524450
Peter K Jackson
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Synthesis of a cross-bridged cyclam derivative for peptide conjugation and 64Cu radiolabeling
Bioconjugate Chemistry, ISSN: 10431802
C. Andrew Boswell; Celeste A. S. Regino; Kwamena E. Baidoo; Karen J. Wong; Ambika Bumb; Heng Xu; Diane E. Milenic; James A. Kelley; Christopher C. Lai; Martin W. Brechbiel
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Evaluation of hydrate-screening methods
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Yonc Cui; Erica Yao
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The Notch pathway in prostate development and cancer
Differentiation, ISSN: 14320436 03014681
Kevin G. Leong; Gao
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