Scientists / Publications

Publications

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DISPLAYING 10201 - 10250 OF 15613 RESULTS

Metabolism, pharmacokinetics, and excretion of a nonpeptidic substance P receptor antagonist, ezlopitant, in normal healthy male volunteers: Characterization of polar metabolites by chemical derivatization with dansyl chloride
Drug Metabolism and Disposition, ISSN: 00909556 1521009X
Chandra Prakash; John O'Donnell; S. Cyrus Khojasteh
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Identification of a novel glutathione conjugate of flutamide in incubations with human liver microsomes
Drug Metabolism and Disposition, ISSN: 00909556 1521009X
Ping Kang; Deepak Dalvie; Evan Smith; Sue Zhou; Alan Deese
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CanPredict: A computational tool for predicting cancer-associated missense mutations
Nucleic Acids Research, ISSN: 03051048 13624962
Joshua S. Kaminker; Yan Zhang; Colin K. Watanabe; Zemin Zhang
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A phase I/II randomized open-label multicenter trial of efalizumab, a humanized anti-CD11a, anti-LFA-1 in renal transplantation
American Journal of Transplantation, ISSN: 16006135 16006143
Vincenti; Mendez; Pescovitz; Rajagopalan; Wilkinson; Butt; Laskow; Slakey; Lorber; Jay Garg; Marvin Garovoy
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The biology and therapeutic potential of interleukin 27
Journal of Molecular Medicine, ISSN: 09462716
Marcel Batten; Nico Ghilardi
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Response [2]
Journal of Magnetic Resonance Imaging, ISSN: 10531807 15222586
Joan M. Greve; Simon P. Williams
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GeneHub-GEPIS: Digital expression profiling for normal and cancer tissues based on an integrated gene database
Nucleic Acids Research, ISSN: 03051048 13624962
Yan Zhang; Shiuh-Ming Luoh; Lawrence S. Hon; Robert Baertsch; William I. Wood; Zemin Zhang
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Secreted sulfatases Sulf1 and Sulf2 have overlapping yet essential roles in mouse neonatal survival
PLoS ONE, ISSN: 19326203
Charles R. Holst; Hani Bou-Reslan; Bryan B. Gore; Karen Wong; Deanna Grant; Sreedevi Chalasani; Richard A. D. Carano; Gretchen D. Frantz; Marc Tessier-Lavigne; Brad Bolon; French; Avi Ashkenazi
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Epigenome scans and cancer genome sequencing converge on WNK2, a kinase-independent suppressor of cell growth
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Chibo Hong; K. Scott Moorefield; Peter Jun; Kenneth D. Aldape; Samir Kharbanda; Phillips; Joseph F. Costello
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2007 highlights of advance in the pharmaceutical sciences: An American Association of Pharmaceutical Scientists (AAPS) perspective
AAPS Journal, ISSN: 15507416
Marilyn N. Martinez; Peter Bonate; Robert L. Chapman; Anne De Groot; Susan D'Souza; Naushad Ghilazi; Vivian Gray; Vishal K. Gupta; Kim Huynh-Ba; Sunil Iyer; Arya Jayatilaka; Amita Joshi; H. Thomas Karnes; Mansoor Khan; Patrick Liu; Craig Lunte; Christopher R. McCurdy; Marilyn E. Morris; Kenneth J. Norris; Phillip Ramsey; Sanjay Sehgal; Manuel Zahn
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Inhibition of VEGF-A prevents the angiogenic switch and results in increased survival of Apc+/min mice
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Nina Korsisaari; Ian Kasman; William F. Forrest; Navneet Pal; Wei Bai; Fuh; Franklin V. Peale Jr.; Ron Smits; Napoleone Ferrara
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A Core Complex of BBS Proteins Cooperates with the GTPase Rab8 to Promote Ciliary Membrane Biogenesis
Cell, ISSN: 00928674
Maxence V. Nachury; Alexander V. Loktev; Qihong Zhang; Christopher J. Westlake; Johan Peränen; Andreas Merdes; Diane C. Slusarski; Richard H. Scheller; J.Fernando Bazan; Val C. Sheffield; Peter K Jackson
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Erratum: Armed antibodies targeting the mucin repeats of the ovarian cancer antigen, MUC16, are highly efficacious in animal tumor models (Cancer Research (2007) 67, (4924-4932))
Cancer Research, ISSN: 00085472
Youjun Chen; Suzanna Clark; Wong; Yongmei Chen; Chen; Dennis; Luis; Fiona Zhong; Sheila Bheddah; Koeppen; Alvin Gogineni; Paul G. Polakis; William Mallet
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A novel inhibitor of the alternative pathway of complement reverses inflammation and bone destruction in experimental arthritis
Journal of Experimental Medicine, ISSN: 00221007 00221007
Kenneth J. Katschke Jr.; Karim Y. Helmy; Micah Steffek; Hongkang Xi; Jianping Yin; Wyne P. Lee; Gribling; Kai H. Barck; Richard A. D. Carano; Taylor; Linda Rangell; Laurie Diehl; Hass; Wiesmann; Menno Van Lookeren Campagne
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Transitioning patients from efalizumab to alternative psoriasis therapies: Findings from an open-label, multicenter, Phase IIIb study
International Journal of Dermatology, ISSN: 00119059 13654632
Alan Menter; Tiffani K. Hamilton; Darryl P. Toth; Hoi M. Leung; Graham Wetherill; Brian Hennessey; Marvin Garovoy; Paul Kwon; David M. Pariser
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Characterization of protein-protein interactions critical for poliovirus replication: Analysis of 3AB and VPg binding to the RNA-dependent RNA polymerase
Journal of Virology, ISSN: 0022538X
Daniel M. Strauss; Deborah S. Wuttke
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The soluble Wnt receptor Frizzled8CRD-hFc inhibits the growth of teratocarcinomas in vivo
Cancer Research, ISSN: 00085472
Venita I. DeAlmeida; Li Miao; James A. Ernst; Koeppen; Paul G. Polakis; Bonnee Rubinfeld
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Real-world Evaluation of Asthma Control and Treatment (REACT): Findings from a national Web-based survey
Journal of Allergy and Clinical Immunology, ISSN: 00916749
Stephen P. Peters; Craig A. Jones; Tmirah Haselkorn; David R. Mink; David J. Valacer; Weiss
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Dendritic cell vaccine hits FDA roadblock.
Managed Care, ISSN: 10623388
Thomas Morrow
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Exploring and designing protein function with restricted diversity
Current Opinion in Chemical Biology, ISSN: 13675931
Sachdev S. Sidhu; Anthony A. Kossiakoff
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Presence of methicillin resistant Staphylococcus aureus in respiratory cultures from cystic fibrosis patients is associated with lower lung function
Pediatric Pulmonology, ISSN: 87556863 10990496
Clement L. Ren; Morgan; Michael W. Konstan; Michael S. Schechter; Wagener; Kathryn A. Fisher; Warren E. Regelmann
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Do deaf and hard of hearing youth need antitobacco education?
American Annals of the Deaf, ISSN: 0002726X
Barbara A. Herman; Leanne Streja; Coen A. Bernaards; Elizabeth A. Eckhardt; Heidi B. Kleiger; Lauren Maucere; Glenn Wong; Shari Barkin; Roshan Bastani
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A pilot study of tumor necrosis factor inhibition in erosive/inflammatory osteoarthritis of the hands
Journal of Rheumatology, ISSN: 0315162X
Molly D. Magnano; Eliza F. Chakravarty; Corrie Broudy; Lorinda Chung; Ariella Kelman; Jennifer Hillygus; Mark C. Genovese
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Nerve growth factor mediates steroid-resistant inflammation in respiratory syncytial virus infection
Pediatric Pulmonology, ISSN: 87556863 10990496
Lida Mohtasham; Alexander Auais; Giovanni Piedimonte
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Association of control and risk of severe asthma-related events in severe or difficult-to-treat asthma patients
Allergy: European Journal of Allergy and Clinical Immunology, ISSN: 01054538 13989995
Sean D. Sullivan; Sally E. Wenzel; Bresnahan; Zheng; June H. Lee; Pritchard; Tripthi V. Kamath; Weiss
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Identifying specificity profiles for peptide recognition modules from phage-displayed peptide libraries
Nature Protocols, ISSN: 17542189 17502799
Raffi Tonikian; Yingnan Zhang; Charles Boone; Sachdev S. Sidhu
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Safety outcomes of Alteplase among acute ischemic stroke patients with special characteristics
Neurocritical Care, ISSN: 15416933
Sylaja; Wei Dong; James C. Grotta; Mary K. Miller; Kristen Tomita; Scott Hamilton; Charles P. Semba; Michael D. Hill
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Structure of the catalytic domain of human polo-like kinase 1
Biochemistry, ISSN: 00062960
Michael Kothe; Darcy Kohls; Simon Low; Rocco Coli; Alan C. Cheng; Suzanne L. Jacques; Theresa L. Johnson; Lewis; Christine Loh; Jim Nonomiya; Alissa L. Sheils; Kimberly A. Verdries; Thomas A. Wynn; Cyrille Kuhn; Yuan-Hua Ding
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Armed antibodies targeting the mucin repeats of the ovarian cancer antigen, MUC16, are highly efficacious in animal tumor models
Cancer Research, ISSN: 00085472
Youjun Chen; Suzanna Clark; Wong; Yongmei Chen; Chen; Dennis; Luis; Fiona Zhong; Sheila Bheddah; Koeppen; Alvin Gogineni; Paul G. Polakis; William Mallet
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Targeting VEGF-A to treat cancer and age-related macular degeneration
Annual Review of Medicine, ISSN: 00664219
Napoleone Ferrara; Robert Mass; Claudio Campa; Robert Kim
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Full-length antibodies on display
Nature Biotechnology, ISSN: 10870156 15461696
Sachdev S. Sidhu
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Demographic and clinical characteristics of children and adolescents with severe or difficult-to-treat asthma
Journal of Allergy and Clinical Immunology, ISSN: 00916749
Bradley E. Chipps; Stanley J. Szefler; F. Estelle R. Simons; Tmirah Haselkorn; David R. Mink; Yamo Deniz; June H. Lee
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Selective clearance of glycoforms of a complex glycoprotein pharmaceutical caused by terminal N-acetylglucosamine is similar in humans and cynomolgus monkeys
Glycobiology, ISSN: 09596658 14602423
Andrew J.S. Jones; Damon I. Papac; Chin; Rodney Keck; Sharon A. Baughman; Yvonne S. Lin; Johannes Kneer; John E. Battersby
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Monoclonal antibody now available to prevent red blood cell breakdown.
Managed Care, ISSN: 10623388
Thomas Morrow
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Quantitative translational pharmacology for monoclonal antibody dose and dose-schedule determination
American Pharmaceutical Review, ISSN: 10998012
Nelson L'ntshotsholé Jumbe
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Targeted and untargeted CD137L fusion proteins for the immunotherapy of experimental solid tumors
Clinical Cancer Research, ISSN: 10780432
Nan Zhang; Rebecca E. Sadun; Robyn S. Arias; Meg L. Flanagan; Suzanne M. Sachsman; Yu-Chih Nien; Leslie A. Khawli; Peisheng Hu; Alan L. Epstein
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Loop anchor modification causes the population of an alternative native state in an SH3-like domain
Protein Science, ISSN: 09618368 1469896X
Jane A. Knappenberger; Juliette T.J. Lecomte
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Krüppel-like transcription factor 13 regulates T lymphocyte survival in vivo
Journal of Immunology, ISSN: 00221767
Meixia Zhou; Lisa McPherson; Dongdong Feng; An Song; Chen Dong; Shu-Chen Lye; Lu Zhou; Xiaoyan Shi; Yong-Tae Ahn; Demin Wang; Carol Clayberger; Alan M. Krensky
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Quantifying the treatment effect explained by markers in the presence of measurement error
Statistics in Medicine, ISSN: 02776715 10970258
Somnath Sarkar; Yongming Qu
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Role for Msh5 in the regulation of Ig class switch recombination
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Hideharu Sekine; Ricardo C. Ferreira; Qiang Pan-Hammarström; Robert R. Graham; Beth Ziemba; Sandra S. De Vries; Jiabin Liu; Keli Hippen; Thearith Koeuth; Ward Ortmann; Akiko Iwahori; Margaret K. Elliott; Steven Offer; Cara Skon; Likun Du; Jill Novitzke; Annette T. Lee; Nianxi Zhao; Joshua D. Tompkins; David Altshuler; Peter K. Gregersen; Charlotte Cunningham-Rundles; Reuben S. Harris; Chengtao Her; David L. Nelson; Lennart Hammarström; Gary S. Gilkeson; Timothy W. Behrens
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The BH3-Only Protein Bid Is Dispensable for DNA Damage- and Replicative Stress-Induced Apoptosis or Cell-Cycle Arrest
Cell, ISSN: 00928674
Kaufmann; Lin Tai; Paul G. Ekert; David C.S. Huang; Fiona Norris; Ralph K. Lindemann; Ricky W. Johnstone; Vishva M. Dixit; Andreas Strasser
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Spectroscopic evaluation of the stabilization of humanized monoclonal antibodies in amino acid formulations
International Journal of Pharmaceutics, ISSN: 03785173
Fei Tian; C. Russell Middaugh; Tom Offerdahl; Eric Munson; Samir Sane; J. Howard Rytting
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Netrin-1/DCC signaling in commissural axon guidance requires cell-autonomous expression of heparan sulfate
Journal of Neuroscience, ISSN: 02706474 02706474
Yoshihiro Matsumoto; Fumitoshi Irie; Masaru Inatani; Marc Tessier-Lavigne; Yu Yamaguchi
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ElaD, a deubiquitinating protease expressed by E. coli
PLoS ONE, ISSN: 19326203
André Catic; Shahram Misaghi; Gregory A. Korbel; Hidde L. Ploegh
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Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Robert R. Graham; Chieko Kyogoku; Snaevar Sigurdsson; Irina A. Vlasova; Leela R. L. Davies; Emily C. Baechler; Robert M. Plenge; Thearith Koeuth; Ward Ortmann; Geoffrey Hom; Jason W. Bauer; Clarence Gillett; Noel Burtt; Deborah S. Cunninghame Graham; Robert Onofrio; Michelle Petri; Iva Gunnarsson; Elisabet Svenungsson; Lars Rönnblom; Gunnel Nordmark; Peter K. Gregersen; Kathy L. Moser; Patrick M. Gaffney; Lindsey A. Criswell; Timothy J. Vyse; Ann-Christine Syvänen; Paul R. Bohjanen; Mark J. Daly; Timothy W. Behrens; David Altshuler
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Ala657 and conserved active site residues promote fibroblast activation protein endopeptidase activity via distinct mechanisms of transition state stabilization
Biochemistry, ISSN: 00062960
Sarah A. Meadows; Conrad Yap Edosada; Mark Mayeda; Thuy Tran; Quan; Helga Raab; Wiesmann; Beni B. Wolf
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Assays for the Release of Viral Vector Gene Therapy Products for Human Clinical Trials
Concepts in Genetic Medicine,
Flavia Borellini
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The tumour-suppressor Scribble dictates cell polarity during directed epithelial migration: Regulation of Rho GTPase recruitment to the leading edge
Oncogene, ISSN: 09509232 14765594
Dow; Kauffman; Caddy; Andrew S. Peterson; Jane; Russell; Humbert
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Plexin-B2 controls the development of cerebellar granule cells
Journal of Neuroscience, ISSN: 02706474 02706474
Roland H. Friedel; Géraldine Kerjan; Helen Rayburn; Ulrich Schüller; Constantino Sotelo; Marc Tessier-Lavigne; Alain Chedotal
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Glycosylphosphatidylinositol-Anchored High-Density Lipoprotein-Binding Protein 1 Plays a Critical Role in the Lipolytic Processing of Chylomicrons
Cell Metabolism, ISSN: 15504131
Anne P. Beigneux; Brandon S.J. Davies; Peter Gin; Michael M. Weinstein; Emily Farber; Xin Qiao; Franklin V. Peale Jr.; Bunting; Rosemary L. Walzem; Jinny S. Wong; William S. Blaner; Zhi-Ming Ding; Kristan Melford; Nuttaporn Wongsiriroj; Xiao Shu; Frederic J. De Sauvage; Robert O. Ryan; Loren G. Fong; André Bensadoun; Stephen G. Young
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