Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 10301 - 10350 OF 15613 RESULTS

February 1, 2007

A promising theory stumbles in clinical trials.

Managed Care, ISSN: 10623388

Thomas Morrow

February 1, 2007

Putting Transcription Repression and Protein Destruction in pRb's Pocket

Developmental Cell, ISSN: 15345807

Emmy W. Verschuren; Peter K Jackson

February 1, 2007

pH transients during salt removal in isoelectric trapping separations: A curse revisited

Electrophoresis, ISSN: 01730835 15222683

Evan Shave; Gyula Vigh

February 1, 2007

Endothelium-Microenvironment Interactions in the Developing Embryo and in the Adult

Developmental Cell, ISSN: 15345807

Kristy Red-Horse; Yongping Crawford; Farbod Shojaei; Napoleone Ferrara

February 1, 2007

The many ways of Wnt in cancer

Current Opinion in Genetics and Development, ISSN: 0959437X

Paul G. Polakis

February 1, 2007

Erlotinib directly inhibits HER2 kinase activation and downstream signaling events in intact cells lacking epidermal growth factor receptor expression

Cancer Research, ISSN: 00085472

Gabriele Schaefer; Lily Shao; Klara Totpal; Robert W. Akita

February 1, 2007

Pattern recognition of sleep in rodents using piezoelectric signals generated by gross body movements

IEEE Transactions on Biomedical Engineering, ISSN: 00189294

Aaron E. Flores; Judith E. Flores; Hrishikesh Deshpande; Jorge A. Picazo; Xinmin Xie; Paul Franken; H. Craig Heller; Dennis A. Grahn; Bruce F. O'Hara

February 1, 2007

Subgroup Analysis of the MARINA Study of Ranibizumab in Neovascular Age-Related Macular Degeneration

Ophthalmology, ISSN: 01616420

David S. Boyer; Andrew N. Antoszyk; Carl C. Awh; Robert B. Bhisitkul; Howard Shapiro; Nisha R. Acharya

January 23, 2007

Identification of Rab11 as a small GTPase binding protein for the Evi5 oncogene

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Christopher J. Westlake; Jagath R. Junutula; Glenn C. Simon; Manohar Pilli; Rytis Prekeris; Richard H. Scheller; Peter K Jackson; Adam G. Eldridge

January 22, 2007

IL-25 regulates Th17 function in autoimmune inflammation

Journal of Experimental Medicine, ISSN: 00221007 00221007

Melanie A. Kleinschek; Alexander M. Owyang; Barbara Joyce-Shaikh; Claire L. Langrish; Yi Chen; Daniel M. Gorman; Wendy M. Blumenschein; Terrill McClanahan; Frank Brombacher; Stephen D. Hurst; Robert A. Kastelein; Daniel J. Cua

January 19, 2007

FBXO11 promotes the neddylation of p53 and inhibits its transcriptional activity

Journal of Biological Chemistry, ISSN: 00219258 1083351X

Wassim M. Abida; Anatoly Nikolaev; Wenhui Zhao; Wenzhu Zhang; Wei Gu

January 15, 2007

Distinguishing cancer-associated missense mutations from common polymorphisms

Cancer Research, ISSN: 00085472

Joshua S. Kaminker; Yan Zhang; Allison Waugh; Matthias Peter; Brock A. Peters; Dragan Sebisanovic; Stinson; William F. Forrest; J.Fernando Bazan; Somasekar Seshagiri; Zemin Zhang

January 1, 2007

Strategies for successful lyophilization process scale-up

American Pharmaceutical Review, ISSN: 10998012

Samir Sane; Chung C. Hsu

January 1, 2007

Validation of analytical procedures and physical methods

Validation of Pharmaceutical Processes, Third Edition,

Hélène Gazzano-Santoro; Broughton; Dieter Schmalzing

January 1, 2007

Protein NMR Spectroscopy

Protein NMR Spectroscopy,

John Cavanagh; Wayne J. Fairbrother; Arthur G. Palmer III; Nicholas J. Skelton; Mark Rance

January 1, 2007

Natural Killer or Dendritic: What's in a Name?

Immunity, ISSN: 10747613

Hergen Spits; Lewis L. Lanier

January 1, 2007

Is Hydroxocobalamin Safe and Effective for Smoke Inhalation? Searching for Guidance in the Haze

Annals of Emergency Medicine, ISSN: 01960644

Andrew R. Erdman

January 1, 2007

Ubiquitination screen using protein microarrays for comprehensive identification of Rsp5 substrates in yeast

Molecular Systems Biology, ISSN: 17444292 17444292

Ronish Gupta; Bart Kus; Christopher Fladd; James Wasmuth; Raffi Tonikian; Sachdev S. Sidhu; Nevan J. Krogan; John Parkinson; Daniela Rotin

January 1, 2007

Inflammasome adaptors and sensors: Intracellular regulators of infection and inflammation

Nature Reviews Immunology, ISSN: 14741733

Sanjeev Mariathasan; Denise M. Monack

January 1, 2007

Streptolysin O enhances keratinocyte migration and proliferation and promotes skin organ culture wound healing in vitro

Wound Repair and Regeneration, ISSN: 10671927 1524475X

Marjana Tomic-Canic; Stephen W. Mamber; Olivera Stojadinovic; Brian Lee; Nadezda Radoja; John McMichael

January 1, 2007

Postnatal induction of transforming growth factor β signaling in fibroblasts of mice recapitulates clinical, histologic, and biochemical features of scleroderma

Arthritis and Rheumatism, ISSN: 00043591

Sonali Sonnylal; Christopher P. Denton; Bing Zheng; Douglas R. Keene; Ruming He; Henry P. Adams; Carolyn S. VanPelt; Yong J. Geng; Jenny M. Deng; Richard R. Behringer; Benoit De Crombrugghe

January 1, 2007

Imaging tumors with an albumin-binding Fab, a novel tumor-targeting agent

Cancer Research, ISSN: 00085472

Dennis; Hongkui Jin; Dugger; Renhui Yang; Leanne McFarland; Annie Ogasawara; Simon P. Williams; Mary J. Cole; Ross; Ralph H. Schwall

January 1, 2007

An interferon signature in the peripheral blood of dermatomyositis patients is associated with disease activity

Molecular Medicine, ISSN: 10761551

Emily C. Baechler; Jason W. Bauer; Catherine A. Slattery; Ward Ortmann; Karl J. Espe; Jill Novitzke; Steven R. Ytterberg; Peter K. Gregersen; Timothy W. Behrens; Ann M. Reed

January 1, 2007

Medication costs: The role physicians play with their senior patients

Journal of the American Geriatrics Society, ISSN: 00028614 15325415

Mary Sue Beran; Marianne Laouri; Marika Suttorp; Robert Brook

January 1, 2007

Adenoviral expression of XIAP antisense RNA induces apoptosis in glioma cells and suppresses the growth of xenografts in nude mice

Gene Therapy, ISSN: 14765462 09697128

Naumann; Bähr; Wolburg; Altenberend; Wick; Liston; Avi Ashkenazi; Michael Weller

January 1, 2007

Rapid removal of N-linked oligosaccharides using microwave assisted enzyme catalyzed deglycosylation

International Journal of Mass Spectrometry, ISSN: 13873806

Wendy N. Sandoval; Arellano; David Arnott; Helga Raab; Richard L. Vandlen; Jennie R. Lill

January 1, 2007

Moisture-induced aggregation of lyophilized DNA and its prevention

Pharmaceutical Research, ISSN: 07248741 1573904X

Vikas Sharma; Klibanov

January 1, 2007

Cell culture process development: Advances in process engineering

Biotechnology Progress, ISSN: 87567938

Carole Heath; Robert Kiss

January 1, 2007

Endpoints for agents that slow tumor growth

Contemporary Clinical Trials, ISSN: 15517144

Ron X. Yu; Holmgren

January 1, 2007

Synthetic antibodies as therapeutics

Expert Opinion on Biological Therapy, ISSN: 14712598

Fuh

January 1, 2007

Potentiation of kinesin spindle protein inhibitor-induced cell death by modulation of mitochondrial and death receptor apoptotic pathways

Cancer Research, ISSN: 00085472

Ulka Vijapurkar; Wei Wang; Ronald Herbst

January 1, 2007

Metabolic stability screen for drug discovery using cassette analysis and column switching.

Drug Metabolism Letters, ISSN: 18723128

Jason S Halladay; Susan C. Wong; Sharmin M Jaffer; Achintya K Sinhababu; S. Cyrus Khojasteh

January 1, 2007

Molecular markers in patients with chronic wounds to guide surgical debridement

Molecular Medicine, ISSN: 10761551

Harold Brem; Olivera Stojadinovic; Robert F. Diegelmann; Hyacinth Entero; Brian Lee; Irena Pastar; Michael Golinko; Harvey Rosenberg; Marjana Tomic-Canic

January 1, 2007

M13 bacteriophage coat proteins engineered for improved phage display.

Methods in Molecular Biology, ISSN: 10643745

Sachdev S. Sidhu; Birte K Feld; Gregory A. Weiss

January 1, 2007

Blocking Neuropilin-1 Function Has an Additive Effect with Anti-VEGF to Inhibit Tumor Growth

Cancer Cell, ISSN: 15356108

Qi Pan; Yvan Chanthery; Wei-Ching Liang; Scott Stawicki; Judy Mak; Nisha Rathore; Raymond K. Tong; Joe Kowalski; Sharon Fong Yee; Glenn Pacheco; Ross; Zhiyong Cheng; Jennifer Le Couter; Greg D. Plowman; Franklin V. Peale Jr.; Alexander W. Koch; Yan Wu; Anil Bagri; Marc Tessier-Lavigne; Ryan J. Watts

January 1, 2007

Expression profiling of the mouse prostate after castration and hormone replacement: Implication of H-cadherin in prostate tumorigenesis

Differentiation, ISSN: 14320436 03014681

Xi-De Wang; Bu-Er Wang; Robert Soriano; Jiping Zha; Zemin Zhang; Zora Modrusan; Gerald R. Cunha; Gao

January 1, 2007

Recent asthma exacerbations: A key predictor of future exacerbations

Respiratory Medicine, ISSN: 09546111

Mary K. Miller; June H. Lee; Dave P. Miller; Sally E. Wenzel

January 1, 2007

Mortality and reproductive dynamics of Aedes aegypti (Diptera: Culicidae) fed human blood

Vector-Borne and Zoonotic Diseases, ISSN: 15303667

Linda M. Styer; Sharon L. Minnick; Anna K. Sun; Thomas W. Scott

January 1, 2007

Probing cellular systems with chemistry

Nature Chemical Biology, ISSN: 15524469 15524450

Rami N. Hannoush

January 1, 2007

Society of Toxicologic Pathology Position Paper on Pathology Image Data: Compliance with 21 CFR Parts 58 and 11

Toxicologic Pathology, ISSN: 01926233

Darrell L. Tuomari; Ramon K. Kemp; Rani Sellers; John T. Yarrington; Frank J. Geoly; Xavier L. M. Fouillet; Noel Dybdal; Rick Perry

January 1, 2007

ABRF-PRG04: Differentiation of protein isoforms

Journal of Biomolecular Techniques, ISSN: 19434731 15240215

David Arnott; Mary Ann Gawinowicz; Jeffrey A. Kowalak; William Lane; Kaye D. Speicher; Christoph W. Turck; Karen A. West; Thomas A. Neubert

January 1, 2007

For patients with a broken hip, news of a lifetime replacement

Managed Care, ISSN: 10623388

Thomas Morrow

January 1, 2007

Oncogenic regulators and substrates of the anaphase promoting complex/cyclosome are frequently overexpressed in malignant tumors

American Journal of Pathology, ISSN: 00029440

Norman L. Lehman; Rob Tibshirani; Jerry Y. Hsu; Yasodha Natkunam; Brent T. Harris; Robert B. West; Marilyn A. Masek; Kelli Montgomery; Matt Van De Rijn; Peter K Jackson

January 1, 2007

Lym-1-induced apoptosis of non-Hodgkin's lymphomas produces regression of transplanted tumors

Cancer Biotherapy and Radiopharmaceuticals, ISSN: 10849785

Nan Zhang; Leslie A. Khawli; Peisheng Hu; Alan L. Epstein

January 1, 2007

ADDRESS (ADministration of DRotrecogin alfa [activated] in Early stage Severe Sepsis) long-term follow-up: One-year safety and efficacy evaluation

Critical Care Medicine, ISSN: 00903493

Pierre-Francois Laterre; Edward Abraham; Jonathan M. Janes; Benjamin L. Trzaskoma; Nancy L. Correll; Frank V. Booth

January 1, 2007

Fluid support worsens outcome and negates the benefit of protective antigen-directed monoclonal antibody in a lethal toxin-infused rat Bacillus anthracis shock model

Critical Care Medicine, ISSN: 00903493

Kevin Sherer; Yan Li; Xizhong Cui; Xuemei Li; Mani Subramanian; Mike Laird; Mahtab Moayeri; Stephen H. Leppla; Yvonne Fitz; Junwu Su; Peter Q. Eichacker

January 1, 2007

Cox regression methods for two-stage randomization designs

Biometrics, ISSN: 15410420 0006341X

Yuliya Lokhnygina; Jeffrey D. Helterbrand

January 1, 2007

Progressive Fibrosis in Nonalcoholic Steatohepatitis: Association With Altered Regeneration and a Ductular Reaction

Gastroenterology, ISSN: 00165085

Michelle M. Richardson; Julie R. Jonsson; Elizabeth E. Powell; Elizabeth M. Brunt; Brent A. Neuschwander-Tetri; Prithi S. Bhathal; John B. Dixon; Martin D. Weltman; Herbert Tilg; Alexander R. Moschen; David M. Purdie; Anthony J. Demetris; Andrew D. Clouston

January 1, 2007

Lack of augmentation of tumor spectrum or severity in dual heterozygous Men1 and Rb1 knockout mice

Oncogene, ISSN: 14765594 09509232

Loffler; Biondi; Gartside; Serewko-Auret; Duncan; Tonks; Mould; Waring; Muller; Kay; Hayward

January 1, 2007

Implications of pharmacogenomics in the current and future treatment of asthma

Journal of Managed Care Pharmacy, ISSN: 10834087

Thomas Morrow

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