Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 10451 - 10500 OF 15613 RESULTS

Axon guidance by diffusible chemoattractants: A gradient of netrin protein in the developing spinal cord
Journal of Neuroscience, ISSN: 02706474 02706474
Timothy E. Kennedy; Hao Wang; Wallace Marshall; Marc Tessier-Lavigne
View on Scopus
Activation of the Proapoptotic Death Receptor DR5 by Oligomeric Peptide and Antibody Agonists
Journal of Molecular Biology, ISSN: 00222836
Bing Li; Russell; Deanne M. Compaan; Klara Totpal; Scot A. Marsters; Avi Ashkenazi; Andrea G Cochran; Sarah G. Hymowitz; Sachdev S. Sidhu
View on Scopus
Kinetic analysis of epidermal growth factor receptor somatic mutant proteins shows increased sensitivity to the epidermal growth factor receptor tyrosine kinase inhibitor, erlotinib
Cancer Research, ISSN: 00085472
Kendall Carey; Andrew J. Garton; Maria Romero; Jennifer Kahler; Stuart Thomson; Ross; Frances Park; Haley; Neil Gibson; Mark X. Sliwkowski
View on Scopus
Capillary electrophoresis-mass spectrometry as a characterization tool for therapeutic proteins
Analytical Biochemistry, ISSN: 10960309 00032697
Lynn Gennaro; Oscar Salas-Solano; Stacey Ma
View on Scopus
CpG island methylator phenotype and childhood leukemia
Clinical Cancer Research, ISSN: 10780432
Norman J. Lacayo; Jorge F. DiMartino; Michael C. Wei; Gary V. Dahl
View on Scopus
Requirement for coronin 1 in T lymphocyte trafficking and cellular homeostasis
Science, ISSN: 00368075 10959203
Niko Föger; Linda Rangell; Dimitry Danilenko; Andrew A. Chan
View on Scopus
Formulation and delivery issues for monoclonal antibody therapeutics
Advanced Drug Delivery Reviews, ISSN: 0169409X
Daugherty; Mrsny
View on Scopus
Convergent and divergent ligand specificity among PDZ domains of the LAP and zonula occludens (ZO) families
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Yingnan Zhang; Sherry Yeh; Brent A. Appleton; Heike A. Held; P. Jaya Kausalya; Dominic C. Y. Phua; Wai Lee T. Wong; Lasky; Wiesmann; Walter Hunziker; Sachdev S. Sidhu
View on Scopus
Comparative structural analysis of the Erbin PDZ domain and the first PDZ domain of ZO-1 Insights into determinants of PDZ domain specificity
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Brent A. Appleton; Yingnan Zhang; Ping Wu; Jianping Yin; Walter Hunziker; Nicholas J. Skelton; Sachdev S. Sidhu; Wiesmann
View on Scopus
Comprehensive and quantitative mapping of energy landscapes for protein-protein interactions by rapid combinatorial scanning
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Gábor Pál; Jean-Louis K. Kouadio; Dean R. Artis; Anthony A. Kossiakoff; Sachdev S. Sidhu
View on Scopus
Delineation of the cell-extrinsic apoptosis pathway in the zebrafish
Cell Death and Differentiation, ISSN: 14765403 13509047
Eimon; Kratz; Eugene Varfolomeev; Sarah G. Hymowitz; Howard M. Stern; Jiping Zha; Avi Ashkenazi
View on Scopus
Functional characterization of the Bcl-2 gene family in the zebrafish
Cell Death and Differentiation, ISSN: 14765403 13509047
Kratz; Eimon; Kiran Mukhyala; Howard M. Stern; Jiping Zha; Andreas Strasser; Reece K. Hart; Avi Ashkenazi
View on Scopus
Clinical pharmacokinetics of erlotinib in patients with solid tumors and exposure-safety relationship in patients with non-small cell lung cancer
Clinical Pharmacology and Therapeutics, ISSN: 00099236
Jian-Feng Lu; Stephen M. Eppler; Julie Wolf; Marta Hamilton; Ashok Rakhit; Rene Bruno; Bert L. Lum
View on Scopus
Predicting benefit from anti-angiogenic agents in malignancy
Nature Reviews Cancer, ISSN: 1474175X
Adrian M. Jubb; Adam J. Oates; Scott N. Holden; Koeppen
View on Scopus
UNC5A promotes neuronal apoptosis during spinal cord development independent of netrin-1
Nature Neuroscience, ISSN: 10976256
Megan E. Williams; Lu; William L. McKenna; Raesha Washington; Adam Boyette; Phyllis Strickland; Dillon; Kaprielian; Marc Tessier-Lavigne; Hinck
View on Scopus
Matching patients with drugs: Triumphs and challenges
Personalized Medicine, ISSN: 17410541 1744828X
Waring
View on Scopus
The Crystal Structure of the Costimulatory OX40-OX40L Complex
Structure, ISSN: 09692126
Deanne M. Compaan; Sarah G. Hymowitz
View on Scopus
A high throughput electrochemiluminescent cell-binding assay for therapeutic anti-CD20 antibody selection
Journal of Immunological Methods, ISSN: 00221759
Yanmei Lu; Wai Lee T. Wong; Meng
View on Scopus
Developmental neurobiology: A destructive switch for neurons
Nature, ISSN: 14764687 00280836
Peter K Jackson
View on Scopus
Repressor roles for TCF-4 and Sfrp1 in Wnt signaling in breast cancer
Oncogene, ISSN: 09509232 14765594
Shulewitz; Soloviev; Thomas D Wu; Koeppen; Paul G. Polakis; Sakanaka
View on Scopus
Overexpression of the anaphase promoting complex/cyclosome inhibitor Emi1 leads to tetraploidy and genomic instability of p53-deficient cells
Cell Cycle, ISSN: 15514005 15384101
Norman L. Lehman; Emmy W. Verschuren; Jerry Y. Hsu; Athena M. Cherry; Peter K Jackson
View on Scopus
Destabilizing missense mutations in the tumour suppressor protein p53 enhance its ubiquitination in vitro and in vivo
Biochemical Journal, ISSN: 02646021
Harumi Shimizu; David Saliba; Maura Wallace; Lee Finlan; Patrick R. R. Langridge-Smith; Ted R. Hupp
View on Scopus
Interleukin 12p40 is required for dendritic cell migration and T cell priming after Mycobacterium tuberculosis infection
Journal of Experimental Medicine, ISSN: 00221007 00221007
Shabaana A. Khader; Santiago Partida-Sanchez; Guy Bell; Dawn M. Jelley-Gibbs; Susan L. Swain; John E. Pearl; Nico Ghilardi; Frederic J. De Sauvage; Frances E. Lund; Andrea M. Cooper
View on Scopus
Death-receptor activation halts clathrin-dependent endocytosis
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Cary D. Austin; David Lawrence; Andrew A. Peden; Eugene Varfolomeev; Klara Totpal; Ann De Mazière; Judith Klumperman; David Arnott; Victoria Pham; Richard H. Scheller; Avi Ashkenazi
View on Scopus
Inhibin-B levels in healthy young adult men and prepubertal boys: Is obesity the cause for the contemporary decline in sperm count because of fewer sertoli cells?
Journal of Andrology, ISSN: 01963635
Stephen J. Winters; Chenxi Wang; Eiman Abdelrahaman; Venus Hadeed; Mary Ann Dyky; Adam Brufsky
View on Scopus
Uncontrolled asthma: A review of the prevalence, disease burden and options for treatment
Respiratory Medicine, ISSN: 09546111
Stephen P. Peters; Gary Ferguson; Yamo Deniz; Colin Reisner
View on Scopus
A serum-free Vero production platform for a chimeric virus vaccine candidate
Cytotechnology, ISSN: 09209069 15730778
Inn H. Yuk; Gina B. Lin; Hui Ju; Inesse Sifi; Yvonne Lam; Armida Cortez; Danny Liebertz; J. Michael Berry; Richard M. Schwartz
View on Scopus
The pharmacokinetics of an albumin-binding Fab (AB.Fab) can be modulated as a function of affinity for albumin
Protein Engineering, Design and Selection, ISSN: 17410126 17410134
Allen Nguyen; Arthur Reyes; Min Zhang; Paul McDonald; Wai Lee T. Wong; Lisa A. Damico; Dennis
View on Scopus
Gender differences in IgE-mediated allergic asthma in the epidemiology and natural history of asthma: Outcomes and treatment regimens (TENOR) study
Journal of Asthma, ISSN: 02770903 15324303
June H. Lee; Tmirah Haselkorn; Bradley E. Chipps; Dave P. Miller; Sally E. Wenzel
View on Scopus
Wlds Protection Distinguishes Axon Degeneration following Injury from Naturally Occurring Developmental Pruning
Neuron, ISSN: 08966273
Eric D. Hoopfer; Todd McLaughlin; Ryan J. Watts; Oren Schuldiner; Dennis D.M. O'Leary; Liqun Luo
View on Scopus
Achaete-scute like 2 (ascl2) is a target of Wnt signalling and is upregulated in intestinal neoplasia
Oncogene, ISSN: 09509232 14765594
Adrian M. Jubb; Sreedevi Chalasani; Gretchen D. Frantz; Ron Smits; Grabsch; Kavi; Maughan; Kenneth J. Hillan; Philip Quirke; Koeppen
View on Scopus
Effect of Door-to-Balloon Time on Mortality in Patients With ST-Segment Elevation Myocardial Infarction
Journal of the American College of Cardiology, ISSN: 07351097
Robert L. McNamara; Yongfei Wang; Jeph Herrin; Jeptha P. Curtis; Elizabeth H. Bradley; David J. Magid; Eric D. Peterson; Martha Blaney; Paul D. Frederick; Harlan M. Krumholz
View on Scopus
Basic helix-loop-helix gene hes6 delineates the sensory hair cell lineage in the inner ear
Developmental Dynamics, ISSN: 10588388 10970177
Dong Qian; Kristen Radde-Gallwitz; Michael Kelly; Björn Tyrberg; Jaesang Kim; Gao; Ping Chen
View on Scopus
Patient-perceived impact of resective epilepsy surgery
Neurology, ISSN: 00283878
Peter Chin; Berg; Spencer; Lee; Shinnar; Sperling; Langfitt; Walczak; Pacia; Bazil; Vassar; Vickrey
View on Scopus
Rationale for fixed dosing of pertuzumab in cancer patients based on population pharmacokinetic analysis
Pharmaceutical Research, ISSN: 07248741 1573904X
Chee Ng; Bert L. Lum; Veronica Gimenez; Steve Kelsey; David E. Allison
View on Scopus
Preclinical pharmacologic evaluation of MST-997, an orally active taxane with superior in vitro and in vivo efficacy in paclitaxel- and docetaxel-resistant tumor models
Clinical Cancer Research, ISSN: 10780432
Deepak Sampath; Lee M. Greenberger; Carl Beyer; Malathi Hari; Hao Liu; Michelle Baxter; Yang Sharon; Carol Rios; Carolyn Discafani
View on Scopus
Door-to-drug and door-to-balloon times: Where can we improve? Time to reperfusion therapy in patients with ST-segment elevation myocardial infarction (STEMI)
American Heart Journal, ISSN: 00028703 10976744
Elizabeth H. Bradley; Jeph Herrin; Yongfei Wang; Robert L. McNamara; Martha J. Radford; David J. Magid; John G. Canto; Martha Blaney; Harlan M. Krumholz
View on Scopus
Deletion of exon I of SMAD7 in mice results in altered B cell responses
Journal of Immunology, ISSN: 00221767
Ronggui Li; Alexander Rosendahl; Greger Brodin; Alec M. Cheng; Aive Ahgren; Christina Sundquist; Sarang Kulkarni; Tony Pawson; Carl-Henrik Heldin; Rainer L. Heuchel
View on Scopus
Humanization of a recombinant monoclonal antibody to produce a therapeutic HER dimerization inhibitor, pertuzumab
Cancer Immunology, Immunotherapy, ISSN: 03407004
Adams; David E. Allison; Kelly Flagella; Presta; Janet Clarke; Noel Dybdal; Kathleen McKeever; Mark X. Sliwkowski
View on Scopus
B cell immunobiology in disease: Evolving concepts from the clinic
Annual Review of Immunology, ISSN: 07320582
Flavius Martin; Andrew A. Chan
View on Scopus
Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Evette S. Radisky; Justin M. Lee; Chia-Jung Karen Lu; Daniel E. Koshland Jr.
View on Scopus
De novo proteomic sequencing of a monoclonal antibody raised against OX40 ligand
Analytical Biochemistry, ISSN: 10960309 00032697
Victoria Pham; William J. Henzel; David Arnott; Sarah G. Hymowitz; Wendy N. Sandoval; Bao-Tran Truong; Henry B. Lowman; Jennie R. Lill
View on Scopus
Tumor-driven paracrine platelet-derived growth factor receptor α signaling is a key determinant of stromal cell recruitment in a model of human lung carcinoma
Clinical Cancer Research, ISSN: 10780432
Max L. Tejada; Lanlan Yu; Jianying Dong; Kenneth Jung; Meng; Franklin V. Peale Jr.; Gretchen D. Frantz; Linda Hall; Xiao Huan Liang; Hans-Peter Gerber; Napoleone Ferrara
View on Scopus
The efficacy and safety of rituximab in patients with active rheumatoid arthritis despite methotrexate treatment: Results of a phase IIb randomized, double-blind, placebo-controlled, dose-ranging trial
Arthritis and Rheumatism, ISSN: 00043591
Paul Emery; Roy Fleischmann; Anna Filipowicz-Sosnowska; Joy Schechtman; Leszek Szczepanski; Arthur Kavanaugh; Artur J. Racewicz; Ronald Van Vollenhoven; Nicole F. Li; Sunil Agarwal; Eva W. Hessey; Tim Shaw
View on Scopus
Assessing the impact of cancer: Development of a new instrument for long-term survivors
Psycho-Oncology, ISSN: 10579249 10991611
Brad J. Zebrack; Patricia A. Ganz; Coen A. Bernaards; Laura Petersen; Laura Abraham
View on Scopus
IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6
Journal of Clinical Investigation, ISSN: 00219738 15588238
David Yen; Jeanne Cheung; Heleen Scheerens; Frédérique Poulet; Terrill McClanahan; Brent Mckenzie; Melanie A. Kleinschek; Alexander M. Owyang; Jeanine Mattson; Wendy M. Blumenschein; Erin Murphy; Manjiri Sathe; Daniel J. Cua; Robert A. Kastelein; Donna Rennick
View on Scopus
The role of rituximab in the treatment of canine lymphoma: An ex vivo evaluation
Veterinary Journal, ISSN: 10900233
Joseph A Impellizeri; Howell; Kathleen McKeever; Steven E Crow
View on Scopus
Safety of efalizumab in adults with chronic moderate to severe plaque psoriasis: A phase IIIb, randomized, controlled trial
International Journal of Dermatology, ISSN: 00119059 13654632
Kim Papp; Reni Bressinck; Scott Fretzin; Bernard Goffe; Steven Kempers; Kenneth B. Gordon; Ivor Caro; Patricia Walicke; Xiaolin Wang; Alan Menter
View on Scopus
The Pre-Hospital Electrocardiogram and Time to Reperfusion in Patients With Acute Myocardial Infarction, 2000-2002. Findings From the National Registry of Myocardial Infarction-4
Journal of the American College of Cardiology, ISSN: 07351097
Jeptha P. Curtis; Edward L. Portnay; Yongfei Wang; Robert L. McNamara; Jeph Herrin; Elizabeth H. Bradley; David J. Magid; Martha Blaney; John G. Canto; Harlan M. Krumholz
View on Scopus
Comments on plasmalemmal vesicle associated protein-1 as a novel marker implicated in brain tumor angiogenesis [3]
Clinical Cancer Research, ISSN: 10780432
Laura A. Strickland; Koeppen
View on Scopus
© 2025 Genentech, Inc. All rights reserved. This site is intended for US residents only.