Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 10551 - 10600 OF 15613 RESULTS

Notch signaling is required for normal prostatic epithelial cell proliferation and differentiation
Developmental Biology, ISSN: 00121606
Xi-De Wang; Ching Ching Leow; Jiping Zha; Zhijun Tang; Zora Modrusan; Freddy Radtke; Michel Aguet; Frederic J. De Sauvage; Gao
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Ocular versus extraocular neovascularization: Mirror images or vague resemblances
Investigative Ophthalmology and Visual Science, ISSN: 01460404
Peter A. Campochiaro; Rhoda Alani; Kari Alitalo; Peter Brooks; Ruth Caldwell; Peter Carmeliet; Pier Paolo Claudio; Robert D'Amato; Arup Das; Rainer De Martin; Michael Detmar; Napoleone Ferrara; Robert N. Frank; Marcus Fruttiger; Antonio Giordano; Maria Grant; Hans-Peter Hammes; Mats Hellstrom; David Hinton; Eli Keshet; Alisa Koch; Richard Lang; Donald M. McDonald; Jeremy Nathans; Dario Neri; Gera Neufeld; Jean Plouet; Gregg Semenza; Nader Sheibani; David T. Shima; Philip Thorpe; Rubin Tuder; Olga Volpert; Elizabeth Wagner; Bernhard Weber; Stanley Wiegand
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In reply [2]
Journal of Clinical Oncology, ISSN: 0732183X
Fairooz F. Kabbinavar; Julie Hambleton; Robert Mass; Somnath Sarkar
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Oncogenic BRAF is required for tumor growth and maintenance in melanoma models
Cancer Research, ISSN: 00085472
Klaus P. Hoeflich; Daniel C. Gray; Mike Eby; Janet Y. Tien; Leo Wong; Janeko Bower; Alvin Gogineni; Jiping Zha; Mary J. Cole; Howard M. Stern; Lesley J. Murray; David P. Davis; Somasekar Seshagiri
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Redundant roles of VEGF-B and PlGF during selective VEGF-A blockade in mice
Blood, ISSN: 00064971 00064971
Ajay K. Malik; Megan E. Baldwin; Franklin V. Peale Jr.; Fuh; Wei-Ching Liang; Henry B. Lowman; Meng; Napoleone Ferrara; Hans-Peter Gerber
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When proteomes collide
Science, ISSN: 00368075 10959203
Joel S. Bader; John Chant
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Cross-species vascular endothelial growth factor (VEGF)-blocking antibodies completely inhibit the growth of human tumor xenografts and measure the contribution of stromal VEGF
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Wei-Ching Liang; Xiumin Wu; Franklin V. Peale Jr.; Chingwei V. Lee; Meng; Johnny Gutierrez; Ling Fu; Ajay K. Malik; Hans-Peter Gerber; Napoleone Ferrara; Fuh
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Impact of vascular endothelial growth factor-A expression, thrombospondin-2 expression, and microvessel density on the treatment effect of bevacizumab in metastatic colorectal cancer
Journal of Clinical Oncology, ISSN: 0732183X
Adrian M. Jubb; Herbert Hurwitz; Wei Bai; Holmgren; Tobin; A. Steven Guerrero; Fairooz F. Kabbinavar; Scott N. Holden; Novotny; Gretchen D. Frantz; Kenneth J. Hillan; Koeppen
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Hospital improvement in time to reperfusion in patients with acute myocardial infarction, 1999 to 2002
Journal of the American College of Cardiology, ISSN: 07351097
Robert L. McNamara; Jeph Herrin; Elizabeth H. Bradley; Edward L. Portnay; Jeptha P. Curtis; Yongfei Wang; David J. Magid; Martha Blaney; Harlan M. Krumholz
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Counterpoint: Why biogenerics are a strawman
Nature Biotechnology, ISSN: 15461696 10870156
Robert L. Garnick
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Interleukin-27R (WSX-1/T-cell cytokine receptor) gene-deficient mice display enhanced resistance to Leishmania donovani infection but develop severe liver immunopathology
American Journal of Pathology, ISSN: 00029440
Lucia E. Rosas; Anjali A. Satoskar; Kimberly M. Roth; Tracy L. Keiser; Joseph Barbi; Christopher A. Hunter; Frederic J. De Sauvage; Abhay R. Satoskar
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Discovery of thrombin activatable fibrinolysis inhibitor (TAFI)
Journal of Thrombosis and Haemostasis, ISSN: 15387836 15387933
Bertina; Van Tilburg; Haverkate; Bouma; Von Dem Borne; Meijers; William Campbell; Dan L. Eaton; Dirk F. Hendriks; Willemse
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IL-27 limits IL-2 production during Th1 differentiation
Journal of Immunology, ISSN: 00221767
Alejandro V. Villarino; Jason S. Stumhofer; Christiaan J. M. Saris; Robert A. Kastelein; Frederic J. De Sauvage; Christopher A. Hunter
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Cytokines, NF-kappaB, microenvironment, intestinal inflammation and cancer.
Cancer treatment and research, ISSN: 09273042
Arndt J Schottelius; Harald Dinter
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The crystal structure of murine coronin-1: A regulator of actin cytoskeletal dynamics in lymphocytes
Structure, ISSN: 09692126
Brent A. Appleton; Ping Wu; Wiesmann
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Proteomic studies support the use of multi-product immunoassays to monitor host cell protein impurities
Proteomics, ISSN: 16159853 16159861
Denise C. Krawitz; William F. Forrest; G. Tony Moreno; Joshua Kittleson; Kathleen M. Champion
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Detection of T lymphocytes specific for human endogenous retrovirus K (HERV-K) in patients with seminoma
AIDS Research and Human Retroviruses, ISSN: 08892229
Seth Rakoff-Nahoum; Peter Kuebler; Jonas J. Heymann; Megan E. Sheehy; Gabriel M. Ortiz; Graham S. Ogg; Jason D. Barbour; Jack Lenz; Alan D. Steinfeld; Douglas F. Nixon
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Decreased protein C, protein S, and antithrombin levels are predictive of poor outcome in Gram-negative sepsis caused by Burkholderia pseudomallei
International Journal of Infectious Diseases, ISSN: 12019712
Steven P. LaRosa; Steven M. Opal; Barbara Utterback; Sau Chi Betty Yan; Jeffrey D. Helterbrand; Andrew J.H. Simpson; Wipada Chaowagul; Nicholas J. White; Charles J. Fisher Jr.
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Pharmacokinetics/pharmacodynamics of nondepleting anti-CD4 monoclonal antibody (TRX1) in healthy human volunteers
Pharmaceutical Research, ISSN: 07248741
Chee Ng; Stefanich; Banmeet S. Anand; Fielder; Louis Vaickus
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Omalizumab pretreatment decreases acute reactions after rush immunotherapy for ragweed-induced seasonal allergic rhinitis
Journal of Allergy and Clinical Immunology, ISSN: 00916749
Thomas B. Casale; William W. Busse; Joel N. Kline; Zuhair K. Ballas; Mark H. Moss; Robert G. Townley; Masoud Mokhtarani; Vicki Seyfert-Margolis; Adam Asare; Kirk Bateman; Yamo Deniz
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Mayo Clinic consensus statement for the use of bisphosphonates in multiple myeloma
Mayo Clinic Proceedings, ISSN: 00256196
Martha Lacy; Angela Dispenzieri; Morie A. Gertz; Philip R. Greipp; Kimberly L. Gollbach; Suzanne R. Hayman; Shaji Kumar; John A. Lust; S. Vincent Rajkumar; Stephen J. Russell; Witzig; Steven R. Zeldenrust; David Dingli; P. Lief Bergsagel; Rafael Fonseca; Craig B. Reeder; A. Keith Stewart; Vivek Roy; Robert J. Dalton; Alan B. Carr; Deepak Kademani; Eugene E. Keller; Christopher F. Viozzi; Robert A. Kyle
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Erratum: Reversible self-association increases the viscosity of a concentrated monoclonal antibody in aqueous solution (Journal of Pharmaceutical Sciences [2005] 94 [1928-1940] DOI: 10.1002/jps.20347)
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Jun Liu; Mary D. H. Nguyen; Andya; Steven J. Shire
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Somatic mutations lead to an oncogenic deletion of Met in lung cancer
Cancer Research, ISSN: 00085472
Monica Kong-Beltran; Somasekar Seshagiri; Jiping Zha; Wenjing Zhu; Kaumudi Bhawe; Nerissa Mendoza; Thomas Holcomb; Kanan Pujara; Stinson; Ling Fu; Christophe Severin; Linda Rangell; Ralph H. Schwall; Lukas Amier; Dineli Wickramasinghe; Robert Yauch
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Concordance between central and local laboratory HER2 testing from a community-based clinical study
Clinical Breast Cancer, ISSN: 15268209
Josina C. Reddy; Reimann; Steven M. Anderson; Pam Klein
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Phase 1 study of erlotinib HCl alone and combined with temozolomide in patients with stable or recurrent malignant glioma
Neuro-Oncology, ISSN: 15228517
Michael D. Prados; Kathleen R. Lamborn; Susan Chang; Eric Burton; Nicholas Butowski; Mary Malec; Ami Kapadia; Jane Rabbit; Margaretta S. Page; Ann Fedoroff; Dong Xie; Kelley
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Self-association of therapeutic proteins: Implications for product development
Misbehaving Proteins: Protein (Mis)Folding, Aggregation, and Stability,
Cromwell; Chantal Felten; Heather Flores; Jun Liu; Steven J. Shire
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An overview of the pharmacokinetics and pharmacodynamics of efalizumab: A monoclonal antibody approved for use in psoriasis
Journal of Clinical Pharmacology, ISSN: 00912700 15524604
Amita Joshi; Bauer; Peter Kuebler; Mark White; Cecilia Leddy; Peter Compton; Marvin Garovoy; Paul Kwon; Patricia Walicke; Russell L Dedrick
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Effect of intravitreal injection of ranibizumab in combination with verteporfin PDT on normal primate retina and choroid
Investigative Ophthalmology and Visual Science, ISSN: 01460404
Ivana K. Kim; Deeba Husain; Norman Michaud; Edward Connolly; Anne Marie Lane; Khayyam Durrani; Ali Hafezi-Moghadam; Evangelos S. Gragoudas; Charles A. O'Neill; Joseph Beyer; Joan W. Miller
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A soluble BAFF antagonist, BR3-Fc, decreases peripheral blood B cells and lymphoid tissue marginal zone and follicular B cells in cynomolgus monkeys
American Journal of Pathology, ISSN: 00029440
Yulia Vugmeyster; Dhaya Seshasayee; Wesley S. Chang; Anahid Storn; Howell; Susan Sa; Tenea Nelson; Flavius Martin; Iqbal S. Grewal; Ellen Gilkerson; Ben Wu; Jeffrey S. Thompson; Barbara N. Ehrenfels; Song Ren; An Song; Thomas R. Gelzleichter; Dimitry Danilenko
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Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis
Cancer Cell, ISSN: 15356108
Phillips; Samir Kharbanda; Ruihuan Chen; William F. Forrest; Robert Soriano; Thomas D Wu; Anjan Misra; Janice M. Nigro; Howard Colman; Liliana Soroceanu; P. Mickey Williams; Zora Modrusan; Burt G. Feuerstein; Kenneth D. Aldape
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Asthma in older adults: Observations from the Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study
Annals of Allergy, Asthma and Immunology, ISSN: 10811206
Raymond G. Slavin; Tmirah Haselkorn; June H. Lee; Zheng; Yamo Deniz; Sally E. Wenzel
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Survivin expression in breast cancer predicts clinical outcome and is associated with HER2, VEGF, urokinase plasminogen activator and PAI-1
Annals of Oncology, ISSN: 15698041 09237534
Brid M. Ryan; Gottfried E. Konecny; Kahlert; Wang; Untch; Meng; Pegram; Podratz; John Crown; Dennis J. Slamon; Duffy
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Potential inhibitors of chemokine function: Analysis of noncovalent complexes of CC chemokine and small polyanionic molecules by ESI FT-ICR mass spectrometry
Journal of the American Society for Mass Spectrometry, ISSN: 10440305
Yonghao Yu; Matthew D. Sweeney; Ola M. Saad; Julie A. Leary
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Tolerability and Efficacy of Multiple Escalating Doses of Ranibizumab (Lucentis) for Neovascular Age-Related Macular Degeneration
Ophthalmology, ISSN: 01616420
Philip J. Rosenfeld; Jeffrey S. Heier; Gary Hantsbarger; Naveed Shams
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Ranibizumab for Treatment of Neovascular Age-Related Macular Degeneration. A Phase I/II Multicenter, Controlled, Multidose Study
Ophthalmology, ISSN: 01616420
Jeffrey S. Heier; Andrew N. Antoszyk; Peter Reed Pavan; Steven R. Leff; Philip J. Rosenfeld; Thomas A. Ciulla; Richard F. Dreyer; Ronald C. Gentile; Judy P. Sy; Gary Hantsbarger; Naveed Shams
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Apples and oranges: Comparing computer systems audits
Drug Information Journal, ISSN: 00928615
Jacques Mourrain
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The application of mechanism-based PK/PD modeling in pharmacodynamic-based dose selection of muM17, a surrogate monoclonal antibody for efalizumab
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Benjamin Wu; Amita Joshi; Song Ren; Chee Ng
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Evaluation of erlotinib in advanced non-small cell lung cancer: Impact on the budget of a U.S. health insurance plan
Journal of Managed Care Pharmacy, ISSN: 10834087
Scott D. Ramsey; Lauren Clarke; Tripthi V. Kamath; Deborah Lubeck
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Is tobacco use a problem among deaf college students?
American Annals of the Deaf, ISSN: 0002726X
Barbara A. Berman; Coen A. Bernaards; Elizabeth A. Eckhardt; Heidi B. Kleiger; Lauren Maucere; Leanne Streja; Glenn Wong; Shari Barkin; Roshan Bastani
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Design, synthesis, and biological activity of a potent Smac mimetic that sensitizes cancer cells to apoptosis by antagonizing IAPs.
ACS Chemical Biology, ISSN: 15548937
Zobel; Lan Wang; Eugene Varfolomeev; Matthew C Franklin; Linda O. Elliott; Heidi J. A. Wallweber; David C Okawa; Flygare; Domagoj Vucic; Wayne J. Fairbrother; Deshayes
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Regulation of ERK3/MAPK6 expression by BRAF
International Journal of Oncology, ISSN: 17912423 10196439
Klaus P. Hoeflich; Mike Eby; William F. Forrest; Daniel C. Gray; Janet Y. Tien; Howard M. Stern; Lesley J. Murray; David P. Davis; Zora Modrusan; Somasekar Seshagiri
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Targeted therapies in solid tumors: Monoclonal antibodies and small molecules
Human Antibodies, ISSN: 10932607
Louis M. Weiner; Hossein Borghaei
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Formulation considerations for proteins susceptible to asparagine deamidation and aspartate isomerization
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Aditya A. Wakankar; Ronald T. Borchardt
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Paracrine VEGF/VE-cadherin action on ovarian cancer permeability
Experimental Biology and Medicine, ISSN: 15353699 15353702
Limin Hu; Napoleone Ferrara; Robert B. Jaffe
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Longitudinal differences in psychological outcomes for Men with erectile dysfunction: Results from ExCEED™
Journal of Sexual Medicine, ISSN: 17436109 17436095
David M. Latini; David F. Penson; Katrine L. Wallace; Deborah Lubeck; Tom F. Lue
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Clinical and psychosocial characteristics of men with erectile dysfunction: Baseline data from ExCEED™
Journal of Sexual Medicine, ISSN: 17436109 17436095
David M. Latini; David F. Penson; Katrine L. Wallace; Deborah Lubeck; Tom F. Lue
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Synthetic therapeutic antibodies
Nature Chemical Biology, ISSN: 15524469 15524450
Sachdev S. Sidhu; Frederic A. Fellouse
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Nontraditional roles for certified pharmacy technicians in a pharmaceutical company
Journal of the American Pharmacists Association, ISSN: 15443450 15443191
Stacey M. Fung; Christine Gilmour; David McCracken; Korban Shane; Gary Matsuura
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Large-scale trends in the evolution of gene structures within 11 animal genomes
PLoS Computational Biology, ISSN: 15537358 1553734X
Mark Yandell; Chris J. Mungall; Chris Smith; Simon Prochnik; Joshua S. Kaminker; George Hartzell; Suzanna E. Lewis; Gerald M. Rubin
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TGF-β regulates the mechanical properties and composition of bone matrix
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Guive Balooch; Mehdi Balooch; Ravi K. Nalla; Stephen Schilling; Ellen H. Filvaroff; Grayson W. Marshall; Sally J. Marshall; Robert O. Ritchie; Rik Derynck; Tamara Alliston
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