Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 10701 - 10750 OF 15613 RESULTS

Unraveling TACIt functions
Nature Genetics, ISSN: 10614036
Flavius Martin; Vishva M. Dixit
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Safety and tolerability of omalizumab (Xolair®), a recombinant humanized monoclonal anti-IgE antibody
Clinical Reviews in Allergy and Immunology, ISSN: 10800549
Yamo Deniz; Niroo Gupta
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Loss of the serine/threonine kinase Fused results in postnatal growth defects and lethality due to progressive hydrocephalus
Molecular and Cellular Biology, ISSN: 02707306
Mark Merchant; Marie Evangelista; Shiuh-Ming Luoh; Gretchen D. Frantz; Sreedevi Chalasani; Richard A. D. Carano; Marjie Van Hoy; Julio Ramirez; Annie Ogasawara; Leanne McFarland; Ellen H. Filvaroff; French; Frederic J. De Sauvage
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Plasmalemmal vesicle-associated protein (PLVAP) is expressed by tumour endothelium and is upregulated by vascular endothelial growth factor-A (VEGF)
Journal of Pathology, ISSN: 00223417
Laura A. Strickland; Adrian M. Jubb; Hongo; Fiona Zhong; Jennifer Burwick; Ling Fu; Gretchen D. Frantz; Koeppen
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Distinct regulation of Ubc13 functions by the two ubiquitin-conjugating enzyme variants Mms2 and Uev1A
Journal of Cell Biology, ISSN: 00219525
Parker L. Andersen; Honglin Zhou; Landon Pastushok; Trevor Moraes; Sean McKenna; Barry Ziola; Michael J. Ellison; Vishva M. Dixit; Wei Xiao
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Bevacizumab (Avastin), a humanized anti-VEGF monoclonal antibody for cancer therapy
Biochemical and Biophysical Research Communications, ISSN: 0006291X
Napoleone Ferrara; Kenneth J. Hillan; Novotny
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Quality of care by classification of myocardial infarction. Treatment patterns for ST-segment elevation vs non-ST-segment elevation myocardial infarction
Archives of Internal Medicine, ISSN: 00039926
Matthew T. Roe; Lori Parsons; Charles V. Pollack Jr.; John G. Canto; Hal V. Barron; Nathan R. Every; William J. Rogers; Eric D. Peterson
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EphB2 is a prognostic factor in colorectal cancer
Clinical Cancer Research, ISSN: 10780432
Adrian M. Jubb; Fiona Zhong; Sheila Bheddah; Grabsch; Gretchen D. Frantz; Wolfram Mueller; Kavi; Philip Quirke; Paul G. Polakis; Koeppen
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IL-23 compensates for the absence of IL-12p70 and is essential for the IL-17 response during tuberculosis but is dispensable for protection and antigen-specific IFN-γ responses if IL-12p70 is available
Journal of Immunology, ISSN: 00221767
Shabaana A. Khader; John E. Pearl; Kaori Sakamoto; Leigh Gilmartin; Guy Bell; Dawn M. Jelley-Gibbs; Nico Ghilardi; Frederic J. De Sauvage; Andrea M. Cooper
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Common mechanisms of nerve and blood vessel wiring
Nature, ISSN: 00280836
Peter Carmeliet; Marc Tessier-Lavigne
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Perceptions of positive meaning and vulnerability following breast cancer: Predictors and outcomes among long-term breast cancer survivors
Annals of Behavioral Medicine, ISSN: 08836612
Julienne E. Bower; Beth E. Meyerowitz; Katherine A. Desmond; Coen A. Bernaards; Julia H. Rowland; Patricia A. Ganz
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Vertebrate GLD2 poly(A) polymerases in the germline and the brain
RNA, ISSN: 13558382
Labib Rouhana; Liaoteng Wang; Natascha Buter; Eun Kwak Jae; Craig A. Schiltz; Gonzalez; Ann E. Kelley; Charles F. Landry; Marvin Wickens
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Population pharmacokinetics of rituximab (anti-CD20 monoclonal antibody) in rheumatoid arthritis patients during a phase II clinical trial
Journal of Clinical Pharmacology, ISSN: 00912700
Chee Ng; Rene Bruno; Dan Combs; Brian E. Davies
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Pharmacokinetic-pharmacodynamic-efficacy analysis of efalizumab in patients with moderate to severe psoriasis
Pharmaceutical Research, ISSN: 07248741 1573904X
Chee Ng; Amita Joshi; Russell L Dedrick; Marvin Garovoy; Bauer
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Transcriptional regulatory networks activated by PI3K and ERK transduced growth signals in human glioblastoma cells
Journal of Computer Science and Technology, ISSN: 10009000
Matthias Peter; Zhi-Ping Weng; Ulla Hansen
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Vascular endothelial growth factor co-ordinates proper development of lung epithelium and vasculature
Mechanisms of Development, ISSN: 09254773
Liqing Zhao; Ke Wang; Napoleone Ferrara; Thiennu H. Vu
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Airway generation-specific differences in the spatial distribution of immune cells and cytokines in allergen-challenged rhesus monkeys
Clinical and Experimental Allergy, ISSN: 09547894
Lisa A. Miller; Stephen D. Hurst; Coffman; Tyler; Stovall; Chou; Lei F. Putney; Gershwin; Edward S. Schelegle; Plopper; Dallas M. Hyde
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Angiogenesis is required for successful bone induction during distraction osteogenesis
Journal of Bone and Mineral Research, ISSN: 08840431
Tony D. Fang; Ali Salim; Wei Xia; Randall P. Nacamuli; Samira Guccione; Hanjoon M. Song; Richard A. D. Carano; Ellen H. Filvaroff; Mark D. Bednarski; Amato J. Giaccia; Michael T. Longaker
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Role of efflux pumps and metabolising enzymes in drug delivery
Expert Opinion on Drug Delivery, ISSN: 17425247
Suresh Katragadda; Balasubrahmanyam Budda; Banmeet S. Anand; Ashim K. Mitra
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Genentech error proofs its batch records
Quality Progress, ISSN: 0033524X
Robert Bottome; Richard C. H. Chua
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Gene polymorphisms and serological markers of patients with active Crohn's disease in a clinical trial of antisense to ICAM-1
Clinical and Experimental Immunology, ISSN: 00099104
Bruce R. Yacyshyn; Schievella; Sewell; Tami
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Expression profiling the human septin gene family
Journal of Pathology, ISSN: 00223417
Peter A. Hall; Kenneth Jung; Kenneth J. Hillan; S. E. Hilary Russell
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Multimodality expression profiling shows SEPT9 to be overexpressed in a wide range of human tumours
Oncogene, ISSN: 09509232
Michael Scott; Paula L. Hyland; Gordon McGregor; Kenneth J. Hillan; S. E. Hilary Russell; Peter A. Hall
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Association of k-ras, b-raf, and p53 status with the treatment effect of bevacizumab
Journal of the National Cancer Institute, ISSN: 00278874 14602105
William L. Ince; Adrian M. Jubb; Scott N. Holden; Holmgren; Tobin; Meera Sridhar; Herbert Hurwitz; Fairooz F. Kabbinavar; Novotny; Kenneth J. Hillan; Koeppen
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Association of k-ras, b-raf, and p53 status with the treatment effect of bevacizumab
Journal of the National Cancer Institute, ISSN: 00278874 14602105
William Ince; Adrian M. Jubb; Scott N. Holden; Holmgren; Tobin; Meera Sridhar; Herbert Hurwitz; Fairooz F. Kabbinavar; Novotny; Kenneth J. Hillan; Koeppen
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A method to estimate the variance of an endpoint from an on-going blinded trial
Statistics in Medicine, ISSN: 02776715
Biao Xing; Jitendra Ganju
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Performance of a membrane adsorber for trace impurity removal in biotechnology manufacturing
Journal of Chromatography A, ISSN: 00219673
Michael Phillips; Jason Cormier; Jennifer Ferrence; Chris Dowd; Robert Kiss; Herbert Lutz; Jeffrey Carter
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Positive and negative regulation of the IL-27 receptor during lymphoid cell activation
Journal of Immunology, ISSN: 00221767
Alejandro V. Villarino; Joseph Larkin III; Christiaan J. M. Saris; Andrew J. Caton; Sophie Lucas; Wong; Frederic J. De Sauvage; Christopher A. Hunter
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Exo84 and Sec5 are competitive regulatory Sec6/8 effectors to the RalA GTPase
EMBO Journal, ISSN: 02614189
Rongsheng Jin; Jagath R. Junutula; Hugo T. Matern; Karen E. Ervin; Richard H. Scheller; Axel T. Brünger
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Identification of Pax2-regulated genes by expression profiling of the mid-hindbrain organizer region
Development (Cambridge), ISSN: 09501991
Maxime Bouchard; David Grote; Sarah E. Craven; Qiong Sun; Peter Steinlein; Meinrad Busslinger
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Serine protease cathepsin G regulates adhesion-dependent neutrophil effector functions by modulating integrin clustering
Immunity, ISSN: 10747613
Sofia Z. Raptis; Steven D. Shapiro; Pamela M. Simmons; Alec M. Cheng; Christine T.N. Pham
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Immune response in silico (IRIS): Immune-specific genes identified from a compendium of microarray expression data
Genes and Immunity, ISSN: 14664879
Abbas Alexander; Daryl T. Baldwin; Yan Ma; Wenjun Ouyang; Austin L. Gurney; Flavius Martin; Sherman Fong; Menno Van Lookeren Campagne; Godowski; P. Mickey Williams; Andrew A. Chan; Hilary F. Clark
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Tumor immunity via homeostatic T cell proliferation: Mechanistic aspects and clinical perspectives
Springer Seminars in Immunopathology, ISSN: 03444325
Roberto Baccala; Rosana Gonzalez-Quintial; Wolfgang Dummer; Argyrios N. Theofilopoulos
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Estimating heterogeneity in random effects models for longitudinal data
Biometrical Journal, ISSN: 03233847
Annabelle Lemenuel-Diot; Mallet; Laveille; Rene Bruno
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Racial differences in reperfusion therapy use in patients hospitalized with myocardial infarction: A regional phenomenon
American Heart Journal, ISSN: 00028703
Saif S. Rathore; Paul D. Frederick; Nathan R. Every; Hal V. Barron; Harlan M. Krumholz
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Epidermal growth factor receptor, protein kinase B/Akt, and glioma response to erlotinib
Journal of the National Cancer Institute, ISSN: 00278874 14602105
Daphne A. Haas-Kogan; Michael D. Prados; Tarik Tihan; Eberhard; Nannette Jelluma; Nils D. Arvold; Rachel Baumber; Kathleen R. Lamborn; Ami Kapadia; Mary Malec; Mitchel S. Berger; David Stokoe
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Immune response in silico (IRIS): Immune-specific genes identified from a compendium of microarray expression data
Genes and Immunity, ISSN: 14664879
Abbas Alexander; Daryl T. Baldwin; Yan Ma; Wenjun Ouyang; Austin L. Gurney; Flavius Martin; Fong; Menno Van Lookeren Campagne; Godowski; P. Mickey Williams; Andrew A. Chan; Hilary F. Clark
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Multiplexed serum measurement of IgG, IgA, IgM, and IgE antibody responses to therapeutic biologicals
Immunological Investigations, ISSN: 08820139
Krista McCutcheon; Edward O'Hara; David T.W. Fei
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Molecular recognition by a binary code
Journal of Molecular Biology, ISSN: 00222836
Frederic A. Fellouse; Bing Li; Deanne M. Compaan; Andrew A. Peden; Sarah G. Hymowitz; Sachdev S. Sidhu
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Evaluation of different primary recovery methods for E. coli-derived recombinant human growth hormone and compatibility with further down-stream purification
Biotechnology and Bioengineering, ISSN: 00063592
Josefine Persson; Dana C. Andersen; Philip M. Lester
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An expression-based site of origin diagnostic method designed for clinical application to cancer of unknown origin
Cancer Research, ISSN: 00085472
Richard W. Tothill; Adam Kowalczyk; Danny Rischin; Alex Bousioutas; Izhak Haviv; Ryan K. Van Laar; Waring; John Zalcberg; Robyn Ward; Andrew V. Biankin; Robert L. Sutherland; Susan M. Henshall; Kwun Fong; Jonathan R. Pollack; David D.L. Bowtell; Andrew J. Holloway
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Selective knockdown of the long variant of cellular FLICE inhibitory protein augments death receptor-mediated caspase-8 activation and apoptosis
Journal of Biological Chemistry, ISSN: 00219258
Darcie Sharp; David Lawrence; Avi Ashkenazi
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A structure-based database of antibody variable domain diversity
Journal of Molecular Biology, ISSN: 00222836
Christopher J. Bond; Wiesmann; James C. Marsters Jr.; Sachdev S. Sidhu
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Tenecteplase in the treatment of thrombosed hemodialysis grafts
CardioVascular and Interventional Radiology, ISSN: 01741551
Abigail Falk; Kathy Harbour
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Synthetic lethality of retinoblastoma mutant cells in the Drosophila eye by mutation of a novel peptidyl prolyl isomerase gene
Genetics, ISSN: 00166731
Kyle A. Edgar; Marcia Belvin; Annette L. Parks; Kellie Whittaker; Matt B. Mahoney; Monique Nicoll; Christopher C. Park; Christopher G. Winter; Feng Chen; Kim Lickteig; Ferhad Ahmad; Hanife Esengil; Matthew V. Lorenzi; Amanda Norton; Brent A. Rupnow; Laleh Shayesteh; Mariano Tabios; Lynn M. Young; Pamela M. Carroll; Casey Kopczynski; Greg D. Plowman; Lori S. Friedman; Helen L. Francis-Lang
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PAK4 mediates morphological changes through the regulation of GEF-H1
Journal of Cell Science, ISSN: 00219533
Marinella G. Callow; Sergey Zozulya; Mikhail L. Gishizky; Bahija Jallal; Tod Smeal
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Disulfide locked variants of factor VIIa with a restricted β-strand conformation have enhanced enzymatic activity
Protein Science, ISSN: 09618368
Henry R. Maun; Eigenbrot; Helga Raab; David Arnott; Lilian Phu; Sherron L. Bullens; Lazarus
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GMAP: A genomic mapping and alignment program for mRNA and EST sequences
Bioinformatics, ISSN: 13674803
Thomas D Wu; Colin K. Watanabe
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A monoclonal antibody that inhibits mouse tissue factor function [7]
Journal of Thrombosis and Haemostasis, ISSN: 15387933 15387836
Daniel Kirchhofer; Paul Moran; Sherron L. Bullens; Franklin V. Peale Jr.; Bunting
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A novel E3 ubiquitin ligase TRAC-1 positively regulates T cell activation
Journal of Immunology, ISSN: 00221767
Haoran Zhao; Connie C. Li; Jorge Pardo; Peter C. Chu; Charlene X. Liao; Jianing Huang; John G. Dong; Xiulan Zhou; Qi Huang; Betty Huang; Mark K. Bennett; Susan M. Molineaux; Henry Lu; Sarkiz Daniel-Issakani; Donald G. Payan; Esteban S. Masuda
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