Genentech: Publications

February 15, 1996

Tear Hepatocyte Growth Factor (HGF) production increases markedly after excimer laser photorefractive keratoplasty (PRK)

Investigative Ophthalmology and Visual Science, ISSN: 01460404

Qianwa Liang; Tervo; Vesaluoma; Bennett; Ralph H. Schwall; Marco Helena; Wilson

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February 15, 1996

Vascular endothelial growth factor promotes tumor dissemination by a mechanism distinct from its effect on primary tumor growth

Cancer Research, ISSN: 00085472

Ostap Melnyk; Shuman; K.Jin Kim

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February 15, 1996

Macrophage-mediated apoptosis in the developing mouse eye

Investigative Ophthalmology and Visual Science, ISSN: 01460404

Graciana Diez-Roux; Mark Labow; Horst Bluthman; Mark Moore; Richard Lang

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February 13, 1996

Isomerization of an aspartic acid residue in the complementarity-determining regions of a recombinant antibody to human IgE: Identification and effect on binding affinity

Biochemistry, ISSN: 00062960

Cacia; Rodney Keck; Presta; John Frenz

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February 10, 1996

A model for metal affinity protein precipitation

Journal of Colloid and Interface Science, ISSN: 00219797

Harish V. Iyer; Todd M. Przybycien

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February 9, 1996

Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

Cell, ISSN: 00928674

Marco A. Meraz; J. Michael White; Kathleen C. Sheehan; Bach; Scott J. Rodig; Anand S. Dighe; Daniel H. Kaplan; Riley; Andrew C. Greenlund; Dayle Campbell; Karen Carver-Moore; Raymond N. DuBois; Ross Clark; Michel Aguet; Schreiber

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February 8, 1996

High level secretion of a humanized bispecific diabody from Escherichia coli

Bio/Technology, ISSN: 0733222X

Zhu; Gerardo Zapata; Shalaby; Snedecor; Man Chert; Paul J. Carter

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February 1, 1996

Physiological regulation of early and late stages of megakaryocytopoiesis by thrombopoietin

Journal of Experimental Medicine, ISSN: 00221007

Frederic J. De Sauvage; Karen Carver-Moore; Shiuh-Ming Luoh; Anne Ryan; Mary Dowd; Dan L. Eaton; Mark Moore

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February 1, 1996

The in vivo bioactivity of vascular endothelial growth factor/vascular permeability factor is independent of N-linked glycosylation

Laboratory Investigation, ISSN: 00236837

Dirk H. Walter; Uli Hink; Takayuki Asahara; Eric Van Belle; Jeffrey Horowitz; Yukio Tsurumi; Richard L. Vandlen; Heinsohn; Keyt; Napoleone Ferrara; James F. Symes; Jeffrey M. Isner

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February 1, 1996

Electrophoretic separation of recombinant tissue-type plasminogen activator glycoforms: Validation issues for capillary isoelectric focusing methods

Electrophoresis, ISSN: 01730835

Kathy Moorhouse; Carina A. Rickel; Chen

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February 1, 1996

Cardiotrophin-1 displays early expression in the murine heart tube and promotes cardiac myocyte survival

Development (Cambridge), ISSN: 09501991

Zelin Sheng; Diane Pennica; William I. Wood; Kenneth R. Chien

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February 1, 1996

Identification of a hepatocyte growth factor autocrine loop in a murine mammary carcinoma

Cell Growth and Differentiation, ISSN: 10449523

Nader Rahimi; Eric Tremblay; Laura McAdam; Marg Park; Ralph H. Schwall; Bruce Elliott

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January 31, 1996

Multiple immune abnormalities in tumor necrosis factor and lymphotoxin-α double-deficient mice

International Immunology, ISSN: 09538178

Hans-Pietro Eugster; Matthias Müller; Urs Karrer; Bruce D. Car; Bruno Schnyder; Vicki M. Eng; Gaetane Woerly; Michel Le Hir; Franco Di Padova; Michel Aguet; Rolf M. Zinkernagel; Horst Bluethmann; Bernhard Ryffel

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January 15, 1996

Hypoxia-induced paracrine regulation of vascular endothelial growth factor receptor expression

Journal of Clinical Investigation, ISSN: 00219738

Edi Brogi; Gina Schatteman; Tiangen Wu; Elizabeth A. Kim; Lyuba Varticovski; Keyt; Jeffrey M. Isner

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January 15, 1996

Hematopoietic defects in mice lacking the sialomucin CD34

Blood, ISSN: 00064971

Jill Cheng; Baumhueter; Cacalano; Karen Carver-Moore; Harold Thibodeaux; Thomas; Hal E. Broxmeyer; Cooper; Hague; Mark Moore; Lasky

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January 15, 1996

Hematopoietic defects in mice lacking the sialomucin CD34

Blood, ISSN: 00064971

Jill Cheng; Baumhueter; Cacalano; Karen Carver-Moore; Harold Thibodeaux; Thomas; Hal E. Broxmeyer; Scott Cooper; Hague; Mark Moore; Lasky

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January 11, 1996

Vascular endothelial growth factor augments muscle blood flow and function in a rabbit model of chronic hindlimb ischemia

Journal of Cardiovascular Pharmacology, ISSN: 01602446

Walder; Carol J. Errett; Bunting; Peter Lindquist; John R. Ogez; Heinsohn; Napoleone Ferrara; G. Roger Thomas

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January 11, 1996

Pharmacokinetics and pharmacodynamics of TP-9201, a gpIIbIIIa antagonist, administered in combination with recombinant tissue-type plasminogen activator, heparin, and aspirin in beagles

Journal of Cardiovascular Pharmacology, ISSN: 01602446

Modi; Theresa Reynolds; Sharon A. Baughman; Deborah A. Thomas; Paasch; Susan Yvonne Smith

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January 9, 1996

Binding in the growth hormone receptor complex

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

James A. Wells

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January 4, 1996

Structure of the saponin adjuvant QS-21 and its base-catalyzed isomerization product by 1 H and natural abundance 13 C NMR spectroscopy

Carbohydrate Research, ISSN: 00086215

Neil E. Jacobsen; Wayne J. Fairbrother; Kensil; Lim; Deborah A. Wheeler; Powell

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January 1, 1996

Utility of the National Cooperative Growth Study database for safety reporting

Journal of Pediatrics, ISSN: 00223476

David Graves

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January 1, 1996

Translational level is a critical factor for the secretion of heterologous proteins in escherichia coli

Nature Biotechnology, ISSN: 15461696 10870156

Laura C. Simmons; Yansura

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January 1, 1996

Developmental differences in the IGF-I system response to severe and chronic calorie malnutrition

American Journal of Physiology - Endocrinology and Metabolism, ISSN: 01931849

Oster; Nancy Levin; Fielder; Icaf Robinson; Baxter; Cronin

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January 1, 1996

Binders from the Deepest Vaults

Nature Biotechnology, ISSN: 15461696 10870156

Paul J. Carter

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January 1, 1996

The obese growth hormone (GH)-deficient dwarf rat: Body fat responses to patterned delivery of GH and insulin-like growth factor-I

Endocrinology, ISSN: 00137227

Ross Clark; Deborah L. Mortensen; Carlsson; Carlsson; Carmignac; Icaf Robinson

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January 1, 1996

Transforming growth factor-β1 stimulates bone ongrowth to weight-loaded tricalcium phosphate coated implants: An experimental study in dogs

Journal of Bone and Joint Surgery - Series B, ISSN: 0301620X

Martin Lind; Søren Overgaard; Ongpipattanakul; Tue H. Nguyen; Cody Bünger; Kjeld Søballe

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January 1, 1996

An experimental model of intracranial hemorrhage during thrombolytic therapy with t-PA

Thrombosis and Haemostasis, ISSN: 03406245

Nicholas F. Paoni; Hope Steinmetz; Nancy Gillett; Refino; Julie M. Badillo; Bunting

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January 1, 1996

Gene-targeting studies of mammalian behavior: Is it the mutation or the background genotype?

Trends in Neurosciences, ISSN: 01662236

Gerlai

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January 1, 1996

Binding of cynomolgus monkey IgE to a humanized anti-human IgE antibody and human high affinity IgE receptor

Molecular Immunology, ISSN: 01615890

Meng; Naina Singh; Wai Lee T. Wong

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January 1, 1996

Differential long-term effects of insulin-like growth factor-I (IGF-I), growth hormone (GH), and IGF-I plus GH on body growth and IGF binding proteins in hypophysectomized rats

Endocrinology, ISSN: 00137227

Fielder; Deborah L. Mortensen; Phyllis Mallet; Carlsson; Baxter; Ross Clark

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January 1, 1996

A composite view of cardiac rupture in the United States National Registry of Myocardial Infarction

Journal of the American College of Cardiology, ISSN: 07351097

Richard C. Becker; Joel M. Gore; Costas Lambrew; W.Douglas Weaver; R. Michael Rubison; William J. French; Alan J. Tiefenbrunn; Laura J. Bowlby; William J. Rogers

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January 1, 1996

Structural elucidation of O-linked glycopeptides by high energy collision-induced dissociation

Journal of the American Society for Mass Spectrometry, ISSN: 10440305

Medzihradszky; Beth Gillece-Castro; Townsend; Alma Burlingame; Hardy

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January 1, 1996

Hepatocyte proliferation and serum hepatocyte growth factor levels in patients with alcoholic hepatitis

Journal of Hepatology, ISSN: 01688278

Kenneth J. Hillan; Martin C. Logan; Rod K. Ferrier; George L. Bird; Bennett; Ian C. McKay; Roderick N. M. MacSween

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January 1, 1996

Hematologically important mutations: X-Linked chronic granulomatous disease

Blood Cells, Molecules, and Diseases, ISSN: 10799796

Andrew R. Cross; John T. Curnutte; Julie Rae; Heyworth

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January 1, 1996

Regulation of transplacental virus infection by developmental and immunological factors: Studies with lactate dehydrogenase-elevating virus

Virus Research, ISSN: 01681702

Thomas R. Haven; Raymond R.R. Rowland; Peter G. W. Plagemann; Grace H.W. Wong; Sarahann E. Bradley; William A. Cafruny

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January 1, 1996

186Re-labeled antibodies to p185HER2 as HER2-targeted radioimmunopharmaceutical agents: Comparison of physical and biological characteristics with 125I and 131I-labeled counterparts

Cancer Biotherapy and Radiopharmaceuticals, ISSN: 10849785

Claire Kotts; Su; Cecilia Leddy; Dodd; Scates; Shalaby; Wirth; Giltinan; Schroff; Fritzberg; Shepard; Dennis J. Slamon; Hutchins

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January 1, 1996

Vascular endothelial growth factor, a specific regulator of angiogenesis

Current Opinion in Nephrology and Hypertension, ISSN: 10624821

Napoleone Ferrara; Bunting

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January 1, 1996

Follistatins and α2-macroglobulin are soluble binding proteins for inhibinand activin

Hormone Research, ISSN: 16632826 16632818

Mather

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January 1, 1996

GDNF induces a dystonia-like state in neonatal rats and stimulates dopamine and serotonin synthesis

Neuron, ISSN: 08966273

Klaus D. Beck; Ian Irwin; Janet Valverde; Thomas J. Brennan; J. William Langston; Franz Hefti

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January 1, 1996

Regulated release and polarized localization of brain-derived neurotrophic factor in hippocampal neurons

Molecular and Cellular Neuroscience, ISSN: 10447431

Goodman; Janet Valverde; Filip Lim; Michael D. Geschwind; Howard J. Federoff; Alfred I. Geller; Franz Hefti

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January 1, 1996

Locating the unpaired cysteine of tissue-type plasminogen activator

Protein Engineering, ISSN: 02692139

Louis C. Sehl; Hung V. Nguyen; Lea Berleau; Patricia Arcila; William F. Bennett; Keyt

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January 1, 1996

Human cardiotrophin-1: Protein and gene structure, biological and binding activities, and chromosomal localization

Cytokine, ISSN: 10434666

Diane Pennica; Todd A. Swanson; Kenneth J. Shaw; Wun-Jing Kuang; Christa Gray; Barbara G. Beatty; William I. Wood

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January 1, 1996

Liquid-liquid emulsification by rotor/stator homogenization

Journal of Controlled Release, ISSN: 01683659

Maa; Chung C. Hsu

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January 1, 1996

Multicopy suppressors of prc mutant Escherichia coli include two HtrA (DegP) protease homologs (HhoAB), DksA, and a truncated rlpA

Journal of Bacteriology, ISSN: 00219193

Bass; Qimin Gu; Anthony Christen

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January 1, 1996

Flux measurements across Caco-2 monolayers may predict transport in human large intestinal tissue

Journal of Pharmaceutical Sciences, ISSN: 00223549

Rubas; Cromwell; Shahrokh; Villagran; Nguyen; Wellton; Tue H. Nguyen; Mrsny

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January 1, 1996

Penicillamine: An extractable chiral auxiliary providing excellent stereocontrol

Tetrahedron Asymmetry, ISSN: 09574166

Lutz S. Richter; Thomas Gadek

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January 1, 1996

Protection of MN-rgp120-immunized chimpanzees from heterologous infection with a primary isolate of human immunodeficiency virus type 1

Journal of Infectious Diseases, ISSN: 00221899

Berman; Murthy; Wrin; Vennari; Kathy Cobb; Eastman; Mark Champe; Nakamura; Donna Davison; Powell; Bussiere; Francis; Matthews; Timothy Gregory; John F. Obijeski

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January 1, 1996

Gene targeting in neuroscience: The systemic approach

Trends in Neurosciences, ISSN: 01662236

Gerlai

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January 1, 1996

Design and application of a low-temperature Peltier-cooling microscope stage

Journal of Pharmaceutical Sciences, ISSN: 00223549

Chung C. Hsu; Andrew J. Walsh; Hoc M. Nguyen; David E. Overcashier; Hans Koning-Bastiaan; Ralph C. Bailey; Steven L. Nail

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January 1, 1996