Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 13751 - 13800 OF 15703 RESULTS

May 1, 1994

Failure to demonstrate long-lived MHC saturation both in vitro and in vivo: Implications for therapeutic potential of MHC-blocking peptides

Journal of Immunology, ISSN: 00221767

Glenn Y. Ishioka; Luciano Adorini; Jean-Charles Guery; Federico C. A. Gaeta; Renee LaFond; Jeff Alexander; Powell; Alessandro Sette; Howard M. Grey

May 1, 1994

The stoichiometry of growth hormone-binding protein complexes in human plasma: Comparison with cell surface receptors

Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X

Gerhard Baumann; Henry B. Lowman; Moises Mercado; James A. Wells

May 1, 1994

Production of the RANTES chemokine in delayed-type hypersensitivity reactions: Involvement of macrophages and endothelial cells

Journal of Experimental Medicine, ISSN: 00221007

Odile Devergne; Anne Marfaing-Koka; Thomas J. Schall; Marie-Bénédicte Leger-Ravet; Michael D Sadick; Michel Peuchmaur; Marie-Claude Crevon; Tim Kim; Pierre Galanaud; Dominique Emilie

April 28, 1994

Electronic resources in human-computer interaction

Conference on Human Factors in Computing Systems - Proceedings,

Gary Perlman; Jakob Nielsen; John Morris; Brian Shackel

April 15, 1994

Peptidomimetic inhibitors of Ras farnesylation

Chemistry and Biology, ISSN: 10745521

James C. Marsters Jr.; Robert S. McDowelll; Mark E. Reynolds; Todd C. Somers; Joseph L. Goldstein; Michael S. Brown; Guy L. James

April 15, 1994

Vascular endothelial growth factor: A cytokine modulating endothelial function in rheumatoid arthritis

Journal of Immunology, ISSN: 00221767

Alisa Koch; Lisa A. Harlow; G. Kenneth Haines; Edward P. Amento; Elaine N. Unemori; Wei Lee Wong; Richard M. Pope; Napoleone Ferrara

April 15, 1994

Vascular endothelial growth factor: A cytokine modulating endothelial function in rheumatoid arthritis

Journal of Immunology, ISSN: 00221767

Alisa Koch; Lisa A. Harlow; G. Kenneth Haines; Edward P. Amento; Elaine N. Unemori; Wai Lee T. Wong; Richard M. Pope; Napoleone Ferrara

April 12, 1994

Neurotrophin 3 stimulates the differentiation of motoneurons from avian neural tube progenitor cells

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Lea Averbuch-Heller; Merav Pruginin; Nitza Kahane; Tsoulfas; Parada; Rosenthal; Chaya Kalcheim

April 12, 1994

Neurotrophin 4/5 is a trophic factor for mammalian facial motor neurons

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Vassilis E. Koliatsos; Michelle H. Cayouette; Lucy R. Berkemeier; Richard E. Clatterbuck; Donald L. Price; Rosenthal

April 8, 1994

Retention and degradation of proteins containing an uncleaved glycosylphosphatidylinositol signal

Journal of Biological Chemistry, ISSN: 00219258

Mark C. Field; Paul Moran; Wenlu Li; Gilbert-Andre Keller; Caras

April 4, 1994

Mono-N-alkylation of anthranilamides via quinazolinones. An efficient synthesis of G5598, a benzodiazepine dione gpIIbIIIa antagonist

Tetrahedron Letters, ISSN: 00404039

Robert R. Webb II; Peter L. Barker; Mark Baier; Mark E. Reynolds; Kirk D. Robarge; Brent Blackburn; Maureen Tischler; Kenneth J Weese

April 1, 1994

Ecotin Is a Potent Anticoagulant and Reversible Tight-Binding Inhibitor of Factor Xa

Biochemistry, ISSN: 15204995 00062960

Jana L. Seymour; Robert N. Lindquist; Dennis; Lazarus; Moffat; Yansura; Dorothea Reilly; Wessinger

April 1, 1994

Protein Folding Activities of Escherichia coli Protein Disulfide Isomerase

Biochemistry, ISSN: 15204995 00062960

John C. Joly; James R. Swartz

April 1, 1994

A faster-acting and more potent form of tissue plasminogen activator

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Keyt; Nicholas F. Paoni; Refino; Lea Berleau; Hung V. Nguyen; Alice M. Chow; Lai; Luis Peña; Cheryl Pater; John R. Ogez; Etcheverry; David Botstein; William F. Bennett

April 1, 1994

Signal transduction versus buffering activity in Ca2+-binding proteins

Nature Structural Biology, ISSN: 10728368

Nicholas J. Skelton; Johan Kördel; Mikael Akke; Sture Forsén; Walter J. Chazin

April 1, 1994

Regulation of neurotrophin receptors during the maturation of the mammalian visual system

Journal of Neuroscience, ISSN: 02706474

Karen L. Allendoerfer; Robert J. Cabelli; Escandon; David R. Kaplan; Nikolics; Carla J. Shatz

March 25, 1994

Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neurons

Cell, ISSN: 00928674

Crowley; Spencer; Merry Nishimura; Grace Chan; Sharon Pitts-Meek; Mark P. Armaninl; Lanway H. Ling; McMahon; David L. Shelton; Levinson; Phillips

March 18, 1994

Expression of the duffy antigen in K562 cells: Evidence that it is the human erythrocyte chemokine receptor

Journal of Biological Chemistry, ISSN: 00219258

Asok Chaudhuri; Valerie Zbrzezna; Julia Polyakova; A. Oscar Pogo; Joseph Hesselgesser; Richard Horuk

March 15, 1994

Neutralization of IL-8 inhibits neutrophil influx in a rabbit model of endotoxin-induced pleurisy

Journal of Immunology, ISSN: 00221767

V. Courtney Broaddus; Alice M. Boylan; John M. Hoeffel; K.Jin Kim; Michael D Sadick; Anan Chuntharapai; Hébert

March 14, 1994

Two new procedures for the introduction of benzyl-type protecting groups for thiols

Tetrahedron Letters, ISSN: 00404039

Lutz S. Richter; James C. Marsters Jr.; Thomas Gadek

March 4, 1994

Vascular endothelial growth factor is induced in response to transforming growth factor-β in fibroblastic and epithelial cells

Journal of Biological Chemistry, ISSN: 00219258

Liisa Pertovaara; Arja Kaipainen; Tuija Mustonen; Arto Orpana; Napoleone Ferrara; Olli Saksela; Kari Alitalo

March 1, 1994

Modification of CD4 Immunoadhesin with Monomethoxy poly (ethylene glycol) Aldehyde via Reductive Alkylation

Bioconjugate Chemistry, ISSN: 15204812 10431802

Steven M. Chamow; Peers; Timothy P. Kogan; Michael C. Venuti; Thomas Gadek; Reed J. Harris; Joyce Mordenti; Steven Shak; Avi Ashkenazi

March 1, 1994

Characterization of Humanized Anti-TAC, an Antibody Directed Against the Interleukin 2 Receptor, Using Electrospray Ionization Mass Spectrometry by Direct Infusion, LC/MS, and MS/MS

Analytical Chemistry, ISSN: 15206882 00032700

Derf A. Lewis; Andrew W. Guzzetta; William S. Hancock; Maureen Costello

March 1, 1994

Functional analysis of the cysteine residues of activin A

Molecular Endocrinology, ISSN: 08888809

Anthony J. Mason

February 25, 1994

Genetically engineered proinsulin constitutively processed and secreted as mature, active insulin

Journal of Biological Chemistry, ISSN: 00219258

Debyra J. Groskreutz; Mark X. Sliwkowski; Cornelia M. Gorman

February 15, 1994

Neutralizing monoclonal antibodies to human IL-8 receptor A map to the NH2-terminal region of the receptor

Journal of Immunology, ISSN: 00221767

Anan Chuntharapai; James Lee; Burnier; William I. Wood; Hébert; Jin Kim

February 15, 1994

Fas antigen and p55 TNF receptor signal apoptosis through distinct pathways

Journal of Immunology, ISSN: 00221767

Grace H.W. Wong; David V. Goeddel

February 1, 1994

Cis,cis-Muconate Lactonizing Enzyme from Trichosporon cutaneum: Evidence for a Novel Class of Cycloisomerases in Eucaryotes

Biochemistry, ISSN: 15204995 00062960

Paul Mazur; Wolfgang A. Pieken; Scott R. Budihas; Suzanne E. Williams; Susan Wong; John W. Kozarich

February 1, 1994

Protein Sorting by High Performance Liquid Chromatography. 2. Separation of Isophosphorylates of Recombinant Human DNase I on a Polyethylenimine Column

Analytical Chemistry, ISSN: 15206882 00032700

John Frenz; Quan; Cacia; Democko; Robert L. Bridenbaugh; McNerney

February 1, 1994

Cis,cis-Muconate Lactonizing Enzyme from Trichosporon cutaneum: Evidence for a Novel Class of Cycloisomerases in Eucaryotes

Biochemistry, ISSN: 15204995 00062960

Paul Mazur; Wolfgang A. Pieken; Scott R. Budihas; Suzanne E. Williams; Susan C. Wong; John W. Kozarich

January 28, 1994

Cloning of FRK, a novel human intracellular SRC-like tyrosine kinaseencoding gene

Gene, ISSN: 03781119

James Lee; Zhengyu Wang; Shiuh-Ming Luoh; William I. Wood; David T. Scadden

January 14, 1994

Identification and characterization of a novel tyrosine kinase from megakaryocytes

Journal of Biological Chemistry, ISSN: 00219258

Brian D. Bennett; Sally Cowley; Shuxian Jiang; Roanna London; Bijia Deng; Jadwiga Grabarek; Jerome E. Groopman; David V. Goeddel; Hava Avraham

January 4, 1994

Structure from function: Screening structural models with functional data

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Jin; Fred E. Cohen; James A. Wells

January 1, 1994

The X-ray structure of a growth hormone-prolactin receptor complex

Nature, ISSN: 00280836

Somers; Ultsch; De Vos; Anthony A. Kossiakoff

January 1, 1994

In vitro megakaryocytopoietic and thrombopoietic activity of c-mpl ligand (TPO) on purified murine hematopoietic stem cells

Blood, ISSN: 00064971

Francis C. Zeigler; Frederic J. De Sauvage; Widmer; Gilbert-Andre Keller; Christopher J. Donahue; Schreiber; Malloy; Hass; Dan L. Eaton; William Matthews

January 1, 1994

Rac translocates independently of the neutrophil NADPH oxidase components p47(phox) and p67(phox). Evidence for its interaction with flavocytochrome b558

Journal of Biological Chemistry, ISSN: 00219258

Heyworth; Benjamin P. Bohl; Bokoch; John T. Curnutte

January 1, 1994

Sialomucin ligands for selectins: a new family of cell adhesion molecules.

Princess Takamatsu symposia,

Lasky

January 1, 1994

Evaporation of Aqueous Aerosols Produced by Jet Nebulizers: Effects on Particle Size and Concentration of Solution in the Droplets

Journal of Aerosol Medicine: Deposition, Clearance, and Effects in the Lung, ISSN: 15579026 08942684

Phipps; Gonda

January 1, 1994

Humanized Monoclonal Antibodies

Annual Reports in Medicinal Chemistry, ISSN: 00657743

Presta

January 1, 1994

Chinese hamster ovary cells contain transcriptionally active full-length type C proviruses

Journal of Virology, ISSN: 0022538X

Yolanda S. Lie; Elicia M. Penuel; Mari-Anne L. Low; Nguyen; Jocelyn O. Mangahas; Anderson; Christos J. Petropoulos

January 1, 1994

Approaches to analysis of aggregates and demonstrating mass balance in pharmaceutical protein (basic fibroblast growth factor) formulations

Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549

Shahrokh; Stratton; Eberlein; Y. John Wang

January 1, 1994

Report on the Genetic Stability Symposium. April 10-12, 1991. West Coast Chapter, Parenteral Drug Association.

Developments in biological standardization, ISSN: 03015149

Robert L. Garnick; Helder

January 1, 1994

New techniques in protein chemistry.

Developments in biological standardization, ISSN: 03015149

O'Connor; Rodney Keck; Reed J. Harris; Field

January 1, 1994

Mammalian nonsense codons can be cis effectors of nuclear mRNA half-life

Molecular and Cellular Biology, ISSN: 02707306

Phillip Belgrader; Jiu Cheng; Xianbo Zhou; Lori S. Stephenson; Lynne E. Maquat

January 1, 1994

Interferon-α and induction of type I diabetes

Biomedicine and Pharmacotherapy, ISSN: 07533322

Tracy Stewart

January 1, 1994

Islet expression of interferon-α precedes diabetes in both the BB rat and streptozotocin-treated mice

Immunity, ISSN: 10747613

Huang; Hultgren; Noel Dybdal; Stewart

January 1, 1994

Use of polymerase chain reaction (PCR) in the development of a recombinant organism.

Developments in biological standardization, ISSN: 03015149

Helder; Utter

January 1, 1994

Activation of TNF‐R1 receptor in the presence of copper kills TNF resistant CEM leukemic T cells

Journal of Cellular Physiology, ISSN: 10974652 00219541

H. Garrett Wada; Katherine S. Fok; Brian M. Fendly; Nancy Y. Chiang; Howard H. Sussman

January 1, 1994

Dissecting the energetics of an antibody‐antigen interface by alanine shaving and molecular grafting

Protein Science, ISSN: 1469896X 09618368

Jin; James A. Wells

January 1, 1994

Consistency and stability of recombinant fermentations.

Developments in biological standardization, ISSN: 03015149

Wiebe; Stuart E. Builder

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