Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 14151 - 14200 OF 15614 RESULTS

Nerve growth factor increases calcium binding protein (Calbindin-D28K) in rat olfactory bulb
Brain Research, ISSN: 00068993
Iacopino; Christakos; Modi; C.Anthony Altar
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Recombinant Human DNase Inhalation in Normal Subjects and Patients With Cystic Fibrosis: A Phase 1 Study
JAMA - Journal of the American Medical Association, ISSN: 15383598 00987484
Moira L. Aitken; Wylie Burke; Gwen McDonald; Shak; A. Bruce Montgomery; Arnold L. Smith
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Differentiation factor/leukemia inhibitory factor protection against lethal endotoxemia in mice: Synergistic effect with interleukin 1 and tumor necrosis factor
Journal of Experimental Medicine, ISSN: 15409538 00221007
Richard Alexander; Grace H.W. Wong; Gerard M. Doherty; David J. Venzon; Douglas L. Fraker; Jeffrey A. Norton
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A preliminary study of aerosolized recombinant human deoxyribonuclease i in the treatment of cystic fibrosis
New England Journal of Medicine, ISSN: 15334406 00284793
Richard C. Hubbard; McElvaney; Birrer; Woodrow W. Robinson; Clara Jolley; Ronald G. Crystal; Shak; Margaret Wu; Milica S. Chernick
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Computer simulation as a tool for the rapid optimization of the high-performance liquid chromatogrpahic separation of a tryptic digest human growth hormone
Journal of Chromatography A, ISSN: 00219673
Chloupek; William S. Hancock; Lloyd R. Snyder
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Analysis of solvent structure in proteins using neutron D2OH2O solvent maps: Pattern of primary and secondary hydration of trypsin
Proteins: Structure, Function and Bioinformatics, ISSN: 10970134 08873585
Anthony A. Kossiakoff; Sintchak; Shpungin; Presta
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Identity of a differentiation inhibiting factor for mouse myeloid leukemia cells with NM23/nucleoside diphosphate kinase
Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X
Junko Okabe-Kado; Takashi Kasukabe; Yoshio Honma; Moriaki Hayashi; William J. Henzel; Hozumi
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The structure of human lymphotoxin (tumor necrosis factor-β) at 1.9-Å resolution
Journal of Biological Chemistry, ISSN: 00219258
Michael J. Eckt; Ultsch; Rinderknecht; De Vos; Stephen R. Sprang
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Incorporation of a Stabilizing Ca2+-Binding Loop into Subtilisin BPN
Biochemistry, ISSN: 15204995 00062960
Braxton; James A. Wells
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Mambin, a Potent Glycoprotein Ilb-IIIa Antagonist and Platelet Aggregation Inhibitor Structurally Related to the Short Neurotoxins
Biochemistry, ISSN: 15204995 00062960
Robert S. McDowell; Dennis; Michael G. Mulkerrin; Lazarus; Louie; Shuster
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Antigen Binding Thermodynamics and Antiproliferative Effects of Chimeric and Humanized anti-p185HER2 Antibody Fab Fragments
Biochemistry, ISSN: 15204995 00062960
Robert F. Kelley; Mark P. O'Connell; Paul J. Carter; Presta; Eigenbrot; Michael Covarrubias; Snedecor; James H. Bourell; David Vetterlein
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The Ca2+Ion and Membrane Binding Structure of the Gla Domain of Ca-Prothrombin Fragment 1
Biochemistry, ISSN: 15204995 00062960
Soriano-Garcia; Kaillathe Padmanabhan; Alexander Tulinsky; De Vos
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13C NMR Investigation of the Anomeric Specificity of CMP-TV-Acetylneuraminic Acid Synthetase from Escherichia coli
Biochemistry, ISSN: 15204995 00062960
Michael G. Ambrose; Freese; Mary S. Reinhold; Williie F. Vann; Warner
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Human Natriuretic Peptide Receptor-A Guanylyl Cyclase Is Self-Associated prior to Hormone Binding
Biochemistry, ISSN: 15204995 00062960
David G Lowe
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The Type II Isoform of Bovine Brain Protein L-Isoaspartyl Methyltransferase Has an Endoplasmic Reticulum Retention Signal (…RDEL) at Its C-Terminus
Biochemistry, ISSN: 15204995 00062960
Steven M. Potter; Brett A. Johnson; Agnes Henschen; Aswad; Andrew W. Guzzetta
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Characterization of a Recombinant Extracellular Domain of the Type 1 Tumor Necrosis Factor Receptor: Evidence for Tumor Necrosis Factor-α Induced Receptor Aggregation
Biochemistry, ISSN: 15204995 00062960
Diane Pennica; Paul E. Borchardt; Lewis; David V. Goeddel; William J. Kohr; Helga Raab; Brian M. Fendly; Steven J. Shire
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Engagement of major histocompatibility complex class II molecules by superantigen induces inflammatory cytokine gene expression in human rheumatoid fibroblast-like synoviocytes
Journal of Experimental Medicine, ISSN: 15409538 00221007
Walid Mourad; Khalil Mehindate; Thomas J. Schall; Shaun R. McColl
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A Region of Tissue Plasminogen Activator That Affects Plasminogen Activation Differentially with Various Fibrin(ogen)-Related Stimulators
Biochemistry, ISSN: 15204995 00062960
Eastman; Florian M. Wurm; Robert Van Reis; Deborah L. Higgins
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A role for IGF-1 in the rescue of CNS neurons following hypoxic-ischemic injury
Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X
Peter Gluckman; Nicolin Klempt; Jian Guan; Carina Mallard; Ernest Sirimanne; Mike Dragunow; Martin Klempt; Singh; Chris Williams; Nikolics
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Pharmacokinetic modeling for evaluating dosing strategies of anti-p185HER2 monoclonal antibodies
Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings, ISSN: 1557170X
Schoenhoff; Daniel A. Maneval; Hutchins; Gregory S. Blank; David Vetterlein; Joyce Mordenti; Green
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Immunodominant structures of human growth hormone identified by homolog-scanning mutagenesis
Molecular Immunology, ISSN: 01615890
Joseph R. Weber; Nelson; Cunningham; James A. Wells; Fong
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Human seminal relaxin is a product of the same gene as human luteal relaxin
Endocrinology, ISSN: 19457170 00137227
Winslow; Shih; James H. Bourell; Gerson Weiss; Baron R. Reed; Stults; Laura T. Goldsmith
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Thyroid follicular cells produce interleukin-8
Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X
Weetman; Bennett; Wai Lee T. Wong
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Passive immunoneutralization with a monoclonal antibody reveals a role for endogenous activin-b in mediating fsh hypersecretion during estrus and following ovariectomy of hypophysectomized, pituitary-grafted rats
Endocrinology, ISSN: 19457170 00137227
Louis V. DePaolo; Bald; Brian M. Fendly
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Vascular endothelial growth factor messenger ribonucleic acid expression in the primate ovary
Endocrinology, ISSN: 19457170 00137227
Ravindranath; Lynda Little-Ihrig; Phillips; Napoleone Ferrara; Anthony J. Zeleznik
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Recovery of Cholinergic Phenotype in the Injured Rat Neostriatum: Roles for Endogenous and Exogenous Nerve Growth Factor
Journal of Neurochemistry, ISSN: 14714159 00223042
C.Anthony Altar; Armanini; Dugich-Djordjevic; Bennett; Regina Williams; Shamiram Feinglass; Vincent R. Anicetti; Sinicropi; Bakhit
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Activity and Biospecificity of Proteolyzed Forms and Dimeric Combinations of Recombinant Human and Murine Nerve Growth Factor
Journal of Neurochemistry, ISSN: 14714159 00223042
Louis E. Burton; Charles H. Schmelzer; Szonyi; Yedinak; Gorrell
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High resolution removal of virus from protein solutions using a membrane of unique structure
Bio/Technology, ISSN: 0733222X
Anthony J. DiLeo; Anthony E. Allegrezza Jr.; Stuart E. Builder
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DnaK-Mediated alterations in human growth hormone protein inclusion bodies
Bio/Technology, ISSN: 0733222X
Paul Blum; Mark Velligan; Lin; Abdul Matin
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Polyethylene glycol enhanced protein refolding
Bio/Technology, ISSN: 0733222X
Cleland; Stuart E. Builder; James R. Swartz; Maijorie Winkler; Judy H. Chang; Daniel I. C. Wang
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The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor
Science, ISSN: 00368075
Carlie De Vries; Escobedo; Hikaru Ueno; Houck; Napoleone Ferrara; Williams
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Posttranslational modifications in the amino-terminal region of the large subunit of ribulose-1,5-bisphosphate carboxylase/oxygenase from several plant species
Plant Physiology, ISSN: 00320889
Robert L. Houtz; Loelle Poneleit; Samantha B. Jones; Malcolm Royer; Stults
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Vascular endothelial growth factor induces interstitial collagenase expression in human endothelial cells
Journal of Cellular Physiology, ISSN: 10974652 00219541
Elaine N. Unemori; Napoleone Ferrara; Eugene A. Bauer; Edward P. Amento
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Biochemical properties of the 75-kDa tumor necrosis factor receptor. Characterization of ligand binding, internalization, and receptor phosphorylation
Journal of Biological Chemistry, ISSN: 00219258
Diane Pennica; Lam; Mize; Weber; Lewis; Brian M. Fendly; Michael T. Lipari; David V. Goeddel
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Chemical heterogeneity as a result of hydroxylamine cleavage of a fusion protein of human insulin-like growth factor I
Biochemical Journal, ISSN: 02646021
Eleanor Canova-Davis; Eng; Mukku; David H. Reifsnyder; Charles V. Olson; Victor Ling
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Relaxin binding in the rat heart atrium
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Phyllis L. Osheroff; Cronin; Julie A. Lofgren
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Virions of primary human immunodeficiency virus type 1 isolates resistant to soluble CD4 (sCD4) neutralization differ in sCD4 binding and glycoprotein gp120 retention from sCD4-sensitive isolates
Journal of Virology, ISSN: 0022538X
John P. Moore; Jane A. Mckeating; Yaoxing Huang; Avi Ashkenazi; David D. Ho
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Utilization of homologous proteins to evaluate the safety of recombinant human proteins - case study: recombinant human interferon-gamma (rhIFN-γ)
Toxicology Letters, ISSN: 03784274
Green; Timothy G. Terrell
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The apolipoprotein(a) moiety of lipoprotein(a) interacts with the complement activation fragment iC3b but does not functionally affect C3 activation or degradation
Atherosclerosis, ISSN: 00219150
Paul S. Seifert; Iris Roth; Zioncheck
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Human natriuretic peptide receptor-A guanylyl cyclase. Hormone cross- linking and antibody reactivity distinguish receptor glycoforms
Journal of Biological Chemistry, ISSN: 00219258
David G Lowe; Brian M. Fendly
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Pituitary follicular cells secrete an inhibitor of aortic endothelial cell growth: Identification as leukemia inhibitory factor
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Napoleone Ferrara; Jane Winer; William J. Henzel
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Use of rapid serial sampling of creatine kinase MB for very early detection of myocardial infarction in patients with acute chest pain
American Heart Journal, ISSN: 10976744 00028703
Michael M. Marin; Sam L. Teichman
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Immunodominant structures of human growth hormone identified by homolog-scanning mutagenesis
Molecular Immunology, ISSN: 01615890
Joseph R. Weber; Nelson; Cunningham; James A. Wells; Sherman Fong
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Phase I study of continuous-infusion soluble CD4 as a single agent and in combination with oral dideoxyinosine therapy in children with symptomatic human immunodeficiency virus infection
Journal of Pediatrics, ISSN: 00223476
Robert N. Husson; Yoomie Chung; Joyce Mordenti; Karina M. Butler; Chen; A-M. Duliege; Pim Brouwers; Paul Jarosinski; Brigitta U. Mueller; Arthur J. Ammann; Philip A. Pizzo
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Truncated and native insulinlike growth factor I enhance mucosal adaptation after jejunoileal resection
Gastroenterology, ISSN: 00165085
Jon A. Vanderhoof; Robert H. McCusker; Ross Clark; Hamid Mohammadpour; Darcy J. Blackwood; Richard F. Harty; Jung H.Y. Park
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O-linked fucose is present in the first epidermal growth factor domain of factor XII but not protein C
Journal of Biological Chemistry, ISSN: 00219258
Reed J. Harris; Victor Ling; Spellman
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The gene encoding human plasma carboxypeptidase B (CPB2) resides on chromosome 13
Genomics, ISSN: 10898646 08887543
Siao Ping Tsai; Drayna
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The cytoplasmic domain of tissue factor is phosphorylated by a protein kinase C-dependent mechanism
Journal of Biological Chemistry, ISSN: 00219258
Zioncheck; Roy; Gordon A. Vehar
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Paracrine Regulation of Reproductive Function by Inhibin and Activin
Proceedings of the Society for Experimental Biology and Medicine, ISSN: 15353699 00379727
Mather; Woodruff; Lynne Krummen
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Molecular structural basis of ligand selectivity for 5-HT2 versus 5-HT1C cortical receptors
Naunyn-Schmiedeberg's Archives of Pharmacology, ISSN: 14321912 00281298
Pierce; Joanne Y. Kim; Peroutka
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