Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 14151 - 14200 OF 15703 RESULTS

Purification, receptor binding analysis, and biological characterization of human melanoma growth stimulating activity (MGSA). Evidence for a novel MGSA receptor
Journal of Biological Chemistry, ISSN: 00219258
Richard Horuk; Yansura; Dorothea Reilly; Steven A. Spencer; James H. Bourell; William J. Henzel; Glenn C. Rice; Elaine N. Unemori
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Inactivation of the IGF‐I Gene in Mice Results in Perinatal Lethality
Annals of the New York Academy of Sciences, ISSN: 17496632 00778923
Powell-Braxton; Hollingshead; Giltinan; Sharon Pitts-Meek; Stewart
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Genetic aspects of cancer
Advances in Human Genetics, ISSN: 0065275X
Goddard; Solomon
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Models of human endocrine disorders in transgenic rodents
Trends in Endocrinology and Metabolism, ISSN: 10432760
Stewart
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Bovine L-selectin: A peripheral lymphocyte homing receptor
Veterinary Immunology and Immunopathology, ISSN: 01652427
Bosworth; Dowbenko; Shuster; Harp
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Structural and functional aspects of RGD-containing protein antagonists of glycoprotein IIb-IIIa
Current Opinion in Biotechnology, ISSN: 09581669
Lazarus; Robert S. McDowell
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Engineering Fab' fragments for efficient F(ab)2 formation in Escherichia coli and for improved in vivo stability
Journal of Immunology, ISSN: 00221767
Maria L. Rodrigues; Snedecor; Christina Y. Chen; Wai Lee T. Wong; Shaily Garg; Gregory S. Blank; Daniel A. Maneval; Paul J. Carter
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Cloning and expression of a human CDC42 GTPase-activating protein reveals a functional SH3-binding domain
Journal of Biological Chemistry, ISSN: 00219258
Elisabeth T. Barfod; Yi Zheng; Wun-Jing Kuang; Matthew J. Hart; Tony Evans; Richard A. Cerione; Avi Ashkenazi
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Intravenous interleukin-8 inhibits granulocyte emigration from rabbit mesenteric venules without altering L-selectin expression or leukocyte rolling
Journal of Immunology, ISSN: 00221767
Klaus Ley; Baker; Myron I. Cybulsky; Gimbrone Jr.; Francis W. Luscinskas
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Epidermal growth factor stimulates vascular endothelial growth factor production by human malignant glioma cells: A model of glioblastoma multiforme pathophysiology
Molecular Biology of the Cell, ISSN: 10591524
Corey K. Goldman; Jin Kim; Wai Lee T. Wong; Vickie King; Tommy Brock; G. Yancey Gillespie
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The molecular basis for growth hormone-receptor interactions
Recent Progress in Hormone Research, ISSN: 00799963
James A. Wells; Cunningham; Fuh; Henry B. Lowman; Bass; Michael G. Mulkerrin; Ultsch; Abraham M. Devos
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5‐Hydroxytryptamine Receptors
Journal of Neurochemistry, ISSN: 14714159 00223042
Peroutka
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Difficulties in Precise Quantitation of CD4+T Lymphocytes for Clinical Trials: A Review
Biologicals, ISSN: 10958320 10451056
David T.W. Fei; Paxton; Chen
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Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
Nature, ISSN: 00280836
K.Jin Kim; Bing Li; Jane Winer; Armanini; Nancy Gillett; Phillips; Napoleone Ferrara
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Vascular endothelial growth factor
Trends in Cardiovascular Medicine, ISSN: 10501738
Napoleone Ferrara
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The Human Erythrocyte Inflammatory Peptide (Chemokine) Receptor. Biochemical Characterization, Solubilization, and Development of a Binding Assay for the Soluble Receptor
Biochemistry, ISSN: 15204995 00062960
Richard Horuk; Timothy J. Colby; Darbonne; Thomas J. Schall; Kuldeep Neote
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Overproduction of recombinant proteins by escherichia coli - employing the combinations of two and three different types of multicopy plasmids - in a 60-litre working volume airlift tower loop reactor
Process Biochemistry, ISSN: 13595113
Lutz Brandes; Xiaoan Wu; Hans E. Maschke; Karl Schügerl
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Neurotrophin-4/5 is a mammalian-specific survival factor for distinct populations of sensory neurons
Journal of Neuroscience, ISSN: 02706474
Alun M. Davies; Antony Horton; Louis E. Burton; Charles H. Schmelzer; Richard L. Vandlen; Rosenthal
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Identification and Structural Analysis of the Tetrasaccharide NeuAcα(2→6)Galβ(1→4)GlcNAcβ(1→3)Fucαl→O-Linked to Serine 61 of Human Factor IX
Biochemistry, ISSN: 15204995 00062960
Reed J. Harris; Basa; Victor Ling; Spellman; Van Halbeek; John Glushka; Kenneth J. Smith
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Peptide Stability in Drug Development: In vitro Peptide Degradation in Plasma and Serum
Annual Reports in Medicinal Chemistry, ISSN: 00657743
Powell
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Thermodynamic Analysis of an Antibody Functional Epitope
Biochemistry, ISSN: 15204995 00062960
Robert F. Kelley; Mark P. O'Connell
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Triply Convergent Synthesis of 15-(Phenoxymethyl) and 4,5-Allenyl Prostaglandins. Preparation of an Individual Isomer of Enprostil
Journal of Organic Chemistry, ISSN: 15206904 00223263
Owen W. Gooding; Colin C. Beard; Gary F. Cooper; Jackson
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Glycoprotein IIb IIIa Antagonists
Annual Reports in Medicinal Chemistry, ISSN: 00657743
Brent Blackburn; Thomas Gadek
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Production of Fusion Protein SpA:: EcoRI in Batch Culture in a 60‐L Airlift Tower Loop Reactor
Biotechnology Progress, ISSN: 15206033 87567938
Lutz Brandes; Xiaoan Wu; Hans E. Maschke; Heike Jürgens; Birgit Reinhardt; Karl Schügerl
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Receptor/ligand interactions in the C-C chemokine family
Advances in Experimental Medicine and Biology, ISSN: 00652598
Thomas J. Schall; John Mak; DiGregorio; Kuldeep Neote
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Evidence supporting a role for cathepsin B in the generation of T cell antigenic epitopes of human growth hormone
Molecular Immunology, ISSN: 01615890
Gillian Bushell; Nelson; Chiu; Christopher Grimley; William J. Henzel; Burnier; Fong
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Homotypic leukocyte aggregation triggered by a monoclonal antibody specific for a novel epitope expressed by the integrin β1 subunit: Conversion of nonresponsive cells by transfecting human integrin α4 subunit cDNA
Journal of Cellular Biochemistry, ISSN: 10974644 07302312
John L. Bednarczyk; James N. Wygant; Margit C. Szabo; Laura Molinari‐Storey; Renz; Fong; Bradley W. McIntyre
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Effects of tumor necrosis factor-α treatment on mortality in murine cytomegalovirus-infected mice
Antiviral Research, ISSN: 01663542
Anderson; Yolanda S. Lie; Mari-Anne L. Low; Fennie
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Optimizing binding and catalysis by phage display
Protein Engineering, Design and Selection, ISSN: 17410134 17410126
James A. Wells; Henry B. Lowman; Matthews
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Determination of type I receptor specificity by the type II receptors for TGF-β or activin
Science, ISSN: 00368075
Reinhard Ebner; Ruey-Hwa Chen; Sean Lawler; Zioncheck; Rik Derynck
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Substrate phage: Selection of protease substrates by monovalent phage display
Science, ISSN: 00368075
Matthews; James A. Wells
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L- and E-selectin can recognize the same naturally occurring ligands on high endothelial venules
Journal of Immunology, ISSN: 00221767
Mebius; Susan R. Watson
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Epstein-Barr virus-derived vectors for transient and stable expression of recombinant proteins
BioTechniques, ISSN: 07366205
Cachianes; Ho; Weber; Steven R. Williams; David V. Goeddel; Leung
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Homotypic leukocyte aggregation triggered by a monoclonal antibody specific for a novel epitope expressed by the integrin β1 subunit: Conversion of nonresponsive cells by transfecting human integrin α4 subunit cDNA
Journal of Cellular Biochemistry, ISSN: 10974644 07302312
John L. Bednarczyk; James N. Wygant; Margit C. Szabo; Laura Molinari‐Storey; Renz; Sherman Fong; Bradley W. McIntyre
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Evidence that the growth hormone receptor mediates differentiation and development of the mammary gland
Endocrinology, ISSN: 19457170 00137227
Mark Feldman; Weifeng Ruan; Cunningham; James A. Wells; David Kleinberg
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Crystallization and stoichiometry of binding of a complex between a rat intestinal Fc receptor and Fc
Journal of Molecular Biology, ISSN: 00222836
Andrew H. Huber; Robert F. Kelley; Louis N. Gastinel; Pamela J. Bjorkman
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Expression, purification, and characterization of recombinant ornatin e, a potent glycoprotein iib-iiia antagonist
Protein Expression and Purification, ISSN: 10465928
Paul Mazur; Dennis; Jana L. Seymour; Lazarus
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Assignment of 1H, 15N, and 13C Resonances, Identification of Elements of Secondary Structure and Determination of the Global Fold of the DNA-Binding Domain of GAL4
Biochemistry, ISSN: 15204995 00062960
Masahiro Shirakawa; Yasuharu Serikawa; Yoshimasa Kyogoku; Wayne J. Fairbrother; Peter E. Wright; Tadayasu Ohkubo
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Mapping of the Binding Interfaces of the Proteins of the Bacterial Phosphotransferase System, HPr and IIAglc
Biochemistry, ISSN: 15204995 00062960
Yuan Chen; Peter E. Wright; Jonathan Reizer; Milton H. Saier Jr.; Wayne J. Fairbrother
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Cysteine Pairing in the Glycoprotein IIbIIIa Antagonist Kistrin Using NMR, Chemical Analysis, and Structure Calculations
Biochemistry, ISSN: 15204995 00062960
Marc Adler; Paul J. Carter; Lazarus; Gerhard Wagner
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Solution Structure of Human Type-α Transforming Growth Factor Determined by Heteronuclear NMR Spectroscopy and Refined by Energy Minimization with Restraints
Biochemistry, ISSN: 15204995 00062960
Franklin J. Moy; Yu-Chin Li; Peter Rauenbuehler; Winkler; Harold A. Scheraga; Gaetano T Montelione
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Synthetic chimeras of mouse growth factor‐associated glandular kallikreins. I. Kinetic properties
Protein Science, ISSN: 1469896X 09618368
Michael Blaber; Paul J. Isackson; Ralph A. Bradshaw; Burnier; James C. Marsters Jr.
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Biosynthesis and function of membrane bound and secreted forms of recombinant CD11b/CD18 (Mac‐1)
Journal of Cellular Biochemistry, ISSN: 10974644 07302312
Berman; Nakamura; Riddle; Chiu; Karen L. Fisher; Mark Champe; Gray; Ward; Fong
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IGF-I is required for normal embryonic growth in mice
Genes and Development, ISSN: 08909369
Powell-Braxton; Hollingshead; Warburton; Mary Dowd; Sharon Pitts-Meek; Dyana K. Dalton; Nancy Gillett; Stewart
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Crystal structure of a sweet tasting protein thaumatin I, at 1·65 Å resolution
Journal of Molecular Biology, ISSN: 00222836
Craig M. Ogata; Paul F. Gordon; De Vos; Sung-Hou Kim
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Synthesis and Vibrational Analysis of a Locked 14-s-cis Conformer of Retinal
Journal of the American Chemical Society, ISSN: 15205126 00027863
Mary E. M. Cromwell; Ronald Gebhard; Xiao-Yuan Li; Elvira S. Batenburg; Johan C.P. Hopman; Johan Lugtenburg; Richard A. Mathies
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RANTES and macrophage inflammatory protein lot induce the migration and activation of normal human eosinophil granulocytes
Journal of Experimental Medicine, ISSN: 15409538 00221007
Antal Rot; Martin Krieger; Thomas Brunner; Stephan C. Bischoff; Thomas J. Schall; Clemens A. Dahinden
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Basis for the use of rhDNase as a therapy in cystic fibrosis
Polymeric Materials Science and Engineering, Proceedings of the ACS Division of Polymeric Materials Science and Engineering, ISSN: 07430515
Pearlman; Steven J. Shire; Cipolla; Daugherty; Thomas W. Patapoff; Ross C. Clark; Gilbert-Andre Keller; Mrsny
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Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms
Journal of Biological Chemistry, ISSN: 00219258
Houck; Leung; Rowland; Jane Winer; Napoleone Ferrara
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Both intrathymic and peripheral selection modulate the differential expression of Vβ among CD4+ and CD8+ T cells
Journal of Experimental Medicine, ISSN: 15409538 00221007
Pamela J. Fink; Kathryn Swan; Gail Turk; Mark Moore; Francis R. Carbone
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